Stk26 (serine/threonine kinase 26)

Gene: Stk26 (serine/threonine kinase 26) Rattus norvegicus

Analyze

Symbol:

Stk26

Name:

serine/threonine kinase 26

RGD ID:

1563568

Description:

Predicted to enable ion binding activity; protein homodimerization activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including microvillus assembly; response to hydrogen peroxide; and stress-activated protein kinase signaling cascade. Located in Golgi membrane. Orthologous to human STK26 (serine/threonine kinase 26); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC317589; Mask; Mst4; RGD1563568; serine/threonine protein kinase 26; serine/threonine protein kinase MST4; serine/threonine-protein kinase 26; serine/threonine-protein kinase MST4; similar to serine/threonine protein kinase MST4a

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	STK26 (serine/threonine kinase 26)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Treefam
Mus musculus (house mouse):	Stk26 (serine/threonine kinase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Stk26 (serine/threonine kinase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	STK26 (serine/threonine kinase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	STK26 (serine/threonine kinase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Stk26 (serine/threonine kinase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	STK26 (serine/threonine kinase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	STK26 (serine/threonine kinase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Stk26 (serine/threonine kinase 26)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	STK24 (serine/threonine kinase 24)	HGNC	OrthoDB
Homo sapiens (human):	PDXK (pyridoxal kinase)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Stk26 (serine/threonine kinase 26)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	STK26 (serine/threonine kinase 26)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	stk26 (serine/threonine protein kinase 26)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	KIC1	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SPS1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	gck-1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	GckIII	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	stk26	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	135,195,176 - 135,259,994 (+)	NCBI		GRCr8
mRatBN7.2	X	130,325,064 - 130,375,674 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	130,310,885 - 130,374,291 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	132,445,297 - 132,495,904 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	136,027,191 - 136,077,794 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	133,590,437 - 133,641,092 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	138,032,356 - 138,096,632 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	138,046,494 - 138,096,669 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	138,091,166 - 138,155,429 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	137,577,961 - 137,627,511 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	129,243,275 - 129,292,475 (+)	NCBI		Celera
Cytogenetic Map	X	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

genetic disease (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acrylamide (EXP)

afimoxifene (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium atom (ISO)

cadmium sulfate (ISO)

calcitriol (ISO)

cannabidiol (ISO)

carbamazepine (ISO)

chlordecone (ISO)

chlormequat chloride (EXP)

chromium atom (ISO)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

Cuprizon (ISO)

cyclosporin A (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

FR900359 (ISO)

fulvestrant (ISO)

gentamycin (EXP)

glycidyl methacrylate (ISO)

gold atom (ISO)

gold(0) (ISO)

isobutanol (ISO)

ivermectin (ISO)

lead(II) chloride (ISO)

lipopolysaccharide (ISO)

methylmercury chloride (ISO)

monosodium L-glutamate (ISO)

paracetamol (EXP,ISO)

quercetin (ISO)

raloxifene (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

sodium tungstate (ISO)

succimer (ISO)

sunitinib (ISO)

trichloroethene (EXP)

triclosan (ISO)

tris(2-butoxyethyl) phosphate (ISO)

valproic acid (ISO)

vincaleukoblastine (ISO)

vinclozolin (EXP)

vorinostat (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to oxidative stress (IEA,ISO)

cellular response to starvation (ISO)

intracellular signal transduction (ISO)

microvillus assembly (ISO)

negative regulation of cell migration (IBA,ISO)

regulation of apoptotic process (ISO)

Cellular Component

apical plasma membrane (ISO)

cell periphery (ISO)

cytoplasm (IBA,ISO)

cytosol (ISO)

FAR/SIN/STRIPAK complex (ISO)

Golgi apparatus (IBA,ISO)

Golgi membrane (IDA)

Golgi-associated vesicle (ISO)

membrane (ISO)

perinuclear region of cytoplasm (ISO)

Molecular Function

ATP binding (ISO)

identical protein binding (ISO)

magnesium ion binding (ISO)

protein binding (ISO)

protein homodimerization activity (ISO)

protein kinase activity (ISO)

protein serine/threonine kinase activity (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	CCM3/PDCD10 stabilizes GCKIII proteins to promote Golgi assembly and cell orientation.	Fidalgo M, etal., J Cell Sci. 2010 Apr 15;123(Pt 8):1274-84. doi: 10.1242/jcs.061341. Epub 2010 Mar 23.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11641781	PMID:11741893	PMID:15037601	PMID:17360971	PMID:21561863	PMID:22291017	PMID:22797597	PMID:23533145	PMID:27807006

