Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Klhl15 | Rat | non-syndromic X-linked intellectual disability 103 | | ISO | KLHL15 (Homo sapiens) | 7240710 | | OMIM | | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Klhl15 | Rat | non-syndromic X-linked intellectual disability 103 | | ISO | KLHL15 (Homo sapiens) | 7240710 | | OMIM | | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| # | Reference Title | Reference Citation |
| 1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
| 2. | GOA pipeline | RGD automated data pipeline |
| 3. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
| Klhl15 (Rattus norvegicus - Norway rat) |
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| KLHL15 (Homo sapiens - human) |
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| Klhl15 (Mus musculus - house mouse) |
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| Klhl15 (Chinchilla lanigera - long-tailed chinchilla) |
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| KLHL15 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| KLHL15 (Canis lupus familiaris - dog) |
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| Klhl15 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| KLHL15 (Sus scrofa - pig) |
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| KLHL15 (Chlorocebus sabaeus - green monkey) |
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| Klhl15 (Heterocephalus glaber - naked mole-rat) |
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| Klhl15 (Rattus rattus - black rat) |
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Variants in Klhl15
179 total Variants
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| The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
| DXRat90 |
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| AU049895 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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musculoskeletal system
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nervous system
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renal system
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reproductive system
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respiratory system
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sensory system
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visual system
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|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 16 | 12 | 67 | 165 | 91 | 90 | 59 | 92 | 59 | 6 | 356 | 192 | 11 | 144 | 81 | 92 | 31 | 17 | 17 |
| Ensembl Acc Id: | ENSRNOT00000008558 ⟹ ENSRNOP00000008558 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000076315 ⟹ ENSRNOP00000068100 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000076530 ⟹ ENSRNOP00000068396 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| Ensembl Acc Id: | ENSRNOT00000127526 ⟹ ENSRNOP00000100615 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NM_001108021 ⟹ NP_001101491 | ||||||||||||||||||||||||||||
| RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_017602041 ⟹ XP_017457530 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_017602042 ⟹ XP_017457531 | ||||||||||||||||
| Type: | CODING | ||||||||||||||||
| Position: |
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| Sequence: |
| RefSeq Acc Id: | XM_039099705 ⟹ XP_038955633 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_039099706 ⟹ XP_038955634 | ||||||||||||
| Type: | CODING | ||||||||||||
| Position: |
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| RefSeq Acc Id: | XM_063279992 ⟹ XP_063136062 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063279993 ⟹ XP_063136063 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063279994 ⟹ XP_063136064 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063279995 ⟹ XP_063136065 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063279996 ⟹ XP_063136066 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063279997 ⟹ XP_063136067 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063279998 ⟹ XP_063136068 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063279999 ⟹ XP_063136069 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063280000 ⟹ XP_063136070 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063280001 ⟹ XP_063136071 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063280002 ⟹ XP_063136072 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063280003 ⟹ XP_063136073 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | XM_063280004 ⟹ XP_063136074 | ||||||||
| Type: | CODING | ||||||||
| Position: |
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| RefSeq Acc Id: | NP_001101491 ⟸ NM_001108021 |
