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Gene: Shisa3 (shisa family member 3) Rattus norvegicus

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Symbol:

Shisa3

Name:

shisa family member 3

RGD ID:

1565710

Description:

Predicted to act upstream of or within negative regulation of canonical Wnt signaling pathway. Predicted to be located in membrane. Orthologous to human SHISA3 (shisa family member 3); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC498356; protein shisa-3 homolog; RGD1565710; shisa homolog 3; shisa homolog 3 (Xenopus laevis); similar to MGC68837 protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SHISA3 (shisa family member 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Shisa3 (shisa family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Shisa3 (shisa family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SHISA3 (shisa family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SHISA3 (shisa family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Shisa3 (shisa family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SHISA3 (shisa family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SHISA3 (shisa family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Shisa3 (shisa family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Shisa3 (shisa family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Shisa3 (shisa family member 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SHISA3 (shisa family member 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	shisa3 (shisa family member 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	shisa3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	40,917,563 - 40,922,135 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	40,917,564 - 40,922,135 (-)	Ensembl				GRCr8
mRatBN7.2	14	40,563,672 - 40,568,244 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	40,563,673 - 40,568,244 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	40,910,502 - 40,915,074 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	42,210,574 - 42,215,146 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	40,691,360 - 40,695,932 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	42,216,653 - 42,221,225 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	42,216,654 - 42,221,225 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	42,013,406 - 42,017,978 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	43,175,486 - 43,180,058 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	39,721,342 - 39,725,914 (-)	NCBI		Celera
Cytogenetic Map	14	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (EXP)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,7-dihydropurine-6-thione (EXP)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

cadmium dichloride (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

clobetasol (ISO)

copper atom (ISO)

copper(0) (ISO)

dimethylarsinic acid (EXP)

ethanol (ISO)

folic acid (ISO)

fulvestrant (ISO)

L-citrulline (ISO)

lipopolysaccharide (ISO)

malathion (ISO)

manganese(II) chloride (EXP)

mercaptopurine (EXP)

mono(2-ethylhexyl) phthalate (ISO)

N-methyl-4-phenylpyridinium (EXP)

N-nitrosodimethylamine (EXP)

nickel atom (ISO)

okadaic acid (ISO)

paracetamol (EXP)

pentanal (ISO)

perfluorohexanesulfonic acid (ISO)

permethrin (ISO)

propanal (ISO)

purine-6-thiol (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium dichromate (EXP)

sodium fluoride (EXP)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

triclosan (ISO)

trovafloxacin (ISO)

valproic acid (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of canonical Wnt signaling pathway (ISO)

Cellular Component

membrane (IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Shisa3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	40,917,563 - 40,922,135 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	14	40,917,564 - 40,922,135 (-)	Ensembl				GRCr8
mRatBN7.2	14	40,563,672 - 40,568,244 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	40,563,673 - 40,568,244 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	14	40,910,502 - 40,915,074 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	42,210,574 - 42,215,146 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	40,691,360 - 40,695,932 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	42,216,653 - 42,221,225 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	42,216,654 - 42,221,225 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	14	42,013,406 - 42,017,978 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	14	43,175,486 - 43,180,058 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	14	39,721,342 - 39,725,914 (-)	NCBI		Celera
Cytogenetic Map	14	p11	NCBI

SHISA3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	4	42,397,488 - 42,402,487 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	4	42,397,488 - 42,402,487 (+)	Ensembl			hg38	GRCh38
GRCh37	4	42,399,505 - 42,404,504 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	4	42,094,613 - 42,099,261 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	4	42,847,702 - 42,852,350 (+)	NCBI		Celera
Cytogenetic Map	4	p13	NCBI
HuRef	4	41,721,064 - 41,725,712 (+)	NCBI		HuRef
CHM1_1	4	42,400,127 - 42,404,775 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	4	42,371,349 - 42,376,348 (+)	NCBI		T2T-CHM13v2.0

Shisa3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	67,765,226 - 67,771,330 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	67,765,225 - 67,780,895 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	5	67,607,883 - 67,613,987 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	67,607,882 - 67,623,552 (+)	Ensembl			mm10	GRCm38
MGSCv37	5	67,999,122 - 68,003,511 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	5	67,887,018 - 67,891,407 (+)	NCBI		MGSCv36	mm8
Celera	5	64,899,945 - 64,905,332 (+)	NCBI		Celera
Cytogenetic Map	5	C3.1	NCBI
cM Map	5	36.15	NCBI

