Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tmem164 | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | TMEM164 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TMEM164 mRNA | CTD | PMID:22079256 | Tmem164 | Rat | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of TMEM164 mRNA | CTD | PMID:17351261 | Tmem164 | Rat | 17beta-estradiol | decreases expression | ISO | Tmem164 (Mus musculus) | 6480464 | Estradiol results in decreased expression of TMEM164 mRNA | CTD | PMID:39298647 | Tmem164 | Rat | 17beta-estradiol | increases expression | ISO | TMEM164 (Homo sapiens) | 6480464 | Estradiol results in increased expression of TMEM164 mRNA | CTD | PMID:31614463 | Tmem164 | Rat | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | TMEM164 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of TMEM164 mRNA | CTD | PMID:29581250 | Tmem164 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tmem164 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TMEM164 mRNA | CTD | PMID:21570461 | Tmem164 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TMEM164 mRNA | CTD | PMID:33387578 | Tmem164 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TMEM164 mRNA | CTD | PMID:34747641 | Tmem164 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Tmem164 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of TMEM164 mRNA | CTD | PMID:39298647 | Tmem164 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Tmem164 (Mus musculus) | 6480464 | Fenretinide results in increased expression of TMEM164 mRNA | CTD | PMID:28973697 | Tmem164 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of TMEM164 mRNA | CTD | PMID:24780913 | Tmem164 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TMEM164 mRNA | CTD | PMID:30047161 | Tmem164 | Rat | aflatoxin B1 | decreases expression | ISO | Tmem164 (Mus musculus) | 6480464 | Aflatoxin B1 results in decreased expression of TMEM164 mRNA | CTD | PMID:19770486 | Tmem164 | Rat | Aflatoxin B2 alpha | increases methylation | ISO | TMEM164 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of TMEM164 intron | CTD | PMID:30157460 | Tmem164 | Rat | all-trans-retinoic acid | increases expression | ISO | TMEM164 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of TMEM164 mRNA | CTD | PMID:33167477 | Tmem164 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of TMEM164 mRNA | CTD | PMID:30047161 | Tmem164 | Rat | aristolochic acid A | decreases expression | ISO | TMEM164 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of TMEM164 mRNA | CTD | PMID:33212167 | Tmem164 | Rat | benzo[a]pyrene | decreases expression | ISO | Tmem164 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of TMEM164 mRNA | CTD | PMID:19770486|PMID:22228805 | Tmem164 | Rat | benzo[a]pyrene | decreases methylation | ISO | Tmem164 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of TMEM164 intron | CTD | PMID:27901495 | Tmem164 | Rat | benzo[a]pyrene | increases methylation | ISO | TMEM164 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TMEM164 5' UTR | CTD | PMID:27901495 | Tmem164 | Rat | benzo[a]pyrene | affects methylation | ISO | TMEM164 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TMEM164 exon; Benzo(a)pyrene affects the methylation of TMEM164 promoter | CTD | PMID:27901495 | Tmem164 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Tmem164 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of TMEM164 mRNA | CTD | PMID:34319233 | Tmem164 | Rat | bisphenol A | decreases expression | ISO | Tmem164 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of TMEM164 mRNA | CTD | PMID:26063408 | Tmem164 | Rat | bisphenol A | increases expression | ISO | Tmem164 (Mus musculus) | 6480464 | bisphenol A results in increased expression of TMEM164 mRNA | CTD | PMID:37105096 | Tmem164 | Rat | bisphenol A | increases methylation | ISO | TMEM164 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of TMEM164 gene | CTD | PMID:31601247 | Tmem164 | Rat | bisphenol A | decreases methylation | ISO | Tmem164 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of TMEM164 promoter | CTD | PMID:27312807 | Tmem164 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of TMEM164 gene | CTD | PMID:28505145 | Tmem164 | Rat | bisphenol A | increases expression | ISO | TMEM164 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of TMEM164 mRNA | CTD | PMID:29275510 | Tmem164 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TMEM164 mRNA | CTD | PMID:25181051 | Tmem164 | Rat | bisphenol F | increases expression | ISO | Tmem164 (Mus musculus) | 6480464 | bisphenol F results in increased expression of TMEM164 mRNA | CTD | PMID:38685157 | Tmem164 | Rat | carbon nanotube | decreases expression | ISO | Tmem164 (Mus musculus) | 6480464 | Nanotubes, Carbon results in decreased expression of TMEM164 mRNA | CTD | PMID:25620056 | Tmem164 | Rat | chlorpyrifos | decreases expression | ISO | Tmem164 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of TMEM164 mRNA | CTD | PMID:32715474 | Tmem164 | Rat | coumestrol | multiple interactions | ISO | TMEM164 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TMEM164 mRNA; [Coumestrol co-treated with resveratrol] more ... | CTD | PMID:19167446 | Tmem164 | Rat | cyclosporin A | decreases expression | ISO | TMEM164 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TMEM164 mRNA | CTD | PMID:27989131 | Tmem164 | Rat | dextran sulfate | decreases expression | ISO | Tmem164 (Mus musculus) | 6480464 | Dextran Sulfate results in decreased expression of TMEM164 mRNA | CTD | PMID:35093514 | Tmem164 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of TMEM164 mRNA | CTD | PMID:21266533 | Tmem164 | Rat | doxorubicin | decreases expression | ISO | TMEM164 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TMEM164 mRNA | CTD | PMID:29803840 | Tmem164 | Rat | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of TMEM164 mRNA | CTD | PMID:29391264 | Tmem164 | Rat | Enterolactone | multiple interactions | ISO | TMEM164 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of TMEM164 mRNA | CTD | PMID:19167446 | Tmem164 | Rat | ethanol | increases expression | ISO | Tmem164 (Mus musculus) | 6480464 | Ethanol results in increased expression of TMEM164 mRNA | CTD | PMID:30319688 | Tmem164 | Rat | fluoranthene | multiple interactions | ISO | Tmem164 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in decreased expression of TMEM164 mRNA | CTD | PMID:28329830 | Tmem164 | Rat | FR900359 | increases phosphorylation | ISO | TMEM164 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of TMEM164 protein | CTD | PMID:37730182 | Tmem164 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of TMEM164 mRNA | CTD | PMID:33387578 | Tmem164 | Rat | indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of TMEM164 mRNA | CTD | PMID:22129741 | Tmem164 | Rat | isoprenaline | increases expression | ISO | Tmem164 (Mus musculus) | 6480464 | Isoproterenol results in increased expression of TMEM164 mRNA | CTD | PMID:20003209 | Tmem164 | Rat | isotretinoin | decreases expression | ISO | TMEM164 (Homo sapiens) | 6480464 | Isotretinoin results in decreased expression of TMEM164 mRNA | CTD | PMID:20436886 | Tmem164 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of TMEM164 mRNA | CTD | PMID:22129741 | Tmem164 | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of TMEM164 mRNA | CTD | PMID:32680482 | Tmem164 | Rat | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of TMEM164 mRNA | CTD | PMID:30047161 | Tmem164 | Rat | pirinixic acid | increases expression | ISO | Tmem164 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of TMEM164 mRNA | CTD | PMID:23811191 | Tmem164 | Rat | potassium chromate | decreases expression | ISO | TMEM164 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of TMEM164 mRNA | CTD | PMID:22079256 | Tmem164 | Rat | potassium chromate | multiple interactions | ISO | TMEM164 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TMEM164 mRNA | CTD | PMID:22079256 | Tmem164 | Rat | pravastatin | decreases expression | EXP | | 6480464 | Pravastatin results in decreased expression of TMEM164 mRNA | CTD | PMID:27225895 | Tmem164 | Rat | pravastatin | increases expression | ISO | Tmem164 (Mus musculus) | 6480464 | Pravastatin results in increased expression of TMEM164 mRNA | CTD | PMID:27225895 | Tmem164 | Rat | progesterone | increases expression | ISO | TMEM164 (Homo sapiens) | 6480464 | Progesterone results in increased expression of TMEM164 mRNA | CTD | PMID:21795739 | Tmem164 | Rat | propanal | increases expression | ISO | TMEM164 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of TMEM164 mRNA | CTD | PMID:26079696 | Tmem164 | Rat | resveratrol | multiple interactions | ISO | TMEM164 (Homo sapiens) | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of TMEM164 mRNA | CTD | PMID:19167446 | Tmem164 | Rat | sodium arsenite | decreases methylation | ISO | Tmem164 (Mus musculus) | 6480464 | sodium arsenite results in decreased methylation of TMEM164 gene | CTD | PMID:39894169 | Tmem164 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of TMEM164 mRNA | CTD | PMID:19281266 | Tmem164 | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of TMEM164 mRNA | CTD | PMID:30047161 | Tmem164 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of TMEM164 mRNA | CTD | PMID:31150632 | Tmem164 | Rat | tetrachloromethane | decreases expression | ISO | Tmem164 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of TMEM164 mRNA | CTD | PMID:31919559 | Tmem164 | Rat | titanium dioxide | increases methylation | ISO | Tmem164 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of TMEM164 gene; titanium dioxide results in increased methylation more ... | CTD | PMID:35295148 | Tmem164 | Rat | titanium dioxide | decreases methylation | ISO | Tmem164 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TMEM164 gene | CTD | PMID:35295148 | Tmem164 | Rat | triphenyl phosphate | affects expression | ISO | TMEM164 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of TMEM164 mRNA | CTD | PMID:37042841 | Tmem164 | Rat | triptonide | increases expression | ISO | Tmem164 (Mus musculus) | 6480464 | triptonide results in increased expression of TMEM164 mRNA | CTD | PMID:33045310 | Tmem164 | Rat | tris(2-butoxyethyl) phosphate | affects expression | ISO | TMEM164 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of TMEM164 mRNA | CTD | PMID:29024780 | Tmem164 | Rat | valproic acid | increases methylation | ISO | TMEM164 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of TMEM164 gene | CTD | PMID:29154799 | Tmem164 | Rat | valproic acid | decreases expression | ISO | Tmem164 (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of TMEM164 mRNA | CTD | PMID:20546886 | Tmem164 | Rat | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of TMEM164 gene | CTD | PMID:31682807 | Tmem164 | Rat | zaragozic acid A | decreases expression | EXP | | 6480464 | squalestatin 1 results in decreased expression of TMEM164 mRNA | CTD | PMID:27225895 | Tmem164 | Rat | zaragozic acid A | decreases expression | ISO | Tmem164 (Mus musculus) | 6480464 | squalestatin 1 results in decreased expression of TMEM164 mRNA | CTD | PMID:27225895 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















