Ubr4 (ubiquitin protein ligase E3 component n-recognin 4) - Rat Genome Database

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Gene: Ubr4 (ubiquitin protein ligase E3 component n-recognin 4) Rattus norvegicus
Analyze
Symbol: Ubr4
Name: ubiquitin protein ligase E3 component n-recognin 4
RGD ID: 1563121
Description: Predicted to enable calmodulin binding activity; ubiquitin protein ligase activity; and ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in several processes, including negative regulation of HRI-mediated signaling; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein polyubiquitination. Predicted to act upstream of or within several processes, including HRI-mediated signaling; protein stabilization; and type I interferon-mediated signaling pathway. Predicted to be located in endosome. Predicted to be active in cytosol. Orthologous to human UBR4 (ubiquitin protein ligase E3 component n-recognin 4); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: E3 ubiquitin-protein ligase UBR4; N-recognin-4; Rbaf600; retinoblastoma-associated factor 600; RING-type E3 ubiquitin transferase UBR4; zinc finger UBR1-type protein 1; ZUBR1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85156,919,029 - 157,027,127 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5156,919,085 - 157,027,127 (+)EnsemblGRCr8
mRatBN7.25151,635,825 - 151,743,931 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5151,635,868 - 151,743,784 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5154,334,535 - 154,442,617 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05156,108,899 - 156,216,983 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05156,089,831 - 156,197,923 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05157,848,162 - 157,956,137 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,848,206 - 157,956,132 (+)Ensemblrn6Rnor6.0
Rnor_5.05161,587,889 - 161,695,849 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45158,181,988 - 158,289,896 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5150,015,471 - 150,123,406 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,2-dimethylhydrazine  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-bromohexadecanoic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
bazedoxifene  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
endosulfan  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
fipronil  (EXP)
flutamide  (EXP)
formaldehyde  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
furfural  (ISO)
glyphosate  (EXP)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
menadione  (ISO)
mercury dichloride  (EXP)
Mesaconitine  (EXP)
methamphetamine  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
miconazole  (ISO)
nefazodone  (EXP)
paracetamol  (ISO)
perfluorohexanesulfonic acid  (ISO)
pirinixic acid  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sunitinib  (ISO)
tebuconazole  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (EXP)
vinclozolin  (EXP)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO,ISS)
cytoskeleton  (IEA)
cytosol  (IEA,ISO)
endosome  (IEA,ISO,ISS)
nucleoplasm  (IEA,ISO)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:19182904   PMID:19946888   PMID:22871113   PMID:23861403   PMID:23932781   PMID:25034033   PMID:26514267   PMID:32357304  


Genomics

Comparative Map Data
Ubr4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85156,919,029 - 157,027,127 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5156,919,085 - 157,027,127 (+)EnsemblGRCr8
mRatBN7.25151,635,825 - 151,743,931 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5151,635,868 - 151,743,784 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx5154,334,535 - 154,442,617 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05156,108,899 - 156,216,983 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05156,089,831 - 156,197,923 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.05157,848,162 - 157,956,137 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5157,848,206 - 157,956,132 (+)Ensemblrn6Rnor6.0
Rnor_5.05161,587,889 - 161,695,849 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45158,181,988 - 158,289,896 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5150,015,471 - 150,123,406 (+)NCBICelera
Cytogenetic Map5q36NCBI
UBR4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38119,074,510 - 19,210,266 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl119,074,510 - 19,210,266 (-)Ensemblhg38GRCh38
GRCh37119,401,004 - 19,536,760 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36119,273,587 - 19,409,333 (-)NCBIBuild 36Build 36hg18NCBI36
Celera117,728,031 - 17,863,733 (-)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef117,647,560 - 17,783,291 (-)NCBIHuRef
CHM1_1119,510,241 - 19,646,027 (-)NCBICHM1_1
T2T-CHM13v2.0118,898,062 - 19,033,778 (-)NCBIT2T-CHM13v2.0
Ubr4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394139,107,970 - 139,216,844 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4139,079,920 - 139,216,899 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm384139,380,659 - 139,489,533 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4139,352,609 - 139,489,588 (+)Ensemblmm10GRCm38
MGSCv374138,936,574 - 139,045,448 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv364138,936,574 - 139,045,510 (+)NCBIMGSCv36mm8
Celera4141,168,298 - 141,277,468 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map470.66NCBI
Ubr4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495552757,335 - 185,727 (+)Ensembl
ChiLan1.0NW_00495552757,335 - 185,727 (+)NCBIChiLan1.0ChiLan1.0
UBR4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21207,905,024 - 208,041,492 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11207,021,725 - 207,158,238 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0118,032,528 - 18,168,954 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1119,079,774 - 19,215,578 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl119,079,779 - 19,215,578 (-)EnsemblpanPan2panpan1.1
UBR4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1279,403,336 - 79,536,385 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl279,403,351 - 79,536,208 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha275,918,229 - 76,050,601 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0280,026,056 - 80,158,846 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl280,026,058 - 80,158,843 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1276,786,822 - 76,919,297 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0277,797,029 - 77,929,785 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0278,867,492 - 78,999,935 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ubr4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505839,548,521 - 39,666,935 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364745,373,186 - 5,493,635 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364745,373,303 - 5,492,950 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBR4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl677,568,415 - 77,708,109 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1677,568,409 - 77,707,991 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2671,612,511 - 71,632,514 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UBR4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120113,354,561 - 113,493,936 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20113,355,676 - 113,494,386 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660332,673,759 - 2,811,993 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ubr4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247644,223,784 - 4,358,885 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247644,223,784 - 4,358,923 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ubr4
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1118,697,176 - 18,805,255 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ubr4
342 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:30
Count of miRNA genes:22
Interacting mature miRNAs:30
Transcripts:ENSRNOT00000039663
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5130249266172190305Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5116702075161702075Rat
1354583Despr3Despair related QTL34.980.0002locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)5132930505172190305Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5141212838172190305Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5149642129171146538Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5133789363172190305Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5134369199172190305Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5136631198172190305Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5112142946157142946Rat
1354631Swd2Spike wave discharge measurement QTL 23.640.0002brain electrophysiology trait (VT:0010557)brain total spike-and-wave discharge duration (CMO:0001740)5156396728172190305Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5112142946157142946Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5133081618172190305Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5149805999162987697Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5138002522170842766Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5112142946157142946Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5133270647172190305Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)5141764300172190305Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5133789363172190305Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5148093485172129029Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5125969677172190305Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5156396728167181764Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5131708216172190305Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5114131300159131300Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5149661912166600247Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5112142946157142946Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5116702075161702075Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5112142946157142946Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5116702075161702075Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5116702075161702075Rat
1298090Bp155Blood pressure QTL 1553.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)5156289283171137955Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5114131300159131300Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5133081618172190305Rat

Markers in Region
AI136251  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25151,669,609 - 151,669,801 (+)MAPPERmRatBN7.2
Rnor_6.05157,881,893 - 157,882,084NCBIRnor6.0
Rnor_5.05161,621,605 - 161,621,796UniSTSRnor5.0
RGSC_v3.45158,215,729 - 158,215,920UniSTSRGSC3.4
Celera5150,049,232 - 150,049,423UniSTS
RH 3.4 Map51047.2UniSTS
Cytogenetic Map5q36UniSTS
RH136771  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25151,743,805 - 151,743,898 (+)MAPPERmRatBN7.2
Rnor_6.05157,956,013 - 157,956,105NCBIRnor6.0
Rnor_5.05161,695,725 - 161,695,817UniSTSRnor5.0
RGSC_v3.45158,289,918 - 158,290,010UniSTSRGSC3.4
Celera5150,123,424 - 150,123,516UniSTS
Cytogenetic Map5q36UniSTS
RH138653  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25151,646,049 - 151,646,231 (+)MAPPERmRatBN7.2
Rnor_6.05157,858,388 - 157,858,569NCBIRnor6.0
Rnor_5.05161,598,100 - 161,598,281UniSTSRnor5.0
RGSC_v3.45158,192,171 - 158,192,352UniSTSRGSC3.4
Celera5150,025,657 - 150,025,838UniSTS
RH 3.4 Map51044.7UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000039663   ⟹   ENSRNOP00000032156
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5156,919,085 - 157,027,127 (+)Ensembl
mRatBN7.2 Ensembl5151,635,868 - 151,743,784 (+)Ensembl
Rnor_6.0 Ensembl5157,848,206 - 157,955,991 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082138   ⟹   ENSRNOP00000069008
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5156,919,085 - 157,027,127 (+)Ensembl
mRatBN7.2 Ensembl5151,635,868 - 151,743,784 (+)Ensembl
Rnor_6.0 Ensembl5157,848,211 - 157,956,132 (+)Ensembl
RefSeq Acc Id: NM_001395108   ⟹   NP_001382037
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,919,085 - 157,027,127 (+)NCBI
mRatBN7.25151,635,881 - 151,743,931 (+)NCBI
RefSeq Acc Id: XM_063287793   ⟹   XP_063143863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,919,031 - 157,027,121 (+)NCBI
RefSeq Acc Id: XM_063287794   ⟹   XP_063143864
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,919,031 - 157,027,121 (+)NCBI
RefSeq Acc Id: XM_063287795   ⟹   XP_063143865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,919,031 - 157,027,121 (+)NCBI
RefSeq Acc Id: XM_063287796   ⟹   XP_063143866
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,919,031 - 157,027,121 (+)NCBI
RefSeq Acc Id: XM_063287797   ⟹   XP_063143867
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,919,031 - 157,027,121 (+)NCBI
RefSeq Acc Id: XM_063287798   ⟹   XP_063143868
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,919,031 - 157,027,121 (+)NCBI
RefSeq Acc Id: XM_063287799   ⟹   XP_063143869
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,919,031 - 157,027,121 (+)NCBI
RefSeq Acc Id: XM_063287800   ⟹   XP_063143870
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,919,031 - 157,027,121 (+)NCBI
RefSeq Acc Id: XM_063287801   ⟹   XP_063143871
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,919,029 - 157,001,964 (+)NCBI
RefSeq Acc Id: XM_063287802   ⟹   XP_063143872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,969,808 - 157,027,121 (+)NCBI
RefSeq Acc Id: XM_063287803   ⟹   XP_063143873
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85156,919,031 - 157,027,121 (+)NCBI
Ensembl Acc Id: ENSRNOP00000069008   ⟸   ENSRNOT00000082138
Ensembl Acc Id: ENSRNOP00000032156   ⟸   ENSRNOT00000039663
RefSeq Acc Id: NP_001382037   ⟸   NM_001395108
- UniProtKB: A0A0G2JU89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143871   ⟸   XM_063287801
- Peptide Label: isoform X9
- UniProtKB: A0A0G2JU89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143863   ⟸   XM_063287793
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JU89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143866   ⟸   XM_063287796
- Peptide Label: isoform X4
- UniProtKB: A0A0G2JU89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143864   ⟸   XM_063287794
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JU89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143868   ⟸   XM_063287798
- Peptide Label: isoform X6
- UniProtKB: A0A0G2JU89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143869   ⟸   XM_063287799
- Peptide Label: isoform X7
- UniProtKB: A0A0G2JU89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143867   ⟸   XM_063287797
- Peptide Label: isoform X5
- UniProtKB: A0A0G2JU89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143865   ⟸   XM_063287795
- Peptide Label: isoform X3
- UniProtKB: A0A0G2JU89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143870   ⟸   XM_063287800
- Peptide Label: isoform X8
- UniProtKB: A0A0G2JU89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143873   ⟸   XM_063287803
- Peptide Label: isoform X11
- UniProtKB: A0A0G2JU89 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063143872   ⟸   XM_063287802
- Peptide Label: isoform X10
Protein Domains
UZI

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694211
Promoter ID:EPDNEW_R4733
Type:initiation region
Name:Ubr4_1
Description:ubiquitin protein ligase E3 component n-recognin 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05157,848,224 - 157,848,284EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563121 AgrOrtholog
BioCyc Gene G2FUF-39413 BioCyc
Ensembl Genes ENSRNOG00000018183 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000039663 ENTREZGENE
  ENSRNOT00000082138 ENTREZGENE
IMAGE_CLONE IMAGE:7365572 IMAGE-MGC_LOAD
InterPro ARM-type_fold UniProtKB/Swiss-Prot
  E3_Ub_ligase_UBR4 UniProtKB/Swiss-Prot
  E3_UBR4_N UniProtKB/Swiss-Prot
  UBR4-like UniProtKB/Swiss-Prot
  UBR4-like_dom UniProtKB/Swiss-Prot
  UBR4-like_UBR-box UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
  Znf_UBR UniProtKB/Swiss-Prot
MGC_CLONE MGC:109584 IMAGE-MGC_LOAD
NCBI Gene 313658 ENTREZGENE
PANTHER E3 UBIQUITIN-PROTEIN LIGASE UBR4 UniProtKB/Swiss-Prot
  PTHR21725 UniProtKB/Swiss-Prot
Pfam E3_UbLigase_R4 UniProtKB/Swiss-Prot
  E3_UBR4_N UniProtKB/Swiss-Prot
  UBR4 UniProtKB/Swiss-Prot
  zf-UBR UniProtKB/Swiss-Prot
PhenoGen Ubr4 PhenoGen
PROSITE UBR4_E3 UniProtKB/Swiss-Prot
  ZF_UBR UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000018183 RatGTEx
SMART ZnF_UBR1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48371 UniProtKB/Swiss-Prot
  SSF50978 UniProtKB/Swiss-Prot
UniProt A0A0G2JU89 ENTREZGENE, UniProtKB/TrEMBL
  F1LQI5_RAT UniProtKB/TrEMBL
  Q2TL32 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q5BJM4 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-23 Ubr4  ubiquitin protein ligase E3 component n-recognin 4  Rbaf600  ZUBR1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 Rbaf600  ZUBR1      Symbol and Name status set to provisional 70820 PROVISIONAL