Fgd1 (FYVE, RhoGEF and PH domain containing 1) - Rat Genome Database

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Gene: Fgd1 (FYVE, RhoGEF and PH domain containing 1) Rattus norvegicus
Analyze
Symbol: Fgd1
Name: FYVE, RhoGEF and PH domain containing 1
RGD ID: 1565188
Description: Predicted to enable guanyl-nucleotide exchange factor activity and small GTPase binding activity. Predicted to be involved in actin cytoskeleton organization; filopodium assembly; and regulation of cell shape. Predicted to be located in Golgi apparatus; lamellipodium; and ruffle. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in X-linked Aarskog syndrome and non-syndromic X-linked intellectual disability. Orthologous to human FGD1 (FYVE, RhoGEF and PH domain containing 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; furan; gentamycin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: FYVE, RhoGEF and PH domain-containing protein 1; FYVE, RhoGEF and PH domain-containing protein 1-like; LOC102555067; LOC108348117
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X23,466,791 - 23,509,773 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX23,467,530 - 23,509,979 (+)EnsemblGRCr8
mRatBN7.2X20,023,746 - 20,066,734 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX20,023,746 - 20,066,566 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX17,462,039 - 17,504,869 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X22,618,713 - 22,661,545 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X20,552,995 - 20,595,814 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X20,100,942 - 20,143,871 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX20,100,942 - 20,143,871 (+)Ensemblrn6Rnor6.0
Rnor_6.0 EnsemblX20,216,587 - 20,225,955 (+)Ensemblrn6Rnor6.0
Rnor_5.0X20,846,380 - 20,888,661 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X40,364,211 - 40,407,213 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX20,281,249 - 20,323,819 (+)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,IEA,ISO)
cytoskeleton  (IEA)
cytosol  (IEA,ISO)
Golgi apparatus  (IEA,ISO)
lamellipodium  (IEA,ISO)
plasma membrane  (IEA,ISO)
ruffle  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Novel FGD1 mutation underlying Aarskog-Scott syndrome with myopathy and distal arthropathy. Al-Semari A, etal., Clin Dysmorphol. 2013 Jan;22(1):13-7. doi: 10.1097/MCD.0b013e32835b6dc4.
2. Faciogenital dysplasia protein Fgd1 regulates invadopodia biogenesis and extracellular matrix degradation and is up-regulated in prostate and breast cancer. Ayala I, etal., Cancer Res. 2009 Feb 1;69(3):747-52. doi: 10.1158/0008-5472.CAN-08-1980. Epub 2009 Jan 13.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Non-syndromic X-linked mental retardation associated with a missense mutation (P312L) in the FGD1 gene. Lebel RR, etal., Clin Genet. 2002 Feb;61(2):139-45.
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. Aarskog-Scott syndrome: clinical update and report of nine novel mutations of the FGD1 gene. Orrico A, etal., Am J Med Genet A. 2010 Feb;152A(2):313-8. doi: 10.1002/ajmg.a.33199.
7. Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor. Pasteris NG, etal., Cell. 1994 Nov 18;79(4):669-78.
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Comprehensive gene review and curation RGD comprehensive gene curation
12. Clinical variation of Aarskog syndrome in a large family with 2189delA in the FGD1 gene. Shalev SA, etal., Am J Med Genet A. 2006 Jan 15;140(2):162-5.
13. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:8969170   PMID:12913069  


Genomics

Comparative Map Data
Fgd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X23,466,791 - 23,509,773 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX23,467,530 - 23,509,979 (+)EnsemblGRCr8
mRatBN7.2X20,023,746 - 20,066,734 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX20,023,746 - 20,066,566 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX17,462,039 - 17,504,869 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X22,618,713 - 22,661,545 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X20,552,995 - 20,595,814 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X20,100,942 - 20,143,871 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX20,100,942 - 20,143,871 (+)Ensemblrn6Rnor6.0
Rnor_6.0 EnsemblX20,216,587 - 20,225,955 (+)Ensemblrn6Rnor6.0
Rnor_5.0X20,846,380 - 20,888,661 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X40,364,211 - 40,407,213 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX20,281,249 - 20,323,819 (+)NCBICelera
Cytogenetic MapXq12NCBI
FGD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X54,445,454 - 54,496,234 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX54,445,454 - 54,496,234 (-)Ensemblhg38GRCh38
GRCh37X54,471,887 - 54,522,667 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X54,488,612 - 54,539,324 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34X54,354,909 - 54,405,620NCBI
CeleraX58,304,448 - 58,355,160 (-)NCBICelera
Cytogenetic MapXp11.22NCBI
HuRefX51,522,464 - 51,572,796 (-)NCBIHuRef
CHM1_1X54,462,541 - 54,513,238 (-)NCBICHM1_1
T2T-CHM13v2.0X53,736,310 - 53,787,092 (-)NCBIT2T-CHM13v2.0
Fgd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X149,829,141 - 149,872,682 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX149,829,146 - 149,872,517 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X151,046,141 - 151,089,686 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX151,046,150 - 151,089,521 (+)Ensemblmm10GRCm38
MGSCv37X147,481,776 - 147,523,642 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X146,387,949 - 146,429,815 (+)NCBIMGSCv36mm8
MGSCv36X128,052,708 - 128,094,514 (+)NCBIMGSCv36mm8
CeleraX133,315,143 - 133,357,665 (-)NCBICelera
Cytogenetic MapXF3NCBI
cM MapX68.46NCBI
Fgd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554751,703,374 - 1,752,710 (-)Ensembl
ChiLan1.0NW_0049554751,703,374 - 1,752,710 (-)NCBIChiLan1.0ChiLan1.0
FGD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X55,834,119 - 55,884,005 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X55,837,723 - 55,887,601 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X46,648,765 - 46,699,444 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X54,880,751 - 54,930,672 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX54,880,513 - 54,930,672 (-)EnsemblpanPan2panpan1.1
FGD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X46,194,950 - 46,239,291 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX46,194,735 - 46,270,701 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX37,583,900 - 37,627,968 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X46,516,320 - 46,560,389 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX46,516,275 - 46,560,769 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X46,014,132 - 46,058,399 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X46,464,507 - 46,508,560 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X46,531,810 - 46,575,872 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Fgd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X39,012,340 - 39,057,557 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367511,351,795 - 1,397,288 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367511,355,606 - 1,397,282 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX47,192,427 - 47,231,342 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X47,191,838 - 47,231,656 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X53,049,149 - 53,088,229 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X50,554,648 - 50,609,437 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX50,556,168 - 50,583,010 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660864,520,644 - 4,572,317 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fgd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249092,316,431 - 2,370,179 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249092,316,749 - 2,370,097 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Fgd1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X30,187,095 - 30,228,679 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Fgd1
188 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:673
Count of miRNA genes:216
Interacting mature miRNAs:259
Transcripts:ENSRNOT00000003443, ENSRNOT00000073114
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X400149344939387Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X197044046970440Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X811148653111486Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X400149324470521Rat

Markers in Region
RH128051  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X20,066,600 - 20,066,789 (+)MAPPERmRatBN7.2
Rnor_6.0X20,143,904 - 20,144,092NCBIRnor6.0
Rnor_6.0X20,226,617 - 20,226,805NCBIRnor6.0
Rnor_5.0X20,971,407 - 20,971,595UniSTSRnor5.0
Rnor_5.0X20,888,694 - 20,888,882UniSTSRnor5.0
RGSC_v3.4X40,407,246 - 40,407,434UniSTSRGSC3.4
CeleraX20,323,852 - 20,324,040UniSTS
RH 3.4 MapX211.43UniSTS
Cytogenetic MapXq21UniSTS
RH136927  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X20,064,191 - 20,064,397 (+)MAPPERmRatBN7.2
Rnor_6.0X20,141,495 - 20,141,700NCBIRnor6.0
Rnor_6.0X20,224,208 - 20,224,413NCBIRnor6.0
Rnor_5.0X20,886,285 - 20,886,490UniSTSRnor5.0
Rnor_5.0X20,968,998 - 20,969,203UniSTSRnor5.0
RGSC_v3.4X40,404,837 - 40,405,042UniSTSRGSC3.4
CeleraX20,321,443 - 20,321,648UniSTS
Cytogenetic MapXq21UniSTS
Fgd1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X20,065,744 - 20,065,911 (+)MAPPERmRatBN7.2
Rnor_6.0X20,225,761 - 20,225,927NCBIRnor6.0
Rnor_6.0X20,143,048 - 20,143,214NCBIRnor6.0
Rnor_5.0X20,887,838 - 20,888,004UniSTSRnor5.0
Rnor_5.0X20,970,551 - 20,970,717UniSTSRnor5.0
RGSC_v3.4X40,406,390 - 40,406,556UniSTSRGSC3.4
CeleraX20,322,996 - 20,323,162UniSTS
Cytogenetic MapXq21UniSTS