Shisa3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955443	5,365,791 - 5,372,108 (-)	Ensembl
ChiLan1.0	NW_004955443	5,367,306 - 5,372,091 (-)	NCBI	ChiLan1.0	ChiLan1.0

SHISA3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	3	42,580,469 - 42,585,747 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	4	42,771,347 - 42,776,625 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	4	36,718,938 - 36,723,924 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	4	42,566,944 - 42,572,098 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	4	42,567,291 - 42,572,098 (+)	Ensembl			panPan2	panpan1.1

SHISA3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	13	39,358,206 - 39,360,723 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	13	39,358,607 - 39,359,730 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	13	39,333,616 - 39,338,124 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	13	39,847,323 - 39,851,823 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	13	39,846,741 - 39,851,805 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	13	39,535,571 - 39,540,095 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	13	39,648,613 - 39,653,152 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	13	40,113,373 - 40,117,919 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Shisa3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405285	36,741,476 - 36,745,878 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936482	9,551,933 - 9,556,794 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936482	9,551,933 - 9,556,763 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SHISA3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	8	33,374,265 - 33,378,951 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	8	33,373,633 - 33,379,039 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	8	35,095,667 - 35,096,819 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SHISA3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	27	7,939,248 - 7,946,897 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	27	7,940,285 - 7,943,677 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666047	54,236,396 - 54,241,498 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Shisa3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624761	24,511,759 - 24,519,251 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624761	24,514,251 - 24,519,253 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Shisa3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	11	24,718,457 - 24,723,035 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Shisa3
10 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	459
Count of miRNA genes:	258
Interacting mature miRNAs:	308
Transcripts:	ENSRNOT00000036103
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2313089	Bss81	Bone structure and strength QTL 81	3.4	0.0001	body length (VT:0001256)	body length, nose to rump (CMO:0000079)	14	38023710	83023710	Rat
70214	Niddm28	Non-insulin dependent diabetes mellitus QTL 28	4.06		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	14	39009444	84009444	Rat
1300154	Bp189	Blood pressure QTL 189	3.04		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	14	31238080	72970315	Rat
70187	Pancm5	Pancreatic morphology QTL 5	16.7		pancreas mass (VT:0010144)	pancreas weight to body weight ratio (CMO:0000630)	14	30674469	85041098	Rat
631523	Pia13	Pristane induced arthritis QTL 13	3.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	14	33424686	102238540	Rat
1358296	Ael3	Aortic elastin QTL 3	3.7	0.00051	aorta elastin amount (VT:0003905)	aortic elastin	14	8621398	53621398	Rat
61420	Pia6	Pristane induced arthritis QTL 6	4.9		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	14	18915454	42433608	Rat
2313100	Bss82	Bone structure and strength QTL 82	3	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	14	38023710	83023710	Rat
7387267	Uae42	Urinary albumin excretion QTL 42		0.61	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	14	22521517	67521517	Rat
631839	Niddm37	Non-insulin dependent diabetes mellitus QTL 37	3.37		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	14	11334716	100078267	Rat
2313397	Coatc1	Coat color QTL1			coat/hair pigmentation trait (VT:0010463)	coat/hair color measurement (CMO:0001808)	14	18895192	63895192	Rat
631262	Tcas4	Tongue tumor susceptibility QTL 4	7.29		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	14	17906726	54251504	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41415516	Rat
2313048	Bss84	Bone structure and strength QTL 84	3.1	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	14	38023710	83023710	Rat
2302045	Pia39	Pristane induced arthritis QTL 39	4.9	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G2a level (CMO:0002116)	14	8621398	53621398	Rat
738037	Hcas6	Hepatocarcinoma susceptibility QTL 6	2.93		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	14	39411170	87582095	Rat
2313084	Bss83	Bone structure and strength QTL 83	2.9	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	14	38023710	83023710	Rat

Markers in Region

BE095714

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	40,564,376 - 40,564,528 (+)	MAPPER	mRatBN7.2
Rnor_6.0	14	42,217,358 - 42,217,509	NCBI	Rnor6.0
Rnor_5.0	14	42,014,111 - 42,014,262	UniSTS	Rnor5.0
RGSC_v3.4	14	43,176,191 - 43,176,342	UniSTS	RGSC3.4
Celera	14	39,722,047 - 39,722,198	UniSTS
Cytogenetic Map	14	p11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
14	11	56	148	91	90	59	60	59	6	294	148	10	127	65	84	31	9	9

