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Gene: Gpr137c (G protein-coupled receptor 137C) Rattus norvegicus

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Symbol:

Gpr137c

Name:

G protein-coupled receptor 137C

RGD ID:

1563070

Description:

Predicted to be involved in positive regulation of TORC1 signaling. Predicted to be located in lysosome and membrane. Predicted to be active in lysosomal membrane. Orthologous to human GPR137C (G protein-coupled receptor 137C); INTERACTS WITH acrylamide; bisphenol A; paracetamol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

hypothetical protein LOC305812; integral membrane protein GPR137C; LOC305812; RGD1563070; similar to hypothetical protein

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GPR137C (G protein-coupled receptor 137C)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Mus musculus (house mouse):	Gpr137c (G protein-coupled receptor 137C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gpr137c (G protein-coupled receptor 137C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GPR137C (G protein-coupled receptor 137C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GPR137C (G protein-coupled receptor 137C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gpr137c (G protein-coupled receptor 137C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GPR137C (G protein-coupled receptor 137C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GPR137C (G protein-coupled receptor 137C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gpr137c (G protein-coupled receptor 137C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Gpr137c (G protein-coupled receptor 137C)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CCDC190 (coiled-coil domain containing 190)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	GPR137C (G protein-coupled receptor 137C)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Gpr137c (G protein-coupled receptor 137C)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gpr137c	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	gpr137c	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	gpr137c	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	20,905,923 - 20,972,318 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	20,905,958 - 20,970,541 (+)	Ensembl				GRCr8
mRatBN7.2	15	18,425,939 - 18,492,588 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	18,426,223 - 18,490,807 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	21,220,925 - 21,285,465 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	22,177,876 - 22,242,410 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	20,434,436 - 20,498,984 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	19,547,783 - 19,615,717 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	19,547,871 - 19,614,805 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	23,513,041 - 23,580,026 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	21,099,112 - 21,164,296 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	18,854,866 - 18,919,091 (+)	NCBI		Celera
Cytogenetic Map	15	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

1,2-dichloroethane (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,4'-trichlorobiphenyl (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2-hydroxypropanoic acid (ISO)

3,4-methylenedioxymethamphetamine (ISO)

5-fluorouracil (ISO)

acrylamide (EXP)

aflatoxin B1 (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

buta-1,3-diene (ISO)

Butylbenzyl phthalate (ISO)

chlorpyrifos (ISO)

copper(II) sulfate (ISO)

leflunomide (ISO)

methylmercury chloride (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

PCB138 (ISO)

potassium chromate (ISO)

rac-lactic acid (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sodium lactate (ISO)

sulforaphane (ISO)

sunitinib (ISO)

theophylline (ISO)

titanium dioxide (ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triptonide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of TORC1 signaling (IBA)

Cellular Component

lysosomal membrane (IBA,IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:31036939

Genomics

Comparative Map Data

Gpr137c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	20,905,923 - 20,972,318 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	15	20,905,958 - 20,970,541 (+)	Ensembl				GRCr8
mRatBN7.2	15	18,425,939 - 18,492,588 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	18,426,223 - 18,490,807 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	15	21,220,925 - 21,285,465 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	22,177,876 - 22,242,410 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	20,434,436 - 20,498,984 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	19,547,783 - 19,615,717 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	19,547,871 - 19,614,805 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	15	23,513,041 - 23,580,026 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	15	21,099,112 - 21,164,296 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	15	18,854,866 - 18,919,091 (+)	NCBI		Celera
Cytogenetic Map	15	p14	NCBI

GPR137C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	52,552,836 - 52,637,713 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	52,552,823 - 52,637,713 (+)	Ensembl			hg38	GRCh38
GRCh37	14	53,019,554 - 53,104,431 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	52,089,616 - 52,174,181 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	14	32,887,453 - 32,972,040 (+)	NCBI		Celera
Cytogenetic Map	14	q22.1	NCBI
HuRef	14	33,180,658 - 33,265,232 (+)	NCBI		HuRef
CHM1_1	14	52,958,836 - 53,043,371 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	46,760,682 - 46,845,552 (+)	NCBI		T2T-CHM13v2.0

Gpr137c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	45,457,142 - 45,520,192 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	45,457,174 - 45,520,182 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	14	45,219,685 - 45,282,735 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	45,219,717 - 45,282,725 (+)	Ensembl			mm10	GRCm38
MGSCv37	14	45,839,392 - 45,900,651 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	14	37,031,620 - 37,058,682 (+)	NCBI		MGSCv36	mm8
MGSCv36	14	44,141,594 - 44,144,820 (+)	NCBI		MGSCv36	mm8
Celera	14	41,400,322 - 41,460,736 (+)	NCBI		Celera
Cytogenetic Map	14	C1	NCBI
cM Map	14	22.82	NCBI

Gpr137c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	10,533,840 - 10,592,130 (-)	Ensembl
ChiLan1.0	NW_004955409	10,533,840 - 10,592,130 (-)	NCBI	ChiLan1.0	ChiLan1.0

GPR137C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	53,684,520 - 53,768,395 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	52,901,031 - 52,984,906 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	33,149,743 - 33,233,895 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	51,433,455 - 51,517,977 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	51,434,432 - 51,517,977 (+)	Ensembl			panPan2	panpan1.1

GPR137C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	28,795,725 - 28,861,011 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	28,795,732 - 28,858,831 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	28,541,129 - 28,605,993 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	28,962,174 - 29,027,085 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	28,961,769 - 29,027,065 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	28,635,912 - 28,701,141 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	28,708,002 - 28,773,385 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	29,036,968 - 29,102,101 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Gpr137c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	76,426,402 - 76,474,747 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936697	2,200,519 - 2,248,908 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936697	2,200,557 - 2,248,902 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPR137C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	182,203,309 - 182,261,516 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	1	182,203,185 - 182,263,753 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	202,424,885 - 202,431,476 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GPR137C
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	29,628,120 - 29,713,969 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666053	17,905,411 - 17,991,472 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gpr137c
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624731	16,478,057 - 16,531,075 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624731	16,476,556 - 16,531,144 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Gpr137c
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	12	77,759,771 - 77,816,853 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Gpr137c
690 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	44
Count of miRNA genes:	43
Interacting mature miRNAs:	44
Transcripts:	ENSRNOT00000036235
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1641913	Colcr2	Colorectal carcinoma resistance QTL 2	6.57	0.0197	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	15	2315759	47315759	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	19155762	87086765	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	2785923	47785923	Rat
5684946	Bss98	Bone structure and strength QTL 98	3.9	0.0026	tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	15	1	39411584	Rat
1354657	Despr13	Despair related QTL 13		0.0022	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	15	1	32342855	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	14926594	71614418	Rat
1641887	Alcrsp14	Alcohol response QTL 14			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	15	1	44836456	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2315759	53331089	Rat
5685002	Bss103	Bone structure and strength QTL 103	2.8		tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	15	16911521	32439851	Rat

Markers in Region

RH144437

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	18,490,000 - 18,490,138 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	19,614,911 - 19,615,048	NCBI	Rnor6.0
Rnor_5.0	15	23,580,132 - 23,580,269	UniSTS	Rnor5.0
RGSC_v3.4	15	21,164,402 - 21,164,539	UniSTS	RGSC3.4
Celera	15	18,918,285 - 18,918,422	UniSTS
RH 3.4 Map	15	145.0	UniSTS
Cytogenetic Map	15	p14	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
7	11	64	149	48	47	18	56	18	6	249	144	5	136	72	88	29	16	16

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001134541	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093254	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274202	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063274203	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH474040	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000036235 ⟹ ENSRNOP00000031370

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	20,905,958 - 20,970,541 (+)	Ensembl
mRatBN7.2 Ensembl	15	18,426,223 - 18,490,807 (+)	Ensembl
Rnor_6.0 Ensembl	15	19,547,871 - 19,614,805 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000130843 ⟹ ENSRNOP00000106839

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	15	20,905,958 - 20,970,541 (+)	Ensembl

RefSeq Acc Id:

NM_001134541 ⟹ NP_001128013

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	20,905,958 - 20,970,541 (+)	NCBI
mRatBN7.2	15	18,426,223 - 18,490,807 (+)	NCBI
Rnor_6.0	15	19,547,783 - 19,615,717 (+)	NCBI
Rnor_5.0	15	23,513,041 - 23,580,026 (+)	NCBI
RGSC_v3.4	15	21,099,112 - 21,164,296 (+)	RGD
Celera	15	18,854,866 - 18,919,091 (+)	NCBI

