Zxda (zinc finger, X-linked, duplicated A) - Rat Genome Database

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Gene: Zxda (zinc finger, X-linked, duplicated A) Rattus norvegicus
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Symbol: Zxda
Name: zinc finger, X-linked, duplicated A
RGD ID: 1563355
Description: Predicted to enable C2H2 zinc finger domain binding activity and transcription coactivator activity. Predicted to be involved in positive regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human ZXDA (zinc finger X-linked duplicated A); INTERACTS WITH aflatoxin B1 (ortholog); amiodarone (ortholog); antirheumatic drug (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC314119; RGD1563355; similar to Zinc finger X-linked protein ZXDB; zinc finger X-linked protein ZXDB; zinc finger, X-linked, duplicated B; Zxdb
RGD Orthologs
Human
Mouse
Bonobo
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X63,770,485 - 63,775,624 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX63,771,823 - 63,775,713 (-)EnsemblGRCr8
mRatBN7.2X59,760,871 - 59,766,010 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX59,701,178 - 59,703,871 (+)EnsemblmRatBN7.2
mRatBN7.2 EnsemblX59,763,210 - 59,765,903 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX61,231,449 - 61,236,597 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X64,731,977 - 64,737,125 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X62,310,299 - 62,315,438 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X64,092,609 - 64,097,967 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X64,994,855 - 65,000,186 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X82,185,075 - 82,187,787 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX60,194,965 - 60,199,202 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOA pipeline RGD automated data pipeline
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Zxda
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X63,770,485 - 63,775,624 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX63,771,823 - 63,775,713 (-)EnsemblGRCr8
mRatBN7.2X59,760,871 - 59,766,010 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX59,701,178 - 59,703,871 (+)EnsemblmRatBN7.2
mRatBN7.2 EnsemblX59,763,210 - 59,765,903 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX61,231,449 - 61,236,597 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X64,731,977 - 64,737,125 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X62,310,299 - 62,315,438 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X64,092,609 - 64,097,967 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X64,994,855 - 65,000,186 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X82,185,075 - 82,187,787 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX60,194,965 - 60,199,202 (-)NCBICelera
Cytogenetic MapXq22NCBI
ZXDA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X57,905,430 - 57,910,458 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX57,905,430 - 57,910,458 (-)Ensemblhg38GRCh38
GRCh37X57,931,864 - 57,936,892 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X57,950,922 - 57,953,792 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34X57,817,218 - 57,820,088NCBI
CeleraX62,244,411 - 62,249,414 (+)NCBICelera
Cytogenetic MapXp11.21NCBI
HuRefX54,990,999 - 54,996,202 (-)NCBIHuRef
CHM1_1X57,922,027 - 57,927,230 (-)NCBICHM1_1
T2T-CHM13v2.0X57,205,099 - 57,210,129 (-)NCBIT2T-CHM13v2.0
Zxda
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X93,834,891 - 93,841,895 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX93,839,169 - 93,841,789 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X94,791,285 - 94,798,289 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX94,795,563 - 94,798,183 (-)Ensemblmm10GRCm38
MGSCv37X92,036,624 - 92,043,628 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X91,044,005 - 91,051,428 (-)NCBIMGSCv36mm8
CeleraX81,660,991 - 81,670,753 (+)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX41.72NCBI
LOC117977599
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X59,045,882 - 59,075,677 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X59,049,487 - 59,079,283 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X49,886,917 - 49,895,562 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3

Variants

.
Variants in Zxda
27 total Variants

QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
70221Bp56Blood pressure QTL 564.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X6103585667175160Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat

Markers in Region
DXRat89  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X59,766,385 - 59,766,594 (+)MAPPERmRatBN7.2
mRatBN7.2X59,700,486 - 59,700,695 (-)MAPPERmRatBN7.2
Rnor_6.0X64,097,994 - 64,098,202NCBIRnor6.0
Rnor_5.0X65,000,240 - 65,000,448UniSTSRnor5.0
SHRSP x BN MapX17.21RGD
SHRSP x BN MapX17.21UniSTS
Cytogenetic MapXq31UniSTS
RH138443  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X59,762,810 - 59,763,053 (+)MAPPERmRatBN7.2
Rnor_6.0X64,094,549 - 64,094,791NCBIRnor6.0
Rnor_5.0X64,996,795 - 64,997,037UniSTSRnor5.0
RGSC_v3.4X82,185,090 - 82,185,332UniSTSRGSC3.4
CeleraX60,196,905 - 60,197,147UniSTS
Cytogenetic MapXq31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
hemolymphoid system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
sensory system
visual system
7 1 18 50 64 135 92 11 49 36 32 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000101855   ⟹   ENSRNOP00000086282
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX59,763,210 - 59,765,903 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000111771   ⟹   ENSRNOP00000095925
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX59,701,178 - 59,703,871 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000158399   ⟹   ENSRNOP00000105501
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX63,771,823 - 63,775,713 (-)Ensembl
RefSeq Acc Id: NM_001402146   ⟹   NP_001389075
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X63,770,485 - 63,775,624 (-)NCBI
mRatBN7.2X59,760,871 - 59,766,010 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001389075 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000105501.1
Ensembl Acc Id: ENSRNOP00000086282   ⟸   ENSRNOT00000101855
RefSeq Acc Id: NP_001389075   ⟸   NM_001402146
- UniProtKB: A0A8I6AQ43 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000095925   ⟸   ENSRNOT00000111771
Ensembl Acc Id: ENSRNOP00000105501   ⟸   ENSRNOT00000158399

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563355 AgrOrtholog
BioCyc Gene G2FUF-2218 BioCyc
Ensembl Genes ENSRNOG00000067786 Ensembl
  ENSRNOG00000070035 Ensembl
  ENSRNOG00000084873 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000158399.1 UniProtKB/TrEMBL
NCBI Gene 314119 ENTREZGENE
PhenoGen Zxda PhenoGen
RatGTEx ENSRNOG00000067786 RatGTEx
  ENSRNOG00000070035 RatGTEx
  ENSRNOG00000084873 RatGTEx
UniProt A0A8I6AQ43 ENTREZGENE
  A0ABK0LIH8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-10 Zxda  zinc finger, X-linked, duplicated A  Zxdb  zinc finger, X-linked, duplicated B  Name and Symbol changed 629549 APPROVED
2013-05-24 Zxdb  zinc finger, X-linked, duplicated B  LOC683516  similar to Zinc finger X-linked protein ZXDB  Data merged from RGD:1585677 1643240 APPROVED
2010-05-05 Zxdb  zinc finger, X-linked, duplicated B  RGD1563355  similar to Zinc finger X-linked protein ZXDB  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1563355  similar to Zinc finger X-linked protein ZXDB   RGD1563355_predicted  similar to Zinc finger X-linked protein ZXDB (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-19 LOC683516  similar to Zinc finger X-linked protein ZXDB      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-03-07 RGD1563355_predicted  similar to Zinc finger X-linked protein ZXDB (predicted)  LOC314119  similar to Zinc finger X-linked protein ZXDB  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC314119  similar to Zinc finger X-linked protein ZXDB      Symbol and Name status set to provisional 70820 PROVISIONAL