Acbd7 (acyl-CoA binding domain containing 7) - Rat Genome Database

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Gene: Acbd7 (acyl-CoA binding domain containing 7) Rattus norvegicus
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Symbol: Acbd7
Name: acyl-CoA binding domain containing 7
RGD ID: 1564164
Description: Predicted to enable triplet codon-amino acid adaptor activity. Predicted to be involved in translation. Orthologous to human ACBD7 (acyl-CoA binding domain containing 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: acyl-CoA-binding domain-containing protein 7; acyl-Coenzyme A binding domain containing 7; LOC361277; RGD1564164; similar to Acyl-CoA-binding protein (ACBP) (Diazepam binding inhibitor); similar to Acyl-CoA-binding protein (ACBP) (Diazepam binding inhibitor) (DBI) (Endozepine) (EP)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81779,813,106 - 79,821,254 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1779,813,106 - 79,818,448 (-)EnsemblGRCr8
mRatBN7.21774,903,936 - 74,909,977 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1774,903,177 - 74,905,811 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1778,370,487 - 78,375,825 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01782,205,866 - 82,211,204 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01776,253,811 - 76,259,149 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01778,904,549 - 78,913,372 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,904,873 - 78,910,671 (-)Ensemblrn6Rnor6.0
Rnor_5.01780,546,951 - 80,554,663 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41786,022,618 - 86,027,750 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1774,283,333 - 74,288,677 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Acbd7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81779,813,106 - 79,821,254 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1779,813,106 - 79,818,448 (-)EnsemblGRCr8
mRatBN7.21774,903,936 - 74,909,977 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1774,903,177 - 74,905,811 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1778,370,487 - 78,375,825 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01782,205,866 - 82,211,204 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01776,253,811 - 76,259,149 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01778,904,549 - 78,913,372 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,904,873 - 78,910,671 (-)Ensemblrn6Rnor6.0
Rnor_5.01780,546,951 - 80,554,663 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41786,022,618 - 86,027,750 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1774,283,333 - 74,288,677 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
ACBD7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381015,075,475 - 15,088,776 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1015,075,475 - 15,088,776 (-)Ensemblhg38GRCh38
GRCh371015,117,474 - 15,130,775 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361015,157,480 - 15,170,781 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341015,157,480 - 15,170,781NCBI
Celera1015,046,107 - 15,059,408 (-)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1015,028,051 - 15,041,349 (-)NCBIHuRef
CHM1_11015,117,595 - 15,130,889 (-)NCBICHM1_1
T2T-CHM13v2.01015,089,450 - 15,102,751 (-)NCBIT2T-CHM13v2.0
Acbd7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3923,333,850 - 3,342,035 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl23,337,205 - 3,342,030 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3823,332,814 - 3,340,998 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl23,336,168 - 3,340,993 (+)Ensemblmm10GRCm38
MGSCv3723,253,440 - 3,258,269 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3623,253,440 - 3,258,269 (+)NCBIMGSCv36mm8
Celera23,287,768 - 3,292,591 (+)NCBICelera
Cytogenetic Map2A1NCBI
cM Map21.87NCBI
Acbd7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542919,371,693 - 19,372,310 (+)Ensembl
ChiLan1.0NW_00495542919,367,352 - 19,372,358 (+)NCBIChiLan1.0ChiLan1.0
ACBD7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2827,914,233 - 27,937,365 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11027,919,475 - 27,942,691 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01015,389,042 - 15,404,763 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11015,669,766 - 15,686,078 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1015,669,766 - 15,686,078 (-)EnsemblpanPan2panpan1.1
ACBD7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1221,631,458 - 21,639,510 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha218,744,759 - 18,752,685 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0221,932,724 - 21,940,659 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl221,932,748 - 21,942,236 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1219,133,288 - 19,141,195 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0219,968,202 - 19,976,115 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0220,594,806 - 20,602,743 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Acbd7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934416,137,415 - 16,150,418 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365745,633,761 - 5,644,772 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365745,638,054 - 5,644,749 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ACBD7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1046,740,585 - 46,750,606 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11046,740,570 - 46,751,208 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21051,473,758 - 51,482,998 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ACBD7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1915,054,321 - 15,066,045 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605120,596,207 - 20,608,026 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Acbd7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624805466,140 - 472,588 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Acbd7
162 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:125
Count of miRNA genes:99
Interacting mature miRNAs:107
Transcripts:ENSRNOT00000064609
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
152023626Bp403Blood pressure QTL 4033.86arterial blood pressure trait (VT:2000000)172413612784432719Rat
631502Cm26Cardiac mass QTL 263.71heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)177061350286062352Rat
2301412Kidm40Kidney mass QTL 400.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)174238816487388164Rat
1354588Bvd4Brain ventricular dilatation QTL 45.310.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)175819406487388164Rat
1354654Spl7Serum phospholipid level QTL 75.5blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)173803135483031354Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)175482950393515804Rat
1598871Memor5Memory QTL 55.3exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)174096801789341781Rat
1581512Cm55Cardiac mass QTL 552.80.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)172723344583975845Rat
1354629Scl31Serum cholesterol level QTL 314.1blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)173803135483031354Rat
152025238Slep14Serum leptin concentration QTL 144.62blood leptin amount (VT:0005667)172439059584432719Rat
61466Niddm12Non-insulin dependent diabetes mellitus QTL 123.20.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)176515487293515804Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)173803135483031354Rat
1354635Bp245Blood pressure QTL 2456arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)173803135483031354Rat
12904736Cm121Cardiac mass QTL 1210.043heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)174238816487388164Rat
1300148Bp192Blood pressure QTL 1923.47arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)174605012691050126Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175560459793006569Rat
2324621Coatc5Coat color QTL 5coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)174265489587654895Rat
1354619Bp242Blood pressure QTL 2426.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)173768787782687877Rat
1300131Bp193Blood pressure QTL 1933.3arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176855004093515804Rat
7488963Bp369Blood pressure QTL 3690.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)176369714782818564Rat
1300129Rf25Renal function QTL 253.03blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)174106235286062352Rat
1354663Bvd5Brain ventricular dilatation QTL 53.510.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)173219953486201342Rat
152023740Bp406Blood pressure QTL 4066.06arterial blood pressure trait (VT:2000000)172413612784432719Rat
152023737Bp405Blood pressure QTL 4055.06arterial blood pressure trait (VT:2000000)2413612784432719Rat
152023736Bp404Blood pressure QTL 4043.78arterial blood pressure trait (VT:2000000)172413612784432719Rat
724528Uae4Urinary albumin excretion QTL 44.90.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)173604553781045537Rat
2302365Gluco40Glucose level QTL 404.79blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)176456982086954580Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
11 1 10 115 32 31 5 53 5 2 121 78 4 101 27 62 26 13 13

Sequence


Ensembl Acc Id: ENSRNOT00000064609   ⟹   ENSRNOP00000062607
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1774,903,177 - 74,905,811 (+)Ensembl
Rnor_6.0 Ensembl1778,904,873 - 78,910,671 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000170659   ⟹   ENSRNOP00000108701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1779,813,106 - 79,818,448 (-)Ensembl
RefSeq Acc Id: NM_001126079   ⟹   NP_001119551
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81779,813,106 - 79,818,448 (-)NCBI
mRatBN7.21774,903,936 - 74,909,282 (-)NCBI
Rnor_6.01778,905,338 - 78,910,684 (-)NCBI
Rnor_5.01780,546,951 - 80,554,663 (-)NCBI
RGSC_v3.41786,022,618 - 86,027,750 (-)RGD
Celera1774,283,333 - 74,288,677 (-)RGD
Sequence:
RefSeq Acc Id: XM_006254269   ⟹   XP_006254331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81779,813,108 - 79,821,254 (-)NCBI
mRatBN7.21774,904,098 - 74,909,977 (-)NCBI
Rnor_6.01778,904,549 - 78,913,372 (-)NCBI
Rnor_5.01780,546,951 - 80,554,663 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001119551 (Get FASTA)   NCBI Sequence Viewer  
  XP_006254331 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL78700 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000108701
  ENSRNOP00000108701.1
RefSeq Acc Id: NP_001119551   ⟸   NM_001126079
- UniProtKB: A6JM23 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006254331   ⟸   XM_006254269
- Peptide Label: isoform X1
- UniProtKB: D3ZB36 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000062607   ⟸   ENSRNOT00000064609
Ensembl Acc Id: ENSRNOP00000108701   ⟸   ENSRNOT00000170659
Protein Domains
ACB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZB36-F1-model_v2 AlphaFold D3ZB36 1-88 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564164 AgrOrtholog
BioCyc Gene G2FUF-8641 BioCyc
Ensembl Genes ENSRNOG00000016480 Ensembl
  ENSRNOG00000071468 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000170659 ENTREZGENE
  ENSRNOT00000170659.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.80.10 UniProtKB/TrEMBL
InterPro Acyl-CoA-binding_protein UniProtKB/TrEMBL
  Acyl-CoA-binding_sf UniProtKB/TrEMBL
  FERM/acyl-CoA-bd_prot_sf UniProtKB/TrEMBL
KEGG Report rno:361277 UniProtKB/TrEMBL
NCBI Gene 361277 ENTREZGENE
PANTHER ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 7 UniProtKB/TrEMBL
  ACYL-COA-BINDING PROTEIN, ACBP UniProtKB/TrEMBL
Pfam ACBP UniProtKB/TrEMBL
PhenoGen Acbd7 PhenoGen
PRINTS ACOABINDINGP UniProtKB/TrEMBL
PROSITE ACB_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000016480 RatGTEx
  ENSRNOG00000071468 RatGTEx
RNAcentral URS00022B3CE6 RNACentral
Superfamily-SCOP Acyl-CoA binding protein UniProtKB/TrEMBL
UniProt A0ABK0LD72_RAT UniProtKB/TrEMBL
  A6JM23 ENTREZGENE, UniProtKB/TrEMBL
  D3ZB36 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-28 Acbd7  acyl-CoA binding domain containing 7  Acbd7  acyl-Coenzyme A binding domain containing 7  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-06 Acbd7  acyl-Coenzyme A binding domain containing 7  RGD1564164_predicted  similar to Acyl-CoA-binding protein (ACBP) (Diazepam binding inhibitor) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-10 RGD1564164_predicted  similar to Acyl-CoA-binding protein (ACBP) (Diazepam binding inhibitor) (predicted)    similar to Acyl-CoA-binding protein (ACBP) (Diazepam binding inhibitor) (DBI) (Endozepine) (EP) (predicted)  Name updated 1299863 APPROVED
2006-03-07 RGD1564164_predicted  similar to Acyl-CoA-binding protein (ACBP) (Diazepam binding inhibitor) (DBI) (Endozepine) (EP) (predicted)  LOC361277  similar to Acyl-CoA-binding protein (ACBP) (Diazepam binding inhibitor) (DBI) (Endozepine) (EP)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC361277  similar to Acyl-CoA-binding protein (ACBP) (Diazepam binding inhibitor) (DBI) (Endozepine) (EP)      Symbol and Name status set to provisional 70820 PROVISIONAL