Sequence:

show sequence

GGGCCGCAGGCTGGGGTGGGCGGGAGGTCCGGGGATCGCTCCGGCCGCTTCCTTCCCGCGCTCC
CTCCCGGTTGCTCACGTCCCCTCATGAGGGAGTCTGTGCCCGGGCCGGCGGCCGCCGCGGTCCC
CACGGCCGGCCGCGAACCCTCGACGCCCGGCGGGGGCGCCGTCGCGGCCTCGGGAGCCGCGGTT
CCCGGTTCGGTGCAGCTGGCGCTGAGCGTGCTGCACGCGCTGCTCTACGCCGCGCTCTTCGCCT
TTGCCTACCTGCAGCTGTGGCGGCTGCTCCTGTACCGCGAACGGCGGCTCAGTTACCAGAGCCT
CTGCCTCTTCCTGTGTCTCGCGTGGGCAGCGCTCAGGACCACGCTCTTCTCGGCCGCCTTCTCC
CTCAGCGGCTCTCTGCCCCTGCTGCGGCCACCCTCTCGCCTGCACTTCTTCCCGCACTGGCTGC
TCTACTGCTTCCCCTCCTGCCTCCAGTTCTCCACGCTCTGTCTCCTCAACCTCTACCTGGCAGA
GGTCATATGTAAAGTCAGATGTGCCACTGAACTTGACAAACACAAAATTCTACTGCATTTGGGC
TTTATTCTGGCAAGCCTTCTCTTCTTAGCAGTGAACTTGACCTGTGCAATGCTAGTCCACGGAG
ATGTCCCCGAAAATCAATTGAAATGGACTGTGTTTGTTCGAGCACTGGTTAACGATAGCTTGTT
TATTCTCTGTGCCATCTCTTTAGTTAGTTACATATGCAAAATTACAAAAATGTCATCAGCAAAT
GTCTACCTCGAATCAAAGGGTATGTCTCTGTGCCAGACTGTCATCGTGGGCTCTGTGGTCTTTC
TTCTCTACTCTTCCAGAGCTTGTTACAATCTGGTAGTGATCACCATATCGCAGGATACCTTAGA
GAGTCCATTTAATTATGGCTGGGATAATCTTTCAGATAAGGCTCGGGGGGAAGATGGAAATGGA
GTAGACTACATGGTCTTCGGAATGGTCCTCTTTCTGTGGGAGCATGTACCAGCATGGTCGGTGG
TACTATTTTTCCGGGCACAGAGATTAAACCAGAATCTGGCTCCCGCTGGCATGATCAGCAGCCA
CAGCTACAGCTCCAGGGCTTTCTTTTTTGACAATCCAAGACGGTATGACAGCGATGACGACTTG
CCAAGACTGGGGAGCTCACGGGAAGGAAGCTTATCAAACCCACAGACGCTGGGCTGGTACGGCA
CCATGGCCGGGTGTGGTGGCAGCACATACACAGTCACGCCCCCGCTGAACGGACCTGTGACGGA
CACTGCCCCTTTGCTCTTCACCTGCAGTAACTTGGATCTGAGGAACCACCATAGCTTATACGTA
ACCCCACAAAACTGACGGCTTCCCCAGGGCAGAAGCCTCGGACCGTTCTTCACGAACGCGTGCG
TGTTTTCGGCATCTTTAAACCCACCTGCATCAACACTGCATTACCTGTCCCGACTAACAAAGAA
CATCTGGAGGCGCGGCTGTGTTTCGTGGGTCTCCGCGTCCTGACCTCCGCCCAGCGAGACGTGA
AGTTTGCAGGAGAAGAGATTGGACGCTAAGGTACTCGGTGACCTCAGAACCTCCTAACTTTGGG
GCACCCTGCACACATTTGCATATTTGCACTTTTACCTATGTTCGGAAAGAATACTCTGCAGTCC
CCAAAGCCACACACTTGAGTATTCACACCAGAATATTACTGCACACTAAATCGGGAGGCAGTTT
TCCACACAAATCAAAACCTAGAAACCCGATGGCGTACTCCACCTTACCCAGTGACAGCTTTAAA
GTGTGATCAGTGCACAGAATTAAGGATTAAAAATGCATCTTTCTTTTTAAAAAAAAAAAATCTA
AAAACGTGTAACACTTAAGACAGTTTTTTAAAGCACGCTTTGAAAAGTGTCAATTTTAATTACT
CCATTATTTTAAACAAGGGATAGTAGAAACCCTTCAGGTGCTGCTGGCTGGCAGTGTTCTTTGG
AAAAGCCAGATGGGTTTCTTTGAGAGGAGCAGTAAGCCAAGAGGAGACTGTGTGGCTTTGAGGA
GGACTGGTCAAGTGGCTATTTTGTGACTAAGTAGCAGTTTAAGCATGATTCTTCCAGGCAATAG
TGACCTTTGCATAGGGGGCTTCGGTAAAATGTCTTGGGACTAAACAAGTTTACGGATGCGTTTA
GGGATTCTTCATTGGAAAAAGAAAAAGTGCTAAGTTAAAAACAGTATGTCTTTAAAAAGCATCC
AATTTGTCCAAAAGGGGGTGGAGCTCATCCT

hide sequence

RefSeq Acc Id:

XM_039093254 ⟹ XP_038949182

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	20,905,923 - 20,972,318 (+)	NCBI
mRatBN7.2	15	18,425,939 - 18,492,588 (+)	NCBI

RefSeq Acc Id:

XM_063274202 ⟹ XP_063130272

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	20,905,923 - 20,972,318 (+)	NCBI

RefSeq Acc Id:

XM_063274203 ⟹ XP_063130273

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	15	20,906,043 - 20,959,173 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001128013	(Get FASTA)	NCBI Sequence Viewer
	XP_038949182	(Get FASTA)	NCBI Sequence Viewer
	XP_063130272	(Get FASTA)	NCBI Sequence Viewer
	XP_063130273	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL88297	(Get FASTA)	NCBI Sequence Viewer
	EDL88298	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000031370
	ENSRNOP00000031370.7
	ENSRNOP00000106839.1

RefSeq Acc Id:

NP_001128013 ⟸ NM_001134541

- UniProtKB:

D3ZFP1 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MRESVPGPAAAAVPTAGREPSTPGGGAVAASGAAVPGSVQLALSVLHALLYAALFAFAYLQLWR
LLLYRERRLSYQSLCLFLCLAWAALRTTLFSAAFSLSGSLPLLRPPSRLHFFPHWLLYCFPSCL
QFSTLCLLNLYLAEVICKVRCATELDKHKILLHLGFILASLLFLAVNLTCAMLVHGDVPENQLK
WTVFVRALVNDSLFILCAISLVSYICKITKMSSANVYLESKGMSLCQTVIVGSVVFLLYSSRAC
YNLVVITISQDTLESPFNYGWDNLSDKARGEDGNGVDYMVFGMVLFLWEHVPAWSVVLFFRAQR
LNQNLAPAGMISSHSYSSRAFFFDNPRRYDSDDDLPRLGSSREGSLSNPQTLGWYGTMAGCGGS
TYTVTPPLNGPVTDTAPLLFTCSNLDLRNHHSLYVTPQN

hide sequence

Ensembl Acc Id:

ENSRNOP00000031370 ⟸ ENSRNOT00000036235

RefSeq Acc Id:	XP_038949182 ⟸ XM_039093254
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063130272 ⟸ XM_063274202
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063130273 ⟸ XM_063274203
- Peptide Label:	isoform X3

Ensembl Acc Id:

ENSRNOP00000106839 ⟸ ENSRNOT00000130843

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZFP1-F1-model_v2	AlphaFold	D3ZFP1	1-423	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1563070	AgrOrtholog
BioCyc Gene	G2FUF-14225	BioCyc
Ensembl Genes	ENSRNOG00000026328	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000036235	ENTREZGENE
	ENSRNOT00000036235.8	UniProtKB/TrEMBL
	ENSRNOT00000130843.1	UniProtKB/TrEMBL
InterPro	GPR137	UniProtKB/TrEMBL
KEGG Report	rno:305812	UniProtKB/TrEMBL
NCBI Gene	305812	ENTREZGENE
PANTHER	INTEGRAL MEMBRANE PROTEIN GPR137C	UniProtKB/TrEMBL
	PTHR15146	UniProtKB/TrEMBL
PhenoGen	Gpr137c	PhenoGen
RatGTEx	ENSRNOG00000026328	RatGTEx
UniProt	A0ABK0LU49_RAT	UniProtKB/TrEMBL
	D3ZFP1	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-05-25	Gpr137c	G protein-coupled receptor 137C	RGD1563070	similar to hypothetical protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	RGD1563070	similar to hypothetical protein	RGD1563070_predicted	similar to hypothetical protein (predicted)	'predicted' is removed	2292626	APPROVED
2006-03-07	RGD1563070_predicted	similar to hypothetical protein (predicted)	LOC305812	similar to hypothetical protein	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC305812	similar to hypothetical protein			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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