MARC_5967-5968:997299492:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X20,063,123 - 20,063,615 (+)MAPPERmRatBN7.2
Rnor_6.0X20,223,140 - 20,223,631NCBIRnor6.0
Rnor_6.0X20,140,427 - 20,140,918NCBIRnor6.0
Rnor_5.0X20,885,217 - 20,885,708UniSTSRnor5.0
Rnor_5.0X20,967,930 - 20,968,421UniSTSRnor5.0
RGSC_v3.4X40,403,769 - 40,404,260UniSTSRGSC3.4
CeleraX20,320,375 - 20,320,866UniSTS
Cytogenetic MapXq21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
22 12 73 191 125 120 77 71 77 12 387 189 10 158 91 111 43 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000003443
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX20,100,942 - 20,143,869 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000073114   ⟹   ENSRNOP00000065109
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX20,216,587 - 20,225,955 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093505
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX23,467,530 - 23,509,979 (+)Ensembl
mRatBN7.2 EnsemblX20,023,746 - 20,066,566 (+)Ensembl
Rnor_6.0 EnsemblX20,100,942 - 20,143,871 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093576
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX23,467,530 - 23,509,773 (+)Ensembl
mRatBN7.2 EnsemblX20,024,452 - 20,066,566 (+)Ensembl
Rnor_6.0 EnsemblX20,101,963 - 20,143,420 (+)Ensembl
RefSeq Acc Id: NM_001037546   ⟹   NP_001032635
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,466,791 - 23,509,607 (+)NCBI
mRatBN7.2X20,023,746 - 20,066,568 (+)NCBI
Rnor_6.0X20,100,942 - 20,143,871 (+)NCBI
Rnor_5.0X20,846,380 - 20,888,661 (+)NCBI
RGSC_v3.4X40,364,211 - 40,407,213 (+)RGD
CeleraX20,281,249 - 20,323,819 (+)RGD
Sequence:
RefSeq Acc Id: NM_001414732   ⟹   NP_001401661
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,467,530 - 23,509,773 (+)NCBI
mRatBN7.2X20,024,485 - 20,066,734 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001032635 (Get FASTA)   NCBI Sequence Viewer  
  NP_001401661 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI10052 (Get FASTA)   NCBI Sequence Viewer  
  EDL86323 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000079256
  ENSRNOP00000079256.1
  ENSRNOP00000089219.2
RefSeq Acc Id: NP_001032635   ⟸   NM_001037546
- Peptide Label: isoform 2
- UniProtKB: Q2YDU5 (UniProtKB/TrEMBL),   A6KL97 (UniProtKB/TrEMBL),   A0A8I6AC87 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000065109   ⟸   ENSRNOT00000073114
RefSeq Acc Id: NP_001401661   ⟸   NM_001414732
- Peptide Label: isoform 1
- UniProtKB: A0A8I5ZMG2 (UniProtKB/TrEMBL)
Protein Domains
DH   FYVE-type   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R6Q4-F1-model_v2 AlphaFold M0R6Q4 1-396 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565188 AgrOrtholog
BioCyc Gene G2FUF-2779 BioCyc
Ensembl Genes ENSRNOG00000038970 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000047165 Ensembl
Ensembl Transcript ENSRNOT00000093505.3 UniProtKB/TrEMBL
  ENSRNOT00000093576 ENTREZGENE
  ENSRNOT00000093576.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7459258 IMAGE-MGC_LOAD
InterPro DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  FGD1-4_PH2 UniProtKB/TrEMBL
  FGD1_PH1 UniProtKB/TrEMBL
  FYVE_RhoGEF_PH UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Znf_FYVE UniProtKB/TrEMBL
  Znf_FYVE-rel UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
MGC_CLONE MGC:125256 IMAGE-MGC_LOAD
NCBI Gene 363460 ENTREZGENE
PANTHER FACIOGENITAL DYSPLASIA PROTEIN UniProtKB/TrEMBL
  FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam FYVE UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
PhenoGen Fgd1 PhenoGen
PRINTS PRICHEXTENSN UniProtKB/TrEMBL
PROSITE DH_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  ZF_FYVE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000038970 RatGTEx
  ENSRNOG00000047165 RatGTEx
SMART FYVE UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP DH-domain UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
UniProt A0A8I5ZMG2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AC87 ENTREZGENE, UniProtKB/TrEMBL
  A0ABZ3NNG2_RAT UniProtKB/TrEMBL
  A6KL97 ENTREZGENE, UniProtKB/TrEMBL
  Q2YDU5 ENTREZGENE
UniProt Secondary Q2YDU5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Fgd1  FYVE, RhoGEF and PH domain containing 1  LOC108348117  FYVE, RhoGEF and PH domain-containing protein 1-like  Data merged from RGD:11359093 737654 PROVISIONAL
2016-08-02 LOC108348117  FYVE, RhoGEF and PH domain-containing protein 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2015-07-29 Fgd1  FYVE, RhoGEF and PH domain containing 1  LOC102555067  FYVE, RhoGEF and PH domain-containing protein 1-like  Data merged from RGD:7741778 737654 PROVISIONAL
2013-12-18 LOC102555067  FYVE, RhoGEF and PH domain-containing protein 1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-30 Fgd1  FYVE, RhoGEF and PH domain containing 1      Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 Fgd1  FYVE, RhoGEF and PH domain containing 1      Symbol and Name status set to provisional 70820 PROVISIONAL