Mageb6 (MAGE family member B6) - Rat Genome Database

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Gene: Mageb6 (MAGE family member B6) Rattus norvegicus
Analyze
Symbol: Mageb6 (Ensembl: Mageb6l1)
Name: MAGE family member B6 (Ensembl:MAGE family member B6 like 1)
RGD ID: 1565662
Description: Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human MAGEB6 (MAGE family member B6); INTERACTS WITH actinomycin D (ortholog); aflatoxin B1 (ortholog); benzo[a]pyrene (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC302441; Mageb17; melanoma antigen family B, 17; melanoma antigen family B, 6; melanoma-associated antigen B17-like; RGD1565662; similar to Smage-3 protein
RGD Orthologs
Human
Mouse
Bonobo
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X60,468,437 - 60,469,905 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX60,468,437 - 60,469,905 (-)EnsemblGRCr8
mRatBN7.2X56,493,231 - 56,494,699 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX56,492,713 - 56,494,541 (-)EnsemblmRatBN7.2
Rnor_6.0X60,863,372 - 60,864,521 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX60,863,453 - 60,864,478 (-)Ensemblrn6Rnor6.0
Rnor_5.0X61,448,940 - 61,450,069 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X79,052,623 - 79,053,729 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX56,983,687 - 56,984,836 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.

Genomics

Comparative Map Data
Mageb6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X60,468,437 - 60,469,905 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX60,468,437 - 60,469,905 (-)EnsemblGRCr8
mRatBN7.2X56,493,231 - 56,494,699 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX56,492,713 - 56,494,541 (-)EnsemblmRatBN7.2
Rnor_6.0X60,863,372 - 60,864,521 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX60,863,453 - 60,864,478 (-)Ensemblrn6Rnor6.0
Rnor_5.0X61,448,940 - 61,450,069 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X79,052,623 - 79,053,729 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX56,983,687 - 56,984,836 (-)NCBICelera
Cytogenetic MapXq22NCBI
MAGEB6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X26,192,440 - 26,195,646 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX26,192,440 - 26,195,646 (+)Ensemblhg38GRCh38
GRCh37X26,210,557 - 26,213,763 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X26,120,478 - 26,123,684 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34X25,970,213 - 25,973,420NCBI
CeleraX30,337,984 - 30,341,189 (+)NCBICelera
Cytogenetic MapXp21.3NCBI
HuRefX23,949,213 - 23,952,423 (+)NCBIHuRef
CHM1_1X26,242,215 - 26,245,426 (+)NCBICHM1_1
T2T-CHM13v2.0X25,779,752 - 25,782,962 (+)NCBIT2T-CHM13v2.0
Mageb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X90,375,511 - 90,376,503 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX90,375,296 - 90,376,966 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X91,331,905 - 91,332,897 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX91,331,690 - 91,333,360 (+)Ensemblmm10GRCm38
MGSCv37X88,577,244 - 88,578,236 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X87,584,624 - 87,585,616 (+)NCBIMGSCv36mm8
CeleraX58,967,165 - 58,967,572 (+)NCBICelera
Cytogenetic MapXC2NCBI
cM MapX40.35NCBI
MAGEB6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X27,995,598 - 27,998,712 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X27,998,979 - 28,002,093 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X18,795,462 - 18,796,559 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X26,159,664 - 26,160,761 (+)NCBIPanPan1.1PanPan1.1panPan2
LOC100513448
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X22,170,175 - 22,171,346 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X23,753,221 - 23,756,311 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAGEB6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X24,657,717 - 24,662,435 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX24,635,118 - 24,661,850 (+)NCBIChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236668922,650 - 6,003 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat


Expression

RNA-SEQ Expression

ectoderm
nervous system
reproductive system
sensory system
visual system
1 1 41 1 1

Sequence


Ensembl Acc Id: ENSRNOT00000088653   ⟹   ENSRNOP00000070675
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX56,492,713 - 56,494,541 (-)Ensembl
Rnor_6.0 EnsemblX60,863,453 - 60,864,478 (-)Ensembl
RefSeq Acc Id: NM_001408843   ⟹   NP_001395772
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X60,468,437 - 60,469,905 (-)NCBI
mRatBN7.2X56,493,231 - 56,494,699 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001395772 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL96025 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000095890
Ensembl Acc Id: ENSRNOP00000070675   ⟸   ENSRNOT00000088653
RefSeq Acc Id: NP_001395772   ⟸   NM_001408843
- UniProtKB: A6IPY8 (UniProtKB/TrEMBL)
Protein Domains
MAGE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JYJ2-F1-model_v2 AlphaFold A0A0G2JYJ2 1-319 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565662 AgrOrtholog
BioCyc Gene G2FUF-2293 BioCyc
Ensembl Genes ENSRNOG00000051281 Ensembl, ENTREZGENE
  ENSRNOG00000055102 Ensembl
Ensembl Transcript ENSRNOT00000076333 ENTREZGENE
Gene3D-CATH 1.10.10.1200 UniProtKB/TrEMBL
  1.10.10.1210 UniProtKB/TrEMBL
InterPro MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
  MAGE_WH1 UniProtKB/TrEMBL
  MAGE_WH2 UniProtKB/TrEMBL
  MHD_dom UniProtKB/TrEMBL
NCBI Gene 302441 ENTREZGENE
PANTHER MELANOMA-ASSOCIATED ANTIGEN B6B UniProtKB/TrEMBL
  PTHR11736 UniProtKB/TrEMBL
Pfam MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
PhenoGen Mageb6 PhenoGen
PROSITE MAGE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000051281 RatGTEx
  ENSRNOG00000055102 RatGTEx
SMART MAGE UniProtKB/TrEMBL
  MAGE_N UniProtKB/TrEMBL
UniProt A6IPY8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-04-19 Mageb6  MAGE family member B6  Mageb6  melanoma antigen family B, 6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-05 Mageb6  melanoma antigen family B, 6  Mageb17  melanoma antigen family B, 17  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-06-12 Mageb17  melanoma antigen family B, 17  RGD1565662  similar to Smage-3 protein   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1565662  similar to Smage-3 protein   RGD1565662_predicted  similar to Smage-3 protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565662_predicted  similar to Smage-3 protein (predicted)  LOC302441  similar to Smage-3 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC302441  similar to Smage-3 protein      Symbol and Name status set to provisional 70820 PROVISIONAL