Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tmem65 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Tmem65 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TMEM65 mRNA | CTD | PMID:36331819 | Tmem65 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Tmem65 (Mus musculus) | 6480464 | 1,2-Dimethylhydrazine results in decreased expression of TMEM65 mRNA | CTD | PMID:22206623 | Tmem65 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | affects expression | ISO | Tmem65 (Mus musculus) | 6480464 | 2,3',4,4',5-pentachlorobiphenyl affects the expression of TMEM65 mRNA | CTD | PMID:31388691 | Tmem65 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Tmem65 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TMEM65 mRNA | CTD | PMID:19465110 | Tmem65 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tmem65 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TMEM65 mRNA | CTD | PMID:21570461 | Tmem65 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of TMEM65 mRNA | CTD | PMID:32109520 | Tmem65 | Rat | 3,3',5,5'-tetrabromobisphenol A | increases expression | EXP | | 6480464 | tetrabromobisphenol A results in increased expression of TMEM65 mRNA | CTD | PMID:27914987 | Tmem65 | Rat | 4,4'-diaminodiphenylmethane | increases expression | EXP | | 6480464 | 4,4'-diaminodiphenylmethane results in increased expression of TMEM65 mRNA | CTD | PMID:25380136 | Tmem65 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TMEM65 mRNA | CTD | PMID:24780913 | Tmem65 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of TMEM65 mRNA | CTD | PMID:30047161 | Tmem65 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of TMEM65 mRNA | CTD | PMID:31881176 | Tmem65 | Rat | aconitine | decreases expression | EXP | | 6480464 | Aconitine results in decreased expression of TMEM65 protein | CTD | PMID:33236894 | Tmem65 | Rat | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of TMEM65 mRNA | CTD | PMID:28959563 | Tmem65 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of TMEM65 mRNA | CTD | PMID:30047161 | Tmem65 | Rat | antirheumatic drug | increases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of TMEM65 mRNA | CTD | PMID:24449571 | Tmem65 | Rat | aristolochic acid A | decreases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of TMEM65 mRNA | CTD | PMID:33212167 | Tmem65 | Rat | arsenite(3-) | multiple interactions | ISO | TMEM65 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to TMEM65 mRNA] | CTD | PMID:32406909 | Tmem65 | Rat | azoxystrobin | decreases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | azoxystrobin results in decreased expression of TMEM65 mRNA | CTD | PMID:33512557 | Tmem65 | Rat | benzo[a]pyrene | increases expression | ISO | Tmem65 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TMEM65 mRNA | CTD | PMID:22228805 | Tmem65 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TMEM65 mRNA | CTD | PMID:19150397 | Tmem65 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TMEM65 mRNA | CTD | PMID:25181051 | Tmem65 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TMEM65 mRNA | CTD | PMID:33296240 | Tmem65 | Rat | Butylbenzyl phthalate | increases methylation | ISO | Tmem65 (Mus musculus) | 6480464 | butylbenzyl phthalate results in increased methylation of TMEM65 intron | CTD | PMID:28392331 | Tmem65 | Rat | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TMEM65 more ... | CTD | PMID:39012411 | Tmem65 | Rat | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of TMEM65 mRNA | CTD | PMID:33453195 | Tmem65 | Rat | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TMEM65 more ... | CTD | PMID:39012411 | Tmem65 | Rat | carbamazepine | affects expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of TMEM65 mRNA | CTD | PMID:25979313 | Tmem65 | Rat | choline | multiple interactions | ISO | Tmem65 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Tmem65 | Rat | cobalt dichloride | decreases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of TMEM65 mRNA | CTD | PMID:19320972 | Tmem65 | Rat | coumestrol | multiple interactions | ISO | TMEM65 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TMEM65 mRNA | CTD | PMID:19167446 | Tmem65 | Rat | cyclosporin A | increases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TMEM65 mRNA | CTD | PMID:25562108 | Tmem65 | Rat | deguelin | decreases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | deguelin results in decreased expression of TMEM65 mRNA | CTD | PMID:33512557 | Tmem65 | Rat | dibutyl phthalate | increases expression | ISO | Tmem65 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of TMEM65 mRNA | CTD | PMID:21266533 | Tmem65 | Rat | doxorubicin | affects expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of TMEM65 protein | CTD | PMID:29385562 | Tmem65 | Rat | doxorubicin | decreases expression | ISO | Tmem65 (Mus musculus) | 6480464 | Doxorubicin results in decreased expression of TMEM65 mRNA | CTD | PMID:39631538 | Tmem65 | Rat | Enterolactone | multiple interactions | ISO | TMEM65 (Homo sapiens) | 6480464 | [Coumestrol co-treated with 2,3-bis(3'-hydroxybenzyl)butyrolactone] results in decreased expression of TMEM65 mRNA | CTD | PMID:19167446 | Tmem65 | Rat | ethyl methanesulfonate | increases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of TMEM65 mRNA | CTD | PMID:23649840 | Tmem65 | Rat | folic acid | multiple interactions | ISO | Tmem65 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Tmem65 | Rat | formaldehyde | increases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of TMEM65 mRNA | CTD | PMID:23649840 | Tmem65 | Rat | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of TMEM65 gene | CTD | PMID:22079235 | Tmem65 | Rat | glycidyl methacrylate | decreases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | glycidyl methacrylate results in decreased expression of TMEM65 protein | CTD | PMID:36641056 | Tmem65 | Rat | hydrogen peroxide | decreases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Hydrogen Peroxide results in decreased expression of TMEM65 mRNA | CTD | PMID:18951874 | Tmem65 | Rat | L-methionine | multiple interactions | ISO | Tmem65 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation more ... | CTD | PMID:20938992 | Tmem65 | Rat | malathion | increases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Malathion results in increased expression of TMEM65 mRNA | CTD | PMID:37047231 | Tmem65 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of TMEM65 mRNA | CTD | PMID:30047161 | Tmem65 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of TMEM65 gene | CTD | PMID:35440735 | Tmem65 | Rat | methyl methanesulfonate | increases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of TMEM65 mRNA | CTD | PMID:23649840 | Tmem65 | Rat | N-nitrosodimethylamine | increases expression | EXP | | 6480464 | Dimethylnitrosamine results in increased expression of TMEM65 mRNA | CTD | PMID:25380136 | Tmem65 | Rat | paracetamol | increases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TMEM65 mRNA | CTD | PMID:22230336 | Tmem65 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TMEM65 mRNA | CTD | PMID:33387578 | Tmem65 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tmem65 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TMEM65 mRNA; [perfluorooctane sulfonic more ... | CTD | PMID:36331819 | Tmem65 | Rat | pirinixic acid | increases expression | ISO | Tmem65 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of TMEM65 mRNA | CTD | PMID:18301758 | Tmem65 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of TMEM65 mRNA | CTD | PMID:30047161 | Tmem65 | Rat | pyrimidifen | decreases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | pyrimidifen results in decreased expression of TMEM65 mRNA | CTD | PMID:33512557 | Tmem65 | Rat | quercetin | decreases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of TMEM65 mRNA | CTD | PMID:21632981 | Tmem65 | Rat | rotenone | decreases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Rotenone results in decreased expression of TMEM65 mRNA | CTD | PMID:33512557 | Tmem65 | Rat | silver atom | decreases expression | ISO | Tmem65 (Mus musculus) | 6480464 | Silver results in decreased expression of TMEM65 mRNA | CTD | PMID:27131904 | Tmem65 | Rat | silver(0) | decreases expression | ISO | Tmem65 (Mus musculus) | 6480464 | Silver results in decreased expression of TMEM65 mRNA | CTD | PMID:27131904 | Tmem65 | Rat | sodium arsenite | increases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of TMEM65 mRNA | CTD | PMID:28595984 | Tmem65 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of TMEM65 mRNA | CTD | PMID:30047161 | Tmem65 | Rat | tetrachloromethane | increases expression | ISO | Tmem65 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of TMEM65 mRNA | CTD | PMID:31919559 | Tmem65 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of TMEM65 mRNA | CTD | PMID:34492290 | Tmem65 | Rat | thiram | increases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Thiram results in increased expression of TMEM65 mRNA | CTD | PMID:38568856 | Tmem65 | Rat | titanium dioxide | decreases methylation | ISO | Tmem65 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TMEM65 gene | CTD | PMID:35295148 | Tmem65 | Rat | valproic acid | decreases methylation | ISO | TMEM65 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of TMEM65 gene | CTD | PMID:29154799 | Tmem65 | Rat | valproic acid | affects expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of TMEM65 mRNA | CTD | PMID:25979313 | Tmem65 | Rat | valproic acid | increases expression | ISO | TMEM65 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TMEM65 mRNA | CTD | PMID:23179753|PMID:27188386|PMID:29154799 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||






