| - UniProtKB: | D3ZA50 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | XP_017457531 ⟸ XM_017602042 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | D3ZA50 (UniProtKB/TrEMBL) |
| - Sequence: |
| RefSeq Acc Id: | XP_017457530 ⟸ XM_017602041 |
| - Peptide Label: | isoform X1 |
| - Sequence: |
| Ensembl Acc Id: | ENSRNOP00000008558 ⟸ ENSRNOT00000008558 |
| Ensembl Acc Id: | ENSRNOP00000068100 ⟸ ENSRNOT00000076315 |
| Ensembl Acc Id: | ENSRNOP00000068396 ⟸ ENSRNOT00000076530 |
| RefSeq Acc Id: | XP_038955633 ⟸ XM_039099705 |
| - Peptide Label: | isoform X1 |
| RefSeq Acc Id: | XP_038955634 ⟸ XM_039099706 |
| - Peptide Label: | isoform X1 |
| RefSeq Acc Id: | XP_063136070 ⟸ XM_063280000 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | D3ZA50 (UniProtKB/Swiss-Prot) |
| RefSeq Acc Id: | XP_063136065 ⟸ XM_063279995 |
| - Peptide Label: | isoform X1 |
| RefSeq Acc Id: | XP_063136069 ⟸ XM_063279999 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | D3ZA50 (UniProtKB/Swiss-Prot) |
| RefSeq Acc Id: | XP_063136073 ⟸ XM_063280003 |
| - Peptide Label: | isoform X4 |
| RefSeq Acc Id: | XP_063136074 ⟸ XM_063280004 |
| - Peptide Label: | isoform X5 |
| RefSeq Acc Id: | XP_063136064 ⟸ XM_063279994 |
| - Peptide Label: | isoform X1 |
| RefSeq Acc Id: | XP_063136067 ⟸ XM_063279997 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | D3ZA50 (UniProtKB/Swiss-Prot) |
| RefSeq Acc Id: | XP_063136068 ⟸ XM_063279998 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | D3ZA50 (UniProtKB/Swiss-Prot) |
| RefSeq Acc Id: | XP_063136066 ⟸ XM_063279996 |
| - Peptide Label: | isoform X1 |
| - UniProtKB: | D3ZA50 (UniProtKB/Swiss-Prot) |
| RefSeq Acc Id: | XP_063136063 ⟸ XM_063279993 |
| - Peptide Label: | isoform X1 |
| RefSeq Acc Id: | XP_063136071 ⟸ XM_063280001 |
| - Peptide Label: | isoform X2 |
| RefSeq Acc Id: | XP_063136062 ⟸ XM_063279992 |
| - Peptide Label: | isoform X1 |
| RefSeq Acc Id: | XP_063136072 ⟸ XM_063280002 |
| - Peptide Label: | isoform X3 |
| Ensembl Acc Id: | ENSRNOP00000100615 ⟸ ENSRNOT00000127526 |
| Name | Modeler | Protein Id | AA Range | Protein Structure |
| AF-D3ZA50-F1-model_v2 | AlphaFold | D3ZA50 | 1-604 | view protein structure |
| eQTL | View at Phenogen | |
| WGCNA | View at Phenogen | |
| Tissue/Strain Expression | View at Phenogen |
| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1563101 | AgrOrtholog |
| BioCyc Gene | G2FUF-2243 | BioCyc |
| Ensembl Genes | ENSRNOG00000006515 | Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000008558 | ENTREZGENE |
| ENSRNOT00000008558.6 | UniProtKB/Swiss-Prot | |
| Gene3D-CATH | 1.25.40.420 | UniProtKB/Swiss-Prot |
| 2.120.10.80 | UniProtKB/Swiss-Prot | |
| Potassium Channel Kv1.1, Chain A | UniProtKB/Swiss-Prot | |
| InterPro | BACK | UniProtKB/Swiss-Prot |
| BTB-kelch_protein | UniProtKB/Swiss-Prot | |
| BTB/POZ_dom | UniProtKB/Swiss-Prot | |
| Kelch-typ_b-propeller | UniProtKB/Swiss-Prot | |
| Kelch_1 | UniProtKB/Swiss-Prot | |
| KLHL15 | UniProtKB/Swiss-Prot | |
| KLHL15_BACK | UniProtKB/Swiss-Prot | |
| SKP1/BTB/POZ_sf | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:314111 | UniProtKB/Swiss-Prot |
| NCBI Gene | 314111 | ENTREZGENE |
| PANTHER | LD33804P | UniProtKB/Swiss-Prot |
| PTHR45632:SF12 | UniProtKB/Swiss-Prot | |
| Pfam | BACK | UniProtKB/Swiss-Prot |
| BTB | UniProtKB/Swiss-Prot | |
| Kelch_1 | UniProtKB/Swiss-Prot | |
| Kelch_6 | UniProtKB/Swiss-Prot | |
| PhenoGen | Klhl15 | PhenoGen |
| PIRSF | Kelch-like_protein_gigaxonin | UniProtKB/Swiss-Prot |
| PROSITE | BTB | UniProtKB/Swiss-Prot |
| RatGTEx | ENSRNOG00000006515 | RatGTEx |
| SMART | BACK | UniProtKB/Swiss-Prot |
| BTB | UniProtKB/Swiss-Prot | |
| Kelch | UniProtKB/Swiss-Prot | |
| Superfamily-SCOP | SSF117281 | UniProtKB/Swiss-Prot |
| SSF54695 | UniProtKB/Swiss-Prot | |
| UniProt | A0ABK0LGJ3_RAT | UniProtKB/TrEMBL |
| D3ZA50 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2013-02-06 | Klhl15 | kelch-like family member 15 | Klhl15 | kelch-like 15 (Drosophila) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-04-30 | Klhl15 | kelch-like 15 (Drosophila) | Klhl15_predicted | kelch-like 15 (Drosophila) (predicted) | 'predicted' is removed | 2292626 | APPROVED |
| 2006-03-30 | Klhl15_predicted | kelch-like 15 (Drosophila) (predicted) | RGD1563101_predicted | similar to Kelch-like 15 (predicted) | Symbol and Name updated | 1299863 | APPROVED |
| 2006-03-07 | RGD1563101_predicted | similar to Kelch-like 15 (predicted) | LOC314111 | similar to Kelch-like 15 | Symbol and Name status set to approved | 1299863 | APPROVED |
| 2006-02-09 | LOC314111 | similar to Kelch-like 15 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |