Sowahd (sosondowah ankyrin repeat domain family member D) - Rat Genome Database

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Pathways
Gene: Sowahd (sosondowah ankyrin repeat domain family member D) Rattus norvegicus
Analyze
Symbol: Sowahd
Name: sosondowah ankyrin repeat domain family member D
RGD ID: 1563086
Description: Orthologous to human SOWAHD (sosondowah ankyrin repeat domain family member D); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Ankrd58; ankyrin repeat domain 58; ankyrin repeat domain-containing protein 58; ankyrin repeat domain-containing protein SOWAHD; LOC367699; MGC188007; RGD1563086; similar to hypothetical protein A630014H24
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X121,157,720 - 121,159,350 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX121,157,720 - 121,159,342 (+)EnsemblGRCr8
mRatBN7.2X116,292,030 - 116,293,660 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX116,292,030 - 116,293,660 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX118,395,493 - 118,397,123 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X121,964,642 - 121,966,272 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X119,510,653 - 119,512,283 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X123,662,477 - 123,664,107 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX123,662,477 - 123,664,107 (+)Ensemblrn6Rnor6.0
Rnor_5.0X123,806,187 - 123,807,817 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X7,869,389 - 7,871,013 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX115,519,909 - 115,521,539 (+)NCBICelera
Cytogenetic MapXq35NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
COVID-19  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15632090  


Genomics

Comparative Map Data
Sowahd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X121,157,720 - 121,159,350 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX121,157,720 - 121,159,342 (+)EnsemblGRCr8
mRatBN7.2X116,292,030 - 116,293,660 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX116,292,030 - 116,293,660 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX118,395,493 - 118,397,123 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X121,964,642 - 121,966,272 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X119,510,653 - 119,512,283 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X123,662,477 - 123,664,107 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX123,662,477 - 123,664,107 (+)Ensemblrn6Rnor6.0
Rnor_5.0X123,806,187 - 123,807,817 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X7,869,389 - 7,871,013 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX115,519,909 - 115,521,539 (+)NCBICelera
Cytogenetic MapXq35NCBI
SOWAHD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X119,758,588 - 119,760,202 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX119,758,588 - 119,760,202 (+)Ensemblhg38GRCh38
GRCh37X118,892,551 - 118,894,165 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X118,776,604 - 118,778,155 (+)NCBIBuild 36Build 36hg18NCBI36
CeleraX119,347,218 - 119,348,807 (+)NCBICelera
Cytogenetic MapXq24NCBI
HuRefX108,385,430 - 108,387,019 (+)NCBIHuRef
CHM1_1X118,803,475 - 118,805,064 (+)NCBICHM1_1
T2T-CHM13v2.0X118,133,706 - 118,135,320 (+)NCBIT2T-CHM13v2.0
Sowahd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X36,312,498 - 36,314,071 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX36,312,498 - 36,314,071 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X37,048,845 - 37,050,418 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX37,048,845 - 37,050,418 (+)Ensemblmm10GRCm38
MGSCv37X34,588,840 - 34,590,413 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X33,480,290 - 33,481,863 (+)NCBIMGSCv36mm8
CeleraX23,772,475 - 23,774,048 (+)NCBICelera
Cytogenetic MapXA3.3NCBI
cM MapX21.46NCBI
Sowahd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955534220,999 - 222,550 (-)NCBIChiLan1.0ChiLan1.0
SOWAHD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X119,138,761 - 119,141,558 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X119,141,759 - 119,146,186 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X108,789,104 - 108,792,522 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X119,215,998 - 119,217,927 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX119,216,380 - 119,217,340 (+)EnsemblpanPan2panpan1.1
SOWAHD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Dog10K_Boxer_TashaX77,851,406 - 77,853,207 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X93,516,238 - 93,518,039 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX93,516,469 - 93,517,458 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X90,968,480 - 90,970,281 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X92,728,192 - 92,729,993 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X92,457,073 - 92,458,643 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Sowahd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X90,823,115 - 90,824,839 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647910,162,691 - 10,164,190 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SOWAHD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX98,156,970 - 98,158,807 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X98,154,437 - 98,158,808 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X113,453,594 - 113,455,343 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SOWAHD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606532,537,986 - 32,539,413 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sowahd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248953,730,043 - 3,732,120 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Sowahd
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X103,231,102 - 103,232,724 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Sowahd
13 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:273
Count of miRNA genes:173
Interacting mature miRNAs:197
Transcripts:ENSRNOT00000075314
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X97528096142528096Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X120028026141353710Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X120028026141353710Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX105359969157758123Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X80434318125434318Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X105468858125434318Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118973754157758123Rat
2302047Pia34Pristane induced arthritis QTL 345.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)1996916163141916163Rat

Markers in Region
UniSTS:488532  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X116,292,100 - 116,293,543 (+)MAPPERmRatBN7.2
Rnor_6.0X123,662,548 - 123,663,990NCBIRnor6.0
Rnor_5.0X123,806,258 - 123,807,700UniSTSRnor5.0
RGSC_v3.4X7,869,506 - 7,870,948UniSTSRGSC3.4
CeleraX115,519,980 - 115,521,422UniSTS
Cytogenetic MapXq12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
3 3 34 84 62 59 37 59 37 6 214 117 10 57 55 81 22 9 9

Sequence


Ensembl Acc Id: ENSRNOT00000075314   ⟹   ENSRNOP00000066104
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX121,157,720 - 121,159,342 (+)Ensembl
mRatBN7.2 EnsemblX116,292,030 - 116,293,660 (+)Ensembl
Rnor_6.0 EnsemblX123,662,477 - 123,664,107 (+)Ensembl
RefSeq Acc Id: NM_001173373   ⟹   NP_001166844
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X121,157,720 - 121,159,350 (+)NCBI
mRatBN7.2X116,292,030 - 116,293,660 (+)NCBI
Rnor_6.0X123,662,477 - 123,664,107 (+)NCBI
Rnor_5.0X123,806,187 - 123,807,817 (+)NCBI
CeleraX115,519,909 - 115,521,539 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001166844 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI62046 (Get FASTA)   NCBI Sequence Viewer  
  EDM10835 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000066104
  ENSRNOP00000066104.1
RefSeq Acc Id: NP_001166844   ⟸   NM_001173373
- UniProtKB: B1WC89 (UniProtKB/TrEMBL),   M0R9D6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000066104   ⟸   ENSRNOT00000075314

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1WC89-F1-model_v2 AlphaFold B1WC89 1-328 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563086 AgrOrtholog
BioCyc Gene G2FUF-1300 BioCyc
Ensembl Genes ENSRNOG00000049392 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000075314 ENTREZGENE
  ENSRNOT00000075314.4 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7107377 IMAGE-MGC_LOAD
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
KEGG Report rno:367699 UniProtKB/TrEMBL
MGC_CLONE MGC:188007 IMAGE-MGC_LOAD
NCBI Gene 367699 ENTREZGENE
PANTHER ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN SOWAHD UniProtKB/TrEMBL
  UNCHARACTERIZED UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
PhenoGen Sowahd PhenoGen
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000049392 RatGTEx
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP ANK UniProtKB/TrEMBL
UniProt B1WC89 ENTREZGENE, UniProtKB/TrEMBL
  M0R9D6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-07-13 Sowahd  sosondowah ankyrin repeat domain family member D  Ankrd58  ankyrin repeat domain 58  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Ankrd58  ankyrin repeat domain 58  RGD1563086_predicted  similar to hypothetical protein A630014H24 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1563086_predicted  similar to hypothetical protein A630014H24 (predicted)  LOC367699  similar to hypothetical protein A630014H24  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC367699  similar to hypothetical protein A630014H24      Symbol and Name status set to provisional 70820 PROVISIONAL