Genomics

Comparative Map Data

Stk26
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	135,195,176 - 135,259,994 (+)	NCBI		GRCr8
mRatBN7.2	X	130,325,064 - 130,375,674 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	130,310,885 - 130,374,291 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	132,445,297 - 132,495,904 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	136,027,191 - 136,077,794 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	133,590,437 - 133,641,092 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	138,032,356 - 138,096,632 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	138,046,494 - 138,096,669 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	X	138,091,166 - 138,155,429 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	137,577,961 - 137,627,511 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	X	129,243,275 - 129,292,475 (+)	NCBI		Celera
Cytogenetic Map	X	q36	NCBI

STK26
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	132,023,302 - 132,075,943 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	132,023,302 - 132,075,943 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	131,157,330 - 131,209,971 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	130,984,926 - 131,037,652 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	X	131,543,656 - 131,596,380 (+)	NCBI		Celera
Cytogenetic Map	X	q26.2	NCBI
HuRef	X	120,561,932 - 120,614,415 (+)	NCBI		HuRef
CHM1_1	X	131,068,821 - 131,121,548 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	130,347,539 - 130,400,176 (+)	NCBI		T2T-CHM13v2.0

Stk26
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	49,930,052 - 49,981,980 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	49,929,924 - 49,981,974 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	50,841,174 - 50,893,103 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	50,841,047 - 50,893,097 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	48,194,613 - 48,245,033 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	47,086,063 - 47,136,483 (+)	NCBI		MGSCv36	mm8
Celera	X	38,259,039 - 38,309,780 (+)	NCBI		Celera
Cytogenetic Map	X	A5	NCBI
cM Map	X	27.5	NCBI

Stk26
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955473	2,819,585 - 2,878,561 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955473	2,819,644 - 2,878,561 (-)	NCBI	ChiLan1.0	ChiLan1.0

STK26
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	131,449,104 - 131,501,584 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	131,452,713 - 131,505,193 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	121,155,443 - 121,207,906 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	131,462,895 - 131,515,429 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	131,463,187 - 131,515,429 (+)	Ensembl	panpan1.1		panPan2

STK26
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	102,962,012 - 103,026,278 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	102,961,648 - 103,024,503 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	89,134,974 - 89,199,270 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	104,849,346 - 104,886,322 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	104,836,856 - 104,886,320 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	102,232,961 - 102,297,253 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	104,109,765 - 104,173,599 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	103,880,672 - 103,944,681 (+)	NCBI		UU_Cfam_GSD_1.0

Stk26
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	101,130,295 - 101,199,432 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936691	2,757,934 - 2,811,937 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936691	2,757,934 - 2,811,961 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

STK26
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	108,178,698 - 108,239,042 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	108,179,230 - 108,237,669 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	124,210,635 - 124,230,967 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

STK26
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	107,179,800 - 107,233,336 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	107,181,020 - 107,233,332 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	44,641,530 - 44,693,955 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Stk26
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624797	11,714,508 - 11,768,800 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624797	11,714,548 - 11,768,712 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Stk26
140 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	68
Count of miRNA genes:	58
Interacting mature miRNAs:	66
Transcripts:	ENSRNOT00000010596
Prediction methods:	Miranda, Pita, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1598837	Memor13	Memory QTL 13	3.2		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	41052407	146860749	Rat
1598872	Memor14	Memory QTL 14	4.5		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	93956491	138956491	Rat
738025	Stresp3	Stress response QTL 3	4.61	0.0066	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	100567703	150256146	Rat
1598809	Memor15	Memory QTL 15	4.4		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	X	103312877	148312877	Rat
1598856	Memor1	Memory QTL 1	1.9		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	X	103312877	148312877	Rat
738029	Stresp2	Stress response QTL 2	3.4	0.0004	stress-related behavior trait (VT:0010451)	defensive burying - approach	X	112934952	138400867	Rat
10059603	Bw174	Body weight QTL 174	3.4	0.025	body mass (VT:0001259)	body weight (CMO:0000012)	X	113937816	152453651	Rat
634346	Insul4	Insulin level QTL 4	0		blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	X	126975089	152453651	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	12	14	6	19	6			2	18	31	4
Low	1	29	36	28		28	8	8	72	17	10	7	8
Below cutoff		2	7	7		7		3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191736	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063280092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063280093	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473991	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000010596 ⟹ ENSRNOP00000010596

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	130,325,066 - 130,374,291 (+)	Ensembl
Rnor_6.0 Ensembl	X	138,046,494 - 138,096,669 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099912 ⟹ ENSRNOP00000084325

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	130,310,885 - 130,374,291 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000104737 ⟹ ENSRNOP00000082800