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC168960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000036103 ⟹ ENSRNOP00000033959

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	14	40,917,564 - 40,922,135 (-)	Ensembl
mRatBN7.2 Ensembl	14	40,563,673 - 40,568,244 (-)	Ensembl
Rnor_6.0 Ensembl	14	42,216,654 - 42,221,225 (-)	Ensembl

RefSeq Acc Id:

NM_001109087 ⟹ NP_001102557

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	40,917,563 - 40,922,135 (-)	NCBI
mRatBN7.2	14	40,563,672 - 40,568,244 (-)	NCBI
Rnor_6.0	14	42,216,653 - 42,221,225 (-)	NCBI
Rnor_5.0	14	42,013,406 - 42,017,978 (-)	NCBI
RGSC_v3.4	14	43,175,486 - 43,180,058 (-)	RGD
Celera	14	39,721,342 - 39,725,914 (-)	RGD

Sequence:

show sequence

GCACTTGGCCGAGACTCCGCTGTCTCCGGCCTGCGTGACAGTCAGCGGCCGGAGCGGAATTAGC
CGCTGGTCCCCGGGACCTGCACGTGGAGAGCCAAGCTGAACTCCCAGCTCTGCCCGGTACCCGG
CGACAACCCACGATCCGGACACCGCCCGGCCTTGGGGTTGGTTGTCCTGGGGCTCGACGGCCCG
CAAGGAAAGCTGGGTGGGAGGCGGCCCGGGCCCCGGTGCCCCTAGCGCGATGAGCCCCGCTAAG
GGCGGCCGTTGCTTCTGTGGCAGCCTCCGTGGTGGCCTCCCGCGAGCCCTGGTCCCCTCTCCCT
CGCGCACCATGCTGTCCTCCGGCCAGTGGAGCCCGCAGCGCAGCCCACGGCTCCTGCCCAGCCA
CTGCTAACCCAGGAGAGCGCGTTCTTGACCGGGAGGTCAACTGGCCGCGTGGTGCCTCGGGGAG
GCGGAACCGTGGTCCCCGGAGCCCCGGCTCCGCCCTCCGACTCTCCAGCTGCCACTGGGCGCGG
GGGCGGCGATGGGGGCGCTGCTGGCGCTCTGTCTGCTTGTGGGCTTGCTGCGCTGGGGCCCGGC
GGGCGCACAGCAGCCTGGGGAATACTGCCACGGCTGGGTGGACGCGCAGGGCAACTATCACGAA
GGGTTCCAGTGCCCCGAGGACTTCGACACGCAGGACGCCACCATCTGCTGCGGTTCTTGTGCGC
TGCGCTACTGCTGCGCTGCAGCCGACGCCAGGTTGGAGCAGGGCGGCTGCACCAACGACCGGGG
AGAGCTGGAGCATCCTGGCATCACCGCGCAGCCTGTCTACGTCCCCTTCCTGATCGTCGGCTCC
ATCTTCATTGCCTTCATCATTTTGGGCTCTTTAGTGGCGATCTATTGCTGCACCTGCTTGAGGC
CCAAGGAGCCCTCCCAGCAACCCATCCGCTTCTCACTCCGAAGCTATCAGACAGAGACCTTGCC
CATGATCCTCACCTCCACCAGCCTCAGAACCGCTTCCAGGCAGTCCAGCACGGCCACTAGTTCC
AGCTCCACGGGGGGGTCTGTCCGAAGGTTCTCTTTCGCCAGGGCTGAGCCAAACTGCTTGGTAC
CCTCATCGCCCCCACCTTACACCACCGGCCACACCATACACCTAACCCAACCATCCGGTTTCCT
GGTGTCACCCCAGTATTTTGCATACCCTCTCCAGCAGGAGCCCCCGTTACCTGGGAAGAGCTGT
CCAGATTTCAGTTCTAGTTGATGGGCAGTGGCTGTGGCTAGGCCATGCAGCGAGCGGCAGCCAG
GCGGAGCGTCGCTGTCTCAGCCAAGCCACTCTCACTTCTGAGGAAATTTGTGGTAACCCATCAT
GCTCATGAAAGGAAGGTCCAGGAAGATGAAGCACTTTCTGGTCTTGAGGTTCCTGGCTACGATT
ACAGGAGGTCTGACCTGGCAATCATGGCGAATGTGACAACATAGTCACCTCTTGTTAAAATATT
CAGCAGCTTGATGCTCAGTTTGTAAGTTGAAAGAAAATATCAGCCGTCCTTCGTAGAAAAGCAC
CCTGTGTTCGTTTTCCTGTGTTGAAGTAGCACAAATATACGCAGAAATAAGGAAGGACATACAC
TTAACTGTAATTATAAAGGTTCACTTAAAAATTAACTGTTACGTAAACTCGAAGGGCCAGTGAA
CCACGTATTTAAAACGTTTGGAGCAATCTAACCATAAGTAATATTAGTATGATGAGAACATTTA
CTTCTTAAATTAATAACAAATTTTGTTTTAAGTACGAGTTTTCTCTTTCCAAAATACAAGGTTT
CAGTAACCGCATGGGAAGCTTAAAGTTTTAAATATATACTCAGTCATTCGTTGTAACACAGATC
TGGGTAAAAATCACCTCCCCCACCAACCTGAGGGAATATTTATTGCAGACTTTTTGTCCAGCAA
TATTAGTGTTTAAGTTGGACGATTGGGTCTTAAAACATTTATTTGTATAAAGAATTATATATAA
ACGTGAAGATTTGTAATTTAATTTACTTACCACATTGGCAGTACTAATTATTTAGAAGTCACAC
TGTAACTTTGCTCAAAGTCAAGGAGGGCCATTAGTGTTAAGCAGTCAGTATTCCACACTTTATG
TGCCTCTGTGTTTGATGTCTGGTGACTACCGTAAGGACCAGGCAAGAAAAAATAAATAAATTTA
TCTGGTTTCCTGAACTCTAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001102557	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI68960	(Get FASTA)	NCBI Sequence Viewer
	EDL90024	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000033959
	ENSRNOP00000033959.3

