Xrcc2 (X-ray repair cross complementing 2) - Rat Genome Database

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Gene: Xrcc2 (X-ray repair cross complementing 2) Rattus norvegicus
Analyze
Symbol: Xrcc2
Name: X-ray repair cross complementing 2
RGD ID: 1564823
Description: Predicted to enable ATP binding activity; ATP-dependent DNA damage sensor activity; and DNA binding activity. Predicted to contribute to four-way junction DNA binding activity. Predicted to be involved in DNA recombination; centrosome cycle; and mitotic cell cycle. Predicted to act upstream of or within several processes, including chordate embryonic development; regulation of apoptotic process; and response to X-ray. Predicted to be located in nucleoplasm. Predicted to be part of Rad51B-Rad51C-Rad51D-XRCC2 complex. Predicted to be active in centrosome and replication fork. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group U; pancreatic cancer; primary ovarian insufficiency 17; and spermatogenic failure 50. Orthologous to human XRCC2 (X-ray repair cross complementing 2); PARTICIPATES IN homologous recombination pathway of double-strand break repair; INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DNA repair protein XRCC2; LOC102553514; LOC499966; RGD1564823; similar to DNA-repair protein XRCC2 (X-ray repair cross-complementing protein 2); uncharacterized LOC102553514; X-ray repair complementing defective repair in Chinese hamster cells 2; X-ray repair cross complementing protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8410,157,130 - 10,237,089 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl410,157,800 - 10,176,407 (+)EnsemblGRCr8
mRatBN7.249,423,873 - 9,502,980 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl49,423,898 - 9,442,482 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx414,422,073 - 14,440,537 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0410,236,354 - 10,254,818 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.048,587,370 - 8,605,854 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.045,842,013 - 5,860,516 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl45,841,998 - 5,860,527 (+)Ensemblrn6Rnor6.0
Rnor_5.045,865,989 - 5,884,492 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.444,817,222 - 4,835,725 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4876,632 - 895,138 (-)NCBICelera
Cytogenetic Map4q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-palmitoylglycerol  (ISO)
acetamide  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amphibole asbestos  (ISO)
barium sulfate  (EXP)
benzo[a]pyrene  (ISO)
biphenyl-4-amine  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
Brevetoxin B  (ISO)
bromoacetate  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
chloroethene  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
cylindrospermopsin  (ISO)
DDE  (ISO)
decabromodiphenyl ether  (EXP)
dibutyl phthalate  (ISO)
dihydroxyacetone  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP,ISO)
ethanol  (ISO)
etoposide  (ISO)
fenthion  (ISO)
folic acid  (ISO)
furan  (EXP)
glycidyl methacrylate  (ISO)
GSK-J4  (ISO)
lucanthone  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
myristicin  (ISO)
N,N-dimethylformamide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
phosphoramide mustard  (EXP)
Ptaquiloside  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
terbufos  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
thiostrepton  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triclosan  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
VX nerve agent  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (IBA,IEA,ISO)
Rad51B-Rad51C-Rad51D-XRCC2 complex  (IBA,IEA,ISO)
replication fork  (IBA,IEA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Regulation of homologous recombination in eukaryotes. Heyer WD, etal., Annu Rev Genet. 2010;44:113-39. doi: 10.1146/annurev-genet-051710-150955.
3. XRCC2 and XRCC3 gene polymorphism and risk of pancreatic cancer. Jiao L, etal., Am J Gastroenterol. 2008 Feb;103(2):360-7. Epub 2007 Nov 6.
