Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tspyl2 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Tspyl2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of TSPYL2 mRNA] | CTD | PMID:22206623 | Tspyl2 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of TSPYL2 mRNA | CTD | PMID:22206623 | Tspyl2 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Tspyl2 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of TSPYL2 mRNA | CTD | PMID:17555576 | Tspyl2 | Rat | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of TSPYL2 mRNA | CTD | PMID:26496021 | Tspyl2 | Rat | 17beta-estradiol | increases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | Estradiol results in increased expression of TSPYL2 mRNA | CTD | PMID:39298647 | Tspyl2 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Tspyl2 (Mus musculus) | 6480464 | 2,2',4,4'-tetrabromodiphenyl ether affects the expression of TSPYL2 mRNA | CTD | PMID:30294300 | Tspyl2 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | TSPYL2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Tspyl2 | Rat | 4-hydroxynon-2-enal | decreases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of TSPYL2 mRNA | CTD | PMID:19191707 | Tspyl2 | Rat | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of TSPYL2 mRNA | CTD | PMID:28959563 | Tspyl2 | Rat | acrylamide | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of TSPYL2 mRNA | CTD | PMID:32763439 | Tspyl2 | Rat | amiodarone | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of TSPYL2 mRNA | CTD | PMID:19774075 | Tspyl2 | Rat | aristolochic acid A | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of TSPYL2 mRNA | CTD | PMID:33212167 | Tspyl2 | Rat | Aroclor 1254 | decreases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of TSPYL2 mRNA | CTD | PMID:23650126 | Tspyl2 | Rat | arsane | multiple interactions | ISO | TSPYL2 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TSPYL2 more ... | CTD | PMID:39836092 | Tspyl2 | Rat | arsenic atom | multiple interactions | ISO | TSPYL2 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TSPYL2 more ... | CTD | PMID:39836092 | Tspyl2 | Rat | arsenous acid | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of TSPYL2 mRNA | CTD | PMID:27829220 | Tspyl2 | Rat | benzo[a]pyrene | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of TSPYL2 mRNA | CTD | PMID:22316170 | Tspyl2 | Rat | benzo[a]pyrene | affects methylation | ISO | TSPYL2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TSPYL2 exon; Benzo(a)pyrene affects the methylation of TSPYL2 promoter | CTD | PMID:27901495 | Tspyl2 | Rat | benzo[a]pyrene | decreases methylation | ISO | TSPYL2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of TSPYL2 3' UTR | CTD | PMID:27901495 | Tspyl2 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of TSPYL2 mRNA | CTD | PMID:20382639 | Tspyl2 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of TSPYL2 mRNA | CTD | PMID:31163220 | Tspyl2 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of TSPYL2 mRNA | CTD | PMID:34319233 | Tspyl2 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of TSPYL2 mRNA | CTD | PMID:33162236 | Tspyl2 | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of TSPYL2 mRNA | CTD | PMID:26496021 | Tspyl2 | Rat | bisphenol A | decreases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of TSPYL2 mRNA | CTD | PMID:32156529|PMID:33221593 | Tspyl2 | Rat | bisphenol A | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of TSPYL2 mRNA | CTD | PMID:29275510 | Tspyl2 | Rat | bisphenol A | affects methylation | ISO | Tspyl2 (Mus musculus) | 6480464 | bisphenol A affects the methylation of TSPYL2 promoter | CTD | PMID:27334623 | Tspyl2 | Rat | bisphenol A | increases methylation | ISO | Tspyl2 (Mus musculus) | 6480464 | bisphenol A results in increased methylation of TSPYL2 promoter | CTD | PMID:27312807 | Tspyl2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TSPYL2 mRNA | CTD | PMID:25181051|PMID:30816183|PMID:41034487 | Tspyl2 | Rat | bisphenol F | multiple interactions | ISO | TSPYL2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Tspyl2 | Rat | bisphenol F | decreases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of TSPYL2 mRNA | CTD | PMID:38685157 | Tspyl2 | Rat | cadmium dichloride | decreases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of TSPYL2 mRNA | CTD | PMID:38382870 | Tspyl2 | Rat | cadmium dichloride | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of TSPYL2 mRNA | CTD | PMID:38568856 | Tspyl2 | Rat | carbon nanotube | decreases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | Nanotubes, Carbon results in decreased expression of TSPYL2 mRNA | CTD | PMID:25554681 | Tspyl2 | Rat | cisplatin | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of TSPYL2 mRNA | CTD | PMID:27594783 | Tspyl2 | Rat | cobalt dichloride | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of TSPYL2 mRNA | CTD | PMID:19320972 | Tspyl2 | Rat | copper atom | multiple interactions | ISO | TSPYL2 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of TSPYL2 mRNA | CTD | PMID:24690739 | Tspyl2 | Rat | copper(0) | multiple interactions | ISO | TSPYL2 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of TSPYL2 mRNA | CTD | PMID:24690739 | Tspyl2 | Rat | copper(II) sulfate | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of TSPYL2 mRNA | CTD | PMID:19549813 | Tspyl2 | Rat | crocidolite asbestos | decreases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | Asbestos, Crocidolite results in decreased expression of TSPYL2 mRNA | CTD | PMID:29279043 | Tspyl2 | Rat | cyclosporin A | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TSPYL2 mRNA | CTD | PMID:20106945|PMID:21632981|PMID:25562108 | Tspyl2 | Rat | DDE | decreases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in decreased expression of TSPYL2 mRNA | CTD | PMID:38568856 | Tspyl2 | Rat | dexamethasone | multiple interactions | ISO | TSPYL2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Tspyl2 | Rat | diarsenic trioxide | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of TSPYL2 mRNA | CTD | PMID:27829220 | Tspyl2 | Rat | Dibutyl phosphate | affects expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TSPYL2 mRNA | CTD | PMID:37042841 | Tspyl2 | Rat | dichloroacetic acid | decreases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | Dichloroacetic Acid results in decreased expression of TSPYL2 mRNA | CTD | PMID:28962523 | Tspyl2 | Rat | disulfiram | multiple interactions | ISO | TSPYL2 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of TSPYL2 mRNA | CTD | PMID:24690739 | Tspyl2 | Rat | doxorubicin | decreases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TSPYL2 mRNA | CTD | PMID:29803840 | Tspyl2 | Rat | doxorubicin | increases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | Doxorubicin results in increased expression of TSPYL2 mRNA | CTD | PMID:39631538 | Tspyl2 | Rat | ethanol | affects splicing | ISO | Tspyl2 (Mus musculus) | 6480464 | Ethanol affects the splicing of TSPYL2 mRNA | CTD | PMID:30319688 | Tspyl2 | Rat | folic acid | multiple interactions | ISO | Tspyl2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1,2-Dimethylhydrazine results in decreased expression of TSPYL2 mRNA] | CTD | PMID:22206623 | Tspyl2 | Rat | formaldehyde | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of TSPYL2 mRNA | CTD | PMID:17938736 | Tspyl2 | Rat | indometacin | multiple interactions | ISO | TSPYL2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... | CTD | PMID:28628672 | Tspyl2 | Rat | menadione | affects expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of TSPYL2 mRNA | CTD | PMID:20044591 | Tspyl2 | Rat | methylisothiazolinone | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased expression of TSPYL2 mRNA | CTD | PMID:31629900 | Tspyl2 | Rat | nickel atom | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Nickel results in increased expression of TSPYL2 mRNA | CTD | PMID:23195993 | Tspyl2 | Rat | okadaic acid | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Okadaic Acid results in increased expression of TSPYL2 mRNA | CTD | PMID:38832940 | Tspyl2 | Rat | ozone | multiple interactions | ISO | Tspyl2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... | CTD | PMID:34911549 | Tspyl2 | Rat | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of TSPYL2 mRNA | CTD | PMID:28903501 | Tspyl2 | Rat | propanal | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of TSPYL2 mRNA | CTD | PMID:26079696 | Tspyl2 | Rat | quercetin | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Quercetin results in increased expression of TSPYL2 mRNA | CTD | PMID:21632981 | Tspyl2 | Rat | resveratrol | multiple interactions | ISO | TSPYL2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of TSPYL2 mRNA | CTD | PMID:23557933 | Tspyl2 | Rat | silicon dioxide | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of TSPYL2 mRNA | CTD | PMID:25895662 | Tspyl2 | Rat | silicon dioxide | increases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | Silicon Dioxide results in increased expression of TSPYL2 mRNA | CTD | PMID:23221170 | Tspyl2 | Rat | sodium arsenite | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of TSPYL2 mRNA | CTD | PMID:38568856 | Tspyl2 | Rat | sodium arsenite | multiple interactions | ISO | TSPYL2 (Homo sapiens) | 6480464 | [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TSPYL2 more ... | CTD | PMID:39836092 | Tspyl2 | Rat | sodium arsenite | decreases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of TSPYL2 mRNA | CTD | PMID:34032870 | Tspyl2 | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of TSPYL2 mRNA | CTD | PMID:19281266 | Tspyl2 | Rat | tamoxifen | affects expression | ISO | Tspyl2 (Mus musculus) | 6480464 | Tamoxifen affects the expression of TSPYL2 mRNA | CTD | PMID:17555576 | Tspyl2 | Rat | thiram | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Thiram results in increased expression of TSPYL2 mRNA | CTD | PMID:38568856 | Tspyl2 | Rat | titanium dioxide | increases methylation | ISO | Tspyl2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of TSPYL2 promoter | CTD | PMID:35295148 | Tspyl2 | Rat | titanium dioxide | decreases methylation | ISO | Tspyl2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TSPYL2 gene | CTD | PMID:35295148 | Tspyl2 | Rat | trichostatin A | affects expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | trichostatin A affects the expression of TSPYL2 mRNA | CTD | PMID:28542535 | Tspyl2 | Rat | triptonide | increases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | triptonide results in increased expression of TSPYL2 mRNA | CTD | PMID:33045310 | Tspyl2 | Rat | trovafloxacin | increases expression | ISO | Tspyl2 (Mus musculus) | 6480464 | trovafloxacin results in increased expression of TSPYL2 mRNA | CTD | PMID:35537566 | Tspyl2 | Rat | urethane | increases expression | ISO | TSPYL2 (Homo sapiens) | 6480464 | Urethane results in increased expression of TSPYL2 mRNA | CTD | PMID:28818685 | Tspyl2 | Rat | zinc atom | multiple interactions | ISO | TSPYL2 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of TSPYL2 mRNA | CTD | PMID:18593933 | Tspyl2 | Rat | zinc(0) | multiple interactions | ISO | TSPYL2 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of TSPYL2 mRNA | CTD | PMID:18593933 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















