Cdca4 (cell division cycle associated 4)

Gene: Cdca4 (cell division cycle associated 4) Rattus norvegicus

Analyze

Symbol:

Cdca4

Name:

cell division cycle associated 4

RGD ID:

1563593

Description:

Predicted to be involved in cell division. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in nucleus. Orthologous to human CDCA4 (cell division cycle associated 4); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

cell division cycle-associated protein 4; MGC124732

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	CDCA4 (cell division cycle associated 4)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Cdca4 (cell division cycle associated 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cdca4 (cell division cycle associated 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	CDCA4 (cell division cycle associated 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	CDCA4 (cell division cycle associated 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cdca4 (cell division cycle associated 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	CDCA4 (cell division cycle associated 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	CDCA4 (cell division cycle associated 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cdca4 (cell division cycle associated 4)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	CDCA4 (cell division cycle associated 4)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Cdca4 (cell division cycle associated 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	cdca4 (cell division cycle associated 4)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	cdca4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	137,713,390 - 137,722,652 (-)	NCBI		GRCr8
mRatBN7.2	6	131,892,305 - 131,901,571 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	131,892,087 - 131,901,564 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	132,062,216 - 132,071,505 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	132,352,553 - 132,361,940 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	131,726,809 - 131,736,073 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	137,396,133 - 137,421,283 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	137,396,140 - 137,421,283 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	146,399,231 - 146,423,446 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	137,818,816 - 137,828,119 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	6	129,431,515 - 129,440,777 (-)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Charcot-Marie-Tooth disease axonal type 2O (ISO)

focal segmental glomerulosclerosis 5 (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

acrylamide (EXP,ISO)

aflatoxin B1 (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

cobalt dichloride (EXP,ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

diazinon (EXP,ISO)

dibutyl phthalate (ISO)

dieldrin (EXP)

dioxygen (ISO)

Enterolactone (ISO)

gentamycin (EXP)

indometacin (ISO)

lead(0) (ISO)

leflunomide (ISO)

oxaliplatin (EXP)

paracetamol (EXP,ISO)

piroxicam (ISO)

resveratrol (ISO)

rotenone (ISO)

sodium arsenite (ISO)

Soman (EXP)

sunitinib (ISO)

tamoxifen (ISO)

testosterone (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

topotecan (EXP)

trimellitic anhydride (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell division (IEA)

Cellular Component

cytosol (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IBA,ISO)

plasma membrane (IEA,ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:16546331

Genomics

Comparative Map Data

Cdca4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	137,713,390 - 137,722,652 (-)	NCBI		GRCr8
mRatBN7.2	6	131,892,305 - 131,901,571 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	131,892,087 - 131,901,564 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	132,062,216 - 132,071,505 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	132,352,553 - 132,361,940 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	131,726,809 - 131,736,073 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	137,396,133 - 137,421,283 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	137,396,140 - 137,421,283 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	146,399,231 - 146,423,446 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	137,818,816 - 137,828,119 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	6	129,431,515 - 129,440,777 (-)	NCBI		Celera
Cytogenetic Map	6	q32	NCBI

CDCA4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	105,009,573 - 105,021,083 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	105,009,573 - 105,021,083 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	105,475,910 - 105,487,420 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	104,547,318 - 104,558,538 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	104,547,321 - 104,558,538	NCBI
Celera	14	85,530,125 - 85,541,645 (-)	NCBI		Celera
Cytogenetic Map	14	q32.33	NCBI
HuRef	14	85,669,752 - 85,681,107 (-)	NCBI		HuRef
CHM1_1	14	105,413,682 - 105,425,197 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	99,254,047 - 99,265,639 (-)	NCBI		T2T-CHM13v2.0

Cdca4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	112,783,849 - 112,793,141 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	112,783,849 - 112,793,043 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	112,820,229 - 112,829,521 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	112,820,229 - 112,829,423 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	114,058,445 - 114,067,600 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	113,268,042 - 113,277,197 (-)	NCBI		MGSCv36	mm8
Celera	12	114,028,832 - 114,037,944 (-)	NCBI		Celera
Cytogenetic Map	12	F1	NCBI
cM Map	12	61.2	NCBI

Cdca4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955538	3,344,543 - 3,356,463 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955538	3,345,116 - 3,356,463 (-)	NCBI	ChiLan1.0	ChiLan1.0

CDCA4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	106,195,127 - 106,206,347 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	105,405,385 - 105,422,846 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	85,659,022 - 85,670,182 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	105,443,406 - 105,454,651 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	105,444,672 - 105,445,397 (-)	Ensembl	panpan1.1		panPan2

CDCA4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	72,457,671 - 72,465,630 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	72,458,160 - 72,465,767 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	71,970,004 - 71,978,263 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	72,745,649 - 72,753,914 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	72,745,665 - 72,753,922 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	72,426,346 - 72,434,300 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	72,470,894 - 72,478,845 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	72,866,962 - 72,875,221 (-)	NCBI		UU_Cfam_GSD_1.0

Cdca4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	1,622,967 - 1,629,801 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936621	457,072 - 458,757 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CDCA4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa10.2	7	131,261,595 - 131,274,527 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CDCA4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	82,928,332 - 82,943,701 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	82,929,972 - 82,930,697 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	70,359,928 - 70,371,381 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cdca4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624734	383,667 - 389,554 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624734	375,351 - 390,595 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Cdca4
47 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	65
Count of miRNA genes:	59
Interacting mature miRNAs:	63
Transcripts:	ENSRNOT00000018596
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
724513	Uae14	Urinary albumin excretion QTL 14	6.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	85311061	133478515	Rat
1300076	Glom8	Glomerulus QTL 8	7	0.000000009	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli directly contacting the kidney surface (CMO:0001001)	6	86894788	131894788	Rat
2303624	Vencon5	Ventilatory control QTL 5	4.45		respiration trait (VT:0001943)	minute ventilation (CMO:0000132)	6	88047916	133047916	Rat
61414	Pia3	Pristane induced arthritis QTL 3	4.5		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	6	94968928	137848904	Rat
12801411	Schws8	Schwannoma susceptibility QTL 8			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	94968928	139968928	Rat
8552796	Vie3	Viral induced encephalitis QTL 3	2.6		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	6	96833997	140994061	Rat
1358355	Srcrt4	Stress Responsive Cort QTL 4	6.39		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	100364669	140994061	Rat
2313399	Anxrr28	Anxiety related response QTL 28			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	6	100671796	132340886	Rat
71111	Iddm8	Insulin dependent diabetes mellitus QTL 8	1.9	0.002	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	6	105156861	140994061	Rat
4145118	Mcs26	Mammary carcinoma susceptibility QTL 26		0.0001	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	106752656	132339866	Rat
737976	Pia24	Pristane induced arthritis QTL 24			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	6	112636280	140994061	Rat
1641917	Colcr5	Colorectal carcinoma resistance QTL 5	3.18	0.0009	intestine integrity trait (VT:0010554)	benign colorectal tumor number (CMO:0001795)	6	122549046	137801795	Rat
2293085	Iddm29	Insulin dependent diabetes mellitus QTL 29	7.66		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	6	122549046	140286318	Rat
61329	Eae9	Experimental allergic encephalomyelitis QTL 9	3.7		body mass (VT:0001259)	change in body weight (CMO:0002045)	6	122549046	140994061	Rat
2312560	Pur20	Proteinuria QTL 20	2.1	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	125628133	137801795	Rat

Markers in Region

RH131000

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	131,892,466 - 131,892,657 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	137,396,295 - 137,396,485	NCBI	Rnor6.0
Rnor_5.0	6	146,399,389 - 146,399,579	UniSTS	Rnor5.0
RGSC_v3.4	6	137,818,974 - 137,819,164	UniSTS	RGSC3.4
Celera	6	129,431,673 - 129,431,863	UniSTS
RH 3.4 Map	6	781.61	UniSTS
Cytogenetic Map	6	q32	UniSTS

BI294797

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	131,893,973 - 131,894,146 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	137,397,802 - 137,397,974	NCBI	Rnor6.0
Rnor_5.0	6	146,400,896 - 146,401,068	UniSTS	Rnor5.0
RGSC_v3.4	6	137,820,482 - 137,820,654	UniSTS	RGSC3.4
Celera	6	129,433,180 - 129,433,352	UniSTS
Cytogenetic Map	6	q32	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	28	33	24	19	24			57	21	41	11
Low		15	24	17		17	8	11	17	14			8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001037214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594309	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112763	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001838203	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC107668	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474034	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000018596 ⟹ ENSRNOP00000064942

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	131,892,621 - 131,901,564 (-)	Ensembl
Rnor_6.0 Ensembl	6	137,396,140 - 137,421,283 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000100777 ⟹ ENSRNOP00000088867

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	131,892,087 - 131,901,564 (-)	Ensembl

RefSeq Acc Id:

NM_001037214 ⟹ NP_001032291

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	137,713,390 - 137,722,652 (-)	NCBI
mRatBN7.2	6	131,892,309 - 131,901,571 (-)	NCBI
Rnor_6.0	6	137,396,137 - 137,421,283 (-)	NCBI
Rnor_5.0	6	146,399,231 - 146,423,446 (-)	NCBI
RGSC_v3.4	6	137,818,816 - 137,828,119 (-)	RGD
Celera	6	129,431,515 - 129,440,777 (-)	RGD

Sequence:

show sequence

GGGAACTGGGGGTCGAGCTGTGGACGGACAAGGGATCGGGGGCGGGGCGAGGCGCGGGGAGACA
TGGGAACGGGGGGAGGAGCGGCCCAGCGCGCGAGCCTAACGGCTGAAGTCGAAGCGCGGGAGAC
TCCGCCGGTGAGGCTCCGCCTTGCGTGGGTTTGAACGAAGCTCCGCCCCGCACGCCACCAATCG
GCGCTCGCGCGGCGGCGCCATGGCGACCCTTTGTGGGCACTGACTGATCCCGGGGCCAGACGGA
GTGGCGGGTCTGCCTTGCGGCGCCGGACAGGATGTTTGCTAGAGGCCTGAAGAGGAAATGTGGT
GACCAGGAAGAAGGAGTAGAGGGTTTTGGCACTGTCCCTTCCTATAGCCTGCAGCGACAGTCAC
TCCTGGACATGTCCCTTGTGAAGCTCCAGCTCTGTCACATGCTAGTGGAGCCCAACCTCTGCCG
CTCAGTCCTTATTGCCAACACAGTACGACAGATCCAGGAGGAAATGAGCCAGGATGGCGTGTGG
CATGGGATGGCACCCCAGAGTGTAGAACGGGCACCAATTGACCGACTAGTATCCACAGAGATCC
TGTGTCGTACAGTGAGGGGATCTGAGGGGGAGCACCCCACCTCAGAACTGGAAGACAGTCCCTT
GCAAAGCTCAGCTTCCGAGCTTCCCATCGTTGGCTCAGCACAGGGGCAAAGGAACCCTCAGAGC
AGCCTCTGGGAGATGGACAACCCACAAGAAAACCGGGGAAGCCTTCAGAAGTCCCTGGACCAGA
TATTTGAGACCCTGGAGAACAAAAACTCCAGTTCAGTGGAGGAACTCTTCTCAGATGTGGACAG
CTCCTACTATGACCTGGACACAGTGCTAACAGGAATGATGACTGGGACCAAGTCCAGTCTCTGC
AATGGTCTTGAGAGCTTTACTGCAGCCGCCCCTCCTCCCAGCTCCACTTGCAAGTCTGACCTGG
CTGAACTGGACCACGTCGTAGAGATTCTGGTGGAGACCTGAGAGGACACCCCAGTGGGCCAAGG
ACAAGGCCACCACTCCCCCATGGAGCTCCATGTGCGGTGACCCAGAGACAGACAAGCACTTGTC
CTAAGAGGGGCTCTGACTCTTGAGCCAGGGTCTCCACCTCTGTCTGACTATGAAATATCTGGGA
CAGATTTTCCTCTGCAAGGATCGCAGCCCTGGAGCTGCCTCAGGGCTAGTTAGTTCTTGGGGAG
GACAGAACGGATGCATCTCAAGGAACTGAGCTAGCTCGCTCGCTGAAGGCTCTGGGCTCATTAT
CCTGTGTGTGACACTGGGGTGACTGGAGGATGGTGGGCCACAGCTGTGTCTAGTCTATTTTAAA
TTAGATAGGTGAACTTTCTAAAATTAAGTTTTATATGTTTTGGGCAATATTTTGTCTTAAGATA
TATTTTTTAAACTTTTTATACTTTAGATTTTTTTCAGCTATTTTCTTAAAAGTATATTTTTTCT
ACAAACATCCTCTGCTGCTACATTAGAAACATTTATAACCTAAATACGATTGGTGTGTCATTTT
TAAGGTTTAAATAGAAAACTTTGAGTCTCTACACTTCCAAGGCAACTGTAAATGTAGCCGGCCA
GGTGTTTACATGAGAGGCTCCATTATGGTCTACATTCCAGTAGAGCGCTTGAAGGGAACCATGC
CCAGCCCCACTGCTCCCTCCTCCCTCACTGGGTCTGTCTGTAAGAGCTGTCTTCCCAGGCTTTC
CTGTGCAGGGTGGTTTTATTTATGCCTATTTATATGTAAACGCACTGAGGGCTAAGGTCTTCTG
TCTGGAAATCACAACACCGTTCTTCAGAGACTGTGGTGAGGCAGTGCCTTATGCAGGTCTTGTC
CTTGGGTCCCCAGCCCAGCACTGTGTGACACGAGGACACGACATCCCAACAACAACCAGCACCA
CATGCTACATGTCAAGAGTATGCGTGGAGACTGCAGGGTGCCGGGCATGTGTGTGCTTAGAAAG
GGTGTGCAGCCCACCATGTGCTCAATAGGAGTACCTGTGCTTGCTTGCTTTAAAATGGTGCTTG
AACATTTTAAGGTTAAAAACAATCTGATTCTGTAACTTAGTGCTCCTCCATCCTGGGGTGGCCC
CATGCTGTCTGCTTGGGTCTCATGGTCCCGATAACCAGATCACATGTCAGACCCCACCCCCACC
CCACCATGCTTTTGTTTCTCTTGTGCTGTTCTTTTGGACGTCCCCACCTGAGCCTAAGAGGTTT
TATTTTGTATGTGTTATGACTGTTCTTCACTATCAACAATGTAAACCTCACTTTATTAAAGGAA
TCCAGCAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008764948 ⟹ XP_008763170

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	137,713,390 - 137,722,365 (-)	NCBI
mRatBN7.2	6	131,892,305 - 131,901,284 (-)	NCBI
Rnor_6.0	6	137,396,133 - 137,404,796 (-)	NCBI

Sequence:

show sequence

GGCCGGTGCTGTGCGTGTCCCTTAAGAGCTGCGCGTGGCCAGCAGTTTTGGGGGGACTGGACTT
TGTCTGGCTTCTAGCCCCGAGCGTCTGTCTGCTAGCCAGAGACCGATTCCGAGAGGGCTGGGTG
GACTCCGTGCAGTCGCCTGCCTGGACAGGATGTTTGCTAGAGGCCTGAAGAGGAAATGTGGTGA
CCAGGAAGAAGGAGTAGAGGGTTTTGGCACTGTCCCTTCCTATAGCCTGCAGCGACAGTCACTC
CTGGACATGTCCCTTGTGAAGCTCCAGCTCTGTCACATGCTAGTGGAGCCCAACCTCTGCCGCT
CAGTCCTTATTGCCAACACAGTACGACAGATCCAGGAGGAAATGAGCCAGGATGGCGTGTGGCA
TGGGATGGCACCCCAGAGTGTAGAACGGGCACCAATTGACCGACTAGTATCCACAGAGATCCTG
TGTCGTACAGTGAGGGGATCTGAGGGGGAGCACCCCACCTCAGAACTGGAAGACAGTCCCTTGC
AAAGCTCAGCTTCCGAGCTTCCCATCGTTGGCTCAGCACAGGGGCAAAGGAACCCTCAGAGCAG
CCTCTGGGAGATGGACAACCCACAAGAAAACCGGGGAAGCCTTCAGAAGTCCCTGGACCAGATA
TTTGAGACCCTGGAGAACAAAAACTCCAGTTCAGTGGAGGAACTCTTCTCAGATGTGGACAGCT
CCTACTATGACCTGGACACAGTGCTAACAGGAATGATGACTGGGACCAAGTCCAGTCTCTGCAA
TGGTCTTGAGAGCTTTACTGCAGCCGCCCCTCCTCCCAGCTCCACTTGCAAGTCTGACCTGGCT
GAACTGGACCACGTCGTAGAGATTCTGGTGGAGACCTGAGAGGACACCCCAGTGGGCCAAGGAC
AAGGCCACCACTCCCCCATGGAGCTCCATGTGCGGTGACCCAGAGACAGACAAGCACTTGTCCT
AAGAGGGGCTCTGACTCTTGAGCCAGGGTCTCCACCTCTGTCTGACTATGAAATATCTGGGACA
GATTTTCCTCTGCAAGGATCGCAGCCCTGGAGCTGCCTCAGGGCTAGTTAGTTCTTGGGGAGGA
CAGAACGGATGCATCTCAAGGAACTGAGCTAGCTCGCTCGCTGAAGGCTCTGGGCTCATTATCC
TGTGTGTGACACTGGGGTGACTGGAGGATGGTGGGCCACAGCTGTGTCTAGTCTATTTTAAATT
AGATAGGTGAACTTTCTAAAATTAAGTTTTATATGTTTTGGGCAATATTTTGTCTTAAGATATA
TTTTTTAAACTTTTTATACTTTAGATTTTTTTCAGCTATTTTCTTAAAAGTATATTTTTTCTAC
AAACATCCTCTGCTGCTACATTAGAAACATTTATAACCTAAATACGATTGGTGTGTCATTTTTA
AGGTTTAAATAGAAAACTTTGAGTCTCTACACTTCCAAGGCAACTGTAAATGTAGCCGGCCAGG
TGTTTACATGAGAGGCTCCATTATGGTCTACATTCCAGTAGAGCGCTTGAAGGGAACCATGCCC
AGCCCCACTGCTCCCTCCTCCCTCACTGGGTCTGTCTGTAAGAGCTGTCTTCCCAGGCTTTCCT
GTGCAGGGTGGTTTTATTTATGCCTATTTATATGTAAACGCACTGAGGGCTAAGGTCTTCTGTC
TGGAAATCACAACACCGTTCTTCAGAGACTGTGGTGAGGCAGTGCCTTATGCAGGTCTTGTCCT
TGGGTCCCCAGCCCAGCACTGTGTGACACGAGGACACGACATCCCAACAACAACCAGCACCACA
TGCTACATGTCAAGAGTATGCGTGGAGACTGCAGGGTGCCGGGCATGTGTGTGCTTAGAAAGGG
TGTGCAGCCCACCATGTGCTCAATAGGAGTACCTGTGCTTGCTTGCTTTAAAATGGTGCTTGAA
CATTTTAAGGTTAAAAACAATCTGATTCTGTAACTTAGTGCTCCTCCATCCTGGGGTGGCCCCA
TGCTGTCTGCTTGGGTCTCATGGTCCCGATAACCAGATCACATGTCAGACCCCACCCCCACCCC
ACCATGCTTTTGTTTCTCTTGTGCTGTTCTTTTGGACGTCCCCACCTGAGCCTAAGAGGTTTTA
TTTTGTATGTGTTATGACTGTTCTTCACTATCAACAATGTAAACCTCACTTTATTAAAGGAATC
CAGCAAATGGA

hide sequence

RefSeq Acc Id:

XM_039112763 ⟹ XP_038968691

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	137,713,390 - 137,722,600 (-)	NCBI
mRatBN7.2	6	131,892,305 - 131,901,284 (-)	NCBI

RefSeq Acc Id:

XM_039112764 ⟹ XP_038968692

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	137,713,390 - 137,722,600 (-)	NCBI
mRatBN7.2	6	131,892,305 - 131,901,483 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001032291	(Get FASTA)	NCBI Sequence Viewer
	XP_008763170	(Get FASTA)	NCBI Sequence Viewer
	XP_038968691	(Get FASTA)	NCBI Sequence Viewer
	XP_038968692	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI07669	(Get FASTA)	NCBI Sequence Viewer
	EDL97414	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000064942
	ENSRNOP00000064942.2
	ENSRNOP00000088867
	ENSRNOP00000088867.1

RefSeq Acc Id:

NP_001032291 ⟸ NM_001037214

- UniProtKB:

Q3B7C7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MFARGLKRKCGDQEEGVEGFGTVPSYSLQRQSLLDMSLVKLQLCHMLVEPNLCRSVLIANTVRQ
IQEEMSQDGVWHGMAPQSVERAPIDRLVSTEILCRTVRGSEGEHPTSELEDSPLQSSASELPIV
GSAQGQRNPQSSLWEMDNPQENRGSLQKSLDQIFETLENKNSSSVEELFSDVDSSYYDLDTVLT
GMMTGTKSSLCNGLESFTAAAPPPSSTCKSDLAELDHVVEILVET

hide sequence

RefSeq Acc Id:	XP_008763170 ⟸ XM_008764948
- Peptide Label:	isoform X2
- UniProtKB:	Q3B7C7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MFARGLKRKCGDQEEGVEGFGTVPSYSLQRQSLLDMSLVKLQLCHMLVEPNLCRSVLIANTVRQ IQEEMSQDGVWHGMAPQSVERAPIDRLVSTEILCRTVRGSEGEHPTSELEDSPLQSSASELPIV GSAQGQRNPQSSLWEMDNPQENRGSLQKSLDQIFETLENKNSSSVEELFSDVDSSYYDLDTVLT GMMTGTKSSLCNGLESFTAAAPPPSSTCKSDLAELDHVVEILVET hide sequence

RefSeq Acc Id:

ENSRNOP00000064942 ⟸ ENSRNOT00000018596

RefSeq Acc Id:	XP_038968692 ⟸ XM_039112764
- Peptide Label:	isoform X1
- UniProtKB:	M0R698 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968691 ⟸ XM_039112763
- Peptide Label:	isoform X1
- UniProtKB:	M0R698 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000088867 ⟸ ENSRNOT00000100777

Protein Domains

SERTA

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q3B7C7-F1-model_v2	AlphaFold	Q3B7C7	1-237	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694856

Promoter ID:

EPDNEW_R5379

Type:

multiple initiation site

Name:

Cdca4_1

Description:

cell division cycle associated 4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	137,421,100 - 137,421,160	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563593	AgrOrtholog
BioCyc Gene	G2FUF-35773	BioCyc
Ensembl Genes	ENSRNOG00000013898	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000018596.6	UniProtKB/TrEMBL
	ENSRNOT00000100777.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7937865	IMAGE-MGC_LOAD
InterPro	SERTA	UniProtKB/TrEMBL
KEGG Report	rno:500727	UniProtKB/TrEMBL
MGC_CLONE	MGC:124732	IMAGE-MGC_LOAD
NCBI Gene	500727	ENTREZGENE
PANTHER	CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2	UniProtKB/TrEMBL
	CELL DIVISION CYCLE-ASSOCIATED PROTEIN 4	UniProtKB/TrEMBL
Pfam	SERTA	UniProtKB/TrEMBL
PhenoGen	Cdca4	PhenoGen
PROSITE	SERTA	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000013898	RatGTEx
UniProt	A6KBW7_RAT	UniProtKB/TrEMBL
	M0R698	ENTREZGENE, UniProtKB/TrEMBL
	Q3B7C7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-02-09	Cdca4	cell division cycle associated 4			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar