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Gene: Dus3l (dihydrouridine synthase 3-like) Rattus norvegicus

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Symbol:

Dus3l

Name:

dihydrouridine synthase 3-like

RGD ID:

1563228

Description:

Predicted to enable mRNA dihydrouridine synthase activity and tRNA-dihydrouridine47 synthase activity. Predicted to be involved in regulation of translation and tRNA dihydrouridine synthesis. Orthologous to human DUS3L (dihydrouridine synthase 3 like); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acrylamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

dihydrouridine synthase 3-like (S. cerevisiae); MGC124806; mRNA-dihydrouridine synthase DUS3L; similar to putative zinc finger protein; tRNA-dihydrouridine synthase 3-like; tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DUS3L (dihydrouridine synthase 3 like)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Dus3l (dihydrouridine synthase 3 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dus3l (dihydrouridine synthase 3 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DUS3L (dihydrouridine synthase 3 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DUS3L (dihydrouridine synthase 3 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dus3l (dihydrouridine synthase 3 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DUS3L (dihydrouridine synthase 3 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DUS3L (dihydrouridine synthase 3 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dus3l (dihydrouridine synthase 3 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Dus3l (dihydrouridine synthase 3 like)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	DUS3L (dihydrouridine synthase 3 like)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Dus3l (dihydrouridine synthase 3 like)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	dus3l (dihydrouridine synthase 3-like (S. cerevisiae))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG10463	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	DUS3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y37E11B.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	dus3l	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	1,680,619 - 1,685,784 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	1,675,819 - 1,686,367 (+)	Ensembl				GRCr8
mRatBN7.2	9	1,593,491 - 1,598,663 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	1,594,123 - 1,598,655 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	2,028,265 - 2,032,806 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	7,377,380 - 7,381,917 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	6,333,460 - 6,338,001 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	10,289,440 - 10,294,213 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	10,289,446 - 10,293,980 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	9,286,520 - 9,291,291 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	9	6,918,090 - 6,922,626 (-)	NCBI		Celera
Cytogenetic Map	9	q11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

2-palmitoylglycerol (ISO)

acrylamide (EXP)

antirheumatic drug (ISO)

beta-naphthoflavone (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (EXP)

caffeine (ISO)

choline (ISO)

clothianidin (ISO)

coumarin (ISO)

cyclosporin A (ISO)

DDE (ISO)

decabromodiphenyl ether (EXP)

diethyl maleate (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

folic acid (ISO)

FR900359 (ISO)

L-methionine (ISO)

nitrates (ISO)

paracetamol (EXP,ISO)

perfluorononanoic acid (ISO)

progesterone (ISO)

rotenone (ISO)

sodium arsenite (ISO)

Soman (EXP)

tamoxifen (ISO)

tetrachloroethene (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

mRNA processing (IEA)

regulation of translation (ISO,ISS)

tRNA dihydrouridine synthesis (IEA,ISO,ISS)

tRNA processing (IEA)

Molecular Function

flavin adenine dinucleotide binding (IEA)

metal ion binding (IEA)

mRNA dihydrouridine synthase activity (IEA,ISO)

oxidoreductase activity (IEA)

protein binding (ISO)

tRNA dihydrouridine synthase activity (IBA,IEA)

tRNA-dihydrouridine47 synthase activity (IEA,ISO,ISS)

zinc ion binding (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334	PMID:22681889

Genomics

Comparative Map Data

Dus3l
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	9	1,680,619 - 1,685,784 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	9	1,675,819 - 1,686,367 (+)	Ensembl				GRCr8
mRatBN7.2	9	1,593,491 - 1,598,663 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	1,594,123 - 1,598,655 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	9	2,028,265 - 2,032,806 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	9	7,377,380 - 7,381,917 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	9	6,333,460 - 6,338,001 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	9	10,289,440 - 10,294,213 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	10,289,446 - 10,293,980 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	9	9,286,520 - 9,291,291 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	9	6,918,090 - 6,922,626 (-)	NCBI		Celera
Cytogenetic Map	9	q11	NCBI

