Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Vash2 | Rat | 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane | multiple interactions | EXP | | 6480464 | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of VASH2 mRNA]; 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the more ... | CTD | PMID:19414516 | Vash2 | Rat | 1,2-dichloroethane | decreases expression | ISO | Vash2 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of VASH2 mRNA | CTD | PMID:28960355 | Vash2 | Rat | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of VASH2 mRNA | CTD | PMID:30723492 | Vash2 | Rat | 17beta-estradiol | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of VASH2 mRNA | CTD | PMID:30165855 | Vash2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of VASH2 mRNA | CTD | PMID:33387578 | Vash2 | Rat | 2,4-D | multiple interactions | ISO | Vash2 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ... | CTD | PMID:37567420 | Vash2 | Rat | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | affects expression | ISO | Vash2 (Mus musculus) | 6480464 | 2,2',4,4',5-brominated diphenyl ether affects the expression of VASH2 mRNA | CTD | PMID:38648751 | Vash2 | Rat | 3',5'-cyclic AMP | multiple interactions | EXP | | 6480464 | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of VASH2 mRNA] | CTD | PMID:19414516 | Vash2 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Vash2 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of VASH2 exon | CTD | PMID:33297965 | Vash2 | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Vash2 (Mus musculus) | 6480464 | bisphenol S affects the methylation of VASH2 gene | CTD | PMID:31683443 | Vash2 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | VASH2 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of VASH2 gene | CTD | PMID:31601247 | Vash2 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of VASH2 mRNA | CTD | PMID:24780913|PMID:30047161 | Vash2 | Rat | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of VASH2 mRNA | CTD | PMID:28959563 | Vash2 | Rat | aldehydo-D-glucose | multiple interactions | ISO | Vash2 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ... | CTD | PMID:37567420 | Vash2 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of VASH2 mRNA | CTD | PMID:35163327 | Vash2 | Rat | alpha-Zearalanol | decreases expression | EXP | | 6480464 | Zeranol results in decreased expression of VASH2 mRNA | CTD | PMID:35163327 | Vash2 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of VASH2 mRNA | CTD | PMID:30047161 | Vash2 | Rat | arsenite(3-) | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to VASH2 mRNA] | CTD | PMID:32406909 | Vash2 | Rat | atrazine | decreases expression | ISO | VASH2 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of VASH2 mRNA | CTD | PMID:22378314 | Vash2 | Rat | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of VASH2 mRNA | CTD | PMID:36841081 | Vash2 | Rat | belinostat | increases expression | ISO | VASH2 (Homo sapiens) | 6480464 | belinostat results in increased expression of VASH2 mRNA | CTD | PMID:26272509 | Vash2 | Rat | belinostat | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Vash2 | Rat | benzo[a]pyrene | affects methylation | ISO | VASH2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of VASH2 exon | CTD | PMID:30157460 | Vash2 | Rat | benzo[a]pyrene | decreases expression | ISO | VASH2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of VASH2 mRNA | CTD | PMID:32234424 | Vash2 | Rat | benzo[a]pyrene | decreases methylation | ISO | VASH2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of VASH2 5' UTR; Benzo(a)pyrene results in decreased methylation of more ... | CTD | PMID:27901495 | Vash2 | Rat | bis(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in increased expression of VASH2 mRNA | CTD | PMID:33789034 | Vash2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of VASH2 mRNA | CTD | PMID:25181051 | Vash2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of VASH2 mRNA | CTD | PMID:30816183|PMID:34947998 | Vash2 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of VASH2 gene | CTD | PMID:28505145 | Vash2 | Rat | bisphenol A | increases expression | ISO | VASH2 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of VASH2 mRNA | CTD | PMID:27685785 | Vash2 | Rat | butanal | decreases expression | ISO | VASH2 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of VASH2 mRNA | CTD | PMID:26079696 | Vash2 | Rat | carbamazepine | affects expression | ISO | VASH2 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of VASH2 mRNA | CTD | PMID:25979313 | Vash2 | Rat | clotrimazole | increases expression | EXP | | 6480464 | Clotrimazole results in increased expression of VASH2 mRNA | CTD | PMID:30047161 | Vash2 | Rat | copper atom | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of VASH2 mRNA | CTD | PMID:20971185 | Vash2 | Rat | copper(0) | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of VASH2 mRNA | CTD | PMID:20971185 | Vash2 | Rat | D-glucose | multiple interactions | ISO | Vash2 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ... | CTD | PMID:37567420 | Vash2 | Rat | dexamethasone | decreases expression | ISO | VASH2 (Homo sapiens) | 6480464 | Dexamethasone results in decreased expression of VASH2 mRNA | CTD | PMID:25047013 | Vash2 | Rat | diallyl disulfide | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | diallyl disulfide inhibits the reaction [tobacco tar analog results in decreased expression of VASH2 mRNA] | CTD | PMID:36758788 | Vash2 | Rat | Dibutyl phosphate | affects expression | ISO | VASH2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of VASH2 mRNA | CTD | PMID:37042841 | Vash2 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of VASH2 mRNA | CTD | PMID:21266533 | Vash2 | Rat | disodium selenite | decreases expression | ISO | VASH2 (Homo sapiens) | 6480464 | Sodium Selenite results in decreased expression of VASH2 mRNA | CTD | PMID:18175754 | Vash2 | Rat | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of VASH2 mRNA | CTD | PMID:25152437 | Vash2 | Rat | dorsomorphin | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Vash2 | Rat | entinostat | increases expression | ISO | VASH2 (Homo sapiens) | 6480464 | entinostat results in increased expression of VASH2 mRNA | CTD | PMID:26272509 | Vash2 | Rat | entinostat | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Vash2 | Rat | fructose | multiple interactions | ISO | Vash2 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ... | CTD | PMID:37567420 | Vash2 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of VASH2 mRNA | CTD | PMID:33387578 | Vash2 | Rat | glucose | multiple interactions | ISO | Vash2 (Mus musculus) | 6480464 | [lard co-treated with Cholesterol, Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose more ... | CTD | PMID:37567420 | Vash2 | Rat | lipopolysaccharide | increases expression | ISO | VASH2 (Homo sapiens) | 6480464 | Lipopolysaccharides results in increased expression of VASH2 mRNA | CTD | PMID:35811015 | Vash2 | Rat | lipopolysaccharide | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of VASH2 mRNA | CTD | PMID:35811015 | Vash2 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of VASH2 mRNA | CTD | PMID:30047161 | Vash2 | Rat | okadaic acid | decreases expression | ISO | VASH2 (Homo sapiens) | 6480464 | Okadaic Acid results in decreased expression of VASH2 mRNA | CTD | PMID:38832940 | Vash2 | Rat | panobinostat | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Vash2 | Rat | panobinostat | increases expression | ISO | VASH2 (Homo sapiens) | 6480464 | panobinostat results in increased expression of VASH2 mRNA | CTD | PMID:26272509 | Vash2 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of VASH2 mRNA | CTD | PMID:33387578 | Vash2 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of VASH2 mRNA | CTD | PMID:35163327 | Vash2 | Rat | pirinixic acid | increases expression | ISO | Vash2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of VASH2 mRNA | CTD | PMID:20813756 | Vash2 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of VASH2 mRNA | CTD | PMID:30047161 | Vash2 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | [S-(1,2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of VASH2 mRNA | CTD | PMID:35811015 | Vash2 | Rat | SB 431542 | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Vash2 | Rat | silicon dioxide | decreases expression | ISO | VASH2 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of VASH2 mRNA | CTD | PMID:25895662 | Vash2 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of VASH2 mRNA | CTD | PMID:30047161 | Vash2 | Rat | sulforaphane | decreases expression | ISO | VASH2 (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of VASH2 mRNA | CTD | PMID:31838189 | Vash2 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of VASH2 mRNA | CTD | PMID:33387578 | Vash2 | Rat | thiram | increases expression | ISO | VASH2 (Homo sapiens) | 6480464 | Thiram results in increased expression of VASH2 mRNA | CTD | PMID:38568856 | Vash2 | Rat | titanium dioxide | increases methylation | ISO | Vash2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of VASH2 promoter | CTD | PMID:35295148 | Vash2 | Rat | titanium dioxide | decreases methylation | ISO | Vash2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of VASH2 gene | CTD | PMID:35295148 | Vash2 | Rat | trichostatin A | increases expression | ISO | VASH2 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of VASH2 mRNA | CTD | PMID:24935251|PMID:26272509 | Vash2 | Rat | trichostatin A | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Vash2 | Rat | triptonide | decreases expression | ISO | Vash2 (Mus musculus) | 6480464 | triptonide results in decreased expression of VASH2 mRNA | CTD | PMID:33045310 | Vash2 | Rat | urethane | decreases expression | ISO | VASH2 (Homo sapiens) | 6480464 | Urethane results in decreased expression of VASH2 mRNA | CTD | PMID:28818685 | Vash2 | Rat | valproic acid | affects expression | ISO | Vash2 (Mus musculus) | 6480464 | Valproic Acid affects the expression of VASH2 mRNA | CTD | PMID:17292431 | Vash2 | Rat | valproic acid | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased more ... | CTD | PMID:27188386 | Vash2 | Rat | valproic acid | increases expression | ISO | VASH2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of VASH2 mRNA | CTD | PMID:23179753|PMID:24383497|PMID:24935251|PMID:26272509 | Vash2 | Rat | valproic acid | affects expression | ISO | VASH2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of VASH2 mRNA | CTD | PMID:25979313 | Vash2 | Rat | vorinostat | increases expression | ISO | VASH2 (Homo sapiens) | 6480464 | vorinostat results in increased expression of VASH2 mRNA | CTD | PMID:26272509 | Vash2 | Rat | vorinostat | multiple interactions | ISO | VASH2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression more ... | CTD | PMID:27188386 | Vash2 | Rat | zinc atom | decreases expression | ISO | VASH2 (Homo sapiens) | 6480464 | Zinc deficiency results in decreased expression of VASH2 mRNA | CTD | PMID:18356318 | Vash2 | Rat | zinc(0) | decreases expression | ISO | VASH2 (Homo sapiens) | 6480464 | Zinc deficiency results in decreased expression of VASH2 mRNA | CTD | PMID:18356318 | | 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