Gene: Lrit2 (leucine-rich repeat, Ig-like and transmembrane domains 2) Rattus norvegicus
Analyze
Symbol:
Lrit2
Name:
leucine-rich repeat, Ig-like and transmembrane domains 2
RGD ID:
1564668
Description:
Predicted to be located in membrane. Orthologous to human LRIT2 (leucine rich repeat, Ig-like and transmembrane domains 2); INTERACTS WITH bisphenol A; 17beta-estradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
leucine-rich repeat, immunoglobulin-like and transmembrane domains 2; leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 2; LOC498594; RGD1564668; similar to leucine rich repeat containing 22
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
LRIT2 (leucine rich repeat, Ig-like and transmembrane domains 2) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Lrit2 (leucine-rich repeat, immunoglobulin-like and transmembrane domains 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):
Lrit2 (leucine rich repeat, Ig-like and transmembrane domains 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
LRIT2 (leucine rich repeat, Ig-like and transmembrane domains 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
LRIT2 (leucine rich repeat, Ig-like and transmembrane domains 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Lrit2 (leucine rich repeat, Ig-like and transmembrane domains 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
LRIT2 (leucine rich repeat, Ig-like and transmembrane domains 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
LRIT2 (leucine rich repeat, Ig-like and transmembrane domains 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Lrit2 (leucine rich repeat, Ig-like and transmembrane domains 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus rattus (black rat):
Lrit2 (leucine rich repeat, Ig-like and transmembrane domains 2) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
LRIT2 (leucine rich repeat, Ig-like and transmembrane domains 2)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Mus musculus (house mouse):
Lrit2 (leucine-rich repeat, immunoglobulin-like and transmembrane domains 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Danio rerio (zebrafish):
lrit2 (leucine-rich repeat, immunoglobulin-like and transmembrane domains 2)
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Drosophila melanogaster (fruit fly):
kek5
Alliance
DIOPT (Ensembl Compara|PANTHER)
Drosophila melanogaster (fruit fly):
kek6
Alliance
DIOPT (Ensembl Compara|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
lrit2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):
lrit2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 16 12,855,257 - 12,860,289 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 16 12,855,257 - 12,860,289 (+) Ensembl GRCr8 mRatBN7.2 16 12,834,996 - 12,840,028 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 16 12,835,051 - 12,839,482 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 16 12,779,340 - 12,783,776 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 16 13,924,075 - 13,928,511 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 16 12,771,836 - 12,776,271 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 16 14,315,980 - 14,325,053 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 16 14,319,777 - 14,324,208 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 16 14,220,595 - 14,226,565 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 16 13,275,634 - 13,280,065 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 16 13,093,227 - 13,097,658 (+) NCBI Celera Cytogenetic Map 16 p14 NCBI
JBrowse:
Only show annotations with direct experimental evidence (0 objects hidden)
Lrit2 Rat 17beta-estradiol decreases expression ISO Lrit2 (Mus musculus) 6480464 Estradiol results in decreased expression of LRIT2 mRNA CTD PMID:39298647 Lrit2 Rat 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Lrit2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of LRIT2 mRNA CTD PMID:21570461|PMID:26377647 Lrit2 Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Lrit2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of LRIT2 mRNA CTD PMID:26290441 Lrit2 Rat 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO Lrit2 (Mus musculus) 6480464 3,4,3',4'-tetrachlorobiphenyl inhibits the reaction [Dietary Fats results in increased expression of LRIT2 mRNA] CTD PMID:19467301 Lrit2 Rat 4,4'-sulfonyldiphenol decreases expression ISO Lrit2 (Mus musculus) 6480464 bisphenol S results in decreased expression of LRIT2 mRNA CTD PMID:39298647 Lrit2 Rat aflatoxin B1 decreases methylation ISO LRIT2 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of LRIT2 gene CTD PMID:27153756 Lrit2 Rat benzo[a]pyrene decreases methylation ISO LRIT2 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased methylation of LRIT2 exon; Benzo(a)pyrene results in decreased methylation of LRIT2 more ... CTD PMID:27901495 Lrit2 Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of LRIT2 mRNA CTD PMID:25181051 Lrit2 Rat bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of LRIT2 gene CTD PMID:28505145 Lrit2 Rat bisphenol F decreases expression ISO Lrit2 (Mus musculus) 6480464 bisphenol F results in decreased expression of LRIT2 mRNA CTD PMID:38685157 Lrit2 Rat cadmium atom multiple interactions ISO Lrit2 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LRIT2 more ... CTD PMID:37236586 Lrit2 Rat cadmium dichloride multiple interactions ISO Lrit2 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LRIT2 more ... CTD PMID:37236586 Lrit2 Rat carbon nanotube decreases expression ISO Lrit2 (Mus musculus) 6480464 Nanotubes, Carbon analog results in decreased expression of LRIT2 mRNA CTD PMID:25620056 