Rspo3 (R-spondin 3) - Rat Genome Database

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Gene: Rspo3 (R-spondin 3) Rattus norvegicus
Analyze
Symbol: Rspo3
Name: R-spondin 3
RGD ID: 1563246
Description: Predicted to enable frizzled binding activity and heparin binding activity. Predicted to be involved in blood vessel remodeling; positive regulation of Wnt signaling pathway; and sprouting angiogenesis. Predicted to act upstream of or within angiogenesis and branching involved in labyrinthine layer morphogenesis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human RSPO3 (R-spondin 3); PARTICIPATES IN Wnt signaling, canonical pathway; INTERACTS WITH 6-propyl-2-thiouracil; acetamide; amitrole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC498997; R-spondin 3 homolog; R-spondin 3 homolog (Xenopus laevis); R-spondin 3-like protein; R-spondin-3; RGD1563246; similar to thrombospondin, type I, domain containing 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,112,529 - 30,197,267 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl130,112,114 - 30,197,938 (+)EnsemblGRCr8
mRatBN7.2128,283,914 - 28,368,661 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl128,283,914 - 28,367,061 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx128,065,317 - 28,155,972 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0134,065,172 - 34,155,823 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0128,265,937 - 28,356,592 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0130,681,648 - 30,768,038 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl130,681,681 - 30,766,860 (+)Ensemblrn6Rnor6.0
Rnor_5.0132,115,437 - 32,200,578 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4129,072,171 - 29,156,096 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera126,951,713 - 27,034,597 (+)NCBICelera
Cytogenetic Map1p11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetaldehyde  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
amitrole  (EXP)
Aroclor 1254  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
Cuprizon  (EXP)
diarsenic trioxide  (ISO)
dioxygen  (EXP,ISO)
dorsomorphin  (ISO)
flusilazole  (ISO)
fulvestrant  (ISO)
inulin  (ISO)
lead diacetate  (EXP)
methidathion  (ISO)
methimazole  (EXP)
methylmercury chloride  (ISO)
N(4)-hydroxycytidine  (ISO)
N-nitrosodiethylamine  (ISO)
naled  (ISO)
nickel atom  (ISO)
nicotine  (ISO)
okadaic acid  (ISO)
p-chloromercuribenzoic acid  (ISO)
panobinostat  (ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
quercetin  (EXP)
rifampicin  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
succimer  (ISO)
sulforaphane  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The complex world of WNT receptor signalling. Niehrs C Nat Rev Mol Cell Biol. 2012 Dec;13(12):767-79. doi: 10.1038/nrm3470. Epub 2012 Nov 15.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:16543246   PMID:16963017   PMID:18842812   PMID:22615920   PMID:24280058   PMID:26766444   PMID:29769720  


Genomics

Comparative Map Data
Rspo3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8130,112,529 - 30,197,267 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl130,112,114 - 30,197,938 (+)EnsemblGRCr8
mRatBN7.2128,283,914 - 28,368,661 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl128,283,914 - 28,367,061 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx128,065,317 - 28,155,972 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0134,065,172 - 34,155,823 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0128,265,937 - 28,356,592 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0130,681,648 - 30,768,038 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl130,681,681 - 30,766,860 (+)Ensemblrn6Rnor6.0
Rnor_5.0132,115,437 - 32,200,578 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4129,072,171 - 29,156,096 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera126,951,713 - 27,034,597 (+)NCBICelera
Cytogenetic Map1p11NCBI
RSPO3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386127,118,671 - 127,199,481 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6127,118,663 - 127,199,481 (+)Ensemblhg38GRCh38
GRCh376127,439,816 - 127,520,626 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366127,481,741 - 127,559,877 (+)NCBIBuild 36Build 36hg18NCBI36
Build 346127,481,748 - 127,559,877NCBI
Celera6128,182,296 - 128,260,461 (+)NCBICelera
Cytogenetic Map6q22.33NCBI
HuRef6125,016,583 - 125,097,147 (+)NCBIHuRef
CHM1_16127,704,346 - 127,784,940 (+)NCBICHM1_1
T2T-CHM13v2.06128,307,592 - 128,388,425 (+)NCBIT2T-CHM13v2.0
Rspo3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391029,329,102 - 29,411,863 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1029,328,412 - 29,411,863 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381029,453,106 - 29,535,867 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1029,452,416 - 29,535,867 (-)Ensemblmm10GRCm38
MGSCv371029,172,912 - 29,255,673 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361029,142,522 - 29,225,241 (-)NCBIMGSCv36mm8
Celera1030,384,889 - 30,467,440 (-)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1016.64NCBI
Rspo3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554368,151,122 - 8,237,861 (+)Ensembl
ChiLan1.0NW_0049554368,151,122 - 8,235,183 (+)NCBIChiLan1.0ChiLan1.0
RSPO3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25147,112,600 - 147,191,650 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16145,017,872 - 145,096,936 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06124,906,783 - 124,985,758 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16129,023,146 - 129,100,194 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6129,023,450 - 129,101,695 (+)EnsemblpanPan2panpan1.1
RSPO3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1165,858,822 - 65,936,160 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl165,858,794 - 65,936,322 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha166,658,296 - 66,742,223 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0166,049,403 - 66,133,135 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl166,047,221 - 66,133,297 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1165,985,735 - 66,069,341 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0165,764,149 - 65,847,921 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0166,412,775 - 66,496,470 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Rspo3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946115,866,440 - 115,944,414 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366392,475,710 - 2,552,725 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366392,475,710 - 2,552,725 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RSPO3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl135,984,950 - 36,067,077 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1135,985,985 - 36,066,432 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2139,747,136 - 39,787,103 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RSPO3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11346,530,423 - 46,606,900 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1346,530,355 - 46,606,730 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604018,808,306 - 18,891,654 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rspo3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247531,520,210 - 1,600,432 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247531,520,337 - 1,600,054 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Rspo3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v155,580,500 - 5,617,681 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Rspo3
796 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:94
Count of miRNA genes:81
Interacting mature miRNAs:86
Transcripts:ENSRNOT00000015395
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313090Bmd69Bone mineral density QTL 694.40.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)1529322934184556Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1774611852746118Rat
4889451Eae29Experimental allergic encephalomyelitis QTL 295.51nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1774612152746121Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12940927974409279Rat
70179Xhs2X-ray hypersensitivity QTL 23.2intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)1143965634Rat
1558642Prcr2Prostate cancer resistance QTL 24.3prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)11037949255379492Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1694102251941022Rat
2313070Bss52Bone structure and strength QTL 524.40.0001body length (VT:0001256)body length (CMO:0000013)1529322934184556Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)1690935351909353Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11731537851816258Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)1690935351909353Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)1690935351909353Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11282049457820494Rat
2317755Glom22Glomerulus QTL 223.8urine protein amount (VT:0005160)urine protein level (CMO:0000591)1134184556Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)12065642065656420Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)12050832665508326Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)11168446456684464Rat
2313053Bss51Bone structure and strength QTL 513.80.0001tibia length (VT:0004357)tibia length (CMO:0000450)1529322934184556Rat

Markers in Region
D1Got34  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2128,331,162 - 28,331,462 (+)MAPPERmRatBN7.2
Rnor_6.0130,729,174 - 30,729,473NCBIRnor6.0
Rnor_5.0132,162,888 - 32,163,187UniSTSRnor5.0
RGSC_v3.4129,119,714 - 29,120,014RGDRGSC3.4
RGSC_v3.4129,119,715 - 29,120,014UniSTSRGSC3.4
Celera126,998,764 - 26,999,063UniSTS
RGSC_v3.1129,122,660 - 29,122,959RGD
RH 3.4 Map1321.4UniSTS
RH 3.4 Map1321.4RGD
RH 2.0 Map1202.5RGD
Cytogenetic Map1p11UniSTS
BM384382  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr8130,189,135 - 30,189,295 (+)Marker Load Pipeline
mRatBN7.2128,360,527 - 28,360,687 (+)MAPPERmRatBN7.2
Rnor_6.0130,758,629 - 30,758,788NCBIRnor6.0
Rnor_5.0132,192,447 - 32,192,606UniSTSRnor5.0
RGSC_v3.4129,149,565 - 29,149,724UniSTSRGSC3.4
Celera127,028,066 - 27,028,225UniSTS
RH 3.4 Map1322.8UniSTS
Cytogenetic Map1p11UniSTS
BE111437  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2128,320,178 - 28,320,361 (+)MAPPERmRatBN7.2
Rnor_6.0130,718,311 - 30,718,493NCBIRnor6.0
Rnor_5.0132,152,105 - 32,152,287UniSTSRnor5.0
RGSC_v3.4129,108,433 - 29,108,615UniSTSRGSC3.4
Celera126,987,975 - 26,988,157UniSTS
RH 3.4 Map1317.7UniSTS
Cytogenetic Map1p11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
10 12 61 131 91 89 59 25 59 6 259 119 11 107 63 91 30 6 6

Sequence


Ensembl Acc Id: ENSRNOT00000015395   ⟹   ENSRNOP00000015395
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl130,112,114 - 30,196,071 (+)Ensembl
mRatBN7.2 Ensembl128,283,914 - 28,367,061 (+)Ensembl
Rnor_6.0 Ensembl130,681,681 - 30,766,860 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000137462   ⟹   ENSRNOP00000099131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl130,112,114 - 30,197,938 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000155119   ⟹   ENSRNOP00000101906
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl130,112,114 - 30,197,266 (+)Ensembl
RefSeq Acc Id: NM_001100990   ⟹   NP_001094460
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8130,112,529 - 30,195,667 (+)NCBI
mRatBN7.2128,283,914 - 28,367,061 (+)NCBI
Rnor_6.0130,682,049 - 30,765,160 (+)NCBI
Rnor_5.0132,115,437 - 32,200,578 (+)NCBI
RGSC_v3.4129,072,171 - 29,156,096 (+)RGD
Celera126,951,713 - 27,034,597 (+)RGD
Sequence:
RefSeq Acc Id: XM_017589545   ⟹   XP_017445034
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8130,112,584 - 30,197,267 (+)NCBI
mRatBN7.2128,283,970 - 28,368,661 (+)NCBI
Rnor_6.0130,681,648 - 30,768,038 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001094460 (Get FASTA)   NCBI Sequence Viewer  
  XP_017445034 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABS71125 (Get FASTA)   NCBI Sequence Viewer  
  EDL87699 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000015395.5
  ENSRNOP00000099131
  ENSRNOP00000099131.1
  ENSRNOP00000101906
  ENSRNOP00000101906.1
RefSeq Acc Id: NP_001094460   ⟸   NM_001100990
- Peptide Label: precursor
- UniProtKB: A7LKE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017445034   ⟸   XM_017589545
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000015395   ⟸   ENSRNOT00000015395
Ensembl Acc Id: ENSRNOP00000099131   ⟸   ENSRNOT00000137462
Ensembl Acc Id: ENSRNOP00000101906   ⟸   ENSRNOT00000155119
Protein Domains
R-spondin Fu-CRD   Spondin-like TSP1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A7LKE6-F1-model_v2 AlphaFold A7LKE6 1-276 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689547
Promoter ID:EPDNEW_R71
Type:single initiation site
Name:Rspo3_1
Description:R-spondin 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0130,681,644 - 30,681,704EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563246 AgrOrtholog
BioCyc Gene G2FUF-61963 BioCyc
Ensembl Genes ENSRNOG00000011568 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000015395.7 UniProtKB/TrEMBL
  ENSRNOT00000137462 ENTREZGENE
  ENSRNOT00000137462.1 UniProtKB/TrEMBL
  ENSRNOT00000155119 ENTREZGENE
  ENSRNOT00000155119.1 UniProtKB/TrEMBL
Gene3D-CATH 2.20.100.10 UniProtKB/TrEMBL
  Hormone Receptor, Insulin-like Growth Factor Receptor 1, Chain A, domain 2 UniProtKB/TrEMBL
InterPro Furin_repeat UniProtKB/TrEMBL
  Growth_fac_rcpt UniProtKB/TrEMBL
  R-spondin UniProtKB/TrEMBL
  Rspo_Fu-CRD_dom UniProtKB/TrEMBL
  Thrombospondin_1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
  TSP1_spondin_dom UniProtKB/TrEMBL
KEGG Report rno:498997 UniProtKB/TrEMBL
NCBI Gene 498997 ENTREZGENE
PANTHER NEUROHYPOPHYSIAL HORMONES, N-TERMINAL DOMAIN CONTAINING PROTEIN UniProtKB/TrEMBL
  PTHR46987:SF1 UniProtKB/TrEMBL
Pfam Furin-like_2 UniProtKB/TrEMBL
  TSP1_spondin UniProtKB/TrEMBL
PhenoGen Rspo3 PhenoGen
PROSITE TSP1 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011568 RatGTEx
SMART SM00261 UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
Superfamily-SCOP Grow_fac_recept UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
UniProt A0ABK0L8S9_RAT UniProtKB/TrEMBL
  A7LKE6 ENTREZGENE, UniProtKB/TrEMBL
  F7F4H8_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-01 Rspo3  R-spondin 3  Rspo3  R-spondin 3 homolog (Xenopus laevis)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Rspo3  R-spondin 3 homolog (Xenopus laevis)  RGD1563246_predicted  similar to thrombospondin, type I, domain containing 2 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1563246_predicted  similar to thrombospondin, type I, domain containing 2 (predicted)  LOC498997  similar to thrombospondin, type I, domain containing 2  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC498997  similar to thrombospondin, type I, domain containing 2      Symbol and Name status set to provisional 70820 PROVISIONAL