Zfp275 (zinc finger protein 275) - Rat Genome Database

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Gene: Zfp275 (zinc finger protein 275) Rattus norvegicus
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Symbol: Zfp275
Name: zinc finger protein 275
RGD ID: 1564630
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZNF275 (zinc finger protein 275); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC293849; RGD1564630; similar to Zinc finger protein 275
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X156,208,873 - 156,225,732 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX156,208,914 - 156,225,617 (+)EnsemblGRCr8
mRatBN7.2X151,057,530 - 151,074,392 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX151,057,573 - 151,074,276 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX153,198,749 - 153,215,452 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X156,761,952 - 156,778,655 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X154,433,780 - 154,450,483 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X157,457,399 - 157,474,263 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX157,457,515 - 157,474,219 (-)Ensemblrn6Rnor6.0
Rnor_5.01153,203,960 - 153,220,664 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X159,237,895 - 159,254,814 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1136,815,329 - 136,832,032 (-)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA,IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Zfp275
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X156,208,873 - 156,225,732 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX156,208,914 - 156,225,617 (+)EnsemblGRCr8
mRatBN7.2X151,057,530 - 151,074,392 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX151,057,573 - 151,074,276 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX153,198,749 - 153,215,452 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X156,761,952 - 156,778,655 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X154,433,780 - 154,450,483 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X157,457,399 - 157,474,263 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX157,457,515 - 157,474,219 (-)Ensemblrn6Rnor6.0
Rnor_5.01153,203,960 - 153,220,664 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X159,237,895 - 159,254,814 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1136,815,329 - 136,832,032 (-)NCBICelera
Cytogenetic MapXq37NCBI
ZNF275
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X153,352,029 - 153,360,109 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX153,334,147 - 153,360,110 (+)Ensemblhg38GRCh38
GRCh37X152,617,487 - 152,625,567 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X152,262,060 - 152,270,249 (+)NCBIBuild 36Build 36hg18NCBI36
CeleraX152,832,580 - 152,851,303 (+)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX141,258,986 - 141,277,654 (+)NCBIHuRef
CHM1_1X152,491,949 - 152,500,029 (+)NCBICHM1_1
T2T-CHM13v2.0X151,619,558 - 151,627,638 (+)NCBIT2T-CHM13v2.0
Zfp275
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X72,386,190 - 72,402,686 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX72,386,227 - 72,402,686 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X73,342,593 - 73,359,080 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX73,342,621 - 73,359,080 (+)Ensemblmm10GRCm38
MGSCv37X70,587,959 - 70,604,419 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X69,595,355 - 69,611,684 (+)NCBIMGSCv36mm8
CeleraX64,596,476 - 64,612,936 (+)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.29NCBI
Znf275
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495558083,091 - 99,913 (+)Ensembl
ChiLan1.0NW_00495558083,091 - 99,862 (+)NCBIChiLan1.0ChiLan1.0
ZNF275
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X153,373,555 - 153,392,378 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X153,377,159 - 153,395,982 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X142,883,703 - 142,902,526 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X152,771,814 - 152,790,438 (+)NCBIPanPan1.1PanPan1.1panPan2
Znf275
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X118,459,187 - 118,473,323 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936809196,926 - 212,593 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936809196,939 - 212,587 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZNF275
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X127,766,631 - 127,788,874 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606565,628,144 - 65,652,990 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Znf275
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462494656,476 - 73,102 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:765
Count of miRNA genes:295
Interacting mature miRNAs:382
Transcripts:ENSRNOT00000025218
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118973754157758123Rat

Markers in Region
AI593314  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X151,074,152 - 151,074,283 (-)MAPPERmRatBN7.2
Rnor_6.0X157,457,508 - 157,457,638NCBIRnor6.0
Rnor_5.01153,203,953 - 153,204,083UniSTSRnor5.0
RGSC_v3.4X159,254,691 - 159,254,821UniSTSRGSC3.4
Celera1136,815,322 - 136,815,452UniSTS
Cytogenetic MapXq37UniSTS
RH143327  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X151,074,128 - 151,074,257 (-)MAPPERmRatBN7.2
Rnor_6.0X157,457,534 - 157,457,662NCBIRnor6.0
Rnor_5.01153,203,979 - 153,204,107UniSTSRnor5.0
RGSC_v3.4X159,254,667 - 159,254,795UniSTSRGSC3.4
Celera1136,815,348 - 136,815,476UniSTS
Cytogenetic MapXq37UniSTS
BE110181  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X151,065,863 - 151,066,041 (-)MAPPERmRatBN7.2
Rnor_6.0X157,465,750 - 157,465,927NCBIRnor6.0
Rnor_5.01153,212,195 - 153,212,372UniSTSRnor5.0
RGSC_v3.4X159,246,402 - 159,246,579UniSTSRGSC3.4
Celera1136,823,564 - 136,823,741UniSTS
Cytogenetic MapXq37UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 355 192 11 142 80 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000079860   ⟹   ENSRNOP00000075303
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX156,208,914 - 156,225,617 (+)Ensembl
mRatBN7.2 EnsemblX151,057,573 - 151,074,276 (+)Ensembl
Rnor_6.0 EnsemblX157,457,515 - 157,474,219 (-)Ensembl
RefSeq Acc Id: NM_001106343   ⟹   NP_001099813
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,208,914 - 156,225,617 (+)NCBI
mRatBN7.2X151,057,573 - 151,074,276 (+)NCBI
Rnor_6.0X157,457,515 - 157,474,219 (-)NCBI
Rnor_5.01153,203,960 - 153,220,664 (-)NCBI
RGSC_v3.4X159,237,895 - 159,254,814 (+)RGD
Celera1136,815,329 - 136,832,032 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099524   ⟹   XP_038955452
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,208,884 - 156,225,732 (+)NCBI
mRatBN7.2X151,057,531 - 151,074,392 (+)NCBI
RefSeq Acc Id: XM_039099525   ⟹   XP_038955453
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,208,885 - 156,225,732 (+)NCBI
mRatBN7.2X151,057,531 - 151,074,392 (+)NCBI
RefSeq Acc Id: XM_039099526   ⟹   XP_038955454
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,208,884 - 156,225,732 (+)NCBI
mRatBN7.2X151,057,530 - 151,074,392 (+)NCBI
RefSeq Acc Id: XM_039099527   ⟹   XP_038955455
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,208,873 - 156,225,732 (+)NCBI
mRatBN7.2X151,057,531 - 151,074,392 (+)NCBI
RefSeq Acc Id: XM_039099528   ⟹   XP_038955456
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,208,884 - 156,225,732 (+)NCBI
mRatBN7.2X151,057,530 - 151,074,392 (+)NCBI
RefSeq Acc Id: XM_063279835   ⟹   XP_063135905
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X156,208,884 - 156,225,732 (+)NCBI
RefSeq Acc Id: NP_001099813   ⟸   NM_001106343
- UniProtKB: D3ZRH5 (UniProtKB/TrEMBL),   A6KRY9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075303   ⟸   ENSRNOT00000079860
RefSeq Acc Id: XP_038955454   ⟸   XM_039099526
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038955456   ⟸   XM_039099528
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038955452   ⟸   XM_039099524
- Peptide Label: isoform X1
- UniProtKB: D3ZRH5 (UniProtKB/TrEMBL),   A6KRY9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955455   ⟸   XM_039099527
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038955453   ⟸   XM_039099525
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063135905   ⟸   XM_063279835
- Peptide Label: isoform X3
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZRH5-F1-model_v2 AlphaFold D3ZRH5 1-499 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13702062
Promoter ID:EPDNEW_R12586
Type:multiple initiation site
Name:Zfp275_1
Description:zinc finger protein 275
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X157,474,232 - 157,474,292EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564630 AgrOrtholog
BioCyc Gene G2FUF-681 BioCyc
Ensembl Genes ENSRNOG00000061073 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000079860 ENTREZGENE
  ENSRNOT00000079860.3 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:293849 UniProtKB/TrEMBL
NCBI Gene 293849 ENTREZGENE
PANTHER ZFP14 ZINC FINGER PROTEIN-RELATED UniProtKB/TrEMBL
  ZINC FINGER AND BTB DOMAIN-CONTAINING UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PhenoGen Zfp275 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000061073 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A6KRY9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZRH5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Zfp275  zinc finger protein 275   Zfp275_predicted  zinc finger protein 275 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Zfp275_predicted  zinc finger protein 275 (predicted)  RGD1564630_predicted  similar to Zinc finger protein 275 (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1564630_predicted  similar to Zinc finger protein 275 (predicted)  LOC293849  similar to Zinc finger protein 275  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC293849  similar to Zinc finger protein 275      Symbol and Name status set to provisional 70820 PROVISIONAL