DUS3L
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	5,785,140 - 5,791,163 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	5,784,832 - 5,791,225 (-)	Ensembl			hg38	GRCh38
GRCh37	19	5,785,151 - 5,791,174 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	5,736,151 - 5,742,192 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	19	5,723,144 - 5,730,021 (-)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	5,546,085 - 5,552,589 (-)	NCBI		HuRef
CHM1_1	19	5,785,079 - 5,791,308 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	5,771,937 - 5,778,591 (-)	NCBI		T2T-CHM13v2.0

Dus3l
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	57,069,224 - 57,077,093 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	57,071,757 - 57,077,093 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	17	56,764,751 - 56,770,093 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	56,764,757 - 56,770,093 (+)	Ensembl			mm10	GRCm38
MGSCv37	17	56,904,174 - 56,909,516 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	17	56,449,902 - 56,454,965 (+)	NCBI		MGSCv36	mm8
Celera	17	61,108,892 - 61,114,234 (+)	NCBI		Celera
Cytogenetic Map	17	D	NCBI
cM Map	17	29.5	NCBI

Dus3l
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	3,653,257 - 3,660,331 (+)	Ensembl
ChiLan1.0	NW_004955495	3,653,613 - 3,660,331 (+)	NCBI	ChiLan1.0	ChiLan1.0

DUS3L
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	10,179,205 - 10,186,888 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	9,403,225 - 9,413,083 (-)	NCBI		NHGRI_mPanPan1
PanPan1.1 Ensembl	19	5,731,457 - 5,737,775 (-)	Ensembl			panPan2	panpan1.1

DUS3L
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	54,250,369 - 54,255,981 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	54,250,871 - 54,255,995 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	53,977,808 - 53,983,421 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	54,902,723 - 54,908,336 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	54,903,204 - 54,908,350 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	53,969,030 - 53,974,635 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	54,449,603 - 54,455,181 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	54,646,813 - 54,652,426 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Dus3l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	214,497,957 - 214,502,948 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	3,331,904 - 3,337,277 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	3,331,563 - 3,337,276 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DUS3L
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	73,197,669 - 73,204,977 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	2	73,197,614 - 73,202,676 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	73,719,549 - 73,724,598 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DUS3L
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	5,430,558 - 5,437,638 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	5,430,580 - 5,437,452 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666081	2,627,456 - 2,630,452 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dus3l
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	4,431,167 - 4,437,365 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624828	4,431,172 - 4,437,459 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Dus3l
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	4	88,136,212 - 88,140,889 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Dus3l
27 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	35
Count of miRNA genes:	35
Interacting mature miRNAs:	35
Transcripts:	ENSRNOT00000072703
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
631533	Iresp3	Immunoglobin response QTL3	16.2		blood immunoglobulin E amount (VT:0002492)	serum immunoglobulin E level (CMO:0002101)	9	1	6094576	Rat
10054141	Gmadr4	Adrenal mass QTL 4	2.45	0.0074	adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	9	1	21707400	Rat
9589158	Gluco65	Glucose level QTL 65	6.82	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	9	496645	45496645	Rat
7411592	Foco8	Food consumption QTL 8	7.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	496645	45496645	Rat
7207814	Bmd91	Bone mineral density QTL 91	3.5		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	9	1	31250552	Rat
9589055	Scfw5	Subcutaneous fat weight QTL 5	5.55	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	9	496645	45496645	Rat
1300124	Cm4	Cardiac mass QTL 4	3.55		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	9	1	41763315	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001034923	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006244314	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC105780	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474092	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000072703 ⟹ ENSRNOP00000066698

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	1,675,819 - 1,685,788 (+)	Ensembl
mRatBN7.2 Ensembl	9	1,594,123 - 1,598,655 (+)	Ensembl
Rnor_6.0 Ensembl	9	10,289,446 - 10,293,980 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000115667 ⟹ ENSRNOP00000095494

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	1,681,740 - 1,685,780 (+)	Ensembl
mRatBN7.2 Ensembl	9	1,594,626 - 1,598,655 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000137549 ⟹ ENSRNOP00000098746

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	1,681,157 - 1,686,367 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000137966 ⟹ ENSRNOP00000104240

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	1,681,157 - 1,685,788 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000152627 ⟹ ENSRNOP00000099567

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	9	1,681,157 - 1,685,788 (+)	Ensembl

RefSeq Acc Id:

NM_001034923 ⟹ NP_001030095

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	1,681,248 - 1,685,784 (+)	NCBI
mRatBN7.2	9	1,594,123 - 1,598,659 (+)	NCBI
Rnor_6.0	9	10,289,444 - 10,293,980 (-)	NCBI
Rnor_5.0	9	9,286,520 - 9,291,291 (-)	NCBI
Celera	9	6,918,090 - 6,922,626 (-)	RGD

Sequence:

show sequence

CCGGAAGACTTTCCTGCCACACTCCAGAGCCAGTGCGAGGGGCGTCGATGGCGGAGGTTGCGGA
GGTAGCAGCTGAGAGCGGTGGTGGCGGTGACTCCGGAGTTGGCGCGTGCGAACGGGGGGTGGCG
CCCATTAAAGCTCAGTACCGCACCACCAAAGAAAGGTTCCACGAATACCTGGATGCAGACAAGC
AGGAGGGTGCGTGCCAGGAAACGCCTACAGAGGGCCCAGCTGAACCGGAGGCCAAAAGAATCCG
CTTGGAAGATGGGCAGGAGAATGGGAAGACAGAGGTGGCAGTTGAGTCCCATGAAAGGCAGGTG
CCCAAGAGGGCCCGGGGCCAAAACAAAAGCCGGCCCCACATGAAGCCAGCACACTATGACAAGG
AGAGGCTCTGCCCATCCCTCCTTCAGGAGTCGGCCACTCCATGTGCATTTGGAGACCGTTGCCG
CTTCCTGCATGATGTGGGGCGCTACCTGGAGACCAAACCAGCAGACCTGGGCCCCCACTGCGTG
CTCTTCAACACCTTCGGCCGGTGCCCTTACAGCATGACCTGTCGTTTTGCTGGGGCACACTTGG
GACCTGAGGGTCAGAACCTGGTGCAGGAGGAGGTGGTGGCCCGCTGTGCACAGCTCCCTTCGGT
GCGAAATGGCCTCGACAGGGCTCTGCAGCAGCAGCTGCGGAAGCGCCAAGTTTGCTTTGAGCGA
GCTGAGCAGGCCCTGAGCCACCTTACCCAGGGCCCCATGCCCACGATTGCCCCTGAGAGCACTG
TGGCCACATTGACCCCAAAGCACAGCAGCTGCCATGTCCAGCTAGACAACGTAGGAGGGGACGG
TGCCAGGCAGGGCAGCCCTGTGCCCACCTGCGGCCCCTTGACCGACGAGGATGTGGTCCGGCTG
CGGCCCTGTGAGAAGAAGCGGCTAGACATCAGCGGAAAGCTGTACCTGGCTCCTTTAACCACGT
GTGGAAACCTACCCTTTCGCCGTATCTGCAAGCGCTTCGGTGCAGATGTGACCTGCGGTGAGAT
GGCCATGTGCACAAACCTGCTCCAGGGACAGATGTCTGAGTGGGCTTTGCTCAAGCGCCACCCC
TGCGAGGACATCTTCGGGGTTCAGCTGGAGGGCGCATTCCCTGACACCATGACCAAGTGTGCTG
AGCTGCTCAACCGCACGATTGACGTGGACTTCGTGGACATCAACGTGGGCTGCCCTATCGACCT
CGTCTATAAGAAGGGTGGTGGCTGTGCACTCATGAATCGCTCAGCCAAGTTCCAACAGATTGTG
CGGGGCATGAATGAGGTGTTGGATGTACCCTTGACGGTGAAGATGCGCACGGGTGTTCAGGAGC
GTGTGAGCCTGGCACACCGACTGCTGCCTGAACTGCGGAACTGGGGTGTTGCACTGGTCACACT
CCATGGCCGCTCCAGGGAACAGCGCTACACCAGGCTGGCCGACTGGCCCTACATCGAACAGTGT
GCCAAGGTGGCCAGCCCCATGCCCCTGTTTGGAAATGGAGACATCCTTTCGTTTGAGGACGCCA
ACTGTGCCATGCAGACAGGGGTTGCTGGGATCATGGTTGCCCGTGGCGCCTTGCTCAAGCCCTG
GCTGTTCACTGAGATCAAAGAACAGAGACACTGGGACATCTCATCCTCTGAGCGCCTGGACATC
TTGAGAGACTTCACACACTATGGCCTGGAACACTGGGGCTCTGACACACAGGGTGTGGAACGGA
CCCGGCGCTTCCTTCTTGAGTGGCTCTCCTTTCTTTGCAGGTATGTGCCCGTGGGCCTGCTGGA
ACGACTGCCACAGAGGATCAATGAAAGGCCACCCTACTACTTAGGCCGTGACTACCTGGAGACA
CTCATGGCCAGCCAGCAGGCTGCAGACTGGATTCGAATCAGTGAGATGCTGCTTGGACCAGTTC
CACCTGGCTTCGTCTTCCTGCCCAAGCACAAAGCCAATGCCTACAAGTAGCTAACAGAGACAAT
AAATTTTATTCTTGTAGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006244314 ⟹ XP_006244376

