Ranbp1l1 (RAN binding protein 1 like 1) - Rat Genome Database

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Gene: Ranbp1l1 (RAN binding protein 1 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Ranbp1l1
Name: RAN binding protein 1 like 1
RGD ID: 1565297
Description: Predicted to enable GTPase activator activity. Predicted to be involved in nuclear export. Predicted to be located in cytoplasm. Predicted to be part of nuclear pore. Orthologous to human RANBP1 (RAN binding protein 1); INTERACTS WITH 17beta-estradiol; bisphenol A.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: AABR07034362.1; LOC498088; ran-specific GTPase-activating protein-like; RGD1565297; similar to hypothetical protein A
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81178,151,852 - 78,152,721 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1178,151,415 - 78,157,309 (+)EnsemblGRCr8
mRatBN7.21164,646,634 - 64,647,446 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1164,646,726 - 64,647,337 (+)EnsemblmRatBN7.2
Rnor_6.01167,584,224 - 67,585,500 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1167,584,435 - 67,585,043 (+)NCBIrn6Rnor6.0
Rnor_5.01170,671,713 - 70,672,754 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41166,482,490 - 66,483,210 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1164,114,734 - 64,116,010 (+)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
nuclear pore  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Ranbp1l1
3 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)117330848796070872Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)114644316891443168Rat
1598811Bp291Blood pressure QTL 2911.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113330600878306008Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)113294306789836615Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)113642841681428416Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)115893182292356038Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)113461876079618760Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)115775483796071021Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112019354996351019Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)115107102196071021Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)112252474682951192Rat
1598841Memor7Memory QTL 7exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)113330600878306008Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)115827236396350770Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)113674945981749459Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)115441539196071021Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)113674945981749459Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116859932196497754Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)113674945981749459Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
sensory system
visual system
6 13 11 21 11 20 4 13 9 9

Sequence


Ensembl Acc Id: ENSRNOT00000038162   ⟹   ENSRNOP00000097785
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1178,151,415 - 78,157,309 (+)Ensembl
mRatBN7.2 Ensembl1164,646,726 - 64,647,337 (+)Ensembl
RefSeq Acc Id: XM_039088912   ⟹   XP_038944840
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81178,151,852 - 78,152,721 (+)NCBI
mRatBN7.21164,646,634 - 64,647,446 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038944840 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000081797.2
  ENSRNOP00000097785
  ENSRNOP00000097785.1
RefSeq Acc Id: XP_038944840   ⟸   XM_039088912
- UniProtKB: A0A8I6ATA7 (UniProtKB/TrEMBL),   A0A8I5ZTU5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000097785   ⟸   ENSRNOT00000038162
Protein Domains
RanBD1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565297 AgrOrtholog
BioCyc Gene G2FUF-21213 BioCyc
Ensembl Genes ENSRNOG00000001884 UniProtKB/TrEMBL
  ENSRNOG00000023917 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038162 ENTREZGENE
  ENSRNOT00000038162.6 UniProtKB/TrEMBL
  ENSRNOT00000094129.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  Ran_bind_dom UniProtKB/TrEMBL
  RanBP1-like UniProtKB/TrEMBL
  RanBP1_RanBD UniProtKB/TrEMBL
NCBI Gene 498088 ENTREZGENE
PANTHER PTHR23138 UniProtKB/TrEMBL
  RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN UniProtKB/TrEMBL
Pfam Ran_BP1 UniProtKB/TrEMBL
PhenoGen Ranbp1l1 PhenoGen
PROSITE RANBD1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001884 RatGTEx
  ENSRNOG00000023917 RatGTEx
SMART RanBD UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt A0A8I5ZTU5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ATA7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Ranbp1l1  RAN binding protein 1 like 1  RGD1565297  similar to hypothetical protein A  Symbol and Name Changed 1299863 APPROVED
2022-06-02 RGD1565297  similar to hypothetical protein A  AABR07034362.1    Data merged from RGD:15003575 737654 PROVISIONAL
2019-11-08 AABR07034362.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2008-04-30 RGD1565297  similar to hypothetical protein A   RGD1565297_predicted  similar to hypothetical protein A (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565297_predicted  similar to hypothetical protein A (predicted)  LOC498088  similar to hypothetical protein A  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498088  similar to hypothetical protein A      Symbol and Name status set to provisional 70820 PROVISIONAL