Vom2r4 (vomeronasal 2 receptor, 4) - Rat Genome Database

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Gene: Vom2r4 (vomeronasal 2 receptor, 4) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Vom2r4
Name: vomeronasal 2 receptor, 4
RGD ID: 1564110
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane; INTERACTS WITH acrylamide; cadmium dichloride; paraquat.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC108352192; LOC308248; RGD1564110; similar to putative pheromone receptor; vomeronasal 2 receptor 4; vomeronasal type-2 receptor 116-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr812,874,499 - 2,889,566 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl12,874,499 - 2,889,566 (-)EnsemblGRCr8
mRatBN7.21226,465 - 241,532 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1226,341 - 272,253 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1575,935 - 590,998 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.016,576,316 - 6,591,379 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01858,021 - 873,084 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd12,831,047 - 2,846,110 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive12,032,497 - 2,047,560 (-)NCBILyon_Normotensive
Lyon_Hypertensive11,024,532 - 1,039,595 (-)NCBILyon_Hypertensive
F344_StmMcwi11,702,343 - 1,717,406 (-)NCBIF344_StmMcwi
Rnor_6.01714,270 - 719,690 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl10111,716,966 - 111,735,354 (+)Ensemblrn6Rnor6.0
Rnor_5.01703,155 - 708,575 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.411,134,798 - 1,149,865 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera16,347 - 11,772 (-)NCBICelera
Cytogenetic Map1p13NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17382427  


Genomics

Variants

.
Variants in Vom2r4
62 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:173
Count of miRNA genes:82
Interacting mature miRNAs:87
Transcripts:ENSRNOT00000043877, ENSRNOT00000048946, ENSRNOT00000070942, ENSRNOT00000071037, ENSRNOT00000072076, ENSRNOT00000072232, ENSRNOT00000073032, ENSRNOT00000074130, ENSRNOT00000074402, ENSRNOT00000074598
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600360Mcs16Mammary carcinoma susceptibility QTL 162.4mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1126564886Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)1143965634Rat
1354647Despr8Despair related QTL 80.0000341locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1126564886Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)1134184556Rat
1300170Rf6Renal function QTL 63.14renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)1128483164Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
3 4 26 18 15 1 1 1 41 19 13 18 59 14 5 5

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001099458 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000044669   ⟹   ENSRNOP00000043136
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1226,341 - 272,253 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000070942   ⟹   ENSRNOP00000064131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl10111,716,966 - 111,735,354 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099894   ⟹   ENSRNOP00000090453
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1226,341 - 241,622 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113739   ⟹   ENSRNOP00000081115
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1226,434 - 241,622 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000124032   ⟹   ENSRNOP00000103607
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl12,874,499 - 2,889,566 (-)Ensembl
RefSeq Acc Id: NM_001099458   ⟹   NP_001092928
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr812,874,499 - 2,889,566 (-)NCBI
mRatBN7.21226,465 - 241,532 (-)NCBI
Dahl_SR_JrHsd12,831,047 - 2,846,110 (-)NCBI
Lyon_Normotensive12,032,497 - 2,047,560 (-)NCBI
Lyon_Hypertensive11,024,532 - 1,039,595 (-)NCBI
F344_StmMcwi11,702,343 - 1,717,406 (-)NCBI
Rnor_6.01714,270 - 719,690 (-)NCBI
Rnor_5.01703,155 - 708,575 (-)NCBI
RGSC_v3.411,134,798 - 1,149,865 (-)RGD
Celera16,347 - 11,772 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001092928 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000103607
  ENSRNOP00000103607.1
RefSeq Acc Id: NP_001092928   ⟸   NM_001099458
- Peptide Label: precursor
- UniProtKB: A0A8I6AEC9 (UniProtKB/TrEMBL),   A0A8I6AFS9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064131   ⟸   ENSRNOT00000070942
Ensembl Acc Id: ENSRNOP00000081115   ⟸   ENSRNOT00000113739
Ensembl Acc Id: ENSRNOP00000043136   ⟸   ENSRNOT00000044669
Ensembl Acc Id: ENSRNOP00000090453   ⟸   ENSRNOT00000099894
Ensembl Acc Id: ENSRNOP00000103607   ⟸   ENSRNOT00000124032

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R454-F1-model_v2 AlphaFold M0R454 1-838 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564110 AgrOrtholog
BioCyc Gene G2FUF-62517 BioCyc
Ensembl Genes ENSRNOG00000047388 Ensembl
  ENSRNOG00000069644 Ensembl
  ENSRNOG00000084257 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000124032 ENTREZGENE
  ENSRNOT00000124032.1 UniProtKB/TrEMBL
NCBI Gene 308248 ENTREZGENE
PhenoGen Vom2r4 PhenoGen
RatGTEx ENSRNOG00000047388 RatGTEx
  ENSRNOG00000069644 RatGTEx
  ENSRNOG00000084257 RatGTEx
UniProt A0A8I6AEC9 ENTREZGENE
  A0A8I6AFS9 ENTREZGENE
  A0ABK0LKX1_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Vom2r4  vomeronasal 2 receptor, 4  LOC108352192  vomeronasal type-2 receptor 116-like  Data merged from RGD:11397307 737654 PROVISIONAL
2016-08-02 LOC108352192  vomeronasal type-2 receptor 116-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-07-23 Vom2r4  vomeronasal 2 receptor, 4  RGD1564110  similar to putative pheromone receptor   Symbol and Name updated 1299863 APPROVED
2008-04-30 RGD1564110  similar to putative pheromone receptor   RGD1564110_predicted  similar to putative pheromone receptor (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1564110_predicted  similar to putative pheromone receptor (predicted)  LOC308248  similar to putative pheromone receptor  Symbol and Name status set to approved 1299863 APPROVED