Otulinl (OTU deubiquitinase with linear linkage specificity like) - Rat Genome Database

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Gene: Otulinl (OTU deubiquitinase with linear linkage specificity like) Rattus norvegicus
Analyze
Symbol: Otulinl
Name: OTU deubiquitinase with linear linkage specificity like
RGD ID: 1563205
Description: Predicted to be involved in protein linear deubiquitination. Predicted to be located in cytoplasmic side of endoplasmic reticulum membrane. Predicted to colocalize with nuclear envelope. Orthologous to human OTULINL (OTU deubiquitinase with linear linkage specificity like); INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Fam105a; family with sequence similarity 105, member A; hypothetical protein LOC310190; inactive ubiquitin thioesterase FAM105A; inactive ubiquitin thioesterase OTULINL; LOC310190; MGC124675; similar to hypothetical protein FLJ11127
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8280,136,411 - 80,164,290 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl280,139,262 - 80,166,962 (-)EnsemblGRCr8
mRatBN7.2278,405,994 - 78,433,860 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl278,408,593 - 78,433,838 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx285,480,442 - 85,505,508 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0283,602,174 - 83,627,242 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0278,650,691 - 78,675,816 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0280,383,642 - 80,408,672 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl280,383,643 - 80,408,672 (-)Ensemblrn6Rnor6.0
Rnor_5.02100,047,747 - 100,070,970 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4279,545,446 - 79,569,132 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera274,059,388 - 74,084,056 (-)NCBICelera
Cytogenetic Map2q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
actinomycin D  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
calcitriol  (ISO)
camptothecin  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
diallyl trisulfide  (ISO)
dioxygen  (EXP)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
fenvalerate  (EXP)
flutamide  (EXP)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
Licochalcone B  (ISO)
lidocaine  (EXP)
N-nitrosodimethylamine  (EXP)
niclosamide  (ISO)
nitrates  (ISO)
Nutlin-3  (ISO)
paracetamol  (EXP,ISO)
pentanal  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
propanal  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sulforaphane  (ISO)
testosterone  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:21873635   PMID:31056421  