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	9	1,680,619 - 1,685,784 (+)	NCBI
mRatBN7.2	9	1,593,491 - 1,598,663 (+)	NCBI
Rnor_6.0	9	10,289,440 - 10,294,213 (-)	NCBI
Rnor_5.0	9	9,286,520 - 9,291,291 (-)	NCBI

Sequence:

show sequence

CGGTCAGTGTGAGCTGCATTCCCCTTCCCCAACACGAACTCACTTCTACTAGGCAACAGTGACC
CACGGGGGACCGACGTGAACCCCGTGGGAACCCCGCCGGGACTCTTGAGCACTTCCGGTTCCTG
AGCGGCCCACCCCCACATCCAGACGGCCTTGCGCACGCGCGCCTTAGTATTATTGGTGTGGTCT
GAGCGTGCGCCTTTCTGTAGGCTCCAGAAGACACGGGCGACCCGGAAGACTTTCCTGCCACACT
CCAGAGCCAGTGCGAGGGGCGTCGATGGCGGAGGTTGCGGAGGTACCGCACCACCAAAGAAAGG
TTCCACGAATACCTGGATGCAGACAAGCAGGAGGGTGCGTGCCAGGAAACGCCTACAGAGGGCC
CAGCTGAACCGGAGGCCAAAAGAATCCGCTTGGAAGATGGGCAGGAGAATGGGAAGACAGAGGT
GGCAGTTGAGTCCCATGAAAGGCAGGTGCCCAAGAGGGCCCGGGGCCAAAACAAAAGCCGGCCC
CACATGAAGCCAGCACACTATGACAAGGAGAGGCTCTGCCCATCCCTCCTTCAGGAGTCGGCCA
CTCCATGTGCATTTGGAGACCGTTGCCGCTTCCTGCATGATGTGGGGCGCTACCTGGAGACCAA
ACCAGCAGACCTGGGCCCCCACTGCGTGCTCTTCAACACCTTCGGCCGGTGCCCTTACAGCATG
ACCTGTCGTTTTGCTGGGGCACACTTGGGACCTGAGGGTCAGAACCTGGTGCAGGAGGAGGTGG
TGGCCCGCTGTGCACAGCTCCCTTCGGTGCGAAATGGCCTCGACAGGGCTCTGCAGCAGCAGCT
GCGGAAGCGCCAAGTTTGCTTTGAGCGAGCTGAGCAGGCCCTGAGCCACCTTACCCAGGGCCCC
ATGCCCACGATTGCCCCTGAGAGCACTGTGGCCACATTGACCCCAAAGCACAGCAGCTGCCATG
TCCAGCTAGACAACGTAGGAGGGGACGGTGCCGGGCAGGGCAGCCCTGTGCCCACCTGCGGCCC
CTTGACCGACGAGGATGTGGTCCGGCTGCGGCCCTGTGAGAAGAAGCGGCTAGACATCAGCGGA
AAGCTGTACCTGGCTCCTTTAACCACGTGTGGAAACCTACCCTTTCGCCGTATCTGCAAGCGCT
TCGGTGCAGATGTGACCTGCGGTGAGATGGCCATGTGCACAAACCTGCTCCAGGGACAGATGTC
TGAGTGGGCTTTGCTCAAGCGCCACCCCTGCGAGGACATCTTCGGGGTTCAGCTGGAGGGCGCA
TTCCCTGACACCATGACCAAGTGTGCTGAGCTGCTCAACCGCACGATTGACGTGGACTTCGTGG
ACATCAACGTGGGCTGCCCTATCGACCTCGTCTATAAGAAGGGTGGTGGCTGTGCACTCATGAA
TCGCTCAGCCAAGTTCCAACAGATTGTGCGGGGCATGAATGAGGTGTTGGATGTACCCTTGACG
GTGAAGATGCGCACGGGTGTTCAGGAGCGTGTGAGCCTGGCACACCGACTGCTGCCTGAACTGC
GGAACTGGGGTGTTGCACTGGTCACACTCCATGGCCGCTCCAGGGAACAGCGCTACACCAGGCT
GGCCGACTGGCCCTACATCGAACAGTGTGCCAAGGTGGCCAGCCCCATGCCCCTGTTTGGAAAT
GGAGACATCCTTTCGTTTGAGGACGCCAACTGTGCCATGCAGACAGGGGTTGCTGGGATCATGG
TTGCCCGTGGCGCCTTGCTCAAGCCCTGGCTGTTCACTGAGATCAAAGAACAGAGACACTGGGA
CATCTCATCCTCTGAGCGCCTGGACATCTTGAGAGACTTCACACACTATGGCCTGGAACACTGG
GGCTCTGACACACAGGGTGTGGAACGGACCCGGCGCTTCCTTCTTGAGTGGCTCTCCTTTCTTT
GCAGGTATGTGCCCGTGGGCCTGCTGGAACGACTGCCACAGAGGATCAATGAAAGGCCACCCTA
CTACTTAGGCCGTGACTACCTGGAGACACTCATGGCCAGCCAGCAGGCTGCAGACTGGATTCGA
ATCAGTGAGATGCTGCTTGGACCAGTTCCACCTGGCTTCGTCTTCCTGCCCAAGCACAAAGCCA
ATGCCTACAAGTAGCTAACAGAGACAATAAATTTTATTCTTGTAGAATTTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001030095	(Get FASTA)	NCBI Sequence Viewer
	XP_006244376	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI05781	(Get FASTA)	NCBI Sequence Viewer
	EDL83604	(Get FASTA)	NCBI Sequence Viewer
	EDL83605	(Get FASTA)	NCBI Sequence Viewer
	EDL83606	(Get FASTA)	NCBI Sequence Viewer
	EDL83607	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000066698
GenBank Protein	Q3KRC5	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001030095 ⟸ NM_001034923

- UniProtKB:

Q3KRC5 (UniProtKB/Swiss-Prot), A6KQU6 (UniProtKB/TrEMBL), M0RAY0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAEVAEVAAESGGGGDSGVGACERGVAPIKAQYRTTKERFHEYLDADKQEGACQETPTEGPAEP
EAKRIRLEDGQENGKTEVAVESHERQVPKRARGQNKSRPHMKPAHYDKERLCPSLLQESATPCA
FGDRCRFLHDVGRYLETKPADLGPHCVLFNTFGRCPYSMTCRFAGAHLGPEGQNLVQEEVVARC
AQLPSVRNGLDRALQQQLRKRQVCFERAEQALSHLTQGPMPTIAPESTVATLTPKHSSCHVQLD
NVGGDGARQGSPVPTCGPLTDEDVVRLRPCEKKRLDISGKLYLAPLTTCGNLPFRRICKRFGAD
VTCGEMAMCTNLLQGQMSEWALLKRHPCEDIFGVQLEGAFPDTMTKCAELLNRTIDVDFVDINV
GCPIDLVYKKGGGCALMNRSAKFQQIVRGMNEVLDVPLTVKMRTGVQERVSLAHRLLPELRNWG
VALVTLHGRSREQRYTRLADWPYIEQCAKVASPMPLFGNGDILSFEDANCAMQTGVAGIMVARG
ALLKPWLFTEIKEQRHWDISSSERLDILRDFTHYGLEHWGSDTQGVERTRRFLLEWLSFLCRYV
PVGLLERLPQRINERPPYYLGRDYLETLMASQQAADWIRISEMLLGPVPPGFVFLPKHKANAYK

hide sequence

RefSeq Acc Id:	XP_006244376 ⟸ XM_006244314
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6ALK0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKPAHYDKERLCPSLLQESATPCAFGDRCRFLHDVGRYLETKPADLGPHCVLFNTFGRCPYSMT CRFAGAHLGPEGQNLVQEEVVARCAQLPSVRNGLDRALQQQLRKRQVCFERAEQALSHLTQGPM PTIAPESTVATLTPKHSSCHVQLDNVGGDGAGQGSPVPTCGPLTDEDVVRLRPCEKKRLDISGK LYLAPLTTCGNLPFRRICKRFGADVTCGEMAMCTNLLQGQMSEWALLKRHPCEDIFGVQLEGAF PDTMTKCAELLNRTIDVDFVDINVGCPIDLVYKKGGGCALMNRSAKFQQIVRGMNEVLDVPLTV KMRTGVQERVSLAHRLLPELRNWGVALVTLHGRSREQRYTRLADWPYIEQCAKVASPMPLFGNG DILSFEDANCAMQTGVAGIMVARGALLKPWLFTEIKEQRHWDISSSERLDILRDFTHYGLEHWG SDTQGVERTRRFLLEWLSFLCRYVPVGLLERLPQRINERPPYYLGRDYLETLMASQQAADWIRI SEMLLGPVPPGFVFLPKHKANAYK hide sequence

Ensembl Acc Id:

ENSRNOP00000066698 ⟸ ENSRNOT00000072703

Ensembl Acc Id:

ENSRNOP00000095494 ⟸ ENSRNOT00000115667

Ensembl Acc Id:

ENSRNOP00000099567 ⟸ ENSRNOT00000152627

Ensembl Acc Id:

ENSRNOP00000098746 ⟸ ENSRNOT00000137549

Ensembl Acc Id:

ENSRNOP00000104240 ⟸ ENSRNOT00000137966

Protein Domains

C3H1-type DUS-like FMN-binding

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q3KRC5-F1-model_v2	AlphaFold	Q3KRC5	1-640	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13696451

Promoter ID:

EPDNEW_R6976

Type:

initiation region

Name:

Dus3l_1

Description:

dihydrouridine synthase 3-like

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	9	10,294,005 - 10,294,065	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563228	AgrOrtholog
BioCyc Gene	G2FUF-28513	BioCyc
Ensembl Genes	ENSRNOG00000050381	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000072703	ENTREZGENE
Gene3D-CATH	3.20.20.70	UniProtKB/Swiss-Prot
	Zinc finger, CCCH-type	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7932299	IMAGE-MGC_LOAD
InterPro	Aldolase_TIM	UniProtKB/Swiss-Prot
	DUS-like_FMN-bd	UniProtKB/Swiss-Prot
	tRNA_hU_synthase_CS	UniProtKB/Swiss-Prot
	Znf_CCCH	UniProtKB/Swiss-Prot
KEGG Report	rno:301122	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:124806	IMAGE-MGC_LOAD
NCBI Gene	301122	ENTREZGENE
PANTHER	TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE	UniProtKB/Swiss-Prot
	TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE	UniProtKB/Swiss-Prot
Pfam	Dus	UniProtKB/Swiss-Prot
PhenoGen	Dus3l	PhenoGen
PROSITE	UPF0034	UniProtKB/Swiss-Prot
	ZF_C3H1	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000050381	RatGTEx
Superfamily-SCOP	FMN-linked oxidoreductases	UniProtKB/Swiss-Prot
UniProt	A0A8I6ALK0	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LCL8_RAT	UniProtKB/TrEMBL
	A0ABK0LDR3_RAT	UniProtKB/TrEMBL
	A0ABK0LSE7_RAT	UniProtKB/TrEMBL
	A6KQU6	ENTREZGENE, UniProtKB/TrEMBL
	A6KQU7_RAT	UniProtKB/TrEMBL
	A6KQU8_RAT	UniProtKB/TrEMBL
	A6KQU9_RAT	UniProtKB/TrEMBL
	DUS3L_RAT	UniProtKB/Swiss-Prot
	M0RAY0	ENTREZGENE, UniProtKB/TrEMBL
	Q3KRC5	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-07-09	Dus3l	dihydrouridine synthase 3-like	Dus3l	dihydrouridine synthase 3-like (S. cerevisiae)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Dus3l	dihydrouridine synthase 3-like (S. cerevisiae)	MGC124806	similar to putative zinc finger protein	Symbol and Name updated	1299863	APPROVED
2006-02-09	MGC124806	similar to putative zinc finger protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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