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	X	130,352,955 - 130,372,258 (+)	Ensembl

RefSeq Acc Id:

NM_001191736 ⟹ NP_001178665

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	135,209,386 - 135,259,994 (+)	NCBI
mRatBN7.2	X	130,325,064 - 130,375,674 (+)	NCBI
Rnor_6.0	X	138,046,539 - 138,095,249 (+)	NCBI
Rnor_5.0	X	138,091,166 - 138,155,429 (+)	NCBI
Celera	X	129,243,275 - 129,292,475 (+)	NCBI

Sequence:

show sequence

CACTGGAGCCCAGGTCCCAGCCACTGCCGCACGCACAGCTCTGCATTCAGGAAGAGGAGCGGCA
CCGCAACTGTCCGAAAGCTAGGCGGGCGAGCGTCAGAGAGGCCCCGATCGAGAAGCCTGGGAGA
GCTGCAGAGCTACCCCCGTAGGAGGAGCCAGTCTGTGCCCCAGGAGCCACCACCGCAGAAGCAG
CGCGAAGTAGCAGCCGCCTCCATGGCCCACTCACCGGTGGCTGTTCAAGTGCCCGGGATGCAGA
ATAATATCGCGGATCCAGAAGAACTGTTCACAAAATTAGAGCGCATTGGAAAAGGCTCCTTTGG
AGAAGTTTTCAAAGGAATCGATAACCGAACTCAGCAAGTGGTTGCAATTAAAATCATTGACCTT
GAGGAAGCCGAGGATGAAATAGAAGACATCCAACAAGAGATAACTGTTTTGAGTCAGTGCGACA
GCTCATATGTTACAAAATACTATGGGTCCTATCTAAAGGGTTCAAAACTATGGATAATAATGGA
ATACCTAGGTGGTGGTTCAGCATTGGATCTTCTACGGGCCGGTCCATTTGATGAATTCCAGATT
GCCACCATGCTCAAGGAGATTTTGAAAGGTCTGGACTATCTACATTCTGAAAAGAAAATTCACC
GAGACATTAAAGCTGCCAACGTCTTGCTTTCAGAACAAGGTGATGTTAAACTGGCTGACTTCGG
AGTTGCTGGCCAGCTGACAGACACACAAATTAAAAGAAACACCTTTGTAGGAACTCCATTTTGG
ATGGCTCCTGAAGTTATTCAACAGTCAGCTTATGACTCTAAAGCTGACATATGGTCTTTGGGAA
TTACTGCTATTGAACTTGCCAAGGGAGAGCCTCCGAATTCTGACATGCATCCAATGAGAGTTCT
GTTTCTTATTCCAAAAAACAACCCCCCAACGCTTGTTGGAGACTTTACTAAGTCTTTCAAGGAG
TTTATTGATGCTTGCCTGAATAAAGACCCATCATTTCGTCCTACGGCTAAAGAACTTTTGAAGC
ATAAGTTCATCGTAAAAAATTCAAAGAAGACTTCTTATCTGACTGAGTTGATTGATCGATTTAA
GAGATGGAAGGCAGAAGGCCACAGTGATGAGGAATCCGATTCTGAGGGCTCTGACTCGGAATCC
AGCAGCAGGGAAAGTAATACCCACCCTGAATGGAGTTTCACCACTGTGCGTAAGAAGCCTGATC
CAAAGAAACTGCAGAATGGGGAAGAGCAAGATCTTGTGCAAACCCTGAGCTGTTTGTCTATGAT
AATCACACCTGCATTTGCTGAACTTAAACAGCAGGATGAGAACAATGCAAGCCGAAACCAGGCA
ATTGAAGAACTTGAGAAAAGTATTGCTGTGGCCGAAGCTGCCTGTCCTGGCATCACAGATAAAA
TGGTGAAGAAACTAATCGAAAAATTTCAAAAGTGTTCTGCGGATGAATCCCCTTAAGAAATTTG
TTGTCATTCTTTTGGCTTCTGTTTCATGTGGACCAGGAGAAACCCACCAAAGCTATGTCAACCT
TAATAATGCTTAACTCATGAGCTCCATGTGCCTTTTGGATCTTTGCCACATTGAAGATTTAGAG
GAAGCTATTCAACTATTTTGTGATGGTGGCTATCATTTTGTATTTTAAAGAGATTATTTTGTAT
GGAATAATTTTAATACTATAGTTTTGCCTGTATTGTAGTAAATGTTGAGATACAGTGTTTTTGT
TTTTTGATTTTTTTTGTTTTTTTTTTGTTTTTTTATTTTAGGTACCGTTATTTCTTATGTTCTT
GGAACGAATACTGTTTGGTATGGAATTTAGTTAACTGTACACTCATAAACATACAGGTCTTTCA
ACGTCATCCTAATTATTAAATGTTTG

hide sequence

RefSeq Acc Id:

XM_063280092 ⟹ XP_063136162

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	135,195,176 - 135,259,994 (+)	NCBI

RefSeq Acc Id:

XM_063280093 ⟹ XP_063136163

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	X	135,195,176 - 135,259,994 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001178665	(Get FASTA)	NCBI Sequence Viewer
	XP_063136162	(Get FASTA)	NCBI Sequence Viewer
	XP_063136163	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM10941	(Get FASTA)	NCBI Sequence Viewer
	EDM10942	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000010596
	ENSRNOP00000010596.7
	ENSRNOP00000082800.1
	ENSRNOP00000084325.1

RefSeq Acc Id:

NP_001178665 ⟸ NM_001191736

- UniProtKB:

A6JMS9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAHSPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEAEDEI
EDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLRAGPFDEFQIATMLKEI
LKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQ
QSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLN
KDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDRFKRWKAEGHSDEESDSEGSDSESSSRESNT
HPEWSFTTVRKKPDPKKLQNGEEQDLVQTLSCLSMIITPAFAELKQQDENNASRNQAIEELEKS
IAVAEAACPGITDKMVKKLIEKFQKCSADESP

hide sequence

RefSeq Acc Id:

ENSRNOP00000010596 ⟸ ENSRNOT00000010596

RefSeq Acc Id:

ENSRNOP00000082800 ⟸ ENSRNOT00000104737

RefSeq Acc Id:

ENSRNOP00000084325 ⟸ ENSRNOT00000099912

RefSeq Acc Id:	XP_063136162 ⟸ XM_063280092
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063136163 ⟸ XM_063280093
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6GBQ0 (UniProtKB/TrEMBL)

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1LXV3-F1-model_v2	AlphaFold	F1LXV3	1-416	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13702017

Promoter ID:

EPDNEW_R12541

Type:

initiation region

Name:

Stk26_1

Description:

serine/threonine kinase 26

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	X	138,046,540 - 138,046,600	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563568	AgrOrtholog
BioCyc Gene	G2FUF-1053	BioCyc
Ensembl Genes	ENSRNOG00000007879	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000010596	ENTREZGENE
	ENSRNOT00000010596.8	UniProtKB/TrEMBL
	ENSRNOT00000099912.1	UniProtKB/TrEMBL
	ENSRNOT00000104737.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.12.70	UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	Kinase-like_dom	UniProtKB/TrEMBL
	PDC10_dimerisation_sf	UniProtKB/TrEMBL
	PDCD10_N	UniProtKB/TrEMBL
	Prot_kinase_cat_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	Ser-Thr/Tyr_kinase_cat_dom	UniProtKB/TrEMBL
	STK_MST4	UniProtKB/TrEMBL
NCBI Gene	317589	ENTREZGENE
PANTHER	SERINE/THREONINE-PROTEIN KINASE 26	UniProtKB/TrEMBL
	STERILE20-LIKE KINASE, ISOFORM B-RELATED	UniProtKB/TrEMBL
Pfam	PDCD10_N	UniProtKB/TrEMBL
	Pkinase	UniProtKB/TrEMBL
PhenoGen	Stk26	PhenoGen
PRINTS	TYRKINASE	UniProtKB/TrEMBL
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000007879	RatGTEx
SMART	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	Kinase_like	UniProtKB/TrEMBL
UniProt	A0A8I5ZV99_RAT	UniProtKB/TrEMBL
	A0A8I6GBQ0	ENTREZGENE, UniProtKB/TrEMBL
	A6JMS9	ENTREZGENE, UniProtKB/TrEMBL
	F1LXV3_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-01-03	Stk26	serine/threonine kinase 26	Stk26	serine/threonine protein kinase 26	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-09-24	Stk26	serine/threonine protein kinase 26	Mst4	serine/threonine protein kinase MST4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-02-04	Mst4	serine/threonine protein kinase MST4	Mask	serine/threonine protein kinase MST4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-01-14	Mask	serine/threonine protein kinase MST4	Mst4	serine/threonine protein kinase MST4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-07	Mst4	serine/threonine protein kinase MST4	RGD1563568_predicted	similar to serine/threonine protein kinase MST4a (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1563568_predicted	similar to serine/threonine protein kinase MST4a (predicted)	LOC317589	similar to serine/threonine protein kinase MST4a	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC317589	similar to serine/threonine protein kinase MST4a			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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