Glod5 (glyoxalase domain containing 5) - Rat Genome Database

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Gene: Glod5 (glyoxalase domain containing 5) Rattus norvegicus
Analyze
Symbol: Glod5
Name: glyoxalase domain containing 5
RGD ID: 1564596
Description: Orthologous to human GLOD5 (glyoxalase domain containing 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; aflatoxin B1.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: glyoxalase domain-containing protein 5; LOC302554; RGD1564596; similar to RIKEN cDNA 2010001H14
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X17,145,936 - 17,160,733 (+)NCBIGRCr8
mRatBN7.2X14,473,994 - 14,488,797 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX14,473,994 - 14,488,683 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX19,287,411 - 19,302,084 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X20,781,023 - 20,795,686 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X17,046,193 - 17,060,859 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X15,225,645 - 15,240,458 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,225,645 - 15,240,329 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X16,006,589 - 16,021,387 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,505,715 - 26,520,399 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX14,558,775 - 14,573,352 (+)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Glod5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X17,145,936 - 17,160,733 (+)NCBIGRCr8
mRatBN7.2X14,473,994 - 14,488,797 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX14,473,994 - 14,488,683 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX19,287,411 - 19,302,084 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X20,781,023 - 20,795,686 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X17,046,193 - 17,060,859 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X15,225,645 - 15,240,458 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX15,225,645 - 15,240,329 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X16,006,589 - 16,021,387 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X26,505,715 - 26,520,399 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX14,558,775 - 14,573,352 (+)NCBICelera
Cytogenetic MapXq12NCBI
GLOD5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X48,761,747 - 48,773,648 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX48,761,747 - 48,773,648 (+)EnsemblGRCh38hg38GRCh38
GRCh37X48,620,151 - 48,632,064 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,508,985 - 48,516,795 (+)NCBINCBI36Build 36hg18NCBI36
CeleraX53,031,515 - 53,043,857 (-)NCBICelera
Cytogenetic MapXp11.23NCBI
HuRefX46,281,675 - 46,289,876 (+)NCBIHuRef
CHM1_1X48,651,323 - 48,663,204 (+)NCBICHM1_1
T2T-CHM13v2.0X48,172,222 - 48,184,150 (+)NCBIT2T-CHM13v2.0
Glod5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X7,870,440 - 7,884,731 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX7,870,439 - 7,884,731 (-)EnsemblGRCm39 Ensembl
GRCm38X8,004,201 - 8,018,492 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX8,004,200 - 8,018,492 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X7,581,327 - 7,595,618 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X7,161,160 - 7,175,451 (-)NCBIMGSCv36mm8
CeleraX3,450,712 - 3,464,719 (+)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX3.61NCBI
Glod5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955543319,985 - 323,393 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955543320,087 - 321,311 (+)NCBIChiLan1.0ChiLan1.0
GLOD5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X50,250,748 - 50,263,035 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X50,254,120 - 50,266,407 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X41,060,152 - 41,071,654 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X48,920,747 - 48,932,442 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX48,920,747 - 48,932,442 (+)Ensemblpanpan1.1panPan2
GLOD5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X41,967,674 - 41,979,241 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX41,967,812 - 41,979,243 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX16,343,245 - 16,354,675 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X42,103,951 - 42,115,447 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX42,104,009 - 42,115,457 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X42,090,023 - 42,101,685 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X42,078,509 - 42,089,940 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X42,172,427 - 42,184,091 (+)NCBIUU_Cfam_GSD_1.0
Glod5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X34,479,155 - 34,491,347 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936721719,651 - 732,078 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936721719,660 - 731,800 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GLOD5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX42,877,140 - 42,889,271 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X42,877,034 - 42,889,285 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GLOD5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X45,888,220 - 45,900,316 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX45,888,509 - 45,900,095 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607611,368,482 - 11,380,354 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Glod5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624893562,330 - 574,594 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624893562,815 - 570,099 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Glod5
74 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:26
Interacting mature miRNAs:31
Transcripts:ENSRNOT00000008648
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X144797220991088Rat
631204Gluco15Glucose level QTL 150.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X162371522646544Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 49 109 84 86 55 25 55 5 212 95 90 45 54 31

Sequence


Ensembl Acc Id: ENSRNOT00000008648   ⟹   ENSRNOP00000008648
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX14,473,994 - 14,488,683 (+)Ensembl
Rnor_6.0 EnsemblX15,225,645 - 15,240,329 (+)Ensembl
RefSeq Acc Id: NM_001106957   ⟹   NP_001100427
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,145,936 - 17,160,619 (+)NCBI
mRatBN7.2X14,473,994 - 14,488,683 (+)NCBI
Rnor_6.0X15,225,645 - 15,240,329 (+)NCBI
Rnor_5.0X16,006,589 - 16,021,387 (+)NCBI
RGSC_v3.4X26,505,715 - 26,520,399 (+)RGD
CeleraX14,558,775 - 14,573,352 (+)RGD
Sequence:
RefSeq Acc Id: XM_006256706   ⟹   XP_006256768
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,156,636 - 17,160,733 (+)NCBI
mRatBN7.2X14,484,774 - 14,488,797 (+)NCBI
Rnor_6.0X15,228,284 - 15,240,458 (+)NCBI
Rnor_5.0X16,006,589 - 16,021,387 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099630   ⟹   XP_038955558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X17,146,241 - 17,160,733 (+)NCBI
mRatBN7.2X14,474,305 - 14,488,797 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001100427 (Get FASTA)   NCBI Sequence Viewer  
  XP_006256768 (Get FASTA)   NCBI Sequence Viewer  
  XP_038955558 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL83807 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000008648.4
RefSeq Acc Id: NP_001100427   ⟸   NM_001106957
- UniProtKB: D3Z9B0 (UniProtKB/TrEMBL),   A6KP59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256768   ⟸   XM_006256706
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000008648   ⟸   ENSRNOT00000008648
RefSeq Acc Id: XP_038955558   ⟸   XM_039099630
- Peptide Label: isoform X1
Protein Domains
VOC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3Z9B0-F1-model_v2 AlphaFold D3Z9B0 1-148 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701734
Promoter ID:EPDNEW_R12258
Type:initiation region
Name:Glod5_1
Description:glyoxalase domain containing 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X15,225,675 - 15,225,735EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564596 AgrOrtholog
BioCyc Gene G2FUF-2941 BioCyc
Ensembl Genes ENSRNOG00000039571 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000008648.6 UniProtKB/TrEMBL
Gene3D-CATH 3.10.180.10 UniProtKB/TrEMBL
InterPro Glyas_Bleomycin-R_OHBP_Dase UniProtKB/TrEMBL
  Glyas_Fos-R_dOase_dom UniProtKB/TrEMBL
  GlyoxalaseI/FosfomycinResist UniProtKB/TrEMBL
  VOC UniProtKB/TrEMBL
KEGG Report rno:302554 UniProtKB/TrEMBL
NCBI Gene 302554 ENTREZGENE
PANTHER GLYOXALASE DOMAIN-CONTAINING PROTEIN 5 UniProtKB/TrEMBL
  GLYOXALASE FAMILY PROTEIN UniProtKB/TrEMBL
Pfam Glyoxalase UniProtKB/TrEMBL
PhenoGen Glod5 PhenoGen
PROSITE VOC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000039571 RatGTEx
Superfamily-SCOP SSF54593 UniProtKB/TrEMBL
UniProt A6KP59 ENTREZGENE, UniProtKB/TrEMBL
  D3Z9B0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-06 Glod5  glyoxalase domain containing 5  RGD1564596_predicted  similar to RIKEN cDNA 2010001H14 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564596_predicted  similar to RIKEN cDNA 2010001H14 (predicted)  LOC302554  similar to RIKEN cDNA 2010001H14  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC302554  similar to RIKEN cDNA 2010001H14      Symbol and Name status set to provisional 70820 PROVISIONAL