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Gene: Gpr161 (G protein-coupled receptor 161) Rattus norvegicus

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Symbol:

Gpr161

Name:

G protein-coupled receptor 161

RGD ID:

1563245

Description:

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning. Predicted to be located in cilium; glial cell projection; and neuron projection. Predicted to be active in recycling endosome. Human ortholog(s) of this gene implicated in medulloblastoma. Orthologous to human GPR161 (G protein-coupled receptor 161); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

G-protein coupled receptor 161; LOC289180; RGD1563245; similar to G protein-coupled receptor 161

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GPR161 (G protein-coupled receptor 161)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Gpr161 (G protein-coupled receptor 161)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gpr161 (G protein-coupled receptor 161)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GPR161 (G protein-coupled receptor 161)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GPR161 (G protein-coupled receptor 161)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gpr161 (G protein-coupled receptor 161)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GPR161 (G protein-coupled receptor 161)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GPR161 (G protein-coupled receptor 161)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gpr161 (G protein-coupled receptor 161)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Gpr161 (G protein-coupled receptor 161)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Gpr161 (G protein-coupled receptor 161)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GPR161 (G protein-coupled receptor 161)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:ch211-237c6.4	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|SonicParanoid)
Danio rerio (zebrafish):	gpr161 (G protein-coupled receptor 161)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	gpr161	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	80,111,271 - 80,156,517 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	80,117,114 - 80,152,861 (+)	Ensembl				GRCr8
mRatBN7.2	13	77,578,257 - 77,623,661 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	77,577,739 - 77,619,613 (+)	Ensembl				mRatBN7.2
Rnor_6.0	13	83,530,389 - 83,576,117 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	83,531,018 - 83,571,505 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	88,409,782 - 88,455,575 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	81,053,624 - 81,074,896 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	77,290,655 - 77,336,787 (+)	NCBI		Celera
Cytogenetic Map	13	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Desbuquois dysplasia (ISO)

gastrointestinal stromal tumor (ISO)

medulloblastoma (ISO)

Pituitary Stalk Interruption Syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

antirheumatic drug (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

chlordecone (ISO)

copper atom (EXP,ISO)

copper(0) (EXP,ISO)

Cuprizon (EXP)

dimethyl sulfoxide (ISO)

disodium selenite (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

epoxiconazole (ISO)

folic acid (ISO)

FR900359 (ISO)

glycidol (EXP)

glyphosate (EXP)

isoflurane (ISO)

Lasiocarpine (ISO)

lipopolysaccharide (ISO)

methoxychlor (EXP)

methylseleninic acid (ISO)

N-Nitrosopyrrolidine (ISO)

nitrofen (EXP)

ozone (ISO)

paracetamol (ISO)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

sevoflurane (ISO)

sodium arsenite (ISO)

tert-butyl hydroperoxide (ISO)

thiram (ISO)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-activating G protein-coupled receptor signaling pathway (IBA,ISO)

G protein-coupled receptor signaling pathway (IEA)

negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning (ISO)

signal transduction (IEA)

Cellular Component

ciliary membrane (IEA)

cilium (ISO)

membrane (IEA)

recycling endosome (IBA,ISO)

Molecular Function

G protein-coupled receptor activity (IBA,IEA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:23332756	PMID:28154160

Genomics

Comparative Map Data

Gpr161
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	80,111,271 - 80,156,517 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	80,117,114 - 80,152,861 (+)	Ensembl				GRCr8
mRatBN7.2	13	77,578,257 - 77,623,661 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	77,577,739 - 77,619,613 (+)	Ensembl				mRatBN7.2
Rnor_6.0	13	83,530,389 - 83,576,117 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	83,531,018 - 83,571,505 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	88,409,782 - 88,455,575 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	81,053,624 - 81,074,896 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	77,290,655 - 77,336,787 (+)	NCBI		Celera
Cytogenetic Map	13	q23	NCBI

GPR161
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	168,079,542 - 168,137,667 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	168,079,542 - 168,137,685 (-)	Ensembl			hg38	GRCh38
GRCh37	1	168,048,780 - 168,106,905 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	166,320,621 - 166,372,248 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	141,162,980 - 141,214,616 (-)	NCBI		Celera
Cytogenetic Map	1	q24.2	NCBI
HuRef	1	139,293,385 - 139,351,133 (-)	NCBI		HuRef
CHM1_1	1	169,470,990 - 169,529,180 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	167,431,007 - 167,489,154 (-)	NCBI		T2T-CHM13v2.0

Gpr161
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	165,108,760 - 165,154,314 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	165,123,358 - 165,154,314 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	165,281,184 - 165,326,747 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	165,295,789 - 165,326,745 (+)	Ensembl			mm10	GRCm38
MGSCv37	1	167,225,897 - 167,251,982 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	167,132,441 - 167,161,079 (+)	NCBI		MGSCv36	mm8
Celera	1	167,740,027 - 167,766,443 (+)	NCBI		Celera
Cytogenetic Map	1	H2.2	NCBI
cM Map	1	72.64	NCBI

Gpr161
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955462	8,981,157 - 9,028,946 (+)	Ensembl
ChiLan1.0	NW_004955462	8,981,729 - 9,034,009 (+)	NCBI	ChiLan1.0	ChiLan1.0

GPR161
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	81,627,443 - 81,685,495 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	81,295,579 - 81,354,170 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	143,566,775 - 143,625,357 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	147,293,355 - 147,351,510 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	147,299,350 - 147,350,451 (-)	Ensembl			panPan2	panpan1.1

GPR161
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	30,364,999 - 30,411,038 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	30,366,068 - 30,407,268 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	29,895,733 - 29,948,158 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	30,176,808 - 30,229,264 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	30,182,446 - 30,224,803 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	30,016,737 - 30,069,149 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	30,047,700 - 30,100,163 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	30,285,703 - 30,338,184 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Gpr161
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	100,250,949 - 100,284,605 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936481	18,097,692 - 18,129,873 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936481	18,097,704 - 18,130,023 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPR161
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	82,844,941 - 82,905,534 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	82,844,944 - 82,909,329 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	90,518,333 - 90,577,014 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GPR161
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	60,908,741 - 60,965,168 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	60,940,047 - 60,959,181 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666055	62,633,696 - 62,690,375 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gpr161
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624826	6,089,127 - 6,134,127 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624826	6,089,127 - 6,135,076 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Gpr161
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	44,427,179 - 44,468,895 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Gpr161
208 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	58
Count of miRNA genes:	55
Interacting mature miRNAs:	57
Transcripts:	ENSRNOT00000004104
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	48639634	93639634	Rat
10755495	Bp387	Blood pressure QTL 387	3.78		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37216241	90057603	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	38975045	103588154	Rat
8655951	Rf63	Renal function QTL 63	12.2		blood urea nitrogen amount (VT:0005265)	plasma urea nitrogen level (CMO:0000586)	13	71610804	109350286	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
8655945	Rf61	Renal function QTL 61	3.6		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	13	71610804	89333251	Rat
71119	Thym2	Thymus enlargement QTL 2	3.8		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	13	48749814	87285480	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	39968211	83286298	Rat
1331783	Bp221	Blood pressure QTL 221	3.72886		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	71610804	89333251	Rat
8655959	Pur32	Proteinuria QTL 32	8.4		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	72984506	99745408	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	67635937	109350286	Rat
1300166	Kidm6	Kidney mass QTL 6	3.93		kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	13	71610804	89333251	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	7421791	87286911	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	37087983	82087983	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	40983585	85983585	Rat
724564	Uae11	Urinary albumin excretion QTL 11	5.7		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	13	47354258	94285672	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
738027	Lnnr6	Liver neoplastic nodule remodeling QTL 6	3.3		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	65613454	109350286	Rat
7387280	Uae43	Urinary albumin excretion QTL 43	5.69	0.4174	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	68983334	109350286	Rat
738026	Lnnr5	Liver neoplastic nodule remodeling QTL 5	3.29		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	62424592	88113509	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	67635937	109350286	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	39924693	84924693	Rat
1576318	Schws5	Schwannoma susceptibility QTL 5		0.0351	nervous system integrity trait (VT:0010566)	post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)	13	64497900	109350286	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	6002008	88706694	Rat
12879477	Bp401	Blood pressure QTL 401			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	39814726	84814726	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	39968211	84968211	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	64375743	109350286	Rat
11530006	Niddm72	Non-insulin dependent diabetes mellitus QTL 72		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	38286298	83286298	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	67635937	109350286	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	160	90	89	58	87	58	6	350	187	11	139	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_001075481	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006221526	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006250191	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762684	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008762696	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769710	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769712	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598995	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604645	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272753	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063272754	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000004104 ⟹ ENSRNOP00000004104

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	80,117,114 - 80,152,861 (+)	Ensembl
mRatBN7.2 Ensembl	13	77,577,739 - 77,619,613 (+)	Ensembl
Rnor_6.0 Ensembl	13	83,531,018 - 83,571,505 (+)	Ensembl

RefSeq Acc Id:

XM_017598995 ⟹ XP_017454484

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	80,111,776 - 80,156,517 (+)	NCBI
mRatBN7.2	13	77,578,719 - 77,623,661 (+)	NCBI
Rnor_6.0	13	83,530,389 - 83,576,117 (+)	NCBI

Sequence:

show sequence

TTACATCCACTTTCCATTCTTTAGGGTCTACCTTCGGGGTTATTTGCCGTGGTACTGCCAGTGT
CCTGGACCGCGTCTGCCACTAGACAGATGCCCTCAGTGGTTGGTTGGATGAACGAAAGGGAAGG
GAGAGCATCAGTTCGTGCCCTGGACTCAGTCGAGGAGGGCCGCGCCCCCTGCGGCCCGCTCAGG
AATGAGGGTATGGAACGCAGCAGCTAAGACTCTCGGCTGGAATCCGTGAGGACCAGTGGTCCCA
GCATGCTCTGCTCACCGCATCCCGAGGCGCACTGACCATGAGCCTCAACTCCTCCCTCAGCTAC
AGGAAGGAGCTGAGCAACCTCACTGCCGCAGAGGGTGGCGAAGGGGGCGCTGTCTCCGAGTTCA
TCGCCATCATCATCATCACTGTCCTCGTCTGCCTGGGCAACCTGGTCATCGTGGTCACCTTGTA
CAAGAAATCCTACCTTCTCACCCTCAGCAACAAGTTCGTCTTCAGTCTGACCCTGTCCAACTTC
CTGTTGTCCGTGCTGGTGCTGCCGTTCGTGGTGACCAGCTCCATACGGAGGGAATGGATCTTCG
GTGTGGTCTGGTGCAACTTCTCTGCCCTTCTCTACCTGCTGATCAGCTCGGCCAGCATGCTGAC
CCTTGGCGTTATTGCCATCGATCGCTATTACGCTGTCCTGTACCCAATGGTGTACCCCATGAAG
ATCACAGGGAACCGAGCTGTGATGGCTCTTGTCTACATCTGGCTTCACTCTCTCATTGGCTGTC
TGCCACCCCTCTTTGGCTGGTCATCGGTGGAGTTCGATGAGTTCAAGTGGATGTGTGTGGCCGC
GTGGCACCGGGAACCTGGCTACACCGTTTTCTGGCAGATCTGGTGTGCCCTGTTCCCCTTCCTC
ATCATGCTAGTCTGCTATGGTTTCATCTTCCGGGTAGCCAGGGTCAAGGCCCGAAAGGTGCACT
GTGGCACGGTGGTCACTGTGGAGGAAGACGCCCAGAGGAGTGGGAGGAAGAATTCTAGTACCTC
CACTTCCTCCTCTGGCAGTAGGAGGAATGCCCTTCAGGGAGTGGTCTATTCCGCTAACCAGTGC
AAAGCCCTCATCACCATCCTGGTGGTCATTGGCGCTTTCATGGTCACCTGGGGCCCCTACATGG
TTGTCATTACCTCAGAGGCACTCTGGGGGAAGAACTATGTCTCGCCAACCCTGGAGACTTGGGC
CACGTGGCTGTCCTTTACCAGTGCTATCTGCCATCCTCTGATCTACGGACTCTGGAACAAGACT
GTTCGCAAGGAGCTCCTGGGCATGTGCTTTGGGGACCGTTACTACCGGGAGTCATTTGTGCAGC
