Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FAM110B mRNA | CTD | PMID:22079256 | 1,2-dimethylhydrazine | increases expression | ISO | Fam110b (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of FAM110B mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of FAM110B mRNA | CTD | PMID:19619570 | 17beta-estradiol | increases expression | ISO | Fam110b (Mus musculus) | 6480464 | Estradiol results in increased expression of FAM110B mRNA | CTD | PMID:19484750 | 17beta-estradiol | decreases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Estradiol results in decreased expression of FAM110B mRNA | CTD | PMID:19619570 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of FAM110B mRNA | CTD | PMID:29581250 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of FAM110B mRNA | CTD | PMID:19619570 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FAM110B mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FAM110B mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of FAM110B mRNA | CTD | PMID:20106945 and PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of FAM110B mRNA | CTD | PMID:19619570 | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:23196670 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in decreased methylation of FAM110B gene | CTD | PMID:31601247 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of FAM110B mRNA | CTD | PMID:30047161 | afimoxifene | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | afimoxifene inhibits the reaction [Estrogens results in decreased expression of FAM110B mRNA] | CTD | PMID:21233418 | aflatoxin B1 | decreases methylation | ISO | FAM110B (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of FAM110B gene | CTD | PMID:27153756 | all-trans-retinoic acid | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Tretinoin results in increased expression of FAM110B mRNA | CTD | PMID:21934132 | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of FAM110B mRNA | CTD | PMID:30047161 | arsenous acid | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of FAM110B mRNA | CTD | PMID:15761015 | atrazine | decreases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Atrazine results in decreased expression of FAM110B mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of FAM110B mRNA | CTD | PMID:20106945 and PMID:21632981 | benzo[a]pyrene | decreases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of FAM110B mRNA | CTD | PMID:32234424 | benzo[a]pyrene | decreases methylation | ISO | Fam110b (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of FAM110B exon | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | FAM110B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of FAM110B 3' UTR and Benzo(a)pyrene results in increased methylation of FAM110B 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | FAM110B (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of FAM110B promoter | CTD | PMID:27901495 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of FAM110B mRNA | CTD | PMID:24988533 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FAM110B mRNA | CTD | PMID:25181051 more ... | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of FAM110B promoter | CTD | PMID:22457795 | carbon nanotube | increases expression | ISO | Fam110b (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of FAM110B mRNA | CTD | PMID:25554681 | chloroprene | decreases expression | EXP | | 6480464 | Chloroprene results in decreased expression of FAM110B mRNA | CTD | PMID:23125180 | chromium(6+) | affects expression | ISO | FAM110B (Homo sapiens) | 6480464 | chromium hexavalent ion affects the expression of FAM110B mRNA | CTD | PMID:30690063 | cisplatin | decreases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of FAM110B mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of FAM110B mRNA | CTD | PMID:27392435 | clotrimazole | decreases expression | EXP | | 6480464 | Clotrimazole results in decreased expression of FAM110B mRNA | CTD | PMID:30047161 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of FAM110B mRNA | CTD | PMID:24386269 | copper atom | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of FAM110B mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of FAM110B mRNA | CTD | PMID:20971185 | coumestrol | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 more ... | CTD | PMID:19167446 | coumestrol | decreases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of FAM110B mRNA | CTD | PMID:19167446 | cyclosporin A | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of FAM110B mRNA | CTD | PMID:20106945 | diarsenic trioxide | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of FAM110B mRNA | CTD | PMID:15761015 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of FAM110B mRNA | CTD | PMID:21266533 | dioxygen | multiple interactions | ISO | Fam110b (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of FAM110B mRNA | CTD | PMID:30529165 | dorsomorphin | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Enterolactone | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of FAM110B mRNA | CTD | PMID:19167446 | formaldehyde | decreases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of FAM110B mRNA | CTD | PMID:23649840 | FR900359 | decreases phosphorylation | ISO | FAM110B (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of FAM110B protein | CTD | PMID:37730182 | fulvestrant | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [bisphenol S co-treated with Fulvestrant] results in decreased methylation of FAM110B gene | CTD | PMID:31601247 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of FAM110B mRNA | CTD | PMID:33387578 | glyphosate | affects methylation | EXP | | 6480464 | Glyphosate affects the methylation of FAM110B gene | CTD | PMID:35440735 | leflunomide | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | leflunomide results in increased expression of FAM110B mRNA | CTD | PMID:28988120 | melphalan | decreases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Melphalan results in decreased expression of FAM110B mRNA | CTD | PMID:22363485 | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of FAM110B mRNA | CTD | PMID:30047161 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of FAM110B gene | CTD | PMID:35440735 | panobinostat | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FAM110B mRNA | CTD | PMID:27188386 | paracetamol | decreases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of FAM110B mRNA | CTD | PMID:25704631 | paracetamol | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of FAM110B mRNA | CTD | PMID:29067470 | phenylephrine | decreases expression | EXP | | 6480464 | Phenylephrine results in decreased expression of FAM110B mRNA | CTD | PMID:18158353 | phenylmercury acetate | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of FAM110B mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FAM110B mRNA | CTD | PMID:27188386 | pirinixic acid | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of FAM110B mRNA | CTD | PMID:19710929 | potassium chromate | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of FAM110B mRNA | CTD | PMID:22079256 | potassium chromate | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of FAM110B mRNA | CTD | PMID:22714537 | potassium chromate | decreases expression | ISO | FAM110B (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of FAM110B mRNA | CTD | PMID:22079256 | quercetin | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Quercetin results in increased expression of FAM110B mRNA | CTD | PMID:21632981 | resveratrol | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in decreased expression of FAM110B mRNA | CTD | PMID:19167446 | SB 431542 | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silicon dioxide | affects expression | ISO | FAM110B (Homo sapiens) | 6480464 | Silicon Dioxide analog affects the expression of FAM110B mRNA | CTD | PMID:23806026 | sodium arsenite | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of FAM110B mRNA | CTD | PMID:22714537 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of FAM110B mRNA | CTD | PMID:19281266 | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of FAM110B mRNA | CTD | PMID:30047161 | tamoxifen | decreases expression | ISO | Fam110b (Mus musculus) | 6480464 | Tamoxifen results in decreased expression of FAM110B mRNA | CTD | PMID:17555576 and PMID:25123088 | tert-butyl hydroperoxide | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | tert-Butylhydroperoxide results in increased expression of FAM110B mRNA | CTD | PMID:29432895 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of FAM110B mRNA | CTD | PMID:34492290 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of FAM110B mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | trichostatin A results in increased expression of FAM110B mRNA | CTD | PMID:24935251 and PMID:26272509 | trichostatin A | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FAM110B mRNA | CTD | PMID:27188386 | triptonide | decreases expression | ISO | Fam110b (Mus musculus) | 6480464 | triptonide results in decreased expression of FAM110B mRNA | CTD | PMID:33045310 | valproic acid | affects expression | ISO | FAM110B (Homo sapiens) | 6480464 | Valproic Acid affects the expression of FAM110B mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | FAM110B (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of FAM110B mRNA | CTD | PMID:23179753 more ... | valproic acid | multiple interactions | ISO | FAM110B (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of FAM110B mRNA | CTD | PMID:27188386 | |