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Gene: Tasl (TLR adaptor interacting with endolysosomal SLC15A4) Rattus norvegicus

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Symbol:

Tasl

Name:

TLR adaptor interacting with endolysosomal SLC15A4

RGD ID:

1565785

Description:

Predicted to be involved in positive regulation of toll-like receptor 7 signaling pathway; positive regulation of toll-like receptor 8 signaling pathway; and regulation of lysosomal lumen pH. Predicted to be located in endolysosome membrane. Orthologous to human TASL (TLR adaptor interacting with endolysosomal SLC15A4); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acetamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

hypothetical protein LOC501570; LOC501570; RGD1565785; similar to chromosome X open reading frame 21; TLR adapter interacting with SLC15A4 on the lysosome; uncharacterized protein CXorf21 homolog; uncharacterized protein LOC501570

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	54,354,755 - 54,373,930 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	54,312,036 - 54,374,144 (+)	Ensembl				GRCr8
mRatBN7.2	X	50,403,962 - 50,423,141 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	50,361,248 - 50,423,269 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	51,733,739 - 51,752,906 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	55,234,110 - 55,253,281 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	52,865,125 - 52,884,294 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	54,390,733 - 54,409,466 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	54,390,733 - 54,409,466 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	54,590,577 - 54,609,310 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	72,641,314 - 72,660,592 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	50,943,855 - 50,963,014 (+)	NCBI		Celera
Cytogenetic Map	X	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (EXP)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

Cuprizon (EXP)

formaldehyde (ISO)

iron atom (ISO)

iron(0) (ISO)

methapyrilene (ISO)

methyl methanesulfonate (ISO)

Moniliformin (ISO)

nickel atom (ISO)

sulforaphane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of innate immune response (IEA,ISO)

positive regulation of toll-like receptor 7 signaling pathway (IEA,ISO)

positive regulation of toll-like receptor 8 signaling pathway (IEA,ISO)

regulation of lysosomal lumen pH (IBA,IEA,ISO)

regulation of toll-like receptor signaling pathway (IEA)

Cellular Component

cytosol (IEA,ISO)

endolysosome membrane (IEA,ISO)

nucleoplasm (IEA,ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:31001245

Genomics

Comparative Map Data

Tasl
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	54,354,755 - 54,373,930 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	54,312,036 - 54,374,144 (+)	Ensembl				GRCr8
mRatBN7.2	X	50,403,962 - 50,423,141 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	50,361,248 - 50,423,269 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	51,733,739 - 51,752,906 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	55,234,110 - 55,253,281 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	52,865,125 - 52,884,294 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	54,390,733 - 54,409,466 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	54,390,733 - 54,409,466 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	54,590,577 - 54,609,310 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	72,641,314 - 72,660,592 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	50,943,855 - 50,963,014 (+)	NCBI		Celera
Cytogenetic Map	X	q21	NCBI

TASL
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	30,558,809 - 30,577,766 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	30,557,707 - 30,577,766 (-)	Ensembl			hg38	GRCh38
GRCh37	X	30,576,926 - 30,595,883 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	30,486,862 - 30,505,835 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	X	30,336,597 - 30,355,571	NCBI
Celera	X	34,698,462 - 34,717,597 (-)	NCBI		Celera
Cytogenetic Map	X	p21.2	NCBI
HuRef	X	28,314,203 - 28,333,300 (-)	NCBI		HuRef
CHM1_1	X	30,607,829 - 30,626,921 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	30,150,830 - 30,169,806 (-)	NCBI		T2T-CHM13v2.0

Tasl
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	84,820,445 - 84,935,105 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	84,913,960 - 84,935,105 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	X	85,776,968 - 85,891,499 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	85,870,354 - 85,891,499 (+)	Ensembl			mm10	GRCm38
MGSCv37	X	83,115,612 - 83,136,838 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	X	82,122,992 - 82,144,218 (+)	NCBI		MGSCv36	mm8
Celera	X	77,064,940 - 77,086,117 (+)	NCBI		Celera
Cytogenetic Map	X	C1	NCBI
cM Map	X	39.39	NCBI

Tasl
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955531	267,216 - 293,127 (+)	Ensembl
ChiLan1.0	NW_004955531	207,614 - 293,127 (+)	NCBI	ChiLan1.0	ChiLan1.0

TASL
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	32,351,736 - 32,372,522 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	32,355,112 - 32,375,901 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	23,159,321 - 23,178,192 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	30,716,157 - 30,735,059 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	30,716,617 - 30,717,522 (-)	Ensembl			panPan2	panpan1.1

TASL
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	25,664,361 - 25,679,044 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	30,639,199 - 30,653,660 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	25,695,592 - 25,710,287 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	X	25,741,501 - 25,755,942 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	25,732,975 - 25,747,432 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	25,829,165 - 25,843,624 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Tasl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	18,534,520 - 18,554,443 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936553	6,628,131 - 6,629,027 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936553	6,628,131 - 6,629,027 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TASL
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	26,365,027 - 26,384,760 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	X	26,363,808 - 26,384,933 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	28,635,141 - 28,651,261 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TASL
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	28,953,805 - 28,973,055 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	28,954,266 - 28,955,171 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666056	30,933,802 - 30,953,001 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tasl
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624762	25,430,926 - 25,448,114 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624762	25,427,519 - 25,448,180 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Tasl
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	X	44,264,609 - 44,283,925 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tasl
53 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	216
Count of miRNA genes:	151
Interacting mature miRNAs:	174
Transcripts:	ENSRNOT00000004977
Prediction methods:	Microtar, Miranda, Pita, Pita,Microtar, Pita,Targetscan, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
738035	Stresp1	Stress response QTL 1	4.96	0.000011	stress-related behavior trait (VT:0010451)	defensive burying - coping	X	45182909	117740458	Rat
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	44930883	89930883	Rat

Markers in Region

DXGot154

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	X	50,407,965 - 50,408,262 (+)	MAPPER	mRatBN7.2
Rnor_6.0	X	54,394,782 - 54,395,078	NCBI	Rnor6.0
Rnor_5.0	X	54,594,626 - 54,594,922	UniSTS	Rnor5.0
RGSC_v3.4	X	72,645,579 - 72,645,875	UniSTS	RGSC3.4
Celera	X	50,947,903 - 50,948,199	UniSTS
Cytogenetic Map	X	q22	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	11	62	143	91	90	59	92	59	6	340	185	11	117	72	90	31	9	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109318	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000004977 ⟹ ENSRNOP00000004977

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	54,354,639 - 54,374,144 (+)	Ensembl
mRatBN7.2 Ensembl	X	50,403,845 - 50,423,269 (+)	Ensembl
Rnor_6.0 Ensembl	X	54,390,733 - 54,409,466 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119697 ⟹ ENSRNOP00000090482

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	54,312,036 - 54,374,144 (+)	Ensembl
mRatBN7.2 Ensembl	X	50,361,248 - 50,423,269 (+)	Ensembl

RefSeq Acc Id:

NM_001109318 ⟹ NP_001102788

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	54,354,755 - 54,373,930 (+)	NCBI
mRatBN7.2	X	50,403,962 - 50,423,141 (+)	NCBI
Rnor_6.0	X	54,390,733 - 54,409,466 (+)	NCBI
Rnor_5.0	X	54,590,577 - 54,609,310 (+)	NCBI
RGSC_v3.4	X	72,641,314 - 72,660,592 (+)	RGD
Celera	X	50,943,855 - 50,963,014 (+)	RGD

Sequence:

show sequence

GGCAGCTCAGTGTCTTAGTGGCCTCGTCTGTGAGAGGCTTGAGAACGTTTTGCAAAGAGCCCTG
ACCAGCTAGTTCTTCTCTATTTGATCAGTCATTGTGTTGCTACAGGATTCAAGGAGCAGACTCT
GGTGAAGAATGCTGTCAGAAGGATATCTCAGTGGACTTACCTACTGGAATGACATTCATTGGAA
TTGTGCATCTTATAATGAACCGGTGGCTGGGGACCAGGGTGAGGAGACAAGTTCCGTTGCTGCT
CTTTCATATTCCTCTGTGGATGAAACACAAGTTCAAAGTGTTTATGTGAGCTGCAAATCCTCTG
GGAAGTTTATTTCATCAGTGCATGCAAGAGCGAGTCAGCACAGCAGAAGCCAGAGCAGAACAGT
GCTGCAGGCAAACTCCAACCCGGTATTTGAAAGTCCGACCTTAGCCGCAGTTGGCATATGCAGA
GATGTGATCAGGGAAACCTACCTGGTTCCACCTTCTTGTAAAAGTATTTGCAAAAATTACAATG
ACTTACATATTGCAGGGGGGCAGGTGATGGCCATTAACTCAGTAATGGCAGATTTTCCCTCTGA
GAGCAGCTTTGAAGATGGTCCTTTGCTAAAGTCATCTGAGATTTCTTTGTCCATGGAGGATTCC
ATTTCCACTCAGTTCACTGAACTTCCCCTCAAACCTATCCAGCGGTACTCATCCTACTGGAGGA
TAACCAGCATCAAAGAGAAAAACAGCCTGCAAATGCAGAAGCCTATTTCAAATGCAGTGCTCAA
CGAGTACCTGGAACAGAAGGTGGTGGAGTTATATAAGCAATACATTATGGACACTGTGTTTCAC
GACAGTTCTCCTACCCAGATTCTGGCATCAGAATTCATCATGACAAATGTAGATCAAATTAGTC
TTCAAGTGTCTAAAGAGAAGAACCTGGACACTTCGAAAGTCAAGGACATAGTTATTAGCCATCT
ATTGCAGTTGGTATCATCTGAGATCAGCACCCCCAGTCTCCATATTTCTCAGTATAGCGATATA
ACTCCATAGAGAAGATTCCTGTCAATTCCCCTCATTCCTATCAATCCCAAGGGAATGTTGTATT
CATTTGATCAGAGGATGTGATGGAGGGAATTATGGAAGGGAATTAATGACTAGTAAAGGGGAGT
TTGAGAAATCTCACACTGAAGGGATACAGGCAGAGGGACCACAAGAATGGTTTCAAGGGTAAGT
TTATATAGAATCAAAGCAAAAATAAAAATGATCACAGAGAGAAAGAAGATATTGTGACTTAAAT
TTAGGAGTACTGGAATTGGAAGATATACCAAACCAGGAACAAAAGGAAACACTATGGCAAACTA
GAAAGTCAACTGATTTGAGAATTGGGAATTAAACACCTGTTTCCTATTTATATACATTTTGCCT
AGGTTGTTTCTTCTGGAGAGAAATGGACCACAAGAAGGTTGTAAATTCCAGTGGACTGACATTT
TTCCAAGTATAAGCTTGTATCTTTTCCCTCTATGCTGTATCAGTAAGTCATTTAGGTATACTCT
TTGTAAATATTAAATGAATAAC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001102788	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL96049	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000004977
	ENSRNOP00000004977.3
	ENSRNOP00000090482.1

RefSeq Acc Id:

NP_001102788 ⟸ NM_001109318

- UniProtKB:

D3ZRK2 (UniProtKB/TrEMBL), A6IPW4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLSEGYLSGLTYWNDIHWNCASYNEPVAGDQGEETSSVAALSYSSVDETQVQSVYVSCKSSGKF
ISSVHARASQHSRSQSRTVLQANSNPVFESPTLAAVGICRDVIRETYLVPPSCKSICKNYNDLH
IAGGQVMAINSVMADFPSESSFEDGPLLKSSEISLSMEDSISTQFTELPLKPIQRYSSYWRITS
IKEKNSLQMQKPISNAVLNEYLEQKVVELYKQYIMDTVFHDSSPTQILASEFIMTNVDQISLQV
SKEKNLDTSKVKDIVISHLLQLVSSEISTPSLHISQYSDITP

hide sequence

Ensembl Acc Id:

ENSRNOP00000004977 ⟸ ENSRNOT00000004977

Ensembl Acc Id:

ENSRNOP00000090482 ⟸ ENSRNOT00000119697

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZRK2-F1-model_v2	AlphaFold	D3ZRK2	1-298	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565785	AgrOrtholog
BioCyc Gene	G2FUF-2343	BioCyc
Ensembl Genes	ENSRNOG00000003748	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000004977	ENTREZGENE
	ENSRNOT00000004977.6	UniProtKB/TrEMBL
	ENSRNOT00000119697.2	UniProtKB/TrEMBL
InterPro	DUF4569	UniProtKB/TrEMBL
KEGG Report	rno:501570	UniProtKB/TrEMBL
NCBI Gene	501570	ENTREZGENE
PANTHER	PTHR14889	UniProtKB/TrEMBL
	TLR ADAPTER INTERACTING WITH SLC15A4 ON THE LYSOSOME	UniProtKB/TrEMBL
Pfam	DUF4569	UniProtKB/TrEMBL
PhenoGen	Tasl	PhenoGen
RatGTEx	ENSRNOG00000003748	RatGTEx
UniProt	A6IPW4	ENTREZGENE, UniProtKB/TrEMBL
	D3ZRK2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-08-13	Tasl	TLR adaptor interacting with endolysosomal SLC15A4	RGD1565785	similar to chromosome X open reading frame 21	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1565785	similar to chromosome X open reading frame 21	RGD1565785_predicted	similar to chromosome X open reading frame 21 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1565785_predicted	similar to chromosome X open reading frame 21 (predicted)	LOC501570	similar to chromosome X open reading frame 21	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC501570	similar to chromosome X open reading frame 21			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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