Genomics

Comparative Map Data
Otulinl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8280,136,411 - 80,164,290 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl280,139,262 - 80,166,962 (-)EnsemblGRCr8
mRatBN7.2278,405,994 - 78,433,860 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl278,408,593 - 78,433,838 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx285,480,442 - 85,505,508 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0283,602,174 - 83,627,242 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0278,650,691 - 78,675,816 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0280,383,642 - 80,408,672 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl280,383,643 - 80,408,672 (-)Ensemblrn6Rnor6.0
Rnor_5.02100,047,747 - 100,070,970 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4279,545,446 - 79,569,132 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera274,059,388 - 74,084,056 (-)NCBICelera
Cytogenetic Map2q22NCBI
OTULINL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38514,581,792 - 14,616,180 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl514,581,792 - 14,616,180 (+)Ensemblhg38GRCh38
GRCh37514,581,901 - 14,616,289 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36514,634,932 - 14,664,205 (+)NCBIBuild 36Build 36hg18NCBI36
Celera514,604,627 - 14,639,018 (+)NCBICelera
Cytogenetic Map5p15.2NCBI
HuRef514,554,120 - 14,588,512 (+)NCBIHuRef
CHM1_1514,581,756 - 14,616,162 (+)NCBICHM1_1
T2T-CHM13v2.0514,520,844 - 14,555,231 (+)NCBIT2T-CHM13v2.0
Otulinl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391527,655,154 - 27,681,630 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1527,655,155 - 27,681,665 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381527,655,070 - 27,681,603 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1527,655,069 - 27,681,579 (-)Ensemblmm10GRCm38
MGSCv371527,586,025 - 27,611,253 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361527,600,995 - 27,626,223 (-)NCBIMGSCv36mm8
Celera1528,404,298 - 28,429,589 (-)NCBICelera
Cytogenetic Map15B1NCBI
cM Map1510.35NCBI
Otulinl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554263,912,360 - 3,919,176 (+)Ensembl
ChiLan1.0NW_0049554263,897,327 - 3,920,631 (+)NCBIChiLan1.0ChiLan1.0
OTULINL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2414,817,816 - 14,846,803 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1512,971,418 - 13,000,413 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0514,887,866 - 14,921,996 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1514,727,987 - 14,757,018 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl514,727,987 - 14,757,018 (+)EnsemblpanPan2panpan1.1
OTULINL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.134201,819 - 228,416 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl34203,382 - 228,326 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha344,695,176 - 4,721,689 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.034112,716 - 139,272 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl34112,858 - 139,413 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.134124,842 - 151,365 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.034124,685 - 151,181 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.034367,293 - 393,840 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Otulinl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213233,142,376 - 233,155,086 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366651,740,526 - 1,748,588 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366651,738,979 - 1,748,588 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OTULINL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl163,969,932 - 3,999,778 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1163,964,300 - 4,000,673 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2164,304,188 - 4,339,680 (+)NCBISscrofa10.2Sscrofa10.2susScr3
OTULINL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1414,280,578 - 14,318,206 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl414,300,065 - 14,307,321 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606414,178,868 - 14,252,659 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Otulinl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475111,609,609 - 11,630,706 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475111,609,538 - 11,631,446 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Otulinl
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13153,063,346 - 153,088,625 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Otulinl
336 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:138
Count of miRNA genes:112
Interacting mature miRNAs:122
Transcripts:ENSRNOT00000067638
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578777Stresp15Stress response QTL 1520.05blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)261556902106556902Rat
631500Bp99Blood pressure QTL 992.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)261051883104684275Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23675034481750344Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
5684996Bmd85Bone mineral density QTL 854.70.024tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)261051541105724065Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)240306867124537199Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
61465Bp13Blood pressure QTL 133.3blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)278269809104744824Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)241801363104744824Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24490435585286097Rat
2317058Aia13Adjuvant induced arthritis QTL 132.9joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)278269809123269809Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)244537979112567334Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979159440891Rat
5684990Bmd82Bone mineral density QTL 822.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)261051541105724065Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266683465677Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)25126685996266859Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)260861391105861391Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)238426449111295694Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23686864381868643Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)24490435589904355Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)261051541143746880Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat

Markers in Region
RH127325  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0280,383,697 - 80,383,889NCBIRnor6.0
RH 3.4 Map2386.7UniSTS
Cytogenetic Map2q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000067638   ⟹   ENSRNOP00000062926
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl280,139,932 - 80,164,244 (-)Ensembl
mRatBN7.2 Ensembl278,409,515 - 78,433,838 (-)Ensembl
Rnor_6.0 Ensembl280,383,643 - 80,408,672 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000094723   ⟹   ENSRNOP00000089086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl280,139,262 - 80,166,962 (-)Ensembl
mRatBN7.2 Ensembl278,408,845 - 78,418,072 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096292   ⟹   ENSRNOP00000095953
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl280,139,262 - 80,164,244 (-)Ensembl
mRatBN7.2 Ensembl278,408,593 - 78,433,838 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000112191   ⟹   ENSRNOP00000078647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl280,139,262 - 80,164,244 (-)Ensembl
mRatBN7.2 Ensembl278,408,593 - 78,433,838 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115351   ⟹   ENSRNOP00000090546
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl280,139,262 - 80,147,847 (-)Ensembl
mRatBN7.2 Ensembl278,408,845 - 78,418,072 (-)Ensembl
RefSeq Acc Id: NM_001037648   ⟹   NP_001032737
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8280,139,261 - 80,164,244 (-)NCBI
mRatBN7.2278,408,844 - 78,433,825 (-)NCBI
Rnor_6.0280,383,642 - 80,408,672 (-)NCBI
Rnor_5.02100,047,747 - 100,070,970 (-)NCBI
RGSC_v3.4279,545,446 - 79,569,132 (-)RGD
Celera274,059,388 - 74,084,056 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039102219   ⟹   XP_038958147
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8280,136,411 - 80,148,566 (-)NCBI
mRatBN7.2278,405,994 - 78,418,099 (-)NCBI
RefSeq Acc Id: XM_039102220   ⟹   XP_038958148
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8280,136,411 - 80,164,290 (-)NCBI
mRatBN7.2278,405,994 - 78,433,857 (-)NCBI
RefSeq Acc Id: XM_039102221   ⟹   XP_038958149
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8280,136,411 - 80,149,508 (-)NCBI
mRatBN7.2278,405,994 - 78,419,083 (-)NCBI
RefSeq Acc Id: XM_039102222   ⟹   XP_038958150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8280,136,411 - 80,144,916 (-)NCBI
mRatBN7.2278,405,994 - 78,414,497 (-)NCBI
RefSeq Acc Id: XM_039102223   ⟹   XP_038958151
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8280,140,865 - 80,164,290 (-)NCBI
mRatBN7.2278,410,449 - 78,433,859 (-)NCBI
RefSeq Acc Id: XM_039102224   ⟹   XP_038958152
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8280,140,744 - 80,164,290 (-)NCBI
mRatBN7.2278,410,330 - 78,433,860 (-)NCBI
RefSeq Acc Id: XM_063281751   ⟹   XP_063137821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8280,136,411 - 80,148,566 (-)NCBI
RefSeq Acc Id: NP_001032737   ⟸   NM_001037648
- UniProtKB: Q3B7D8 (UniProtKB/Swiss-Prot),   A0A8I6AC08 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000062926   ⟸   ENSRNOT00000067638
RefSeq Acc Id: XP_038958148   ⟸   XM_039102220
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AC08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958149   ⟸   XM_039102221
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AC08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958147   ⟸   XM_039102219
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A7F3 (UniProtKB/TrEMBL),   A0A8I6AC08 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038958150   ⟸   XM_039102222
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038958152   ⟸   XM_039102224
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038958151   ⟸   XM_039102223
- Peptide Label: isoform X6
Ensembl Acc Id: ENSRNOP00000090546   ⟸   ENSRNOT00000115351
Ensembl Acc Id: ENSRNOP00000089086   ⟸   ENSRNOT00000094723
Ensembl Acc Id: ENSRNOP00000095953   ⟸   ENSRNOT00000096292
Ensembl Acc Id: ENSRNOP00000078647   ⟸   ENSRNOT00000112191
RefSeq Acc Id: XP_063137821   ⟸   XM_063281751
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AC08 (UniProtKB/TrEMBL)
Protein Domains
OTU

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3B7D8-F1-model_v2 AlphaFold Q3B7D8 1-353 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691206
Promoter ID:EPDNEW_R1731
Type:multiple initiation site
Name:Fam105a_1
Description:family with sequence similarity 105, member A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0280,408,646 - 80,408,706EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563205 AgrOrtholog
BioCyc Gene G2FUF-53912 BioCyc
Ensembl Genes ENSRNOG00000012109 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000096292 ENTREZGENE
  ENSRNOT00000115351 ENTREZGENE
IMAGE_CLONE IMAGE:7930470 IMAGE-MGC_LOAD
InterPro FAM105 UniProtKB/Swiss-Prot
  OTULINL UniProtKB/Swiss-Prot
KEGG Report rno:310190 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124675 IMAGE-MGC_LOAD
NCBI Gene 310190 ENTREZGENE
PANTHER INACTIVE UBIQUITIN THIOESTERASE OTULINL UniProtKB/Swiss-Prot
  PTHR33662 UniProtKB/Swiss-Prot
Pfam Peptidase_C101 UniProtKB/Swiss-Prot
PhenoGen Otulinl PhenoGen
PRINTS PROTEINF105 UniProtKB/Swiss-Prot
  PROTEINF105A UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012109 RatGTEx
UniProt A0A8I6A7F3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AC08 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6APR4_RAT UniProtKB/TrEMBL
  A0A8I6G243_RAT UniProtKB/TrEMBL
  F1LN65_RAT UniProtKB/TrEMBL
  OTULL_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-03-22 Otulinl  OTU deubiquitinase with linear linkage specificity like  Fam105a  family with sequence similarity 105, member A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-04 Fam105a  family with sequence similarity 105, member A  LOC310190  similar to hypothetical protein FLJ11127  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC310190  similar to hypothetical protein FLJ11127      Symbol and Name status set to provisional 70820 PROVISIONAL