Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Pwwp3b | Rat | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of PWWP3B mRNA and [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of MUM1L1 mRNA | CTD | PMID:26496021 and PMID:32741896 | Pwwp3b | Rat | 17beta-estradiol | multiple interactions | ISO | PWWP3B (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of PWWP3B mRNA | CTD | PMID:30165855 | Pwwp3b | Rat | 17beta-estradiol 3-benzoate | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of MUM1L1 mRNA | CTD | PMID:32741896 | Pwwp3b | Rat | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of MUM1L1 mRNA | CTD | PMID:29581250 | Pwwp3b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PWWP3B mRNA | CTD | PMID:20106945 | Pwwp3b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MUM1L1 mRNA | CTD | PMID:33387578 | Pwwp3b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Pwwp3b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of PWWP3B mRNA | CTD | PMID:19770486 | Pwwp3b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Pwwp3b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PWWP3B mRNA | CTD | PMID:24680724 | Pwwp3b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of PWWP3B mRNA | CTD | PMID:22298810 | Pwwp3b | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Pwwp3b (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:38648751 | Pwwp3b | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of PWWP3B mRNA | CTD | PMID:24780913 | Pwwp3b | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of PWWP3B mRNA | CTD | PMID:28959563 | Pwwp3b | Rat | acrylamide | increases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | Acrylamide results in increased expression of PWWP3B mRNA | CTD | PMID:32763439 | Pwwp3b | Rat | afimoxifene | multiple interactions | ISO | PWWP3B (Homo sapiens) | 6480464 | afimoxifene inhibits the reaction [Estrogens results in decreased expression of PWWP3B mRNA] | CTD | PMID:21233418 | Pwwp3b | Rat | aflatoxin B1 | increases methylation | ISO | PWWP3B (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of PWWP3B intron | CTD | PMID:30157460 | Pwwp3b | Rat | all-trans-retinoic acid | increases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | Tretinoin results in increased expression of PWWP3B mRNA | CTD | PMID:21934132 | Pwwp3b | Rat | benzo[a]pyrene | affects methylation | ISO | PWWP3B (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of PWWP3B intron | CTD | PMID:30157460 | Pwwp3b | Rat | benzo[a]pyrene | increases methylation | ISO | PWWP3B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of MUM1L1 5' UTR | CTD | PMID:27901495 | Pwwp3b | Rat | benzo[a]pyrene | decreases expression | ISO | Pwwp3b (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of PWWP3B mRNA | CTD | PMID:19770486 more ... | Pwwp3b | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in increased expression of PWWP3B mRNA | CTD | PMID:26496021 | Pwwp3b | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PWWP3B mRNA | CTD | PMID:25181051 and PMID:34947998 | Pwwp3b | Rat | cadmium dichloride | decreases expression | ISO | Pwwp3b (Mus musculus) | 6480464 | Cadmium Chloride results in decreased expression of PWWP3B mRNA | CTD | PMID:24982889 | Pwwp3b | Rat | CGP 52608 | multiple interactions | ISO | PWWP3B (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to MUM1L1 gene] | CTD | PMID:28238834 | Pwwp3b | Rat | chlordecone | increases expression | ISO | Pwwp3b (Mus musculus) | 6480464 | Chlordecone results in increased expression of PWWP3B mRNA | CTD | PMID:29980752 | Pwwp3b | Rat | chlorpyrifos | increases expression | ISO | Pwwp3b (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of MUM1L1 mRNA | CTD | PMID:32715474 | Pwwp3b | Rat | cyclosporin A | decreases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of PWWP3B mRNA | CTD | PMID:20106945 and PMID:27989131 | Pwwp3b | Rat | dorsomorphin | multiple interactions | ISO | PWWP3B (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Pwwp3b | Rat | doxorubicin | decreases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of PWWP3B mRNA | CTD | PMID:29803840 | Pwwp3b | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of PWWP3B mRNA | CTD | PMID:29391264 | Pwwp3b | Rat | ethanol | affects expression | ISO | Pwwp3b (Mus musculus) | 6480464 | Ethanol affects the expression of PWWP3B mRNA | CTD | PMID:30319688 | Pwwp3b | Rat | folic acid | decreases expression | ISO | Pwwp3b (Mus musculus) | 6480464 | Folic Acid results in decreased expression of MUM1L1 mRNA | CTD | PMID:25629700 | Pwwp3b | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of PWWP3B gene | CTD | PMID:22079235 | Pwwp3b | Rat | glycidol | increases expression | EXP | | 6480464 | glycidol results in increased expression of PWWP3B mRNA | CTD | PMID:24395379 | Pwwp3b | Rat | glyphosate | decreases expression | EXP | | 6480464 | Glyphosate results in decreased expression of PWWP3B mRNA | CTD | PMID:38314887 | Pwwp3b | Rat | iron dichloride | decreases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | ferrous chloride results in decreased expression of PWWP3B mRNA | CTD | PMID:35984750 | Pwwp3b | Rat | methylmercury chloride | decreases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of PWWP3B mRNA | CTD | PMID:23179753 more ... | Pwwp3b | Rat | monosodium L-glutamate | increases expression | ISO | Pwwp3b (Mus musculus) | 6480464 | Sodium Glutamate results in increased expression of PWWP3B mRNA | CTD | PMID:22078008 | Pwwp3b | Rat | paracetamol | decreases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of PWWP3B mRNA | CTD | PMID:29067470 | Pwwp3b | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of MUM1L1 mRNA | CTD | PMID:33387578 | Pwwp3b | Rat | perfluorooctane-1-sulfonic acid | decreases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of PWWP3B mRNA | CTD | PMID:27153767 | Pwwp3b | Rat | phenylmercury acetate | increases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of PWWP3B mRNA | CTD | PMID:26272509 | Pwwp3b | Rat | phenylmercury acetate | multiple interactions | ISO | PWWP3B (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PWWP3B mRNA | CTD | PMID:27188386 | Pwwp3b | Rat | pirinixic acid | multiple interactions | ISO | PWWP3B (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of PWWP3B mRNA | CTD | PMID:19710929 | Pwwp3b | Rat | progesterone | increases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | Progesterone results in increased expression of PWWP3B mRNA | CTD | PMID:20864642 | Pwwp3b | Rat | SB 431542 | multiple interactions | ISO | PWWP3B (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Pwwp3b | Rat | silver atom | decreases expression | ISO | Pwwp3b (Mus musculus) | 6480464 | Silver results in decreased expression of PWWP3B mRNA | CTD | PMID:27131904 | Pwwp3b | Rat | silver(0) | decreases expression | ISO | Pwwp3b (Mus musculus) | 6480464 | Silver results in decreased expression of PWWP3B mRNA | CTD | PMID:27131904 | Pwwp3b | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of PWWP3B mRNA | CTD | PMID:19281266 | Pwwp3b | Rat | sunitinib | decreases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of PWWP3B mRNA | CTD | PMID:31533062 | Pwwp3b | Rat | testosterone | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in decreased expression of MUM1L1 mRNA | CTD | PMID:32741896 | Pwwp3b | Rat | tetrachloromethane | increases expression | ISO | Pwwp3b (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of PWWP3B mRNA | CTD | PMID:27339419 and PMID:31919559 | Pwwp3b | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of PWWP3B mRNA | CTD | PMID:34492290 | Pwwp3b | Rat | trichostatin A | increases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | trichostatin A results in increased expression of PWWP3B mRNA | CTD | PMID:24935251 and PMID:27188386 | Pwwp3b | Rat | triptonide | affects expression | ISO | Pwwp3b (Mus musculus) | 6480464 | triptonide affects the expression of PWWP3B mRNA | CTD | PMID:33045310 | Pwwp3b | Rat | valproic acid | decreases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of PWWP3B mRNA | CTD | PMID:29154799 | Pwwp3b | Rat | valproic acid | decreases methylation | ISO | PWWP3B (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of PWWP3B gene | CTD | PMID:29154799 | Pwwp3b | Rat | valproic acid | multiple interactions | ISO | PWWP3B (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PWWP3B mRNA | CTD | PMID:27188386 | Pwwp3b | Rat | valproic acid | increases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of PWWP3B mRNA | CTD | PMID:23179753 more ... | Pwwp3b | Rat | vorinostat | increases expression | ISO | PWWP3B (Homo sapiens) | 6480464 | Vorinostat results in increased expression of PWWP3B mRNA | CTD | PMID:27188386 | |