Mageb5 (MAGE family member B5) - Rat Genome Database

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Gene: Mageb5 (MAGE family member B5) Rattus norvegicus
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Symbol: Mageb5
Name: MAGE family member B5
RGD ID: 1563078
Description: Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to human MAGEB5 (MAGE family member B5); INTERACTS WITH bisphenol A; bis(2-ethylhexyl) phthalate (ortholog); genistein (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC302442; Mageb17; melanoma antigen family B, 17; melanoma antigen family B, 5; melanoma antigen, family B, 5; melanoma-associated antigen B5; RGD1563078; similar to Melanoma-associated antigen B1 (MAGE-B1 antigen)
RGD Orthologs
Human
Mouse
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X60,454,155 - 60,457,732 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX60,454,155 - 60,457,732 (-)EnsemblGRCr8
mRatBN7.2X56,478,928 - 56,495,736 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX56,478,948 - 56,496,921 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX57,838,640 - 57,842,217 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X61,338,991 - 61,342,568 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X58,957,078 - 58,960,659 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X60,849,005 - 60,852,583 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX60,849,014 - 60,852,583 (-)Ensemblrn6Rnor6.0
Rnor_5.0X61,434,582 - 61,438,151 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X79,036,635 - 79,040,204 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX56,969,057 - 56,972,630 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Mageb5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X60,454,155 - 60,457,732 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX60,454,155 - 60,457,732 (-)EnsemblGRCr8
mRatBN7.2X56,478,928 - 56,495,736 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX56,478,948 - 56,496,921 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX57,838,640 - 57,842,217 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X61,338,991 - 61,342,568 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X58,957,078 - 58,960,659 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X60,849,005 - 60,852,583 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX60,849,014 - 60,852,583 (-)Ensemblrn6Rnor6.0
Rnor_5.0X61,434,582 - 61,438,151 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X79,036,635 - 79,040,204 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX56,969,057 - 56,972,630 (-)NCBICelera
Cytogenetic MapXq22NCBI
MAGEB5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X26,216,169 - 26,218,270 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX26,216,169 - 26,218,270 (+)Ensemblhg38GRCh38
GRCh37X26,234,286 - 26,236,387 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X26,144,178 - 26,146,308 (+)NCBIBuild 36Build 36hg18NCBI36
CeleraX30,361,713 - 30,363,673 (+)NCBICelera
Cytogenetic MapXp21.3NCBI
HuRefX23,972,837 - 23,974,938 (+)NCBIHuRef
CHM1_1X26,265,947 - 26,268,048 (+)NCBICHM1_1
T2T-CHM13v2.0X25,803,479 - 25,805,580 (+)NCBIT2T-CHM13v2.0
Mageb5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X90,823,214 - 90,826,582 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX90,823,150 - 90,826,624 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X91,779,608 - 91,782,976 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX91,779,544 - 91,783,018 (-)Ensemblmm10GRCm38
MGSCv37X89,024,947 - 89,028,315 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X88,032,263 - 88,035,737 (-)NCBIMGSCv36mm8
CeleraX59,203,706 - 59,207,074 (+)NCBICelera
Cytogenetic MapXC2NCBI
cM MapX40.5NCBI
MAGEB5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X28,019,097 - 28,021,331 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X28,022,478 - 28,024,711 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X18,817,671 - 18,819,765 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X26,181,734 - 26,183,828 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX26,182,861 - 26,183,688 (+)EnsemblpanPan2panpan1.1
LOC119868182
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ROS_Cfam_1.0X21,604,761 - 21,607,157 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1X21,636,247 - 21,638,639 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X21,675,916 - 21,678,313 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X21,729,260 - 21,731,656 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC100513636
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X22,188,608 - 22,189,561 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X23,771,151 - 23,774,263 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAGEB5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X24,682,389 - 24,686,715 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605626,614,855 - 26,616,970 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:46
Count of miRNA genes:44
Interacting mature miRNAs:44
Transcripts:ENSRNOT00000004145
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat


Expression

RNA-SEQ Expression

appendage
mesenchyme
reproductive system
1 1 40

Sequence


Ensembl Acc Id: ENSRNOT00000004145   ⟹   ENSRNOP00000004145
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX60,454,155 - 60,457,732 (-)Ensembl
mRatBN7.2 EnsemblX56,478,948 - 56,482,542 (-)Ensembl
Rnor_6.0 EnsemblX60,849,014 - 60,852,583 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109132   ⟹   ENSRNOP00000092798
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX56,478,948 - 56,496,921 (-)Ensembl
RefSeq Acc Id: NM_001106946   ⟹   NP_001100416
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X60,454,155 - 60,457,732 (-)NCBI
mRatBN7.2X56,478,947 - 56,482,524 (-)NCBI
Rnor_6.0X60,849,014 - 60,852,583 (-)NCBI
Rnor_5.0X61,434,582 - 61,438,151 (-)NCBI
RGSC_v3.4X79,036,635 - 79,040,204 (-)RGD
CeleraX56,969,057 - 56,972,630 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100416 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL96026 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004145
  ENSRNOP00000004145.2
RefSeq Acc Id: NP_001100416   ⟸   NM_001106946
- UniProtKB: D4A972 (UniProtKB/TrEMBL),   A6IPY7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004145   ⟸   ENSRNOT00000004145
Ensembl Acc Id: ENSRNOP00000092798   ⟸   ENSRNOT00000109132
Protein Domains
MAGE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A972-F1-model_v2 AlphaFold D4A972 1-366 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563078 AgrOrtholog
BioCyc Gene G2FUF-2294 BioCyc
Ensembl Genes ENSRNOG00000003110 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004145 ENTREZGENE
  ENSRNOT00000004145.5 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1200 UniProtKB/TrEMBL
  1.10.10.1210 UniProtKB/TrEMBL
InterPro MAGE UniProtKB/TrEMBL
  MAGE UniProtKB/TrEMBL
  MAGE_WH1 UniProtKB/TrEMBL
  MAGE_WH2 UniProtKB/TrEMBL
KEGG Report rno:302442 UniProtKB/TrEMBL
NCBI Gene 302442 ENTREZGENE
PANTHER MELANOMA-ASSOCIATED ANTIGEN B5 UniProtKB/TrEMBL
  PTHR11736 UniProtKB/TrEMBL
Pfam MAGE UniProtKB/TrEMBL
PhenoGen Mageb5 PhenoGen
PROSITE MAGE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003110 RatGTEx
SMART MAGE UniProtKB/TrEMBL
UniProt A6IPY7 ENTREZGENE, UniProtKB/TrEMBL
  D4A972 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-19 Mageb5  MAGE family member B5  Mageb5  melanoma antigen family B, 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-07-21 Mageb5  melanoma antigen family B, 5  Mageb17  melanoma antigen family B, 17  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-01-22 Mageb17  melanoma antigen family B, 17  Mageb5  melanoma antigen, family B, 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Mageb5  melanoma antigen, family B, 5   Mageb5_predicted  melanoma antigen, family B, 5 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Mageb5_predicted  melanoma antigen, family B, 5 (predicted)  RGD1563078_predicted  similar to Melanoma-associated antigen B1 (MAGE-B1 antigen) (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-10 RGD1563078_predicted  similar to Melanoma-associated antigen B1 (MAGE-B1 antigen) (predicted)    similar to Melanoma-associated antigen B1 (MAGE-B1 antigen) (MAGE-XP antigen) (DSS-AHC critical interval MAGE superfamily 10) (DAM10) (predicted)  Name updated 1299863 APPROVED
2006-03-07 RGD1563078_predicted  similar to Melanoma-associated antigen B1 (MAGE-B1 antigen) (MAGE-XP antigen) (DSS-AHC critical interval MAGE superfamily 10) (DAM10) (predicted)  LOC302442  similar to Melanoma-associated antigen B1 (MAGE-B1 antigen) (MAGE-XP antigen) (DSS-AHC critical interval MAGE superfamily 10) (DAM10)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC302442  similar to Melanoma-associated antigen B1 (MAGE-B1 antigen) (MAGE-XP antigen) (DSS-AHC critical interval MAGE superfamily 10) (DAM10)      Symbol and Name status set to provisional 70820 PROVISIONAL