RefSeq Acc Id:	NP_001102557 ⟸ NM_001109087
- Peptide Label:	precursor
- UniProtKB:	B5DF81 (UniProtKB/TrEMBL), F7FMB1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGALLALCLLVGLLRWGPAGAQQPGEYCHGWVDAQGNYHEGFQCPEDFDTQDATICCGSCALRY CCAAADARLEQGGCTNDRGELEHPGITAQPVYVPFLIVGSIFIAFIILGSLVAIYCCTCLRPKE PSQQPIRFSLRSYQTETLPMILTSTSLRTASRQSSTATSSSSTGGSVRRFSFARAEPNCLVPSS PPPYTTGHTIHLTQPSGFLVSPQYFAYPLQQEPPLPGKSCPDFSSS hide sequence

Ensembl Acc Id:

ENSRNOP00000033959 ⟸ ENSRNOT00000036103

Protein Domains

Shisa N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B5DF81-F1-model_v2	AlphaFold	B5DF81	1-238	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699303

Promoter ID:

EPDNEW_R9828

Type:

single initiation site

Name:

Shisa3_1

Description:

shisa family member 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	42,221,243 - 42,221,303	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1565710	AgrOrtholog
BioCyc Gene	G2FUF-15788	BioCyc
Ensembl Genes	ENSRNOG00000025670	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000036103	ENTREZGENE
	ENSRNOT00000036103.5	UniProtKB/TrEMBL
InterPro	Shisa	UniProtKB/TrEMBL
	Shisa_N	UniProtKB/TrEMBL
KEGG Report	rno:498356	UniProtKB/TrEMBL
NCBI Gene	498356	ENTREZGENE
PANTHER	PROTEIN SHISA-3 HOMOLOG	UniProtKB/TrEMBL
	PTHR31395	UniProtKB/TrEMBL
Pfam	Shisa	UniProtKB/TrEMBL
PhenoGen	Shisa3	PhenoGen
RatGTEx	ENSRNOG00000025670	RatGTEx
UniProt	B5DF81	ENTREZGENE, UniProtKB/TrEMBL
	F7FMB1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-08-07	Shisa3	shisa family member 3	Shisa3	shisa homolog 3 (Xenopus laevis)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-05-02	Shisa3	shisa homolog 3 (Xenopus laevis)	RGD1565710	similar to MGC68837 protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1565710	similar to MGC68837 protein	RGD1565710_predicted	similar to MGC68837 protein (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1565710_predicted	similar to MGC68837 protein (predicted)	LOC498356	similar to MGC68837 protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC498356	similar to MGC68837 protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD