Fam181b (family with sequence similarity 181, member B)

Advanced Search (OLGA)

Gene: Fam181b (family with sequence similarity 181, member B) Rattus norvegicus

Analyze

Symbol:

Fam181b

Name:

family with sequence similarity 181, member B

RGD ID:

1564695

Description:

Orthologous to human FAM181B (family with sequence similarity 181 member B); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

hypothetical protein LOC499205; LOC499205; RGD1564695; similar to A830059I20Rik protein; uncharacterized protein LOC499205

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	156,578,821 - 156,580,318 (+)	NCBI		GRCr8
mRatBN7.2	1	147,166,428 - 147,167,925 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	147,149,447 - 147,168,298 (-)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	1	147,124,740 - 147,168,298 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	155,118,556 - 155,120,053 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	162,298,738 - 162,300,235 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	155,172,213 - 155,173,710 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	157,920,786 - 157,922,283 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	157,920,786 - 157,922,274 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	164,164,156 - 164,165,653 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	149,955,641 - 149,957,138 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	145,344,573 - 145,346,070 (+)	NCBI		Celera
Cytogenetic Map	1	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

alpha-Zearalanol (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium sulfate (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

Cuprizon (EXP)

decabromodiphenyl ether (EXP)

dibenz[a,h]anthracene (ISO)

dibutyl phthalate (ISO)

dorsomorphin (ISO)

entinostat (ISO)

fenvalerate (EXP)

gentamycin (EXP)

Indeno[1,2,3-cd]pyrene (ISO)

iron dichloride (ISO)

lead(0) (ISO)

methotrexate (ISO)

mono(2-ethylhexyl) phthalate (ISO)

N-methyl-4-phenylpyridinium (ISO)

ozone (ISO)

paracetamol (EXP)

perfluorooctanoic acid (EXP)

phenylmercury acetate (ISO)

progesterone (ISO)

rotenone (ISO)

SB 431542 (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

trimellitic anhydride (ISO)

valproic acid (ISO)

vorinostat (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932

Genomics

Comparative Map Data

Fam181b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	1	156,578,821 - 156,580,318 (+)	NCBI		GRCr8
mRatBN7.2	1	147,166,428 - 147,167,925 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	1	147,149,447 - 147,168,298 (-)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	1	147,124,740 - 147,168,298 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	1	155,118,556 - 155,120,053 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	1	162,298,738 - 162,300,235 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	1	155,172,213 - 155,173,710 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	1	157,920,786 - 157,922,283 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	1	157,920,786 - 157,922,274 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	164,164,156 - 164,165,653 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	149,955,641 - 149,957,138 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	1	145,344,573 - 145,346,070 (+)	NCBI		Celera
Cytogenetic Map	1	q32	NCBI

FAM181B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	82,729,940 - 82,733,864 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	82,729,940 - 82,733,864 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	82,440,982 - 82,444,906 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	82,120,694 - 82,122,554 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	11	79,752,906 - 79,754,766 (-)	NCBI		Celera
Cytogenetic Map	11	q14.1	NCBI
HuRef	11	78,740,310 - 78,742,170 (-)	NCBI		HuRef
CHM1_1	11	82,327,034 - 82,328,894 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	82,666,398 - 82,670,322 (-)	NCBI		T2T-CHM13v2.0

Fam181b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	92,729,087 - 92,730,929 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	7	92,729,073 - 92,731,074 (+)	Ensembl		GRCm39 Ensembl
GRCm38	7	93,079,879 - 93,081,722 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	93,079,865 - 93,081,867 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	100,228,389 - 100,230,232 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	7	92,955,111 - 92,956,914 (+)	NCBI		MGSCv36	mm8
Celera	7	90,359,125 - 90,360,963 (+)	NCBI		Celera
Cytogenetic Map	7	E1	NCBI
cM Map	7	51.66	NCBI

Fam181b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955414	9,798,441 - 9,800,232 (+)	NCBI	ChiLan1.0	ChiLan1.0

FAM181B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	83,662,436 - 83,668,793 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	84,713,661 - 84,717,591 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	77,796,801 - 77,800,010 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	81,409,866 - 81,415,350 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

FAM181B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	16,355,669 - 16,357,654 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	16,355,847 - 16,357,249 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	16,233,421 - 16,235,033 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	16,544,371 - 16,546,114 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	16,544,418 - 16,545,719 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	16,318,794 - 16,320,537 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	16,399,404 - 16,401,145 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	16,469,287 - 16,471,030 (+)	NCBI		UU_Cfam_GSD_1.0

FAM181B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	16,921,724 - 16,923,001 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	16,921,290 - 16,923,142 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	18,783,549 - 18,785,401 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FAM181B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	73,924,794 - 73,927,035 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	73,925,227 - 73,926,507 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	51,780,802 - 51,782,973 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fam181b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624845	7,174,693 - 7,175,949 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624845	7,174,243 - 7,176,186 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Fam181b
6 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	89
Count of miRNA genes:	78
Interacting mature miRNAs:	82
Transcripts:	ENSRNOT00000014284
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61442	Strs1	Sensitivity to stroke QTL 1	7.4		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	1	121767634	166767634	Rat
1578780	Cm52	Cardiac mass QTL 52	3.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	1	81591954	219808434	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49393172	159356837	Rat
2302378	Insul11	Insulin level QTL 11	3.25		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	1	144267353	251128347	Rat
1598866	Bp287	Blood pressure QTL 287	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121006655	166006655	Rat
1578770	Stresp23	Stress response QTL 23			kidney sympathetic nerve activity (VT:0004050)	stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)	1	123350408	182418476	Rat
9590300	Scort16	Serum corticosterone level QTL 16	4.39	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	1	103111621	148111621	Rat
70160	Bw18	Body weight QTL 18	5.7		body mass (VT:0001259)	body weight (CMO:0000012)	1	144267353	196383668	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	57336763	151090257	Rat
7794788	Mcs32	Mammary carcinoma susceptibility QTL 32	2.61		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	1	115540693	238914717	Rat
631199	Cm23	Cardiac mass QTL 23	4.6	0.0004	heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	115585465	172949803	Rat
1598850	Bp297	Blood pressure QTL 297	2.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121006655	166006655	Rat
152025235	Bw194	Body weight QTL 194	4.86		body mass (VT:0001259)		1	123556856	242907031	Rat
1598853	Memor3	Memory QTL 3	4.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	1	143506580	212458660	Rat
152025232	Bw192	Body weight QTL 192	3.93		body mass (VT:0001259)		1	117917486	196963478	Rat
724521	Uae1	Urinary albumin excretion QTL 1	3.8	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	1	90508614	173018436	Rat
1358902	Bw47	Body weight QTL 47	1.67		body mass (VT:0001259)	body weight (CMO:0000012)	1	90508614	180359386	Rat
61348	Bp30	Blood pressure QTL 30	2.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	144017057	197814409	Rat
8655649	Arrd1	Age-related retinal degeneration QTL 1	4.89		retinal layer morphology trait (VT:0003727)	percentage of study population developing retinopathy during a period of time (CMO:0002453)	1	100357752	183970443	Rat
731168	Bp154	Blood pressure QTL 154	3.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94642644	214537671	Rat
631202	Gluco13	Glucose level QTL 13		0.0001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	1	131763437	159756369	Rat
631205	Bp196	Blood pressure QTL 196	4	0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118944897	199050459	Rat
1300158	Bp173	Blood pressure QTL 173	3.48		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	1	115540693	185145286	Rat
631206	Niddm40	Non-insulin dependent diabetes mellitus QTL 40			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	136745990	163747690	Rat
737828	Hcas3	Hepatocarcinoma susceptibility QTL 3	4.9		liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	1	144267353	222987745	Rat
1331749	Hrtrt11	Heart rate QTL 11	2.973		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	94494440	198211706	Rat
1331751	Bp199	Blood pressure QTL 199	3.60022		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	94494440	181830018	Rat
9685799	Bp375	Blood pressure QTL 375			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	170611501	Rat
2293140	Bp313	Blood pressure QTL 313			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	121833674	166833674	Rat
9685802	Bp376	Blood pressure QTL 376			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	126540680	171540680	Rat
724529	Cm16	Cardiac mass QTL 16	2.7		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	1	87580395	150700247	Rat
61370	Mcs3	Mammary carcinoma susceptibility QTL 3	2.15		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	1	102268556	147268556	Rat
1641895	Bp298	Blood pressure QTL 298			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	123350408	182418476	Rat
70209	Niddm23	Non-insulin dependent diabetes mellitus QTL 23	2.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	94494440	198324465	Rat
631496	Bp97	Blood pressure QTL 97	3.08		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	106047847	151047847	Rat
634315	Niddm45	Non-insulin dependent diabetes mellitus QTL 45	7.16		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	1	144267916	172949660	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49393289	199050459	Rat
61379	Bp44	Blood pressure QTL 44	19.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	144267916	174133260	Rat
2303591	Gluco41	Glucose level QTL 41	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	102168504	147168504	Rat
1331793	Bp200	Blood pressure QTL 200	3.71601		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	94494440	172949803	Rat
2313060	Bss71	Bone structure and strength QTL 71	2.6	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	1	118944747	163944747	Rat
6893347	Bw98	Body weight QTL 98	0.2	0.53	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
1354591	Cm36	Cardiac mass QTL 36	4.1		heart left ventricle mass (VT:0007031)	calculated heart weight (CMO:0000073)	1	102813953	201278233	Rat
724550	Thym3	Thymus enlargement QTL 3	7.82	0.001	thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	136829932	181829932	Rat
7421630	Bp362	Blood pressure QTL 362		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	118608292	241799120	Rat
71118	Thym1	Thymus enlargement QTL 1	10.17	0.001	thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	1	136829932	181829932	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32356093	162846471	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	32737458	199368955	Rat
631519	Pia11	Pristane induced arthritis QTL 11	5.3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	1	136830018	181830018	Rat
6893361	Bw104	Body weight QTL 104	0.59	0.27	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
738006	Anxrr14	Anxiety related response QTL 14	4	0.00035	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	130636910	175636910	Rat
1558645	Bw55	Body weight QTL 55	3.2	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	1	133680936	178680936	Rat
1354615	Cm32	Cardiac mass QTL 32	5.2		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	1	102813953	201278233	Rat
634348	Bp138	Blood pressure QTL 138			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	168883176	Rat
8694370	Bw154	Body weight QTL 154	8.91	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	1	103111621	148111621	Rat
738028	Anxrr12	Anxiety related response QTL 12	4.9	0.00001	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	1	130636910	175636910	Rat
1354623	Rf46	Renal function QTL 46	3.8		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	1	102813953	151162766	Rat
631654	Bp107	Blood pressure QTL 107			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	125611501	170611501	Rat
631544	Bp84	Blood pressure QTL 84	5.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350408	181759564	Rat
152025212	Bw190	Body weight QTL 190	5.7		body mass (VT:0001259)		1	123556856	196963478	Rat
631549	Bp89	Blood pressure QTL 89	5.7		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	123350581	201284552	Rat
1358189	Cstrr1	Cold stress response QTL 1		0.0001	catecholamine amount (VT:0010543)	urine norepinephrine level (CMO:0001629)	1	123350408	182418476	Rat
1354606	Bp246	Blood pressure QTL 246	3.6		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	102813953	218753816	Rat

Markers in Region

BE106340

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	147,166,714 - 147,166,898 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	157,921,073 - 157,921,256	NCBI	Rnor6.0
Rnor_5.0	1	164,164,443 - 164,164,626	UniSTS	Rnor5.0
RGSC_v3.4	1	149,955,928 - 149,956,111	UniSTS	RGSC3.4
Celera	1	145,344,860 - 145,345,043	UniSTS
RH 3.4 Map	1	1133.9	UniSTS
Cytogenetic Map	1	q32	UniSTS

UniSTS:235710

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	1	147,167,803 - 147,168,190 (+)	MAPPER	mRatBN7.2
Rnor_6.0	1	157,922,162 - 157,922,548	NCBI	Rnor6.0
Rnor_5.0	1	164,165,532 - 164,165,918	UniSTS	Rnor5.0
RGSC_v3.4	1	149,957,017 - 149,957,403	UniSTS	RGSC3.4
Celera	1	145,345,949 - 145,346,335	UniSTS
Cytogenetic Map	1	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
8	10	49	112	44	41	13	16	13	6	155	87	93	40	60	28

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001109150	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC158703	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473956	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000014284 ⟹ ENSRNOP00000014284

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	147,149,447 - 147,168,298 (-)	Ensembl
Rnor_6.0 Ensembl	1	157,920,786 - 157,922,274 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000014369 ⟹ ENSRNOP00000078671

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	147,124,773 - 147,167,931 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000094920 ⟹ ENSRNOP00000080388

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	147,156,588 - 147,168,298 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112886 ⟹ ENSRNOP00000094271

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	147,124,740 - 147,168,298 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000116885 ⟹ ENSRNOP00000083845

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	1	147,124,740 - 147,168,298 (+)	Ensembl

RefSeq Acc Id:

NM_001109150 ⟹ NP_001102620

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	1	156,578,821 - 156,580,318 (+)	NCBI
mRatBN7.2	1	147,166,428 - 147,167,925 (+)	NCBI
Rnor_6.0	1	157,920,786 - 157,922,283 (+)	NCBI
Rnor_5.0	1	164,164,156 - 164,165,653 (+)	NCBI
RGSC_v3.4	1	149,955,641 - 149,957,138 (+)	RGD
Celera	1	145,344,573 - 145,346,070 (+)	RGD

Sequence:

show sequence

CTTGGGTCGGAGCGAGCAGACAGCGCAGCGCCTGGGCGGGAGCAGGCTGGGTGAACACCGGCCG
CGCTGCGGACCGCTTGAGAGCCGCGGAGATGGCGGTGCAGGCTGCGCTGCTCAGCTCGCACCCC
TTCATACCCTTCGGTTTCGGAGGCTCTGCGGACGGGCTGGTGAGCGCCTTCGGAAGTCTGGACA
AGGGCTGCTGTTTCGAAGATGATGAGAGCGCGGTGTCCGCTGGAGCGCTGCTGTCCGGGTCCGA
CGGCGGGGACGTGCGCGAGGCCACCCGGGACCTGCTCAGCTTCATAGACTCGGCGTCCAGCAAC
ATCAAACTGGCGCTGGACAAGCCAGGCAAGTCCAAGCGGAAAGTGAACCACCGCAAGTACTTGC
AGAAGCAGATCAAACGTTGCAGTGGCCTCATGGGTACCGCACCTCCGAGACCGCCGTCCCCGAG
CTCCACAGACACTTCAGCCAAACGGCCGCCCGGAGCCCCAGGAGCCTCGACTGTCGCGACCCCG
GCGCACTGTAAGGCCGCCCCGCGGAGGGAGGCGACCCAGGCTGCAGCTGCCGCCAGCCTGCAGA
GCCGGAGCTTGGCTGCCCTTTTCGACTCTCTGCGCCACATCCCCGGGGGAGCGGAGACCGCAGG
CGGTGCGGTGGCCGCGTCGGTCCCGGGCCTTGGGGCAGCAAGCTCTGCGGGAGACAGGGCGGGC
ACCTCGGCGAGCTCAGTGGCTCCGGGTACCAGGAAGGTCCCTCTGCGCGCCAGAAACCTGCCCC
CCTCCTTCTTCACGGAGCCATCCCGGGTGGGCTGCTGTGGCGGCGGCGGCCCCTCGGGCCAGGG
TGTGAGCCTGGGTGACCTGGAGAAAGGGGCGGAGGCCGTTGAGTTCTTTGAGTTGCTGGCGCCG
GACTTCAGCACTGGCAACGATTCGGGTGTCTTGCTGGCCGCTGACCCTCTCGACCCGTTCCCCG
CCGGAGCCACGGTCCTACGGGGACCCCTGGAGCTGGAGTCCGTCCCCTTTGAGCAGCCGGCGAT
GGTGGGGAACCTACTATACCCCGAACCCTGGAACACCCCGAGCTGTCCTCAGAGCAAGAAGCCT
CCTCTGCCTGGCGTTCGAGGCAACATGACCTTGAACGAGCCTGTGCGCCTCTTGTACCCCACAG
CCTTGGACTCACCGGGCGGGGAGGACGCACCAGCCTTAGCCTCTTTCACCCCCTTCTTCCCAGA
TTGTGCGCTGCCGCCGCCCCATCAGGTGTCCTACGATTACAGCGCGGGCTACAGCCGCGCGGTT
TACCCCAGCCTCTGGAGACCAGACGGGGTCTGGGAAGGGGCTTCTGGGGAGGAGGGAGCGCATC
CAGACTGACTGCGAGGAACCCTTTCCTTCCCTTATGACTACTGTGGGCTGCGTGCCACCATGGG
TTTCTTCTGAGTGGAGAGAACGACGGGATCACGCATGTGAAGATGAAATGGGATTAAAAAAAAT
AAAACCGCGATCCATTTAATAAAGAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001102620	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI58704	(Get FASTA)	NCBI Sequence Viewer
	EDM18510	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000014284.5
	ENSRNOP00000078671.1
	ENSRNOP00000080388.1
	ENSRNOP00000083845.1
	ENSRNOP00000094271.1

RefSeq Acc Id:

NP_001102620 ⟸ NM_001109150

- UniProtKB:

B0BN67 (UniProtKB/TrEMBL), A6I670 (UniProtKB/TrEMBL), A0A8I5ZNU9 (UniProtKB/TrEMBL), A0A8I5ZXH0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAVQAALLSSHPFIPFGFGGSADGLVSAFGSLDKGCCFEDDESAVSAGALLSGSDGGDVREATR
DLLSFIDSASSNIKLALDKPGKSKRKVNHRKYLQKQIKRCSGLMGTAPPRPPSPSSTDTSAKRP
PGAPGASTVATPAHCKAAPRREATQAAAAASLQSRSLAALFDSLRHIPGGAETAGGAVAASVPG
LGAASSAGDRAGTSASSVAPGTRKVPLRARNLPPSFFTEPSRVGCCGGGGPSGQGVSLGDLEKG
AEAVEFFELLAPDFSTGNDSGVLLAADPLDPFPAGATVLRGPLELESVPFEQPAMVGNLLYPEP
WNTPSCPQSKKPPLPGVRGNMTLNEPVRLLYPTALDSPGGEDAPALASFTPFFPDCALPPPHQV
SYDYSAGYSRAVYPSLWRPDGVWEGASGEEGAHPD

hide sequence

Ensembl Acc Id:

ENSRNOP00000014284 ⟸ ENSRNOT00000014284

Ensembl Acc Id:

ENSRNOP00000078671 ⟸ ENSRNOT00000014369

Ensembl Acc Id:

ENSRNOP00000083845 ⟸ ENSRNOT00000116885

Ensembl Acc Id:

ENSRNOP00000080388 ⟸ ENSRNOT00000094920

Ensembl Acc Id:

ENSRNOP00000094271 ⟸ ENSRNOT00000112886

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B0BN67-F1-model_v2	AlphaFold	B0BN67	1-419	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13690200

Promoter ID:

EPDNEW_R725

Type:

single initiation site

Name:

Fam181b_1

Description:

family with sequence similarity 181, member B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	157,920,803 - 157,920,863	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1564695	AgrOrtholog
BioCyc Gene	G2FUF-58486	BioCyc
Ensembl Genes	ENSRNOG00000010763	Ensembl, UniProtKB/TrEMBL
	ENSRNOG00000069065	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000014284.5	UniProtKB/TrEMBL
	ENSRNOT00000014369.7	UniProtKB/TrEMBL
	ENSRNOT00000094920.1	UniProtKB/TrEMBL
	ENSRNOT00000112886.1	UniProtKB/TrEMBL
	ENSRNOT00000116885.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:9029854	IMAGE-MGC_LOAD
InterPro	FAM181	UniProtKB/TrEMBL
	TEADIR3_omega_loop	UniProtKB/TrEMBL
KEGG Report	rno:499205	UniProtKB/TrEMBL
MGC_CLONE	MGC:187788	IMAGE-MGC_LOAD
NCBI Gene	499205	ENTREZGENE
PANTHER	PROTEIN FAM181B	UniProtKB/TrEMBL
	PTHR33766	UniProtKB/TrEMBL
Pfam	FAM181	UniProtKB/TrEMBL
PhenoGen	Fam181b	PhenoGen
RatGTEx	ENSRNOG00000010763	RatGTEx
	ENSRNOG00000069065	RatGTEx
UniProt	A0A8I5ZNU9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I5ZSZ5_RAT	UniProtKB/TrEMBL
	A0A8I5ZXH0	ENTREZGENE, UniProtKB/TrEMBL
	A6I670	ENTREZGENE
	B0BN67	ENTREZGENE, UniProtKB/TrEMBL
	F7F956_RAT	UniProtKB/TrEMBL
UniProt Secondary	A6I670	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2009-06-12	Fam181b	family with sequence similarity 181, member B	RGD1564695	similar to A830059I20Rik protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1564695	similar to A830059I20Rik protein	RGD1564695_predicted	similar to A830059I20Rik protein (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1564695_predicted	similar to A830059I20Rik protein (predicted)	LOC499205	similar to A830059I20Rik protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC499205	similar to A830059I20Rik protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar