Rps23l1 (ribosomal protein S23 like 1) - Rat Genome Database

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Gene: Rps23l1 (ribosomal protein S23 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Rps23l1
Name: ribosomal protein S23 like 1
RGD ID: 1563570
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytosolic ribosome and rough endoplasmic reticulum. Predicted to be part of cytosolic small ribosomal subunit. Predicted to be active in ribosome. Human ortholog(s) of this gene implicated in brachycephaly, trichomegaly, and developmental delay. Orthologous to human RPS23 (ribosomal protein S23); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; rotenone.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 40S ribosomal protein S23-like; LOC498360; RGD1563570; similar to ribosomal protein S23; small ribosomal subunit protein uS12-like
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81442,399,498 - 42,400,015 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1442,399,497 - 42,400,034 (+)EnsemblGRCr8
mRatBN7.21442,045,749 - 42,046,255 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1442,045,775 - 42,046,206 (+)EnsemblmRatBN7.2
Rnor_6.01443,685,899 - 43,694,618 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01443,483,176 - 43,483,611 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41444,696,678 - 44,697,109 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1441,189,902 - 41,198,645 (+)NCBICelera
Cytogenetic Map14p11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
translation  (IBA,IEA)

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:30
Interacting mature miRNAs:33
Transcripts:ENSRNOT00000046342
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313089Bss81Bone structure and strength QTL 813.40.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)143802371083023710Rat
70214Niddm28Non-insulin dependent diabetes mellitus QTL 284.06blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)143900944484009444Rat
1300154Bp189Blood pressure QTL 1893.04arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)143123808072970315Rat
70187Pancm5Pancreatic morphology QTL 516.7pancreas mass (VT:0010144)pancreas weight to body weight ratio (CMO:0000630)143067446985041098Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14862139853621398Rat
61420Pia6Pristane induced arthritis QTL 64.9joint integrity trait (VT:0010548)arthritic paw count (CMO:0001460)141891545442433608Rat
2313100Bss82Bone structure and strength QTL 8230.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143802371083023710Rat
7387267Uae42Urinary albumin excretion QTL 420.61urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)142252151767521517Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
2313397Coatc1Coat color QTL1coat/hair pigmentation trait (VT:0010463)coat/hair color measurement (CMO:0001808)141889519263895192Rat
631262Tcas4Tongue tumor susceptibility QTL 47.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)141790672654251504Rat
2313048Bss84Bone structure and strength QTL 843.10.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143802371083023710Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14862139853621398Rat
738037Hcas6Hepatocarcinoma susceptibility QTL 62.93liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)143941117087582095Rat
2313084Bss83Bone structure and strength QTL 832.90.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143802371083023710Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
13 1 24 77 31 27 15 73 15 6 193 119 11 64 46 48 12 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000046342   ⟹   ENSRNOP00000040548
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1442,045,775 - 42,046,206 (+)Ensembl
Rnor_6.0 Ensembl1443,694,183 - 43,694,611 (+)Ensembl
RefSeq Acc Id: XM_039092587   ⟹   XP_038948515
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81442,399,498 - 42,400,015 (+)NCBI
mRatBN7.21442,045,749 - 42,046,255 (+)NCBI
Protein Sequences
Protein RefSeqs XP_038948515 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000040548
  ENSRNOP00000040548.3
RefSeq Acc Id: XP_038948515   ⟸   XM_039092587
- UniProtKB: D4A9Q3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000040548   ⟸   ENSRNOT00000046342

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A9Q3-F1-model_v2 AlphaFold D4A9Q3 1-143 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563570 AgrOrtholog
BioCyc Gene G2FUF-15761 BioCyc
Ensembl Genes ENSRNOG00000029461 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000046342 ENTREZGENE
  ENSRNOT00000046342.7 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.140 UniProtKB/TrEMBL
InterPro NA-bd_OB-fold UniProtKB/TrEMBL
  Ribosomal_S12/S23 UniProtKB/TrEMBL
  Ribosomal_S23_euk/arc UniProtKB/TrEMBL
NCBI Gene 498360 ENTREZGENE
PANTHER PTHR11652 UniProtKB/TrEMBL
Pfam Ribosom_S12_S23 UniProtKB/TrEMBL
PhenoGen Rps23l1 PhenoGen
PIRSF Ribosomal_S12/S23 UniProtKB/TrEMBL
PROSITE RIBOSOMAL_S12 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000029461 RatGTEx
Superfamily-SCOP SSF50249 UniProtKB/TrEMBL
UniProt D4A9Q3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Rps23l1  ribosomal protein S23 like 1  RGD1563570  similar to ribosomal protein S23  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1563570  similar to ribosomal protein S23   RGD1563570_predicted  similar to ribosomal protein S23 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1563570_predicted  similar to ribosomal protein S23 (predicted)  LOC498360  similar to ribosomal protein S23  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498360  similar to ribosomal protein S23      Symbol and Name status set to provisional 70820 PROVISIONAL