Rpl23al4 (ribosomal protein L23A like 4) - Rat Genome Database

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Gene: Rpl23al4 (ribosomal protein L23A like 4) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rpl23al4 (Ensembl: Rpl23a)
Name: ribosomal protein L23A like 4 (Ensembl:ribosomal protein L23A)
RGD ID: 1565170
Description: Predicted to be a structural constituent of ribosome. Predicted to be part of cytosolic large ribosomal subunit; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; Cuprizon.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 60S ribosomal protein L23a-like; AABR07018050.1; large ribosomal subunit protein uL23-like; LOC498523; RGD1565170; ribosomal protein L23A like 1; Rpl23al1; similar to 60S ribosomal protein L23a
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81535,417,549 - 35,418,550 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1535,417,915 - 35,418,565 (+)EnsemblGRCr8
mRatBN7.21531,302,164 - 31,302,986 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1531,302,329 - 31,302,979 (+)EnsemblmRatBN7.2
Rnor_6.01537,418,873 - 37,419,536 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1537,418,885 - 37,419,358 (+)NCBIrn6Rnor6.0
Rnor_5.01541,266,064 - 41,267,839 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41536,195,512 - 36,196,006 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1531,014,437 - 31,015,100 (+)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
translation  (IEA)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Rpl23al4
1 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:24
Count of miRNA genes:24
Interacting mature miRNAs:24
Transcripts:ENSRNOT00000043836
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15231575947315759Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15139411584Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15144836456Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15231575953331089Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)153185580392671517Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152272835342072050Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152852773273527732Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1525285835104695021Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152233635152597086Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1525285835104695021Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151915576287086765Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15278592347785923Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151492659471614418Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152233635167336351Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1525285835104695021Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
5 1 9 7 18 8 1 11 5 3 5 5

Sequence


Ensembl Acc Id: ENSRNOT00000043836   ⟹   ENSRNOP00000044111
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1535,417,915 - 35,418,565 (+)Ensembl
mRatBN7.2 Ensembl1531,302,329 - 31,302,979 (+)Ensembl
RefSeq Acc Id: XM_063274867   ⟹   XP_063130937
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81535,417,549 - 35,418,550 (+)NCBI
Protein Sequences
Protein RefSeqs XP_063130937 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000044111
  ENSRNOP00000044111.4
Ensembl Acc Id: ENSRNOP00000044111   ⟸   ENSRNOT00000043836
RefSeq Acc Id: XP_063130937   ⟸   XM_063274867
- UniProtKB: D3ZTX9 (UniProtKB/TrEMBL)
Protein Domains
Large ribosomal subunit protein uL23 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZTX9-F1-model_v2 AlphaFold D3ZTX9 1-158 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565170 AgrOrtholog
BioCyc Gene G2FUF-13607 BioCyc
Ensembl Genes ENSRNOG00000032148 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000043836 ENTREZGENE
  ENSRNOT00000043836.5 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  Ribosomal_uL23-like UniProtKB/TrEMBL
  Ribosomal_uL23/eL15/eS24_sf UniProtKB/TrEMBL
  Ribosomal_uL23_N UniProtKB/TrEMBL
NCBI Gene 498523 ENTREZGENE
PANTHER 60S RIBOSOMAL PROTEIN L23A UniProtKB/TrEMBL
Pfam Ribosomal_L23 UniProtKB/TrEMBL
  Ribosomal_L23eN UniProtKB/TrEMBL
PhenoGen Rpl23al4 PhenoGen
RatGTEx ENSRNOG00000032148 RatGTEx
Superfamily-SCOP Ribosomal proteins S24e, L23 and L15e UniProtKB/TrEMBL
UniProt D3ZTX9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-10-13 Rpl23al4  ribosomal protein L23A like 4  Rpl23al1  ribosomal protein L23A like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2023-09-19 Rpl23al1  ribosomal protein L23A like 1  RGD1565170  similar to 60S ribosomal protein L23a  Symbol and Name Changed 1299863 APPROVED
2022-06-02 RGD1565170  similar to 60S ribosomal protein L23a  AABR07018050.1    Data merged from RGD:15003935 737654 PROVISIONAL
2019-11-08 AABR07018050.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2008-04-30 RGD1565170  similar to 60S ribosomal protein L23a   RGD1565170_predicted  similar to 60S ribosomal protein L23a (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1565170_predicted  similar to 60S ribosomal protein L23a (predicted)  LOC498523  similar to 60S ribosomal protein L23a  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498523  similar to 60S ribosomal protein L23a      Symbol and Name status set to provisional 70820 PROVISIONAL