4. Significant effect of homologous recombination DNA repair gene polymorphisms on pancreatic cancer survival. Li D, etal., Cancer Res. 2006 Mar 15;66(6):3323-30.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:10422536   PMID:11751635   PMID:11834724   PMID:15979950   PMID:16777961   PMID:17116431   PMID:20207730   PMID:21276791   PMID:23149936  


Genomics

Comparative Map Data
Xrcc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8410,157,130 - 10,237,089 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl410,157,800 - 10,176,407 (+)EnsemblGRCr8
mRatBN7.249,423,873 - 9,502,980 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl49,423,898 - 9,442,482 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx414,422,073 - 14,440,537 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0410,236,354 - 10,254,818 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.048,587,370 - 8,605,854 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.045,842,013 - 5,860,516 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl45,841,998 - 5,860,527 (+)Ensemblrn6Rnor6.0
Rnor_5.045,865,989 - 5,884,492 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.444,817,222 - 4,835,725 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4876,632 - 895,138 (-)NCBICelera
Cytogenetic Map4q11NCBI
XRCC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387152,644,776 - 152,676,141 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7152,644,776 - 152,676,193 (-)Ensemblhg38GRCh38
GRCh377152,341,861 - 152,373,226 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367151,974,516 - 152,004,183 (-)NCBIBuild 36Build 36hg18NCBI36
Build 347151,781,236 - 151,810,898NCBI
Celera7146,907,598 - 146,937,489 (-)NCBICelera
Cytogenetic Map7q36.1NCBI
HuRef7146,154,439 - 146,184,018 (-)NCBIHuRef
CHM1_17152,351,916 - 152,381,649 (-)NCBICHM1_1
T2T-CHM13v2.07153,818,164 - 153,849,721 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27151,670,667 - 151,700,330 (-)NCBI
Xrcc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39525,894,812 - 25,910,795 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl525,894,810 - 25,910,823 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38525,689,814 - 25,705,797 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl525,689,812 - 25,705,825 (-)Ensemblmm10GRCm38
MGSCv37525,195,632 - 25,211,615 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36525,199,879 - 25,215,862 (-)NCBIMGSCv36mm8
Celera522,629,689 - 22,645,599 (-)NCBICelera
Cytogenetic Map5B1NCBI
cM Map512.35NCBI
Xrcc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554916,599,085 - 6,629,439 (-)Ensembl
ChiLan1.0NW_0049554916,579,443 - 6,629,410 (-)NCBIChiLan1.0ChiLan1.0
XRCC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26189,063,506 - 189,091,518 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1741,073,530 - 41,101,676 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07144,229,031 - 144,256,854 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17156,378,685 - 156,406,516 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7156,378,685 - 156,406,516 (-)EnsemblpanPan2panpan1.1
XRCC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11616,402,821 - 16,429,095 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1616,402,933 - 16,429,037 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1617,019,573 - 17,045,315 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01618,134,572 - 18,160,367 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1618,134,726 - 18,160,313 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11616,507,780 - 16,533,550 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01617,088,510 - 17,114,628 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01617,139,622 - 17,165,358 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Xrcc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244051185,118,065 - 5,142,946 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365277,760,719 - 7,785,391 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365277,760,609 - 7,785,360 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XRCC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl184,808,470 - 4,835,802 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1184,808,428 - 4,834,281 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2184,937,262 - 5,312,081 (+)NCBISscrofa10.2Sscrofa10.2susScr3
XRCC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121120,795,188 - 120,827,737 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl21120,795,212 - 120,827,706 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607216,791,808 - 16,824,354 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Xrcc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248004,355,539 - 4,390,016 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248004,352,566 - 4,389,707 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Xrcc2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v16154,861,258 - 154,877,059 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Xrcc2
392 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:338
Count of miRNA genes:193
Interacting mature miRNAs:241
Transcripts:ENSRNOT00000010025
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61408Scl23Serum cholesterol level QTL 230.0005blood HDL phospholipid amount (VT:0010504)serum high density lipoprotein phospholipid level (CMO:0001567)4128392287Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4145429897Rat
8552803Bw144Body weight QTL 14416body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)4135396961Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)4135396961Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4132668025Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4132668025Rat
724557Plsm1Polydactyly-luxate syndrome (PLS) morphotypes QTL 10.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)4128392287Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4132668025Rat
61351Bp33Blood pressure QTL 330.0018arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4128392287Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4140471598Rat