Lrit2 Rat CGP 52608 multiple interactions ISO LRIT2 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to LRIT2 gene] CTD PMID:28238834 Lrit2 Rat epoxiconazole decreases expression ISO Lrit2 (Mus musculus) 6480464 epoxiconazole results in decreased expression of LRIT2 mRNA CTD PMID:35436446 Lrit2 Rat N-nitrosodiethylamine decreases expression ISO Lrit2 (Mus musculus) 6480464 Diethylnitrosamine results in decreased expression of LRIT2 mRNA CTD PMID:24535843 Lrit2 Rat paracetamol affects expression ISO Lrit2 (Mus musculus) 6480464 Acetaminophen affects the expression of LRIT2 mRNA CTD PMID:17562736 Lrit2 Rat perfluorooctane-1-sulfonic acid multiple interactions ISO Lrit2 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of LRIT2 mRNA CTD PMID:36331819 Lrit2 Rat pirinixic acid decreases expression ISO Lrit2 (Mus musculus) 6480464 pirinixic acid results in decreased expression of LRIT2 mRNA CTD PMID:23811191 Lrit2 Rat potassium dichromate increases expression ISO Lrit2 (Mus musculus) 6480464 Potassium Dichromate results in increased expression of LRIT2 mRNA CTD PMID:23608068 Lrit2 Rat tetrachloromethane decreases expression ISO Lrit2 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of LRIT2 mRNA CTD PMID:27339419|PMID:31919559
References
Genomics
Comparative Map Data
Lrit2 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 16 12,855,257 - 12,860,289 (+) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 16 12,855,257 - 12,860,289 (+) Ensembl GRCr8 mRatBN7.2 16 12,834,996 - 12,840,028 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 16 12,835,051 - 12,839,482 (+) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 16 12,779,340 - 12,783,776 (+) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 16 13,924,075 - 13,928,511 (+) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 16 12,771,836 - 12,776,271 (+) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 16 14,315,980 - 14,325,053 (+) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 16 14,319,777 - 14,324,208 (+) Ensembl rn6 Rnor6.0 Rnor_5.0 16 14,220,595 - 14,226,565 (+) NCBI Rnor_5.0 Rnor_5.0 rn5 RGSC_v3.4 16 13,275,634 - 13,280,065 (+) NCBI RGSC_v3.4 RGSC_v3.4 rn4 Celera 16 13,093,227 - 13,097,658 (+) NCBI Celera Cytogenetic Map 16 p14 NCBI
LRIT2 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 10 84,220,485 - 84,225,589 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 10 84,220,571 - 84,225,544 (-) Ensembl hg38 GRCh38 GRCh37 10 85,980,241 - 85,985,345 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 10 85,970,221 - 85,975,264 (-) NCBI Build 36 Build 36 hg18 NCBI36 Celera 10 79,975,750 - 79,980,793 (-) NCBI Celera Cytogenetic Map 10 q23.1 NCBI HuRef 10 79,825,720 - 79,830,763 (-) NCBI HuRef CHM1_1 10 86,262,008 - 86,267,051 (-) NCBI CHM1_1 T2T-CHM13v2.0 10 85,099,011 - 85,104,115 (-) NCBI T2T-CHM13v2.0
Lrit2 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 14 36,784,923 - 36,795,700 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 14 36,789,886 - 36,795,700 (+) Ensembl GRCm39 Ensembl GRCm39 GRCm38 14 37,064,433 - 37,073,743 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 14 37,067,929 - 37,073,743 (+) Ensembl mm10 GRCm38 MGSCv37 14 37,881,235 - 37,886,921 (+) NCBI MGSCv37 MGSCv37 mm9 NCBIm37 MGSCv36 14 35,979,290 - 35,984,976 (+) NCBI MGSCv36 mm8 Celera 14 33,279,110 - 33,284,754 (+) NCBI Celera Cytogenetic Map 14 B NCBI cM Map 14 21.29 NCBI
Lrit2 Chinchilla Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChiLan1.0 Ensembl NW_004955510 3,732,436 - 3,736,557 (-) Ensembl ChiLan1.0 NW_004955510 3,732,436 - 3,736,557 (-) NCBI ChiLan1.0 ChiLan1.0
LRIT2 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 8 96,201,349 - 96,207,644 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 10 96,206,669 - 96,212,964 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 10 80,636,045 - 80,641,129 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 10 84,205,958 - 84,211,052 (-) NCBI PanPan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 10 84,205,967 - 84,211,052 (-) Ensembl panPan2 panpan1.1
LRIT2 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 4 32,464,825 - 32,468,988 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 4 32,464,825 - 32,468,988 (-) Ensembl canFam3 CanFam3.1 Dog10K_Boxer_Tasha 4 32,450,256 - 32,454,419 (-) NCBI Dog10K_Boxer_Tasha Dog10K_Boxer_Tasha ROS_Cfam_1.0 4 32,780,362 - 32,784,526 (-) NCBI ROS_Cfam_1.0 ROS_Cfam_1.0 ROS_Cfam_1.0 Ensembl 4 32,780,362 - 32,784,526 (-) Ensembl ROS_Cfam_1.0 Ensembl UMICH_Zoey_3.1 4 32,642,970 - 32,647,135 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 4 32,835,251 - 32,839,416 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 4 33,331,859 - 33,336,023 (-) NCBI UU_Cfam_GSD_1.0 UU_Cfam_GSD_1.0
Lrit2
LRIT2 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 14 85,460,549 - 85,465,274 (-) Ensembl susScr11 Sscrofa11.1 Sscrofa11.1 14 85,461,325 - 85,465,274 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 14 92,266,178 - 92,270,127 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
LRIT2 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 9 47,603,280 - 47,610,230 (+) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 9 47,604,868 - 47,608,805 (+) Ensembl ChlSab1.1 Ensembl chlSab2 Vervet-AGM Vero_WHO_p1.0 NW_023666048 7,781,490 - 7,786,836 (+) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Lrit2
Lrit2
miRNA Target Status (No longer updated)
Predicted Target Of
Count of predictions: 66 Count of miRNA genes: 57 Interacting mature miRNAs: 60 Transcripts: ENSRNOT00000038771 Prediction methods: Microtar, Miranda, Rnahybrid, Targetscan Result types: miRGate_prediction 
