Zfp26 (zinc finger protein 26) - Rat Genome Database

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Pathways
Gene: Zfp26 (zinc finger protein 26) Rattus norvegicus
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Symbol: Zfp26
Name: zinc finger protein 26
RGD ID: 1565847
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; transcription cis-regulatory region binding activity; and zinc ion binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including ZNF699 (zinc finger protein 699); ZNF778 (zinc finger protein 778); and ZNF836 (zinc finger protein 836); INTERACTS WITH amitrole; gentamycin; (-)-alpha-phellandrene (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC367033; RGD1565847; similar to zinc finger protein 560
RGD Orthologs
Human
Mouse
Bonobo
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8827,235,912 - 27,261,879 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl827,241,522 - 27,261,331 (-)EnsemblGRCr8
mRatBN7.2818,959,656 - 18,985,647 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl818,965,271 - 18,988,325 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx822,985,728 - 23,005,842 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0821,283,569 - 21,303,683 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0819,195,015 - 19,215,150 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0821,444,833 - 21,466,474 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl821,448,618 - 21,458,379 (-)Ensemblrn6Rnor6.0
Rnor_5.0821,503,262 - 21,524,028 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4819,441,643 - 19,461,773 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera820,360,451 - 20,380,714 (-)NCBICelera
Cytogenetic Map8q13NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
obesity  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nuclear body  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Zfp26
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8827,235,912 - 27,261,879 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl827,241,522 - 27,261,331 (-)EnsemblGRCr8
mRatBN7.2818,959,656 - 18,985,647 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl818,965,271 - 18,988,325 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx822,985,728 - 23,005,842 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0821,283,569 - 21,303,683 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0819,195,015 - 19,215,150 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0821,444,833 - 21,466,474 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl821,448,618 - 21,458,379 (-)Ensemblrn6Rnor6.0
Rnor_5.0821,503,262 - 21,524,028 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4819,441,643 - 19,461,773 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera820,360,451 - 20,380,714 (-)NCBICelera
Cytogenetic Map8q13NCBI
ZNF778
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381689,217,703 - 89,237,141 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1689,217,692 - 89,237,141 (+)Ensemblhg38GRCh38
GRCh371689,284,111 - 89,303,549 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361687,811,612 - 87,822,864 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1674,349,908 - 74,361,295 (+)NCBICelera
Cytogenetic Map16q24.3NCBI
HuRef1674,983,143 - 74,994,997 (+)NCBIHuRef
CHM1_11690,695,090 - 90,707,222 (+)NCBICHM1_1
T2T-CHM13v2.01695,297,944 - 95,317,628 (+)NCBIT2T-CHM13v2.0
Zfp26
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,338,457 - 20,371,465 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl920,339,745 - 20,371,458 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38920,428,318 - 20,460,169 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl920,428,449 - 20,460,162 (-)Ensemblmm10GRCm38
MGSCv37920,232,762 - 20,264,604 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36920,182,960 - 20,210,562 (-)NCBIMGSCv36mm8
Celera917,705,428 - 17,737,274 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.55NCBI
LOC100994304
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21899,017,510 - 99,039,425 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116104,931,925 - 104,951,466 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01669,984,952 - 69,985,889 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11689,598,533 - 89,599,774 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1689,587,595 - 89,595,023 (+)EnsemblpanPan2panpan1.1
PanPan1.1 Ensembl1689,587,595 - 89,595,023 (+)NCBIpanPan2panpan1.1
ZNF778
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1574,583,488 - 74,595,533 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl574,589,788 - 74,595,135 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666047940,024 - 950,520 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Zfp26
124 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:348
Count of miRNA genes:216
Interacting mature miRNAs:247
Transcripts:ENSRNOT00000038084
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357398Slep3Serum leptin concentration QTL 33.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
9590084Insglur5Insulin/glucose ratio QTL 518.540.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)8132882639Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
2302367Slep5Serum leptin concentration QTL 53.43blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)81799410550763951Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat

Markers in Region
D8Rat68  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2818,984,168 - 18,984,364 (+)MAPPERmRatBN7.2
Rnor_6.0821,464,919 - 21,465,112NCBIRnor6.0
Rnor_5.0821,522,570 - 21,522,763UniSTSRnor5.0
RGSC_v3.4819,460,544 - 19,460,738RGDRGSC3.4
RGSC_v3.4819,460,545 - 19,460,738UniSTSRGSC3.4
Celera820,379,486 - 20,379,679UniSTS
RGSC_v3.1819,460,544 - 19,460,738RGD
SHRSP x BN Map812.9UniSTS
SHRSP x BN Map812.9RGD
Cytogenetic Map8q13UniSTS
BE119927  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2818,965,296 - 18,965,485 (+)MAPPERmRatBN7.2
Rnor_6.0821,445,637 - 21,445,825NCBIRnor6.0
Rnor_5.0821,503,288 - 21,503,476UniSTSRnor5.0
RGSC_v3.4819,441,669 - 19,441,857UniSTSRGSC3.4
Celera820,360,477 - 20,360,665UniSTS
Cytogenetic Map8q13UniSTS
AU049231  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2818,978,606 - 18,978,899 (+)MAPPERmRatBN7.2
Rnor_6.0821,458,949 - 21,459,241NCBIRnor6.0
Rnor_5.0821,516,600 - 21,516,892UniSTSRnor5.0
RGSC_v3.4819,454,981 - 19,455,273UniSTSRGSC3.4
Celera820,373,815 - 20,374,107UniSTS
Cytogenetic Map8q13UniSTS
Zfp26  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2818,967,735 - 18,968,036 (+)MAPPERmRatBN7.2
Rnor_6.0821,448,076 - 21,448,376NCBIRnor6.0
Rnor_5.0821,505,727 - 21,506,027UniSTSRnor5.0
RGSC_v3.4819,444,108 - 19,444,408UniSTSRGSC3.4
Celera820,362,916 - 20,363,216UniSTS
Cytogenetic Map8q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000038084   ⟹   ENSRNOP00000037843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl827,241,522 - 27,261,331 (-)Ensembl
mRatBN7.2 Ensembl818,965,271 - 18,975,418 (-)Ensembl
Rnor_6.0 Ensembl821,449,176 - 21,458,379 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000078192   ⟹   ENSRNOP00000072254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl827,241,522 - 27,261,331 (-)Ensembl
mRatBN7.2 Ensembl818,965,271 - 18,988,325 (-)Ensembl
Rnor_6.0 Ensembl821,448,618 - 21,453,190 (-)Ensembl
RefSeq Acc Id: NM_001108995   ⟹   NP_001102465
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8827,241,522 - 27,261,649 (-)NCBI
mRatBN7.2818,965,271 - 18,985,399 (-)NCBI
Rnor_6.0821,445,611 - 21,466,147 (-)NCBI
Rnor_5.0821,503,262 - 21,524,028 (-)NCBI
RGSC_v3.4819,441,643 - 19,461,773 (-)RGD
Celera820,360,451 - 20,380,714 (-)RGD
Sequence:
RefSeq Acc Id: XM_006242652   ⟹   XP_006242714
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8827,235,912 - 27,261,879 (-)NCBI
mRatBN7.2818,959,656 - 18,985,642 (-)NCBI
Rnor_6.0821,444,833 - 21,466,474 (-)NCBI
Rnor_5.0821,503,262 - 21,524,028 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242653   ⟹   XP_006242715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8827,235,912 - 27,261,663 (-)NCBI
mRatBN7.2818,959,656 - 18,985,333 (-)NCBI
Rnor_6.0821,444,833 - 21,466,069 (-)NCBI
Rnor_5.0821,503,262 - 21,524,028 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039081831   ⟹   XP_038937759
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8827,235,912 - 27,261,743 (-)NCBI
mRatBN7.2818,959,656 - 18,985,645 (-)NCBI
RefSeq Acc Id: NP_001102465   ⟸   NM_001108995
- UniProtKB: A0A0G2K2I4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242714   ⟸   XM_006242652
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2I4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242715   ⟸   XM_006242653
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2I4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000037843   ⟸   ENSRNOT00000038084
Ensembl Acc Id: ENSRNOP00000072254   ⟸   ENSRNOT00000078192
RefSeq Acc Id: XP_038937759   ⟸   XM_039081831
- Peptide Label: isoform X2
Protein Domains
C2H2-type   KRAB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LMA0-F1-model_v2 AlphaFold F1LMA0 1-956 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565847 AgrOrtholog
BioCyc Gene G2FUF-31477 BioCyc
Ensembl Genes ENSRNOG00000025937 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038084 ENTREZGENE
  ENSRNOT00000038084.8 UniProtKB/TrEMBL
  ENSRNOT00000078192 ENTREZGENE
  ENSRNOT00000078192.3 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.140 UniProtKB/TrEMBL
  Classic Zinc Finger UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7930337 IMAGE-MGC_LOAD
InterPro GLI_C2H2-zinc-finger UniProtKB/TrEMBL
  KRAB_dom_sf UniProtKB/TrEMBL
  Krueppel-associated_box UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:367033 UniProtKB/TrEMBL
MGC_CLONE MGC:188409 IMAGE-MGC_LOAD
NCBI Gene 367033 ENTREZGENE
PANTHER C2H2-TYPE DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  PAIR-RULE PROTEIN ODD-PAIRED UniProtKB/TrEMBL
  TRANSCRIPTIONAL REPRESSOR PROTEIN YY UniProtKB/TrEMBL
  ZINC FINGER PROTEIN 143 UniProtKB/TrEMBL
  ZINC FINGER PROTEIN ZIC AND GLI UniProtKB/TrEMBL
Pfam KRAB UniProtKB/TrEMBL
  zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zfp26 PhenoGen
PROSITE KRAB UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000025937 RatGTEx
SMART KRAB UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP Krueppel-associated_box UniProtKB/TrEMBL
  SSF57667 UniProtKB/TrEMBL
UniProt A0A0G2K2I4 ENTREZGENE, UniProtKB/TrEMBL
  B2RYA9_RAT UniProtKB/TrEMBL
  F1LMA0_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-01-22 Zfp26  zinc finger protein 26  RGD1565847  similar to zinc finger protein 560   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1565847  similar to zinc finger protein 560   RGD1565847_predicted  similar to zinc finger protein 560 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565847_predicted  similar to zinc finger protein 560 (predicted)  LOC367033  similar to zinc finger protein 560  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC367033  similar to zinc finger protein 560      Symbol and Name status set to provisional 70820 PROVISIONAL