Gle1l1 (GLE1 RNA export mediator like 1) - Rat Genome Database

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Gene: Gle1l1 (GLE1 RNA export mediator like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Gle1l1 (Ensembl: RGD1565693)
Name: GLE1 RNA export mediator like 1 (Ensembl:similar to GLE1-like, RNA export mediator isoform 1)
RGD ID: 1565693
Description: Predicted to be involved in protein transport; INTERACTS WITH ozone.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: AABR07065139.1; LOC500697; mRNA export factor GLE1-like; nucleoporin GLE1-like; RGD1565693; similar to GLE1-like, RNA export mediator; similar to GLE1-like, RNA export mediator isoform 1
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86112,933,127 - 112,935,465 (+)NCBIGRCr8
mRatBN7.26107,202,205 - 107,204,543 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6107,202,400 - 107,204,535 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.06111,570,751 - 111,573,368 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6111,570,784 - 111,572,949 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.06120,851,478 - 120,853,962 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46111,795,394 - 111,797,724 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera6105,017,113 - 105,019,661 (+)NCBICelera
Cytogenetic Map6q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
ozone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Gle1l1
31 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:63
Count of miRNA genes:60
Interacting mature miRNAs:62
Transcripts:ENSRNOT00000016884
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
731173Uae22Urinary albumin excretion QTL 2210.1urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
2290393Uae37Urinary albumin excretion QTL 370.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)665531555140994061Rat
1641904Alcrsp4Alcohol response QTL 4response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)667262953112262953Rat
1300075Glom7Glomerulus QTL 75.60.0000002kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)671201409116201409Rat
1331789Rf37Renal function QTL 373.224kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)672202632115200186Rat
70196BpQTLcluster7Blood pressure QTL cluster 76.82arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)672202632117202632Rat
724536Uae7Urinary albumin excretion QTL 73.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)672202632130729475Rat
1331799Bp211Blood pressure QTL 2113.66407arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)672202632130919985Rat
1581550Pur8Proteinuria QTL 8urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)672227641130729205Rat
1581563Uae33Urinary albumin excretion QTL 33urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)672227641130729205Rat
724524Uae2Urinary albumin excretion QTL 22.70.0005urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)673463459109394713Rat
737827Hcar11Hepatocarcinoma resistance QTL 114.4liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)682523650110548006Rat
738034Anxrr5Anxiety related response QTL 55.9exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)684130881129130881Rat
10054138Gmadr3Adrenal mass QTL 33.680.00045adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)685140138130140138Rat
10054123Srcrt6Stress Responsive Cort QTL 62.50.0043blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)685140138130140138Rat
724513Uae14Urinary albumin excretion QTL 146.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)685311061133478515Rat
1300076Glom8Glomerulus QTL 870.000000009kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)686894788131894788Rat
2303624Vencon5Ventilatory control QTL 54.45respiration trait (VT:0001943)minute ventilation (CMO:0000132)688047916133047916Rat
1331725Bp212Blood pressure QTL 2123.52475arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)693701310128713626Rat
61414Pia3Pristane induced arthritis QTL 34.5joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)694968928137848904Rat
12801411Schws8Schwannoma susceptibility QTL 8nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)694968928139968928Rat
8552796Vie3Viral induced encephalitis QTL 32.6brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)696833997140994061Rat
1358355Srcrt4Stress Responsive Cort QTL 46.39blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)6100364669140994061Rat
2313399Anxrr28Anxiety related response QTL 28aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)6100671796132340886Rat
1331797Bp213Blood pressure QTL 2133.291arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)6104085867128713626Rat
71111Iddm8Insulin dependent diabetes mellitus QTL 81.90.002blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)6105156861140994061Rat
4145118Mcs26Mammary carcinoma susceptibility QTL 260.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)6106752656132339866Rat


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000016884   ⟹   ENSRNOP00000047389
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl6107,202,400 - 107,204,535 (+)Ensembl
RefSeq Acc Id: XM_039113033   ⟹   XP_038968961
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr86112,933,127 - 112,935,465 (+)NCBI
mRatBN7.26107,202,205 - 107,204,543 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038968961 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000047389.4
Reference Protein Sequences
RefSeq Acc Id: XP_038968961   ⟸   XM_039113033
- UniProtKB: F1M6G0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000047389   ⟸   ENSRNOT00000016884

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M6G0-F1-model_v2 AlphaFold F1M6G0 1-698 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-36694 BioCyc
Ensembl Genes ENSRNOG00000012652 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016884.7 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.510 UniProtKB/TrEMBL
InterPro GLE1 UniProtKB/TrEMBL
  GLE1-like_sf UniProtKB/TrEMBL
NCBI Gene 500697 ENTREZGENE
PANTHER NUCLEOPORIN GLE1 UniProtKB/TrEMBL
  PTHR12960 UniProtKB/TrEMBL
Pfam GLE1 UniProtKB/TrEMBL
PhenoGen Gle1l1 PhenoGen
RatGTEx ENSRNOG00000012652 RatGTEx
UniProt F1M6G0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Gle1l1  GLE1 RNA export mediator like 1  RGD1565693  similar to GLE1-like, RNA export mediator isoform 1  Symbol and Name Changed 1299863 APPROVED
2022-06-02 RGD1565693  similar to GLE1-like, RNA export mediator isoform 1  AABR07065139.1    Data merged from RGD:15003391 737654 PROVISIONAL
2019-11-08 AABR07065139.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2008-04-30 RGD1565693  similar to GLE1-like, RNA export mediator isoform 1   RGD1565693_predicted  similar to GLE1-like, RNA export mediator isoform 1 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565693_predicted  similar to GLE1-like, RNA export mediator isoform 1 (predicted)  LOC500697  similar to GLE1-like, RNA export mediator isoform 1  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500697  similar to GLE1-like, RNA export mediator isoform 1      Symbol and Name status set to provisional 70820 PROVISIONAL