GACAGAGGACCTCCAGGCTCTTCAGCATTTCCAACAGGATCACAGACCTGGGTCTGTCCCCACA
CCTCACGGCACTCATGGCAGGCGGACAGTCCCTGGGACACAGCAGCAGCACTGGTGACACAGGC
TTCAGCTACTCTCAGGATTCAGGGACAGATGTGATGCTACTGGAAGACGGTGCTTCTGATGACA
GCCCTCCCCAGCACTGCACTTGCCCGCCCAAGAGGAGGAGCTCCGTGACATTTGAGGACGAAGT
GGAACAGATCAAAGAGGCTGCCAAGAACTCTATTCTTCATGTGAAAGCTGAAGTACACAAATCC
TTGGACAGTTATGCAGCCAGCTTGGCTAAAGCCATTGAGGCTGAAGCCAAAATCAACTTATTTG
GGGAGGAGGCTCTGCCAGGGGTCTTGTTCACAGCACGGACAGTCCCGGGGGCGAGCTTTGGGGG
CCGTCGAGGCAGCAGGACTCTTGTGAATCAGAGGCTGCAGCTACAGAGCATCAAGGAAGGGAAT
GTCTTAGCTGCAGAACAGAGTTGAAGGCTCTGAGGGGACTGGGGCTGCAGTGGAGGAGCTACTG
GTACTGGTGCCTGTGCCAAGACCCTGGAACATGTCACCACGCAGAGAGGGCCCAGATGCCGGGA
AGGAAACATCTGGTACGCAGCCAGGAGGATCGAAAGTACTGTCTCTAGTCTCTGATGTCAGCTG
TCTGCTGTAAAGGCATACGTGGGCTGCTTCAGGGCTCCTGGGATGGAACGAGGCTTCCCAAGCA
TACGTTAGAAGCAGATGGAGATGTGGCCGGGGTTTCAGGAAGACTAGAGACAGTGGATGTGAAA
GGGAAGCCACCATGAGGATCTTGTCTTCATCAGTATCCAGCTGGTCTAGCGGCCCCTGGTCTCA
GTGAGGCCTCTGAGGCAATCCCTACTCAGTGCACCTCCTGGGGACAGCACAGCTCTCCTTAGTA
CTGTTAGACCACCTAGGGGCTCTGTGTGGTTGATCCAGACATTGTGGGGCCACATGTGCTAGAT
TAAATGCAAAAACAGTCCCGAGAGCACTCAGGAGTAGAGTACCCTACATAGACATCCCATATCT
ACTGCCCTAGTTAGGACTTGGCCTTTGGTGGCACCTGCTGCTGGCCTATAGAAACAGCCCAAAG
GCCACCCAAGATGTGGCCACCCCACCCCCTTCCTTGTTGACAGATTTTTATTAATATTATTATT
TGAAAAGACAGGAGAAACCACTATAAAAGACAAGGGTGAGTACCAGGCGTTTCATTTCCAGAAT
AATAAAACCTGGAGATTAGGGCATATCACGAAGACTGGGACTGTGAGGTCATGCACAGCTGGGG
AGAATTTGAGGGGAAATCCCTCACACAGGAGATATGGGAGATGCTTGAGCAACTGGCAGACATA
GTTGGCCTCACTTTCCAGAGGCAGTTGTGACTGTCATTGCAAGTTTGGGGCTGGCACAAGGTAG
AAAGGGCACTGGACCTGAGTTCATAGCCTGGGTTCTTGACCCAGCTTGGTTTTTGTCTGCATGT
TGTCTAGGACATTCTGTCCTATCACTAGGCCATTTGGAGAAAAGAAAGGTGTGAGGAGTTGGAA
CAAGTTGCCTCCAAGACAATTCCAGCTCTGATCTTTGATGTCTTCTGAATCTGTAAGAGATGGG
GACAAACTGAGCATGACTGGAGGGAGACCCAGCGTCTGCATACTGTTGAGGGCGTGCCCAGTGA
GCACAGGGAGAGCCACCTTCGTGCTGTGGCCCTGGTGTCTGCACTGCTTGGCTGTTTAGGGAGA
TCCTAAATGCTGACTACTGAGACGCGGGTACTGAAAACCTTCCATAGGCTTGGCTTGCACCTTT
GGGTGCTTGATTCTGTTACCTACTCCAGGTCAGCTGTGCAGGGGAATGGCAGGATTTTGGATGG
AGTGACAGGACAGGACCTGCTCTCCTGGCAGCACCTGTCCTCTCTGTATTCTGTTCTGCTTTTC
TAGTACTTGTCTGGTGTCTGGAGGGACCCTATTCCCAATTACCCAGTAAGCACTGAAGTGGAGC
ATGCCCCCTAAGTACAGGTCGTCAGTGCAAAGGATAGAGAGCTCTTCCCTGATTGCCCAGGGCT
TTAGAAAGGATGCTGAGGCCTCTGAACCCTACTGGCTGACCCCAGAGTCACCAGTATTCAAGAA
GAGAGCTGATCTAGAAAACTGAATTCCACTCCCACCCCTTTTAAAGAAGCGAGGCCTACTCATC
TGCCTAACACTGCAGAACTGTCAGCACATCAGTCACCGAGCACTGGGGGAGAAACACTGGTGTT
TACCAGAGCAGAGGGCAGGAGTCCTGATGCTGATGCTGTTGGGGATGCAGAGCATCAGGCAGTG
ATAATGGCACTGTGGCTACTCAGGGTCTGAGTACTCCAGCTAGGGTGCTAGGGTTGAGCCATTG
GGCGACCATCTGGGACACGTCTTGGGAGGTTTTTAGGATCCAGAACCATGGTTTTACATATTCA
GGCATTCTGATTTGCCCAACAGAGCTAGAGAGAAGCAGGCTGGAAAGAGAGGGAGAGGTAGTTC
CATATAGGCTCTTTTGTCCTCTTTGGAGGACACCCGTGTTTTGTGCAGATGTCCACCGTCCCAA
TTAAACCCTGCCATGTAATGGCAAAATCTGCTGCAAATTACTGTGCAGTGGCAGGCCTGAGGCC
TTCCCCAGGGGAACCACAGGTAGTGTAGGTGGGACGTTTGGCCACTTGTTTTGCTTAAATACCT
CAGTCTTTCTGATTCTGACAGGATCACTTGTAGGGCCATGGCCCGTCTCCGCTGCTTCTTTACC
AAGATTTTACCCTCATCTTGGTTCCTGTGCTGTGTTTGATGCCAGCTGAGTGACCTGCTGCATC
CCAGAAGGCACTAGGTCCGGCACTGCAGTGTACACAGCTCAGCACCTCCTTTTCCCTGGCCAGA
CAACTCAAGTTAGAGTTTAAGACCTTAGGCATTAGCATGGCAGCAGCATGGCTGTGGAAAGGAC
AAAACAAAGACCAAACCAACCAACCAGTCAAACAAAACATGGTGGTTTGTTCCTCTGAGCCCTG
GTCTCTAACCTTATAGCTGATCCTTACCTTCTATGTGTGACCCCCTGTTGGAGTTCACTGGAAC
TACCTGTACTGAGCTGTGTGATCTTAAACAAGTCACTGCTCCTGGGTCAGGCAGGGGGAAGGAT
TGTAAAGACCACGGCCCGTTGGTGCTAATGTTCGTAGATTCTCATTTGTATAACGGACTCCATC
TTTCAGCCAAGAATTAAACCATCACCACCAAGACAAACTCGGTATTATCAGCAGAGCACTGTAG
TTTGGGTTTAGACAAGAGGAGAACAGTGTGGACACAGCGAGAGAGCTTGCTGGTCTGTTGAGAT
AGGAACCATGCCTGCTTTTTCAAATGGACAGTGTGCTCCTTAGACTTGCAGGCTAGAGAGACAT
TTCTCAGTGGATCCTAAGATGAACTCAGGAAACCTGTCCAGCCTCATTTCATCTGTCTCCTGCC
TGTCTGCAAGGAATGAGGATGATGTGGTTAAACATGAGGCAGCCAAGGACAGGCATGTATCAGG
TCCCACTGTGTGCCTCACTTAAAACAGCTAAGAGCCTATGAGGTGCTGGGCACTATTGAAGACT
TCAAACGCACCATCTCCCTTTGCTTCGGGCAGAAGGGATAGAGTCGGGATGGTGCTGGTGTGTG
ATGGCTGTGGGTTAAGATTTCAGGTTGCCAACTACTAGCTAAGTGTTTGGGGGCAAATTACTCA
GTATTCTTGCATCTGTAAAATGAAGTTTTGCAATCTATTTACACCTAGGGACACAGAATCCAAA
GATACTGCCTGCATAGGGTGCTTGGTAGACTACAGAAATGCTCGTGGGGCGTCCAGCACAGGAC
GTAGGTGCAGGGAAACCTGAGCCACTGGTCTTGCTTCTCAGTGTAACTGATGGGGCAGACTCCT
TCCTGTTTTACAGGGATCTCTAATGCCAAGAACTTTCAAAAGACATGCTGCCCAATCCAGGGTA
ATTAATTATGTTGAGAGTTGCTGCCTGCAGACTTGTTATTCAGTACAACAGGACTTAATGGAGA
TGAAGGACTGCTGACAAGAGGCAGGCCATAGTGGAGAAGCGGAGTGGGATGTGGGGTGCAGGAG
GTTAGTAGGAACAGAAATGGGCTTCTCTAGTAGGAAAGTCTTCTTTCCACATCAGTGGCCTGAC
TACACAAAAAAGAAAAATTTCTACGTTACCCCGAATTAAAGATGAGTATATACTGTGGAGTATA
TTTCCAATGTTGACCTTCCTTATACCAGAAAGAACATCCCACCCCACCCCAATGCCTTTAGGTG
CTGAGAACTGCTCTGTCTGGCAGGGACAGTGTCTGGTTCCCGGTTCCCAGAGCTCTTGTCTTCC
ATGACCCTGGTGGAAGATGTAGGGGCGGCATAGGTGTCCATCCGTGTCCCAGACTGTACAGAAC
CAGAGGAAGCCTGGGGATGAAGAGGGATCATGGATGTTGCCAGTCATAGATGGCTACAAGGAGG
GACAGGTGGGCACTGTGGGGTGGGGAGAGAAACAATGAGAATCCAGAAAGGCCATAGAAAAGCC
ATGTCCCAAAATGAAGTCAGGCCAAATCACTAGGTCTTGGTCATGAGGCTGAGAAGATCAAGCC
TGTAGCCAGAGGAGAATGAGGCACAGATGGGTTAAAAAAAAGTCCCAATGTCAGGGGATCATCT
ATTGGAAAGAATTCAAAGCACAAACACTGATCTGCACAAGATTACCACAAGCACAATCTTGGTC
AATGTAAACTGCGTTTATTTAAAAATGAATTTGTACCAGCTCTGAAAAAAAAAAGAACTAAAAC
AGAAATGAATTTGTAAAAGCAGTATTAATGGCTTAGGAGTCAGTGGCCACTTCTGGTTTTCCTT
TTGACACTATCTGAAACACAAAAAATCACAGTTGAGCTAGTTCCTTCCAAAGGAAAGGGCAGTC
CCAGAGAAGTTGGGTGACACGACCATGCCAAGTGTAGTAGCCTGTATGCCTAGAAATGGATCTG
CTGGTGGGCTAGACATGCCCCAAAGTGTCCTTCCTGTGTGCTGTTCTGATGACGTATACCTGAA
GGAAGACATGGTTAAAAACTAAACTTCAAAAATAAATAAAAACCCAACCTAATCCTGCAGTATA
TTTAACTTGAAGTTTTGGATGGTGTTTTTGAAGATAAAATTGTGTGGGTTATTATATGTAAATC
AGTATTTATGAATAAGTAAAAGTGTATGTAGACTAGTTTTGTTTACCTGGTTAAATGTTTTTGG
GATGTGTTTATCTGTGTAAATTGTCAGTTTGCA

hide sequence

RefSeq Acc Id:

XM_063272753 ⟹ XP_063128823

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	80,111,271 - 80,156,517 (+)	NCBI

RefSeq Acc Id:

XM_063272754 ⟹ XP_063128824

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	80,111,776 - 80,156,517 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_017454484	(Get FASTA)	NCBI Sequence Viewer
	XP_063128823	(Get FASTA)	NCBI Sequence Viewer
	XP_063128824	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDM09330	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000004104
	ENSRNOP00000004104.6

RefSeq Acc Id:

XP_017454484 ⟸ XM_017598995

- UniProtKB:

F1M5Q2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSLNSSLSYRKELSNLTAAEGGEGGAVSEFIAIIIITVLVCLGNLVIVVTLYKKSYLLTLSNKF
VFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAV
LYPMVYPMKITGNRAVMALVYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHREPGYTVFWQ
IWCALFPFLIMLVCYGFIFRVARVKARKVHCGTVVTVEEDAQRSGRKNSSTSTSSSGSRRNALQ
GVVYSANQCKALITILVVIGAFMVTWGPYMVVITSEALWGKNYVSPTLETWATWLSFTSAICHP
LIYGLWNKTVRKELLGMCFGDRYYRESFVQRQRTSRLFSISNRITDLGLSPHLTALMAGGQSLG
HSSSTGDTGFSYSQDSGTDVMLLEDGASDDSPPQHCTCPPKRRSSVTFEDEVEQIKEAAKNSIL
HVKAEVHKSLDSYAASLAKAIEAEAKINLFGEEALPGVLFTARTVPGASFGGRRGSRTLVNQRL
QLQSIKEGNVLAAEQS

hide sequence

Ensembl Acc Id:

ENSRNOP00000004104 ⟸ ENSRNOT00000004104

RefSeq Acc Id:	XP_063128823 ⟸ XM_063272753
- UniProtKB:	F1M5Q2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063128824 ⟸ XM_063272754
- UniProtKB:	F1M5Q2 (UniProtKB/TrEMBL)

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M5Q2-F1-model_v2	AlphaFold	F1M5Q2	1-528	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563245	AgrOrtholog
BioCyc Gene	G2FUF-17570	BioCyc
Ensembl Genes	ENSRNOG00000003073	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000004104	ENTREZGENE
	ENSRNOT00000004104.8	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/TrEMBL
KEGG Report	rno:289180	UniProtKB/TrEMBL
NCBI Gene	289180	ENTREZGENE
PANTHER	G PROTEIN-COUPLED RECEPTOR	UniProtKB/TrEMBL
	G-PROTEIN COUPLED RECEPTOR 161	UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/TrEMBL
PhenoGen	Gpr161	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000003073	RatGTEx
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/TrEMBL
UniProt	F1M5Q2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2010-05-05	Gpr161	G protein-coupled receptor 161	RGD1563245	similar to G protein-coupled receptor 161	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1563245	similar to G protein-coupled receptor 161	RGD1563245_predicted	similar to G protein-coupled receptor 161 (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1563245_predicted	similar to G protein-coupled receptor 161 (predicted)	LOC289180	similar to G protein-coupled receptor 161	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC289180	similar to G protein-coupled receptor 161			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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