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Gene: Dcaf12l1 (DDB1 and CUL4 associated factor 12-like 1) Rattus norvegicus

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Symbol:

Dcaf12l1

Name:

DDB1 and CUL4 associated factor 12-like 1

RGD ID:

1563873

Description:

Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Orthologous to human DCAF12L1 (DDB1 and CUL4 associated factor 12 like 1); INTERACTS WITH 17beta-estradiol 3-benzoate; 3,3',4,4',5-pentachlorobiphenyl; 3,7-dihydropurine-6-thione.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Dcaf12; DDB1 and CUL4 associated factor 12; DDB1- and CUL4-associated factor 12-like protein 1; LOC313296; RGD1563873; similar to WD repeat domain 40B; WD repeat domain 40B; Wdr40b

RGD Orthologs

Human

Mouse

Bonobo

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	128,572,969 - 128,576,588 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	128,572,811 - 128,577,222 (-)	Ensembl				GRCr8
mRatBN7.2	X	123,695,286 - 123,698,905 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	123,695,286 - 123,698,905 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	125,792,640 - 125,796,263 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	129,313,989 - 129,317,610 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	126,876,747 - 126,880,370 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	131,340,045 - 131,344,038 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	131,340,045 - 131,343,853 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	131,415,634 - 131,419,608 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	175,822 - 179,442 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	122,751,698 - 122,755,317 (-)	NCBI		Celera
Cytogenetic Map	X	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

spermatogenic failure 57 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

17beta-estradiol 3-benzoate (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,7-dihydropurine-6-thione (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

8-Br-cAMP (ISO)

aflatoxin B1 (EXP)

allopurinol (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

choline (ISO)

copper(II) sulfate (ISO)

dibutyl phthalate (ISO)

diethyl phthalate (ISO)

diisobutyl phthalate (ISO)

diisononyl phthalate (ISO)

dorsomorphin (ISO)

folic acid (ISO)

inulin (ISO)

L-methionine (ISO)

maneb (ISO)

mercaptopurine (EXP)

paraquat (ISO)

perfluorooctane-1-sulfonic acid (ISO)

phenylmercury acetate (ISO)

pioglitazone (ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

propiconazole (ISO)

purine-6-thiol (EXP)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenate (ISO)

Theaflavin 3,3'-digallate (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

valproic acid (ISO)

XL147 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

Cul4-RING E3 ubiquitin ligase complex (IBA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data

Dcaf12l1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	128,572,969 - 128,576,588 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	X	128,572,811 - 128,577,222 (-)	Ensembl				GRCr8
mRatBN7.2	X	123,695,286 - 123,698,905 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	123,695,286 - 123,698,905 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	X	125,792,640 - 125,796,263 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	129,313,989 - 129,317,610 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	126,876,747 - 126,880,370 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	131,340,045 - 131,344,038 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	131,340,045 - 131,343,853 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	X	131,415,634 - 131,419,608 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	X	175,822 - 179,442 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	X	122,751,698 - 122,755,317 (-)	NCBI		Celera
Cytogenetic Map	X	q35	NCBI

DCAF12L1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	126,549,383 - 126,552,814 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	126,549,383 - 126,552,814 (-)	Ensembl			hg38	GRCh38
GRCh37	X	125,683,366 - 125,686,797 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	125,511,050 - 125,514,515 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	X	125,408,903 - 125,412,369	NCBI
Celera	X	126,067,577 - 126,071,053 (-)	NCBI		Celera
Cytogenetic Map	X	q25	NCBI
HuRef	X	115,062,799 - 115,065,469 (-)	NCBI		HuRef
CHM1_1	X	125,594,290 - 125,597,766 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	X	124,862,123 - 124,865,554 (-)	NCBI		T2T-CHM13v2.0

Dcaf12l1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	43,875,444 - 43,879,074 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	43,875,447 - 43,879,074 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	X	44,786,567 - 44,790,197 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	44,786,570 - 44,790,197 (-)	Ensembl			mm10	GRCm38
MGSCv37	X	42,139,749 - 42,143,328 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	X	41,031,197 - 41,034,778 (-)	NCBI		MGSCv36	mm8
Celera	X	32,324,653 - 32,328,232 (-)	NCBI		Celera
Cytogenetic Map	X	A4	NCBI
cM Map	X	24.0	NCBI

DCAF12L1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	126,021,214 - 126,024,727 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	126,024,826 - 126,028,339 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	115,730,337 - 115,733,781 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	125,907,275 - 125,910,756 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	125,909,106 - 125,910,497 (-)	Ensembl			panPan2	panpan1.1

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	367
Count of miRNA genes:	226
Interacting mature miRNAs:	269
Transcripts:	ENSRNOT00000038653
Prediction methods:	Miranda, Pita, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598872	Memor14	Memory QTL 14	4.5		exploratory behavior trait (VT:0010471)	difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	97528096	142528096	Rat
1598856	Memor1	Memory QTL 1	1.9		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	X	120028026	141353710	Rat
1598809	Memor15	Memory QTL 15	4.4		exploratory behavior trait (VT:0010471)	difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	120028026	141353710	Rat
738025	Stresp3	Stress response QTL 3	4.61	0.0066	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	105359969	157758123	Rat
10059603	Bw174	Body weight QTL 174	3.4	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	X	118973754	157758123	Rat
2302047	Pia34	Pristane induced arthritis QTL 34	5.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	19	96916163	141916163	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
13	10	62	152	82	78	50	58	50	5	290	148	11	126	71	92	28	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001107941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006257515	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008773519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000038653 ⟹ ENSRNOP00000038146

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	128,572,811 - 128,577,222 (-)	Ensembl
mRatBN7.2 Ensembl	X	123,695,286 - 123,698,905 (-)	Ensembl
Rnor_6.0 Ensembl	X	131,340,045 - 131,343,853 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000146907 ⟹ ENSRNOP00000105968

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	X	128,572,966 - 128,577,222 (-)	Ensembl

RefSeq Acc Id:

NM_001107941 ⟹ NP_001101411

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	128,572,969 - 128,576,588 (-)	NCBI
mRatBN7.2	X	123,695,286 - 123,698,905 (-)	NCBI
Rnor_6.0	X	131,340,045 - 131,343,853 (-)	NCBI
Rnor_5.0	X	131,415,634 - 131,419,608 (-)	NCBI
RGSC_v3.4	X	175,822 - 179,442 (+)	RGD
Celera	X	122,751,698 - 122,755,317 (-)	RGD

Sequence:

show sequence

CACTCCTGTGCTGGCAGGCAGCAGTCTCCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
CTCTCTCTCTCTCTAGCCGCATCTTCGGCCCCAGCACCGATCGTCCCGAGCTCGCTCGGCTCTT
TCCGCCCGACCTCGCGTTGTTCGCCGGGTCACGCCGCCACCACCTCCTTTGCCGCCAAGGCTCT
CCGGACTCGGTAGGCTCCCCGCTGATCAGTCGATCGCTCTCTCGCTTGCTCCAAAGCCTCCATC
TCCCAGCGATATCATGCGTCAGGCCGACTCTCAGACGCAGCCCTCTCCCGCAGAGCAGGAGATG
CCGCAGCCTGCAGGGCCCTCCAACAGCTCGCCGCCCACCATGGGCCCGCAGCAAACAGGTAGCA
GGAAGCGGAAAGCCGCCGAGGTCGATCAGGGCGCCGGGACTTCTTCGTCGCCAGGCCCTGCAGC
GGCGATGGCGACAGTTGGGGCGGGCAATGCAGAGGGGTCCTTGATGCTGACCAAGAGGCCGCGG
CGGCCCATAGCTCACCTCTCCATGGTGAACTACCTGAAGGGCCGCGCGCTAGGCGCCGATGGCC
ACCCGGGGTTCGCAGGCTTCGAGGGTGATCTGCGCAGTTACGGGGTCCTCAGGCTGCCCGAGCT
GCTGAGGGAGCGCCAGCTGACCCTGGGCCCACTCAACAAGGTGTTCGCATCGCAGTGGCTCAAT
GCCAGGCAGGTGGTGTGTGGCACCAAGTGCAACACTCTCTTCGTGGTTGATGTCAAAACCGACC
ACATCATGCGCATTCCTCTGATGCGCGACAGGGTGCCCGACCTGTCCCGTGGCCCGCCCTCCTG
TGGCATTCATGCTGTGGAGCTGAATCCCTCCAAGACCCTCTTGGCCACTGGAGGTGAAAATCCC
AACAGCCTGGCAGTATACCAGTTGCCCACTCTGGATCCGGTGTGCCTAGGAGATTGCCAAGGCC
ACAGGGACTGGATCTTTGCCATTGCATGGATGAGTGACACCGTGGCTGTGAGTGGTTCCCGCGA
TGGCACCGTGGCGCTTTGGAAGGTGGATCCTGACATGTTCAATGGCAGCATTGCTTGGCACAAG
GATGCAGGGCTCCCTGTGTATGCTCACATCAGTCCTACAGATATGGAGGCCATCCCCAAAGCCA
CTACCAATCCAGGTAACCGCAAAGTGCGAGCACTCGCCTTCAGCAACAAAAACCAGGAGCTGGG
GGCTGTGTCCCTGGATGGCTACTTCCACCTGTGGAAAGCCCGAAGCTCCCTGTCCAGGCTGCTG
TCCCTGAGGCTGCCCTACTGCCGTGAGAACGTGTGTCTCACCTATTGTGATGAGTTTTCCCTCT
ATGCTGTGGGTTCCCAGTCTCACGTTTCCTTCCTGGATCTCCGCCAAGGCCAGCAGAACATCCC
TCCACTGTGCTCCAGAGAGGGAGGCACCGGTGTGCGTTCTCTGAGTGTCCACCAGCATATTGTC
ACCGTGGGAACAGGCCATGGTTCTCTGCTCTTCTATGATATACGTGCTCAGAAGTTCCTTGAGG
AAAGATCCGCGGCCAATCCAGACATGTTTCCTGTGCCCTCTGGAAGGAAGCTCAAGCTCACCTG
TGGCAGCGGCTGGATCAACCAGGATGATCTCCTCGAGAATTATGTTGCTGGTGTAGAAGATTTC
CCCAACGCACTCTACACCCACTGCTACAACTGGCCGGAAATGAAGCTCTTCGTAGGAGGGGGAC
CACTGGCCTCAGGCCTCCATGGCAACTACGCAGGCCTCTGGAGCTAAGAGTGATGCGACTCCTT
CTCAAAGTGGAACTGGCCCAGAGTATCCAGTGCGCTTCTCAGTAGAGAGAAAGAGATGGAACCT
TCAGAAGTTGGCTTTGAGAATTTTCTGGACTTCCCCACCATTCTTTGGACTTTCCATGCATATA
CTTTCCACTAATTCTTGCTGTGTTGTTTTCGAGTGAGTGATCCATGTAGTCTATTATGGAAAAA
AATCCTGTTATAATGTTAGAATTGTATAAGTGTTGTGTTACTATTATTAGCAGTTTTAAAGCTA
TTGTTTTTGGTTTTCATCTCGTGTGATATATTTAGAATATTTTCTAATAAACAGAGTTTGAACA
TCTGTTCTGGAGCACTAATCATAGTTTTGTAGCATTGGTCCAATTGTAAAAAAAAAAGAAAAAA
AAAACATTCCATGTTCCAGTTGCCTACTTTTGGAAATATGTCACTCATGAATTGTGATCATGGT
GTATGTATATAGTTTGTATGTTGTTGGTGCAAAACTCACTTTTCTAAAAAGTTTATTATGTGGA
AATAATTGCATAGAATCTTGTGTTTATATCAAAATCTCAGCTGACAAGGATGGTTTAGGTAGTC
AAGTATTCTGCTCATTTGAGTGTGGAAGATGAATCCAAAAATCAGTGTTTTTCTTTTGAGCCTT
ATTTTAGTTTTTATGCTCTGTCTTCATATTTATCAAAGAATGTACTTGTTTTCACTTCTTGCCT
TAGTACTATCAAGACTTGTGGATATATTTGAATGCTGTCATTTGAGTAAATTGCACAGAGTTTC
AGTGCCATCATTCGATGCAGGGATATTAAGTACATAAATGTAGAATGTATGGCAGACAGGGCAG
GAAATACACTGCTCTAAGGTATAGACTGGATATTTTTGCTGTTGCTATTTTTAATACCAAATGT
TATATTTGAGCATATTTTAAACTTTCAAAATCTGCTTATGAGTTACGTTGGAAGGAAAAAAAGT
CGAAGGAGAAAGTATGAGCCCATCCAGCTCACTGTGAGAGAAACTCCCCATCTTTGTAAGCTCC
AAATGTTTTATTTTGTGAACTTGAAAGATTCATACTTAAAGTAGAATAGATATGTTACTAAAAC
CTCTGGTTCTATGCCTTTAAATATGATAATATAGGATCGTGACAATGCAGTATAATTTTCAAGT
AGAGGGGCTGGGGATGAAAGAACTTAAAGTTCAGATTAAAGTTCGGATAAACAGAGATAATGGG
ATGCTGTGCGTAAGGATTGGTTTTTTCCCTAGGTGAGAAGACCAAAACTGAGAAAGGAGCCGGG
CCTTGTTCAAAGCTGGCTAGGACGTGTTTACCGTGGATTGGTATTGGGTCATGTTTCCTTTTTC
TTAAACATCAAACATGTATTTTGCCTTGGTGTTGACACACTACATGTTGTTCAGGACTAAACCT
AAATTGTTGAGAGGATCTAAAGGTGAGTCAAGAATACACAGTGGTCAGATTTTCTGTTTGTAAA
GATTATGCAGGTCTATTTCGTAGAATTACAAAGTTTTGCAACTTATCTGTGCATTTTCTTGCTT
GCATGTATGTTTCTCTCTCTGCTGCCAATGATTTCAGAGCAGAGGCTGTAAACTGCCATCTTTT
CTTTCTTTCTTTGTATCCTAAGGCCAAACAAAGGCAATCAGTGATTATTGGACGATTTTTGTTT
TGCCAATGGAAACCTGCACTTGAACTTGTAATAAATATTTGCTGTTGCATAATAAAGAACCTTG
TTCTGTGTTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001101411	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM10895	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000038146
	ENSRNOP00000038146.3
	ENSRNOP00000105968.1

RefSeq Acc Id:

NP_001101411 ⟸ NM_001107941

- UniProtKB:

D4ABX0 (UniProtKB/TrEMBL), A6JMN3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRQADSQTQPSPAEQEMPQPAGPSNSSPPTMGPQQTGSRKRKAAEVDQGAGTSSSPGPAAAMAT
VGAGNAEGSLMLTKRPRRPIAHLSMVNYLKGRALGADGHPGFAGFEGDLRSYGVLRLPELLRER
QLTLGPLNKVFASQWLNARQVVCGTKCNTLFVVDVKTDHIMRIPLMRDRVPDLSRGPPSCGIHA
VELNPSKTLLATGGENPNSLAVYQLPTLDPVCLGDCQGHRDWIFAIAWMSDTVAVSGSRDGTVA
LWKVDPDMFNGSIAWHKDAGLPVYAHISPTDMEAIPKATTNPGNRKVRALAFSNKNQELGAVSL
DGYFHLWKARSSLSRLLSLRLPYCRENVCLTYCDEFSLYAVGSQSHVSFLDLRQGQQNIPPLCS
REGGTGVRSLSVHQHIVTVGTGHGSLLFYDIRAQKFLEERSAANPDMFPVPSGRKLKLTCGSGW
INQDDLLENYVAGVEDFPNALYTHCYNWPEMKLFVGGGPLASGLHGNYAGLWS

hide sequence

Ensembl Acc Id:

ENSRNOP00000038146 ⟸ ENSRNOT00000038653

Ensembl Acc Id:

ENSRNOP00000105968 ⟸ ENSRNOT00000146907

Protein Domains

DDB1- and CUL4-associated factor 12 beta-propeller

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4ABX0-F1-model_v2	AlphaFold	D4ABX0	1-501	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563873	AgrOrtholog
BioCyc Gene	G2FUF-1211	BioCyc
Ensembl Genes	ENSRNOG00000023458	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000038653	ENTREZGENE
	ENSRNOT00000038653.6	UniProtKB/TrEMBL
	ENSRNOT00000146907.1	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.10	UniProtKB/TrEMBL
InterPro	Beta-prop_DCAF12	UniProtKB/TrEMBL
	DCAF12	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom	UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:313296	UniProtKB/TrEMBL
NCBI Gene	313296	ENTREZGENE
PANTHER	DDB1- AND CUL4-ASSOCIATED FACTOR 12-LIKE PROTEIN 2	UniProtKB/TrEMBL
	DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED	UniProtKB/TrEMBL
Pfam	Beta-prop_DCAF12	UniProtKB/TrEMBL
PhenoGen	Dcaf12l1	PhenoGen
PROSITE	WD_REPEATS_2	UniProtKB/TrEMBL
	WD_REPEATS_REGION	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000023458	RatGTEx
SMART	WD40	UniProtKB/TrEMBL
Superfamily-SCOP	WD40_like	UniProtKB/TrEMBL
UniProt	A6JMN3	ENTREZGENE, UniProtKB/TrEMBL
	D4ABX0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2014-07-21	Dcaf12l1	DDB1 and CUL4 associated factor 12-like 1	Dcaf12	DDB1 and CUL4 associated factor 12	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-08-01	Dcaf12	DDB1 and CUL4 associated factor 12	Dcaf12l1	DDB1 and CUL4 associated factor 12-like 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-05	Dcaf12l1	DDB1 and CUL4 associated factor 12-like 1	Wdr40b	WD repeat domain 40B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-06	Wdr40b	WD repeat domain 40B	RGD1563873_predicted	similar to WD repeat domain 40B (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1563873_predicted	similar to WD repeat domain 40B (predicted)	LOC313296	similar to WD repeat domain 40B	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC313296	similar to WD repeat domain 40B			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar