Klhl3 (kelch-like family member 3) - Rat Genome Database

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Pathways
Gene: Klhl3 (kelch-like family member 3) Rattus norvegicus
Analyze
Symbol: Klhl3
Name: kelch-like family member 3
RGD ID: 1565218
Description: Predicted to enable cullin family protein binding activity and ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in several processes, including potassium ion homeostasis; protein K48-linked ubiquitination; and renal sodium ion absorption. Predicted to be located in cytoskeleton. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in pseudohypoaldosteronism. Orthologous to human KLHL3 (kelch like family member 3); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: kelch-like 3; kelch-like 3 (Drosophila); kelch-like protein 3; kelch-like protein 3-like; LOC102549506; LOC498697; RGD1565218; similar to Kelch-like protein 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8176,528,114 - 6,651,338 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl176,528,487 - 6,651,338 (+)EnsemblGRCr8
mRatBN7.2176,523,089 - 6,645,971 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,521,912 - 6,642,154 (+)EnsemblmRatBN7.2
Rnor_6.0176,924,423 - 7,029,374 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl176,935,860 - 7,029,240 (+)Ensemblrn6Rnor6.0
Rnor_5.0179,127,119 - 9,226,548 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41712,467,372 - 12,615,579 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera176,642,858 - 6,746,645 (+)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
Cul3-RING ubiquitin ligase complex  (IBA,IEA,ISO,ISS)
cytoplasm  (IBA)
cytoskeleton  (IEA)
cytosol  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14528312   PMID:22406640   PMID:23453970   PMID:23576762   PMID:28315668  


Genomics

Comparative Map Data
Klhl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8176,528,114 - 6,651,338 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl176,528,487 - 6,651,338 (+)EnsemblGRCr8
mRatBN7.2176,523,089 - 6,645,971 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,521,912 - 6,642,154 (+)EnsemblmRatBN7.2
Rnor_6.0176,924,423 - 7,029,374 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl176,935,860 - 7,029,240 (+)Ensemblrn6Rnor6.0
Rnor_5.0179,127,119 - 9,226,548 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41712,467,372 - 12,615,579 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera176,642,858 - 6,746,645 (+)NCBICelera
Cytogenetic Map17p14NCBI
KLHL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385137,617,500 - 137,736,089 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5137,617,500 - 137,736,221 (-)Ensemblhg38GRCh38
GRCh375136,953,189 - 137,071,778 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365136,981,088 - 137,099,362 (-)NCBIBuild 36Build 36hg18NCBI36
Build 345136,981,087 - 137,099,362NCBI
Celera5133,075,978 - 133,193,214 (-)NCBICelera
Cytogenetic Map5q31.2NCBI
HuRef5132,139,787 - 132,262,439 (-)NCBIHuRef
CHM1_15136,384,126 - 136,504,377 (-)NCBICHM1_1
T2T-CHM13v2.05138,138,636 - 138,261,929 (-)NCBIT2T-CHM13v2.0
Klhl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391358,148,040 - 58,271,288 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1358,148,042 - 58,261,406 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381358,000,226 - 58,123,477 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1358,000,228 - 58,113,592 (-)Ensemblmm10GRCm38
MGSCv371358,106,318 - 58,203,789 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera1359,066,981 - 59,164,682 (-)NCBICelera
Cytogenetic Map13B1NCBI
cM Map1330.92NCBI
Klhl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540832,596,497 - 32,721,059 (-)Ensembl
ChiLan1.0NW_00495540832,596,497 - 32,719,967 (-)NCBIChiLan1.0ChiLan1.0
KLHL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24132,901,119 - 133,171,625 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15131,040,673 - 131,310,411 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05133,005,563 - 133,276,087 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15139,143,206 - 139,260,023 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5139,147,793 - 139,248,919 (-)EnsemblpanPan2panpan1.1
KLHL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11125,329,922 - 25,505,281 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1125,334,241 - 25,443,494 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1124,086,955 - 24,200,948 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01126,173,569 - 26,287,102 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1126,173,583 - 26,444,143 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11124,881,486 - 24,994,505 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01124,705,374 - 24,818,153 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01125,366,972 - 25,480,990 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Klhl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213125,567,720 - 125,671,453 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365974,592,621 - 4,696,377 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365974,592,654 - 4,696,348 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLHL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2139,632,869 - 139,920,497 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12139,632,868 - 139,890,079 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22145,353,783 - 145,611,841 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KLHL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12340,301,406 - 40,419,927 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2340,301,414 - 40,417,839 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603437,474,064 - 37,591,313 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Klhl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247339,299,229 - 9,413,469 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247339,299,217 - 9,413,390 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Klhl3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11479,999,429 - 80,115,537 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Klhl3
956 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:120
Count of miRNA genes:94
Interacting mature miRNAs:102
Transcripts:ENSRNOT00000034877
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17136045694Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17143999106Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17436005727233623Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17121499218Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17212084342054133Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17473353449733534Rat
2302377Scl61Serum cholesterol level QTL 614.36blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)17622199858177198Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138037084Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131706603Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17473353449733534Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17143999106Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17436005727233623Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17143999106Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17212084322087569Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)17122181410Rat
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122877318Rat

Markers in Region
RH79130  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,509,140 - 6,509,273 (+)MAPPERmRatBN7.2
Rnor_6.0176,910,901 - 6,911,033NCBIRnor6.0
Rnor_5.0179,113,542 - 9,113,674UniSTSRnor5.0
RGSC_v3.41712,453,164 - 12,453,296UniSTSRGSC3.4
Celera176,618,347 - 6,618,479UniSTS
Cytogenetic Map17p14UniSTS
RH127764  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,509,984 - 6,510,186 (+)MAPPERmRatBN7.2
Rnor_6.0176,911,745 - 6,911,946NCBIRnor6.0
Rnor_5.0179,114,386 - 9,114,587UniSTSRnor5.0
RGSC_v3.41712,454,008 - 12,454,209UniSTSRGSC3.4
Celera176,619,191 - 6,619,392UniSTS
RH 3.4 Map1767.3UniSTS
Cytogenetic Map17p14UniSTS
BF386148  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,534,435 - 6,534,630 (+)MAPPERmRatBN7.2
Rnor_6.0176,936,141 - 6,936,335NCBIRnor6.0
Rnor_5.0179,138,837 - 9,139,031UniSTSRnor5.0
RGSC_v3.41712,478,599 - 12,478,793UniSTSRGSC3.4
Celera176,643,412 - 6,643,606UniSTS
RH 3.4 Map1769.9UniSTS
Cytogenetic Map17p14UniSTS
AA858784  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,509,091 - 6,509,241 (+)MAPPERmRatBN7.2
Rnor_6.0176,910,852 - 6,911,001NCBIRnor6.0
Rnor_5.0179,113,493 - 9,113,642UniSTSRnor5.0
RGSC_v3.41712,453,115 - 12,453,264UniSTSRGSC3.4
Celera176,618,298 - 6,618,447UniSTS
RH 3.4 Map1771.6UniSTS
Cytogenetic Map17p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000034877   ⟹   ENSRNOP00000037981
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl176,544,770 - 6,640,042 (+)Ensembl
mRatBN7.2 Ensembl176,539,375 - 6,634,716 (+)Ensembl
