Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Enox2 | Rat | (-)-epigallocatechin 3-gallate | decreases activity | ISO | ENOX2 (Homo sapiens) | 6480464 | epigallocatechin gallate results in decreased activity of ENOX2 protein | CTD | PMID:20518072 | Enox2 | Rat | (-)-epigallocatechin 3-gallate | increases response to substance | ISO | ENOX2 (Homo sapiens) | 6480464 | ENOX2 results in increased susceptibility to epigallocatechin gallate | CTD | PMID:15706060 | Enox2 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | ENOX2 (Homo sapiens) | 6480464 | [epigallocatechin gallate results in decreased activity of ENOX2 protein] which results in increased abundance of more ... | CTD | PMID:20518072 | Enox2 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Enox2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of ENOX2 mRNA | CTD | PMID:22206623 | Enox2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Enox2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ENOX2 mRNA | CTD | PMID:21570461 | Enox2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ENOX2 mRNA | CTD | PMID:33387578 | Enox2 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | ENOX2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of ENOX2 mRNA | CTD | PMID:30851411 | Enox2 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Enox2 (Mus musculus) | 6480464 | bisphenol S results in increased expression of ENOX2 mRNA | CTD | PMID:31881267 | Enox2 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | ENOX2 (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in decreased methylation of ENOX2 gene | CTD | PMID:31601247 | Enox2 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | ENOX2 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of ENOX2 gene | CTD | PMID:31601247 | Enox2 | Rat | 7,12-dimethyltetraphene | decreases expression | ISO | Enox2 (Mus musculus) | 6480464 | 9,10-Dimethyl-1,2-benzanthracene metabolite results in decreased expression of ENOX2 mRNA | CTD | PMID:32553695 | Enox2 | Rat | aflatoxin B1 | decreases expression | ISO | Enox2 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of ENOX2 mRNA | CTD | PMID:19770486 | Enox2 | Rat | aflatoxin B1 | decreases methylation | ISO | ENOX2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ENOX2 gene | CTD | PMID:27153756 | Enox2 | Rat | aflatoxin B1 | decreases expression | ISO | ENOX2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of ENOX2 mRNA | CTD | PMID:21641981 | Enox2 | Rat | aristolochic acid A | decreases expression | ISO | ENOX2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ENOX2 mRNA | CTD | PMID:33212167 | Enox2 | Rat | arsenous acid | increases expression | ISO | ENOX2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of ENOX2 mRNA | CTD | PMID:20458559 | Enox2 | Rat | asbestos | affects response to substance | ISO | ENOX2 (Homo sapiens) | 6480464 | ENOX2 mRNA alternative form affects the susceptibility to Asbestos | CTD | PMID:26807072 | Enox2 | Rat | benzo[a]pyrene | decreases expression | ISO | ENOX2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ENOX2 mRNA | CTD | PMID:20064835|PMID:20106945|PMID:21632981|PMID:22316170|PMID:26238291 | Enox2 | Rat | benzo[a]pyrene | decreases expression | ISO | Enox2 (Mus musculus) | 6480464 | Benzo(a)pyrene metabolite results in decreased expression of ENOX2 mRNA | CTD | PMID:32553695 | Enox2 | Rat | benzo[a]pyrene | affects methylation | ISO | ENOX2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ENOX2 5' UTR; Benzo(a)pyrene affects the methylation of ENOX2 promoter | CTD | PMID:27901495 | Enox2 | Rat | benzo[a]pyrene diol epoxide I | affects expression | ISO | ENOX2 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of ENOX2 mRNA | CTD | PMID:20382639 | Enox2 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | ENOX2 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ENOX2 mRNA | CTD | PMID:26238291 | Enox2 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in decreased expression of ENOX2 mRNA | CTD | PMID:29945229 | Enox2 | Rat | bisphenol A | decreases expression | ISO | Enox2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of ENOX2 mRNA | CTD | PMID:33221593 | Enox2 | Rat | bisphenol A | decreases methylation | ISO | ENOX2 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of ENOX2 gene | CTD | PMID:31601247 | Enox2 | Rat | bisphenol A | multiple interactions | ISO | ENOX2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ENOX2 gene | CTD | PMID:31601247 | Enox2 | Rat | capsaicin | increases response to substance | ISO | ENOX2 (Homo sapiens) | 6480464 | ENOX2 results in increased susceptibility to Capsaicin | CTD | PMID:15706060 | Enox2 | Rat | carbamazepine | affects expression | ISO | ENOX2 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of ENOX2 mRNA | CTD | PMID:25979313 | Enox2 | Rat | carbon nanotube | decreases expression | ISO | Enox2 (Mus musculus) | 6480464 | Nanotubes, Carbon results in decreased expression of ENOX2 mRNA | CTD | PMID:25554681 | Enox2 | Rat | copper(II) sulfate | decreases expression | ISO | ENOX2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of ENOX2 mRNA | CTD | PMID:19549813 | Enox2 | Rat | diarsenic trioxide | increases expression | ISO | ENOX2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of ENOX2 mRNA | CTD | PMID:20458559 | Enox2 | Rat | doxorubicin | decreases expression | ISO | ENOX2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ENOX2 mRNA | CTD | PMID:29803840 | Enox2 | Rat | endosulfan | increases expression | ISO | ENOX2 (Homo sapiens) | 6480464 | Endosulfan results in increased expression of ENOX2 mRNA | CTD | PMID:26615145 | Enox2 | Rat | folic acid | decreases expression | ISO | Enox2 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of ENOX2 mRNA | CTD | PMID:25629700 | Enox2 | Rat | fulvestrant | multiple interactions | ISO | ENOX2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ENOX2 gene; [bisphenol S co-treated more ... | CTD | PMID:31601247 | Enox2 | Rat | inulin | multiple interactions | ISO | Enox2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ENOX2 mRNA | CTD | PMID:36331819 | Enox2 | Rat | lithium chloride | decreases expression | ISO | ENOX2 (Homo sapiens) | 6480464 | Lithium Chloride results in decreased expression of ENOX2 mRNA | CTD | PMID:23527032 | Enox2 | Rat | methylmercury chloride | decreases expression | ISO | ENOX2 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of ENOX2 mRNA | CTD | PMID:28001369 | Enox2 | Rat | NAD zwitterion | multiple interactions | ISO | ENOX2 (Homo sapiens) | 6480464 | [epigallocatechin gallate results in decreased activity of ENOX2 protein] which results in increased abundance of more ... | CTD | PMID:20518072 | Enox2 | Rat | NAD(+) | multiple interactions | ISO | ENOX2 (Homo sapiens) | 6480464 | [epigallocatechin gallate results in decreased activity of ENOX2 protein] which results in increased abundance of more ... | CTD | PMID:20518072 | Enox2 | Rat | paracetamol | affects expression | ISO | Enox2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of ENOX2 mRNA | CTD | PMID:17562736 | Enox2 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of ENOX2 mRNA | CTD | PMID:33387578 | Enox2 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Enox2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of ENOX2 mRNA | CTD | PMID:36331819 | Enox2 | Rat | pirinixic acid | decreases expression | ISO | Enox2 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of ENOX2 mRNA | CTD | PMID:20813756 | Enox2 | Rat | rac-lactic acid | decreases expression | ISO | ENOX2 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of ENOX2 mRNA | CTD | PMID:30851411 | Enox2 | Rat | sodium arsenite | decreases methylation | ISO | Enox2 (Mus musculus) | 6480464 | sodium arsenite results in decreased methylation of ENOX2 gene | CTD | PMID:39894169 | Enox2 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of ENOX2 mRNA | CTD | PMID:19281266 | Enox2 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of ENOX2 mRNA | CTD | PMID:34492290 | Enox2 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of ENOX2 mRNA | CTD | PMID:33387578 | Enox2 | Rat | triphenyl phosphate | affects expression | ISO | ENOX2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of ENOX2 mRNA | CTD | PMID:37042841 | Enox2 | Rat | triptonide | increases expression | ISO | Enox2 (Mus musculus) | 6480464 | triptonide results in increased expression of ENOX2 mRNA | CTD | PMID:33045310 | Enox2 | Rat | valproic acid | decreases methylation | ISO | ENOX2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of ENOX2 gene | CTD | PMID:29154799 | Enox2 | Rat | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of ENOX2 gene | CTD | PMID:31682807 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















