Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nhsl2 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Nhsl2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of NHSL2 mRNA | CTD | PMID:36331819 | Nhsl2 | Rat | 1,2-dichloroethane | increases expression | ISO | Nhsl2 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of NHSL2 mRNA | CTD | PMID:28960355 | Nhsl2 | Rat | 17beta-estradiol | increases expression | ISO | NHSL2 (Homo sapiens) | 6480464 | Estradiol results in increased expression of NHSL2 mRNA | CTD | PMID:31614463 | Nhsl2 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Nhsl2 (Mus musculus) | 6480464 | 2,3',4,4',5-pentachlorobiphenyl results in increased expression of NHSL2 mRNA | CTD | PMID:31388691 | Nhsl2 | Rat | 2-palmitoylglycerol | increases expression | ISO | NHSL2 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of NHSL2 mRNA | CTD | PMID:37199045 | Nhsl2 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Nhsl2 (Mus musculus) | 6480464 | bisphenol S results in increased expression of NHSL2 mRNA | CTD | PMID:30951980 | Nhsl2 | Rat | aflatoxin B1 | increases methylation | ISO | NHSL2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of NHSL2 intron | CTD | PMID:30157460 | Nhsl2 | Rat | Aflatoxin B2 alpha | decreases methylation | ISO | NHSL2 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of NHSL2 intron | CTD | PMID:30157460 | Nhsl2 | Rat | arsane | affects methylation | ISO | NHSL2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of NHSL2 gene | CTD | PMID:25304211 | Nhsl2 | Rat | arsane | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nhsl2 | Rat | arsenic atom | affects methylation | ISO | NHSL2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of NHSL2 gene | CTD | PMID:25304211 | Nhsl2 | Rat | arsenic atom | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nhsl2 | Rat | benzo[a]pyrene | affects methylation | ISO | NHSL2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of NHSL2 exon; Benzo(a)pyrene affects the methylation of NHSL2 intron; Benzo(a)pyrene more ... | CTD | PMID:27901495|PMID:30157460 | Nhsl2 | Rat | benzo[a]pyrene | decreases methylation | ISO | Nhsl2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of NHSL2 intron | CTD | PMID:27901495 | Nhsl2 | Rat | benzo[e]pyrene | increases methylation | ISO | NHSL2 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of NHSL2 intron | CTD | PMID:30157460 | Nhsl2 | Rat | bisphenol A | increases expression | ISO | NHSL2 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of NHSL2 mRNA | CTD | PMID:27685785 | Nhsl2 | Rat | bisphenol A | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of NHSL2 gene | CTD | PMID:31601247 | Nhsl2 | Rat | bisphenol A | decreases methylation | ISO | NHSL2 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of NHSL2 gene | CTD | PMID:31601247 | Nhsl2 | Rat | bisphenol A | increases expression | ISO | Nhsl2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of NHSL2 mRNA | CTD | PMID:35598803 | Nhsl2 | Rat | bisphenol A | decreases expression | ISO | Nhsl2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of NHSL2 mRNA | CTD | PMID:39742910 | Nhsl2 | Rat | bisphenol F | increases expression | ISO | Nhsl2 (Mus musculus) | 6480464 | bisphenol F results in increased expression of NHSL2 mRNA | CTD | PMID:30951980 | Nhsl2 | Rat | butanal | decreases expression | ISO | NHSL2 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of NHSL2 mRNA | CTD | PMID:26079696 | Nhsl2 | Rat | Butylbenzyl phthalate | decreases methylation | ISO | Nhsl2 (Mus musculus) | 6480464 | butylbenzyl phthalate results in decreased methylation of NHSL2 intron | CTD | PMID:28392331 | Nhsl2 | Rat | cadmium atom | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NHSL2 more ... | CTD | PMID:35301059 | Nhsl2 | Rat | cadmium dichloride | increases expression | ISO | NHSL2 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of NHSL2 mRNA | CTD | PMID:38568856 | Nhsl2 | Rat | cadmium dichloride | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of NHSL2 more ... | CTD | PMID:35301059 | Nhsl2 | Rat | carbon nanotube | decreases expression | ISO | Nhsl2 (Mus musculus) | 6480464 | Nanotubes, Carbon analog results in decreased expression of NHSL2 mRNA | CTD | PMID:25554681 | Nhsl2 | Rat | clofibrate | increases expression | ISO | Nhsl2 (Mus musculus) | 6480464 | Clofibrate results in increased expression of NHSL2 mRNA | CTD | PMID:17585979 | Nhsl2 | Rat | DDT | increases methylation | EXP | | 6480464 | DDT results in increased methylation of NHSL2 gene | CTD | PMID:30207508 | Nhsl2 | Rat | Dibutyl phosphate | affects expression | ISO | NHSL2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of NHSL2 mRNA | CTD | PMID:37042841 | Nhsl2 | Rat | diclofenac | increases expression | ISO | Nhsl2 (Mus musculus) | 6480464 | Diclofenac results in increased expression of NHSL2 mRNA | CTD | PMID:35537566 | Nhsl2 | Rat | doxorubicin | decreases expression | ISO | NHSL2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of NHSL2 mRNA | CTD | PMID:29803840 | Nhsl2 | Rat | ethanol | affects splicing | ISO | Nhsl2 (Mus musculus) | 6480464 | Ethanol affects the splicing of NHSL2 mRNA | CTD | PMID:30319688 | Nhsl2 | Rat | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of NHSL2 mRNA | CTD | PMID:30307764 | Nhsl2 | Rat | folic acid | decreases expression | ISO | Nhsl2 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of NHSL2 mRNA | CTD | PMID:25629700 | Nhsl2 | Rat | fulvestrant | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of NHSL2 gene | CTD | PMID:31601247 | Nhsl2 | Rat | GW 4064 | increases expression | ISO | Nhsl2 (Mus musculus) | 6480464 | GW 4064 results in increased expression of NHSL2 mRNA | CTD | PMID:26655953 | Nhsl2 | Rat | lipopolysaccharide | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | S-(1,2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NHSL2 mRNA] | CTD | PMID:35811015 | Nhsl2 | Rat | lipopolysaccharide | increases expression | ISO | NHSL2 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of NHSL2 mRNA | CTD | PMID:35811015 | Nhsl2 | Rat | manganese atom | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nhsl2 | Rat | manganese(0) | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nhsl2 | Rat | manganese(II) chloride | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:39836092 | Nhsl2 | Rat | methapyrilene | increases methylation | ISO | NHSL2 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of NHSL2 intron | CTD | PMID:30157460 | Nhsl2 | Rat | nickel atom | decreases expression | ISO | NHSL2 (Homo sapiens) | 6480464 | Nickel results in decreased expression of NHSL2 mRNA | CTD | PMID:23195993 | Nhsl2 | Rat | okadaic acid | increases expression | ISO | NHSL2 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of NHSL2 mRNA | CTD | PMID:38832940 | Nhsl2 | Rat | panobinostat | affects expression | ISO | NHSL2 (Homo sapiens) | 6480464 | panobinostat affects the expression of NHSL2 mRNA | CTD | PMID:26733615 | Nhsl2 | Rat | panobinostat | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | (+)-JQ1 compound promotes the reaction [panobinostat affects the expression of NHSL2 mRNA]; panobinostat promotes the more ... | CTD | PMID:26733615 | Nhsl2 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Nhsl2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of NHSL2 mRNA | CTD | PMID:36331819 | Nhsl2 | Rat | rotenone | increases expression | ISO | Nhsl2 (Mus musculus) | 6480464 | Rotenone results in increased expression of NHSL2 mRNA | CTD | PMID:32937126 | Nhsl2 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | S-(1,2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NHSL2 mRNA] | CTD | PMID:35811015 | Nhsl2 | Rat | sodium arsenite | decreases expression | ISO | Nhsl2 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of NHSL2 mRNA | CTD | PMID:39515575 | Nhsl2 | Rat | sodium arsenite | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased more ... | CTD | PMID:33939924|PMID:39836092 | Nhsl2 | Rat | sotorasib | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NHSL2 mRNA | CTD | PMID:36139627 | Nhsl2 | Rat | titanium dioxide | increases methylation | ISO | Nhsl2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of NHSL2 gene | CTD | PMID:35295148 | Nhsl2 | Rat | trametinib | multiple interactions | ISO | NHSL2 (Homo sapiens) | 6480464 | [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of NHSL2 mRNA | CTD | PMID:36139627 | Nhsl2 | Rat | triphenyl phosphate | affects expression | ISO | NHSL2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of NHSL2 mRNA | CTD | PMID:37042841 | Nhsl2 | Rat | trovafloxacin | decreases expression | ISO | Nhsl2 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of NHSL2 mRNA | CTD | PMID:35537566 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