Rnor_6.0 Ensembl176,935,860 - 7,029,240 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000090380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl177,602,304 - 7,619,181 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118353   ⟹   ENSRNOP00000086341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl176,521,912 - 6,642,154 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119182   ⟹   ENSRNOP00000081756
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl176,528,487 - 6,651,338 (+)Ensembl
mRatBN7.2 Ensembl176,522,693 - 6,642,154 (+)Ensembl
RefSeq Acc Id: NM_001419643   ⟹   NP_001406572
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8176,528,487 - 6,651,338 (+)NCBI
mRatBN7.2176,523,089 - 6,645,959 (+)NCBI
RefSeq Acc Id: XM_039096443   ⟹   XP_038952371
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8176,528,114 - 6,651,338 (+)NCBI
mRatBN7.2176,523,094 - 6,645,971 (+)NCBI
RefSeq Acc Id: XM_039096444   ⟹   XP_038952372
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8176,580,127 - 6,651,338 (+)NCBI
mRatBN7.2176,574,738 - 6,645,971 (+)NCBI
RefSeq Acc Id: XM_039096445   ⟹   XP_038952373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8176,615,550 - 6,651,338 (+)NCBI
mRatBN7.2176,610,191 - 6,645,971 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001406572 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952371 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952372 (Get FASTA)   NCBI Sequence Viewer  
  XP_038952373 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL93924 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000081756
GenBank Protein F1LZ52 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Acc Id: ENSRNOP00000037981   ⟸   ENSRNOT00000034877
RefSeq Acc Id: XP_038952371   ⟸   XM_039096443
- Peptide Label: isoform X1
- UniProtKB: A0A8I6G8D9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038952372   ⟸   XM_039096444
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038952373   ⟸   XM_039096445
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000081756   ⟸   ENSRNOT00000119182
Ensembl Acc Id: ENSRNOP00000086341   ⟸   ENSRNOT00000118353
RefSeq Acc Id: NP_001406572   ⟸   NM_001419643
Protein Domains
BACK   BTB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LZ52-F1-model_v2 AlphaFold F1LZ52 1-587 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565218 AgrOrtholog
BioCyc Gene G2FUF-10329 BioCyc
Ensembl Genes ENSRNOG00000019533 Ensembl, ENTREZGENE
  ENSRNOG00000053948 Ensembl
Ensembl Transcript ENSRNOT00000119182 ENTREZGENE
Gene3D-CATH 1.25.40.420 UniProtKB/Swiss-Prot
  2.120.10.80 UniProtKB/Swiss-Prot
  Potassium Channel Kv1.1, Chain A UniProtKB/Swiss-Prot
InterPro BACK UniProtKB/Swiss-Prot
  BTB-kelch_protein UniProtKB/Swiss-Prot
  BTB/POZ_dom UniProtKB/Swiss-Prot
  Kelch-typ_b-propeller UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
  KLHL3 UniProtKB/Swiss-Prot
  SKP1/BTB/POZ_sf UniProtKB/Swiss-Prot
NCBI Gene 498697 ENTREZGENE
PANTHER KELCH PROTEIN UniProtKB/Swiss-Prot
  PTHR24412:SF179 UniProtKB/Swiss-Prot
Pfam BACK UniProtKB/Swiss-Prot
  BTB UniProtKB/Swiss-Prot
  Kelch_1 UniProtKB/Swiss-Prot
PhenoGen Klhl3 PhenoGen
PIRSF Kelch-like_protein_gigaxonin UniProtKB/Swiss-Prot
PRINTS KELCHREPEAT UniProtKB/Swiss-Prot
PROSITE BTB UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000019533 RatGTEx
  ENSRNOG00000053948 RatGTEx
SMART BACK UniProtKB/Swiss-Prot
  BTB UniProtKB/Swiss-Prot
  Kelch UniProtKB/Swiss-Prot
Superfamily-SCOP SSF117281 UniProtKB/Swiss-Prot
  SSF54695 UniProtKB/Swiss-Prot
UniProt A0A8I6G8D9 ENTREZGENE, UniProtKB/TrEMBL
  F1LZ52 ENTREZGENE
  J3KTS0_RAT UniProtKB/TrEMBL
  KLHL3_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Klhl3  kelch-like family member 3  LOC102549506  kelch-like protein 3-like  Data merged from RGD:7622474 737654 PROVISIONAL
2013-12-18 LOC102549506  kelch-like protein 3-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-02-06 Klhl3  kelch-like family member 3  Klhl3  kelch-like 3 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 Klhl3  kelch-like 3 (Drosophila)  RGD1565218  similar to Kelch-like protein 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1565218  similar to Kelch-like protein 3   RGD1565218_predicted  similar to Kelch-like protein 3 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565218_predicted  similar to Kelch-like protein 3 (predicted)  LOC498697  similar to Kelch-like protein 3  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498697  similar to Kelch-like protein 3      Symbol and Name status set to provisional 70820 PROVISIONAL