Smokwl2 (sperm motility kinase W like 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Smokwl2 (sperm motility kinase W like 2) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Smokwl2 (Ensembl: RGD1564409)
Name: sperm motility kinase W like 2 (Ensembl:similar to hypothetical protein 4930509O22)
RGD ID: 1564409
Description: Predicted to enable ATP binding activity; INTERACTS WITH indole-3-methanol.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC314670; putative sperm motility kinase W; RGD1564409; similar to hypothetical protein 4930509O22; uncharacterized protein RGD1564409; uncharacterized protein Smokwl2
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8719,165,856 - 19,218,009 (+)NCBIGRCr8
mRatBN7.2717,311,785 - 17,330,229 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl717,311,697 - 17,330,495 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0720,262,600 - 20,413,111 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0720,432,424 - 20,435,175 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4719,349,252 - 19,350,733 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Smokwl2
198 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat


Expression


Sequence


RefSeq Acc Id: ENSRNOT00000080523   ⟹   ENSRNOP00000073961
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl717,311,697 - 17,316,359 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000097023   ⟹   ENSRNOP00000091523
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl717,311,697 - 17,330,495 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116313   ⟹   ENSRNOP00000077205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl717,311,697 - 17,330,495 (+)Ensembl
RefSeq Acc Id: XM_039080454   ⟹   XP_038936382
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,199,581 - 19,218,009 (+)NCBI
mRatBN7.2717,311,785 - 17,330,228 (+)NCBI
RefSeq Acc Id: XM_039080455   ⟹   XP_038936383
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,199,581 - 19,218,009 (+)NCBI
mRatBN7.2717,311,785 - 17,330,228 (+)NCBI
RefSeq Acc Id: XM_039080456   ⟹   XP_038936384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,199,581 - 19,218,009 (+)NCBI
mRatBN7.2717,311,785 - 17,330,228 (+)NCBI
RefSeq Acc Id: XM_039080462   ⟹   XP_038936390
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,208,071 - 19,218,009 (+)NCBI
mRatBN7.2717,320,625 - 17,330,229 (+)NCBI
RefSeq Acc Id: XM_063264580   ⟹   XP_063120650
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,199,581 - 19,218,009 (+)NCBI
RefSeq Acc Id: XM_063264581   ⟹   XP_063120651
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,199,581 - 19,218,009 (+)NCBI
RefSeq Acc Id: XM_063264582   ⟹   XP_063120652
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,199,581 - 19,218,009 (+)NCBI
RefSeq Acc Id: XR_010053642
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,165,856 - 19,218,009 (+)NCBI
RefSeq Acc Id: XR_010053643
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8719,182,744 - 19,218,009 (+)NCBI
RefSeq Acc Id: XP_038936382   ⟸   XM_039080454
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K6V9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936384   ⟸   XM_039080456
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K6V9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936383   ⟸   XM_039080455
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K6V9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038936390   ⟸   XM_039080462
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000073961   ⟸   ENSRNOT00000080523
RefSeq Acc Id: ENSRNOP00000077205   ⟸   ENSRNOT00000116313
RefSeq Acc Id: ENSRNOP00000091523   ⟸   ENSRNOT00000097023
RefSeq Acc Id: XP_063120652   ⟸   XM_063264582
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063120650   ⟸   XM_063264580
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063120651   ⟸   XM_063264581
- Peptide Label: isoform X1
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K6V9-F1-model_v2 AlphaFold A0A0G2K6V9 1-484 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-34644 BioCyc
Ensembl Genes ENSRNOG00000057162 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000080523.2 UniProtKB/TrEMBL
  ENSRNOT00000097023.1 UniProtKB/TrEMBL
  ENSRNOT00000116313.1 UniProtKB/TrEMBL
Gene3D-CATH DNA helicase RuvA subunit, C-terminal domain UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene 314670 ENTREZGENE
PANTHER KP78A-RELATED UniProtKB/TrEMBL
  MAP/MICROTUBULE AFFINITY-REGULATING KINASE UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Smokwl2 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000057162 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A0G2K6V9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Smokwl2  sperm motility kinase W like 2  RGD1564409  similar to hypothetical protein 4930509O22  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1564409  similar to hypothetical protein 4930509O22   RGD1564409_predicted  similar to hypothetical protein 4930509O22 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1564409_predicted  similar to hypothetical protein 4930509O22 (predicted)  LOC314670  similar to hypothetical protein 4930509O22  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC314670  similar to hypothetical protein 4930509O22      Symbol and Name status set to provisional 70820 PROVISIONAL