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4842855130449094Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4134142783Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4588999950889999Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4134142783Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)4135396961Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)4135396961Rat
738021Hcar13Hepatocarcinoma resistance QTL 134.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)4133538816Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)4163900697Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4589457557613242Rat
61333Gluco16Glucose level QTL 164.30.00001adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)4131106810Rat
9589097Slep11Serum leptin concentration QTL 115.090.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)4132668025Rat

Markers in Region
D4Rat142  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8410,167,917 - 10,168,133 (+)Marker Load Pipeline
mRatBN7.249,434,008 - 9,434,224 (+)MAPPERmRatBN7.2
Rnor_6.045,852,089 - 5,852,304NCBIRnor6.0
Rnor_5.045,876,065 - 5,876,280UniSTSRnor5.0
RGSC_v3.444,827,297 - 4,827,513RGDRGSC3.4
RGSC_v3.444,827,298 - 4,827,513UniSTSRGSC3.4
Celera4884,845 - 885,060UniSTS
RGSC_v3.144,827,297 - 4,827,513RGD
RH 2.0 Map48.8RGD
SHRSP x BN Map40.0RGD
Cytogenetic Map4q11UniSTS
RH137229  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.249,442,243 - 9,442,407 (+)MAPPERmRatBN7.2
Rnor_6.045,860,324 - 5,860,487NCBIRnor6.0
Rnor_5.045,884,300 - 5,884,463UniSTSRnor5.0
RGSC_v3.444,835,533 - 4,835,696UniSTSRGSC3.4
Celera4876,661 - 876,824UniSTS
Cytogenetic Map4q11UniSTS
RH128395  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.249,442,139 - 9,442,343 (+)MAPPERmRatBN7.2
Rnor_6.045,860,220 - 5,860,423NCBIRnor6.0
Rnor_5.045,884,196 - 5,884,399UniSTSRnor5.0
RGSC_v3.444,835,429 - 4,835,632UniSTSRGSC3.4
Celera4876,725 - 876,928UniSTS
Cytogenetic Map4q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 163 91 90 59 87 59 6 348 186 11 142 79 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000010025   ⟹   ENSRNOP00000010025
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl410,157,821 - 10,176,407 (+)Ensembl
mRatBN7.2 Ensembl49,423,898 - 9,442,482 (+)Ensembl
Rnor_6.0 Ensembl45,841,998 - 5,860,527 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094249   ⟹   ENSRNOP00000096624
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl410,157,810 - 10,167,752 (+)Ensembl
mRatBN7.2 Ensembl49,423,898 - 9,433,843 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000148539   ⟹   ENSRNOP00000107776
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl410,157,800 - 10,174,752 (+)Ensembl
RefSeq Acc Id: NM_001109215   ⟹   NP_001102685
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,157,842 - 10,176,345 (+)NCBI
mRatBN7.249,423,933 - 9,442,436 (+)NCBI
Rnor_6.045,842,013 - 5,860,516 (+)NCBI
Rnor_5.045,865,989 - 5,884,492 (+)NCBI
RGSC_v3.444,817,222 - 4,835,725 (+)RGD
Celera4876,632 - 895,138 (-)RGD
Sequence:
RefSeq Acc Id: XM_039108056   ⟹   XP_038963984
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,157,130 - 10,237,089 (+)NCBI
mRatBN7.249,423,873 - 9,502,980 (+)NCBI
RefSeq Acc Id: XM_039108057   ⟹   XP_038963985
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,157,780 - 10,176,408 (+)NCBI
mRatBN7.249,423,882 - 9,439,259 (+)NCBI
RefSeq Acc Id: XM_063286460   ⟹   XP_063142530
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8410,157,130 - 10,173,029 (+)NCBI
RefSeq Acc Id: NP_001102685   ⟸   NM_001109215
- UniProtKB: D3ZPC8 (UniProtKB/TrEMBL),   A6KJJ4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010025   ⟸   ENSRNOT00000010025
RefSeq Acc Id: XP_038963984   ⟸   XM_039108056
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038963985   ⟸   XM_039108057
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000096624   ⟸   ENSRNOT00000094249
RefSeq Acc Id: XP_063142530   ⟸   XM_063286460
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000107776   ⟸   ENSRNOT00000148539
Protein Domains
RecA family profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZPC8-F1-model_v2 AlphaFold D3ZPC8 1-278 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692777
Promoter ID:EPDNEW_R3301
Type:initiation region
Name:Xrcc2_1
Description:X-ray repair cross complementing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.045,842,033 - 5,842,093EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564823 AgrOrtholog
BioCyc Gene G2FUF-46096 BioCyc
Ensembl Genes ENSRNOG00000007493 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010025 ENTREZGENE
  ENSRNOT00000010025.9 UniProtKB/TrEMBL
  ENSRNOT00000094249.2 UniProtKB/TrEMBL
  ENSRNOT00000148539.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro DNA_recomb/repair_Rad51_C UniProtKB/TrEMBL
  DNA_recomb_RecA/RadB_ATP-bd UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  XRCC2 UniProtKB/TrEMBL
KEGG Report rno:499966 UniProtKB/TrEMBL
NCBI Gene 499966 ENTREZGENE
PANTHER DNA REPAIR PROTEIN XRCC2 UniProtKB/TrEMBL
  PTHR46644 UniProtKB/TrEMBL
Pfam Rad51 UniProtKB/TrEMBL
PhenoGen Xrcc2 PhenoGen
PROSITE RECA_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007493 RatGTEx
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A8I6AQP6_RAT UniProtKB/TrEMBL
  A0ABK0LPQ1_RAT UniProtKB/TrEMBL
  A6KJJ4 ENTREZGENE, UniProtKB/TrEMBL
  D3ZPC8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Xrcc2  X-ray repair cross complementing 2  LOC102553514  uncharacterized LOC102553514  Data merged from RGD:7601567 737654 PROVISIONAL
2016-06-08 Xrcc2  X-ray repair cross complementing 2  Xrcc2  X-ray repair complementing defective repair in Chinese hamster cells 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-18 LOC102553514  uncharacterized LOC102553514      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-06 Xrcc2  X-ray repair complementing defective repair in Chinese hamster cells 2  RGD1564823_predicted  similar to DNA-repair protein XRCC2 (X-ray repair cross-complementing protein 2) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564823_predicted  similar to DNA-repair protein XRCC2 (X-ray repair cross-complementing protein 2) (predicted)  LOC499966  similar to DNA-repair protein XRCC2 (X-ray repair cross-complementing protein 2)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499966  similar to DNA-repair protein XRCC2 (X-ray repair cross-complementing protein 2)      Symbol and Name status set to provisional 70820 PROVISIONAL