Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Shroom4 | Rat | 17beta-estradiol | multiple interactions | ISO | SHROOM4 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of SHROOM4 mRNA | CTD | PMID:30165855 | Shroom4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SHROOM4 mRNA | CTD | PMID:34747641 | Shroom4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SHROOM4 mRNA | CTD | PMID:33387578 | Shroom4 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of SHROOM4 mRNA | CTD | PMID:32109520 | Shroom4 | Rat | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of SHROOM4 mRNA | CTD | PMID:32119087 | Shroom4 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Shroom4 (Mus musculus) | 6480464 | bisphenol S results in increased expression of SHROOM4 mRNA | CTD | PMID:30951980 | Shroom4 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Shroom4 (Mus musculus) | 6480464 | Fenretinide results in increased expression of SHROOM4 mRNA | CTD | PMID:28973697 | Shroom4 | Rat | antirheumatic drug | increases expression | ISO | SHROOM4 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of SHROOM4 mRNA | CTD | PMID:24449571 | Shroom4 | Rat | aristolochic acid A | decreases expression | ISO | SHROOM4 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SHROOM4 mRNA | CTD | PMID:33212167 | Shroom4 | Rat | benzo[a]pyrene | affects methylation | ISO | SHROOM4 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SHROOM4 exon | CTD | PMID:27901495 | Shroom4 | Rat | benzo[a]pyrene | decreases methylation | ISO | SHROOM4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of SHROOM4 3' UTR | CTD | PMID:27901495 | Shroom4 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SHROOM4 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:32528016|PMID:34947998 | Shroom4 | Rat | bisphenol A | multiple interactions | ISO | SHROOM4 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of SHROOM4 gene | CTD | PMID:31601247 | Shroom4 | Rat | bisphenol F | increases expression | ISO | Shroom4 (Mus musculus) | 6480464 | bisphenol F results in increased expression of SHROOM4 mRNA | CTD | PMID:30951980 | Shroom4 | Rat | cadmium atom | multiple interactions | ISO | Shroom4 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SHROOM4 more ... | CTD | PMID:37236586 | Shroom4 | Rat | cadmium dichloride | multiple interactions | ISO | Shroom4 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SHROOM4 more ... | CTD | PMID:37236586 | Shroom4 | Rat | cefaloridine | decreases expression | EXP | | 6480464 | Cephaloridine results in decreased expression of SHROOM4 mRNA | CTD | PMID:18500788 | Shroom4 | Rat | choline | multiple interactions | ISO | Shroom4 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... | CTD | PMID:20938992 | Shroom4 | Rat | dibutyl phthalate | increases expression | ISO | Shroom4 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of SHROOM4 mRNA | CTD | PMID:21266533 | Shroom4 | Rat | dimethylarsinic acid | multiple interactions | ISO | Shroom4 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Shroom4 | Rat | doxorubicin | decreases expression | ISO | SHROOM4 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SHROOM4 mRNA | CTD | PMID:29803840 | Shroom4 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of SHROOM4 mRNA | CTD | PMID:29391264 | Shroom4 | Rat | folic acid | multiple interactions | ISO | Shroom4 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... | CTD | PMID:20938992 | Shroom4 | Rat | FR900359 | affects phosphorylation | ISO | SHROOM4 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of SHROOM4 protein | CTD | PMID:37730182 | Shroom4 | Rat | fulvestrant | multiple interactions | ISO | SHROOM4 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of SHROOM4 gene | CTD | PMID:31601247 | Shroom4 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SHROOM4 mRNA | CTD | PMID:33387578 | Shroom4 | Rat | L-methionine | multiple interactions | ISO | Shroom4 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation more ... | CTD | PMID:20938992 | Shroom4 | Rat | methotrexate | increases mutagenesis | ISO | Shroom4 (Mus musculus) | 6480464 | Methotrexate results in increased mutagenesis of SHROOM4 gene | CTD | PMID:22806879 | Shroom4 | Rat | methylarsonic acid | multiple interactions | ISO | Shroom4 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Shroom4 | Rat | nickel atom | decreases expression | ISO | SHROOM4 (Homo sapiens) | 6480464 | Nickel results in decreased expression of SHROOM4 mRNA | CTD | PMID:25583101 | Shroom4 | Rat | paracetamol | affects expression | ISO | Shroom4 (Mus musculus) | 6480464 | Acetaminophen affects the expression of SHROOM4 mRNA | CTD | PMID:17562736 | Shroom4 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SHROOM4 mRNA | CTD | PMID:33387578 | Shroom4 | Rat | paracetamol | increases expression | ISO | SHROOM4 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of SHROOM4 mRNA | CTD | PMID:26690555 | Shroom4 | Rat | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of SHROOM4 mRNA | CTD | PMID:28511854 | Shroom4 | Rat | potassium dichromate | increases expression | ISO | Shroom4 (Mus musculus) | 6480464 | Potassium Dichromate results in increased expression of SHROOM4 mRNA | CTD | PMID:23608068 | Shroom4 | Rat | resveratrol | multiple interactions | ISO | SHROOM4 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of SHROOM4 mRNA | CTD | PMID:23557933 | Shroom4 | Rat | sodium arsenate | multiple interactions | ISO | Shroom4 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Shroom4 | Rat | sodium arsenite | multiple interactions | ISO | Shroom4 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results more ... | CTD | PMID:34876320 | Shroom4 | Rat | sunitinib | decreases expression | ISO | SHROOM4 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of SHROOM4 mRNA | CTD | PMID:31533062 | Shroom4 | Rat | temozolomide | decreases expression | ISO | SHROOM4 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of SHROOM4 mRNA | CTD | PMID:31758290 | Shroom4 | Rat | titanium dioxide | increases methylation | ISO | Shroom4 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of SHROOM4 gene; titanium dioxide results in increased methylation more ... | CTD | PMID:35295148 | Shroom4 | Rat | titanium dioxide | decreases methylation | ISO | Shroom4 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of SHROOM4 gene | CTD | PMID:35295148 | Shroom4 | Rat | triphenyl phosphate | affects expression | ISO | SHROOM4 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of SHROOM4 mRNA | CTD | PMID:37042841 | Shroom4 | Rat | troglitazone | decreases expression | ISO | Shroom4 (Mus musculus) | 6480464 | troglitazone results in decreased expression of SHROOM4 mRNA | CTD | PMID:28973697 | Shroom4 | Rat | urethane | decreases expression | ISO | SHROOM4 (Homo sapiens) | 6480464 | Urethane results in decreased expression of SHROOM4 mRNA | CTD | PMID:28818685 | Shroom4 | Rat | valproic acid | decreases methylation | ISO | SHROOM4 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of SHROOM4 gene | CTD | PMID:29154799 | Shroom4 | Rat | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of SHROOM4 mRNA | CTD | PMID:29427782 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















