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Gene: Acot5 (acyl-CoA thioesterase 5) Rattus norvegicus

Analyze

No known orthologs.

Symbol:

Acot5

Name:

acyl-CoA thioesterase 5

RGD ID:

1565917

Description:

Predicted to enable fatty acyl-CoA hydrolase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid metabolic process. Orthologous to human ACOT2 (acyl-CoA thioesterase 2); PARTICIPATES IN unsaturated fatty acid biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 3,3',4,4',5-pentachlorobiphenyl.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

acyl-coenzyme A thioesterase 5; LOC503049; MGC156788; RGD1565917; similar to peroxisomal acyl-CoA thioesterase Ic

RGD Orthologs

Alliance Orthologs

More Info

homologs ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Other homologs ²				less info ...
Homo sapiens (human):	ACOT2 (acyl-CoA thioesterase 2)	HGNC	Ensembl, OrthoDB, Panther, PhylomeDB, Treefam
Homo sapiens (human):	ACOT1 (acyl-CoA thioesterase 1)	HGNC	Ensembl, OrthoDB, Panther, PhylomeDB, Treefam
Homo sapiens (human):	ACOT4 (acyl-CoA thioesterase 4)	HGNC	OrthoDB
Homo sapiens (human):	ACOT6 (acyl-CoA thioesterase 6)	HGNC	OrthoDB
Alliance orthologs ³
Mus musculus (house mouse):	Acot5 (acyl-CoA thioesterase 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ACOT2 (acyl-CoA thioesterase 2)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ACOT2 (acyl-CoA thioesterase 2)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Homo sapiens (human):	ACOT1 (acyl-CoA thioesterase 1)	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	C31H5.6	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	C31H5.6	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	K05B2.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	K05B2.4	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	T05E7.1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	T05E7.1	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	acot20	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	W03D8.8	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	W03D8.8	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	acot22	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	acot21	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	acot2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	acot2	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	LOC100498625	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB)

Related Pseudogenes:

Acot5-ps1

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	109,433,062 - 109,439,846 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	6	109,453,391 - 109,461,035 (-)	Ensembl				GRCr8
GRCr8 Ensembl	6	109,433,062 - 109,439,846 (+)	Ensembl				GRCr8
mRatBN7.2	6	103,701,908 - 103,708,696 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	103,701,908 - 103,708,696 (+)	Ensembl				mRatBN7.2
mRatBN7.2 Ensembl	6	103,723,326 - 103,729,482 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	6	103,863,706 - 103,870,504 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	104,162,924 - 104,169,722 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	103,532,373 - 103,539,171 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	6	110,686,459 - 110,693,179 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	6	110,095,999 - 110,102,719 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	6	107,889,610 - 107,896,330 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	6	107,041,952 - 107,048,672 (+)	NCBI		F344_StmMcwi
Rnor_6.0	6	107,550,904 - 107,557,688 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	107,550,904 - 107,557,688 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	6	117,987,407 - 117,994,244 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	6	108,114,686 - 108,122,769 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	6	101,530,218 - 101,537,087 (+)	NCBI		Celera
Cytogenetic Map	6	q31	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

17beta-estradiol (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,4,5,3',4',5'-Hexachlorobiphenyl (EXP)

6-propyl-2-thiouracil (EXP)

bisphenol A (EXP)

cefaloridine (EXP)

Cuprizon (EXP)

doxorubicin (EXP)

fentin chloride (EXP)

indole-3-methanol (EXP)

indometacin (EXP)

N-acetyl-L-cysteine (EXP)

N-nitrosodiethylamine (EXP)

perfluorooctanoic acid (EXP)

pravastatin (EXP)

rotenone (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

trichloroethene (EXP)

zaragozic acid A (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acyl-CoA metabolic process (IBA,IEA)

fatty acid metabolic process (IBA,IEA)

lipid metabolic process (IEA)

Molecular Function

fatty acyl-CoA hydrolase activity (IBA)

thiolester hydrolase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

unsaturated fatty acid biosynthetic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Variants

Variants in Acot5
95 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	19
Count of miRNA genes:	18
Interacting mature miRNAs:	19
Transcripts:	ENSRNOT00000013760
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2293088	Iddm28	Insulin dependent diabetes mellitus QTL 28	5.21		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	6	68767270	135411972	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	88019181	136741135	Rat
1358355	Srcrt4	Stress Responsive Cort QTL 4	6.39		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	106095977	147156653	Rat
61329	Eae9	Experimental allergic encephalomyelitis QTL 9	3.7		body mass (VT:0001259)	change in body weight (CMO:0002045)	6	84490437	129490437	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	101593607	138161926	Rat
1331725	Bp212	Blood pressure QTL 212	3.52475		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	99437079	125323237	Rat
1331789	Rf37	Renal function QTL 37	3.224		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	86494122	112380234	Rat
1331722	Thshl1	Thyroid stimulating hormone level QTL 1	11.7	0.0001	blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	6	99708426	112483760	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	71278722	116278722	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	93560258	136550638	Rat
10054138	Gmadr3	Adrenal mass QTL 3	3.68	0.00045	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	6	90871046	135871046	Rat
1641917	Colcr5	Colorectal carcinoma resistance QTL 5	3.18	0.0009	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	6	98944780	143944780	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	100704576	136029228	Rat
724524	Uae2	Urinary albumin excretion QTL 2	2.7	0.0005	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	79198463	144254945	Rat
737827	Hcar11	Hepatocarcinoma resistance QTL 11	4.4		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	6	46050607	116278722	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	93778632	138778632	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	20859430	113082285	Rat
2293837	Kiddil1	Kidney dilation QTL 1	3.7		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	86867923	110125012	Rat
2293842	Kiddil3	Kidney dilation QTL 3	4.3		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	86867923	110125012	Rat
10054123	Srcrt6	Stress Responsive Cort QTL 6	2.5	0.0043	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	90871046	135871046	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	93560258	136550638	Rat
1576302	Schws4	Schwannoma susceptibility QTL 4		0.0078	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	78204640	123204640	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	93560258	136550638	Rat
1300075	Glom7	Glomerulus QTL 7	5.6	0.0000002	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	6	76937178	121937178	Rat
12801471	Schws9	Schwannoma susceptibility QTL 9			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	101593607	146593607	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
15	4	7	111	81	76	59	9	59	4	179	34	2	94	69	60	17	8	8

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001079709	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC128618	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC128770	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000013760 ⟹ ENSRNOP00000013760

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	6	109,433,062 - 109,439,846 (+)	Ensembl
mRatBN7.2 Ensembl	6	103,701,908 - 103,708,696 (+)	Ensembl
Rnor_6.0 Ensembl	6	107,550,904 - 107,557,688 (+)	Ensembl

RefSeq Acc Id:

NM_001079709 ⟹ NP_001073177

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	109,433,062 - 109,439,846 (+)	NCBI
mRatBN7.2	6	103,701,908 - 103,708,696 (+)	NCBI
Dahl_SR_JrHsd	6	110,686,459 - 110,693,179 (+)	NCBI
Lyon_Normotensive	6	110,095,999 - 110,102,719 (+)	NCBI
Lyon_Hypertensive	6	107,889,610 - 107,896,330 (+)	NCBI
F344_StmMcwi	6	107,041,952 - 107,048,672 (+)	NCBI
Rnor_6.0	6	107,550,904 - 107,557,688 (+)	NCBI
Rnor_5.0	6	117,987,407 - 117,994,244 (-)	NCBI
RGSC_v3.4	6	108,114,686 - 108,122,769 (+)	RGD
Celera	6	101,530,218 - 101,537,087 (+)	RGD

Sequence:

show sequence

GACTCATGCACTTACCTTCCGAAGCCTTTAAATAGCTTGAGTCACAATTTCACCCTGGGTAGTC
TTGACTCCTCACTGTACCCCAGGTCAAGCTTCCTTCTCAGATTGCATAAGGTACTACAGTAAGG
AACAACCCAAGAAAGAAAGGTTCAAGGCCAAGTTTCTCAGGATTGCCAGATGAGAGTAACCTAA
ACCTAAGGGGTTCTTTTGTAAAGCTATACAGGTCGGGGGTAATGATCTATGCAACTCAATCTTT
GTACCTCTATTTCAACATCAGCTTGAGAAAACATGATCATTACTATTGCTTAGCTCTTCTGCAT
ACAGGCCACTGGTATCCCATAAACTGCGGGGAGTTTCACACCGCAATTGCCATGGCAAGTAAGT
AGGACAAGGGTTCCTTCCTTGTCACAGGCTCCAGAAGTCGAGAGACACTATTCACTCCACAGTA
TTCTGATTTTTTTTACTGTGTCAATATGGTGCCAGTAGTGAGCCTGGAGCCCGACAGCCACAGT
TGCTGGGACGAGCCCCTAAGCATTACTGTGCGTGGCCTGGCCCCCGAGCAGCCTGTCACACTAC
ACTCGGCCCTGCGCGACGAGAAGGGCGCGCTCTTCCGAGCCCACGCGCGCTACCGCGCTGATGC
CCACGGAGAGCTGGACCTGGAGCGCGCGCCCGCGCTGGGCGGCAGCTTCACGGGGCTCGAGCCC
ATGGGGCTGATCTGGGCCATGGAACCCGAACGGCCTTTCTGGCGTCTGGTCAAGCGCGACGTGC
AGACGCCCTTCGTGGTGGAGCTGGAGGTGCTGGACGGACACGAGCCGGACGGTCGGCGGCTGCT
GGCGCAGGCGGTGCACGAGCGTCACTTCATGGCTCCAGGGGTGCGGCGCGTGCCCGTGCGCGAG
GGCCGGGTGCGCGCCACGCTCTTCCTGCCTCCAGGAACTGGACCCTTTCCTGGAATCATAGACC
TTTTTGGAATTGGAGGTGGACTTCTGGAATATAGGGCGAGTCTGCTGGCTGCAAAGGGCTTTGC
CGTCATGGCTCTGGCTTATTTTAAGTATGATGACCTCCCTAAGGCTACAGACATCCTTCGTCTG
GAGTACTTTGAAGAAGCTGTGAACTACCTGCTTGGTCACCCTCAGGTCAAGGGTCCAGGAATTG
GCCTGCTGGGGATTTCCAAAGGGGCTGAACTCTGCCTCTCCATGGCCTCTTTCCTGAACGGCAT
CACGGCCGCTGTCATAATCAATGGCTCCATGGTCAATGTTGCTGGAACACTATACTACAAGGAA
GAGAGTCTGCCTGCTTCGAGCATGAATCTAGAACGAATCAGGGTGACCAAAGATGGGTTTAAAG
ATATTATAGATATCCTGACTGTCCCTCCAGAAGGTCCAGACCAGAAAAGCATCATCCCTGTGGA
AAGGTCTGACACGACCTTCCTGTTCCTCGTTAGTCAGGATGACCGCAACTGGAAGAGCGAGTTC
TATGCCAGAGAGGCCTCCAAACGCTTGCAGGCCCATGGGAAGAAAACACCCCAGATCATCTGCT
ACCCAGAAGCAGGGCACTATATTGAGCCCCCTTACTTCCCTTGGTCCAAGGCTGCCCCCAACTC
CCTTTTTGACATGCCTATCATCCTTGGAGGGGAGCCTAGGGCTCATGCCATGGCCCAGGTGGAC
GCTTGGCAGCAACTCCAGATTTTTTTCCACAAACATTTGAGTGGGGACAAGAAGACAATCCCAG
GAAAACTGTGATTTTCTTTGGGTAGTGACATTTCTGGTACTGACCCATCCTAAGAATAGCTGTA
CCTGTTAGGATGTGTTTACAGGTTTGTTTTTTTTTTTCCTTTTAATAAAGTCTTGAAGAGTCCC
TCCCTCCAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001073177	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI28771	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000013760
	ENSRNOP00000013760.3
	ENSRNOP00000073103.3

RefSeq Acc Id:

NP_001073177 ⟸ NM_001079709

- UniProtKB:

A1A5R4 (UniProtKB/TrEMBL), A0A0G2K4M8 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MVPVVSLEPDSHSCWDEPLSITVRGLAPEQPVTLHSALRDEKGALFRAHARYRADAHGELDLER
APALGGSFTGLEPMGLIWAMEPERPFWRLVKRDVQTPFVVELEVLDGHEPDGRRLLAQAVHERH
FMAPGVRRVPVREGRVRATLFLPPGTGPFPGIIDLFGIGGGLLEYRASLLAAKGFAVMALAYFK
YDDLPKATDILRLEYFEEAVNYLLGHPQVKGPGIGLLGISKGAELCLSMASFLNGITAAVIING
SMVNVAGTLYYKEESLPASSMNLERIRVTKDGFKDIIDILTVPPEGPDQKSIIPVERSDTTFLF
LVSQDDRNWKSEFYAREASKRLQAHGKKTPQIICYPEAGHYIEPPYFPWSKAAPNSLFDMPIIL
GGEPRAHAMAQVDAWQQLQIFFHKHLSGDKKTIPGKL

hide sequence

Ensembl Acc Id:

ENSRNOP00000013760 ⟸ ENSRNOT00000013760

Protein Domains

Acyl-CoA thioester hydrolase/bile acid-CoA amino BAAT/Acyl-CoA thioester hydrolase C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-A1A5R4-F1-model_v2	AlphaFold	A1A5R4	1-421	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694718

Promoter ID:

EPDNEW_R5242

Type:

multiple initiation site

Name:

Acot5_1

Description:

acyl-CoA thioesterase 5

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	107,551,272 - 107,551,332	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565917	AgrOrtholog
BioCyc Gene	G2FUF-36842	BioCyc
BioCyc Pathway	PWY-5148 [acyl-CoA hydrolysis]	BioCyc
	PWY-5972 [stearate biosynthesis I (animals)]	BioCyc
	PWY-5996 [oleate biosynthesis II (animals and fungi)]	BioCyc
	PWY-8042 [acylceramide biosynthesis]	BioCyc
	PWY3O-1801 [palmitoleate biosynthesis IV (fungi and animals)]	BioCyc
BioCyc Pathway Image	PWY-5148	BioCyc
	PWY-5972	BioCyc
	PWY-5996	BioCyc
	PWY-8042	BioCyc
	PWY3O-1801	BioCyc
Ensembl Genes	ENSRNOG00000032508	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOG00000053460	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000013760	ENTREZGENE
	ENSRNOT00000013760.6	UniProtKB/TrEMBL
	ENSRNOT00000077555.3	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.2240	UniProtKB/TrEMBL
	3.40.50.1820	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7127435	IMAGE-MGC_LOAD
InterPro	AB_hydrolase	UniProtKB/TrEMBL
	Acyl-CoA_thioEstase_long-chain	UniProtKB/TrEMBL
	BAAT_C	UniProtKB/TrEMBL
	Thio_Ohase/aa_AcTrfase	UniProtKB/TrEMBL
	Thio_Ohase/BAAT_N	UniProtKB/TrEMBL
KEGG Report	rno:503049	UniProtKB/TrEMBL
MGC_CLONE	MGC:156788	IMAGE-MGC_LOAD
NCBI Gene	503049	ENTREZGENE
PANTHER	ACYL-COENZYME A THIOESTERASE 5	UniProtKB/TrEMBL
	ACYL-COENZYME A THIOESTERASE-RELATED	UniProtKB/TrEMBL
Pfam	BAAT_C	UniProtKB/TrEMBL
	Bile_Hydr_Trans	UniProtKB/TrEMBL
PhenoGen	Acot5	PhenoGen
PIRSF	Acyl-CoA_hydro	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000032508	RatGTEx
	ENSRNOG00000053460	RatGTEx
Superfamily-SCOP	SSF53474	UniProtKB/TrEMBL
UniProt	A0A0G2K4M8	ENTREZGENE, UniProtKB/TrEMBL
	A1A5R4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-07	Acot5	acyl-CoA thioesterase 5	RGD1565917_predicted	similar to peroxisomal acyl-CoA thioesterase Ic (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1565917_predicted	similar to peroxisomal acyl-CoA thioesterase Ic (predicted)	LOC503049	similar to peroxisomal acyl-CoA thioesterase Ic	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC503049	similar to peroxisomal acyl-CoA thioesterase Ic			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Annotations - KEGG (archival)

BioCyc Pathways