C5h6orf163 (similar to human chromosome 6 open reading frame 163) - Rat Genome Database

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Gene: C5h6orf163 (similar to human chromosome 6 open reading frame 163) Rattus norvegicus
Analyze
Symbol: C5h6orf163
Name: similar to human chromosome 6 open reading frame 163
RGD ID: 1563056
Description: Orthologous to human C6orf163 (chromosome 6 open reading frame 163); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC500434; RGD1563056; similar to hypothetical protein; uncharacterized protein C6orf163 homolog
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8554,113,073 - 54,132,787 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl554,112,859 - 54,126,074 (-)EnsemblGRCr8
mRatBN7.2549,316,784 - 49,329,164 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl549,316,785 - 49,327,159 (-)EnsemblmRatBN7.2
Rnor_6.0550,210,303 - 50,221,560 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl550,210,270 - 50,221,095 (-)Ensemblrn6Rnor6.0
Rnor_5.0554,779,257 - 54,790,497 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4551,367,429 - 51,377,546 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera548,063,283 - 48,074,104 (-)NCBICelera
Cytogenetic Map5q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
C5h6orf163
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8554,113,073 - 54,132,787 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl554,112,859 - 54,126,074 (-)EnsemblGRCr8
mRatBN7.2549,316,784 - 49,329,164 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl549,316,785 - 49,327,159 (-)EnsemblmRatBN7.2
Rnor_6.0550,210,303 - 50,221,560 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl550,210,270 - 50,221,095 (-)Ensemblrn6Rnor6.0
Rnor_5.0554,779,257 - 54,790,497 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4551,367,429 - 51,377,546 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera548,063,283 - 48,074,104 (-)NCBICelera
Cytogenetic Map5q21NCBI
C6orf163
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38687,344,813 - 87,365,463 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl687,344,813 - 87,365,463 (+)Ensemblhg38GRCh38
GRCh37688,054,531 - 88,075,181 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36688,113,939 - 88,131,900 (+)NCBIBuild 36Build 36hg18NCBI36
Celera688,473,243 - 88,493,854 (+)NCBICelera
Cytogenetic Map6q15NCBI
HuRef685,271,026 - 85,291,637 (+)NCBIHuRef
CHM1_1688,152,090 - 88,172,701 (+)NCBICHM1_1
T2T-CHM13v2.0688,553,675 - 88,574,324 (+)NCBIT2T-CHM13v2.0
Gm136
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39434,743,788 - 34,756,259 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl434,743,784 - 34,756,263 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38434,743,788 - 34,756,259 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl434,743,784 - 34,756,263 (-)Ensemblmm10GRCm38
MGSCv37434,691,037 - 34,703,508 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36434,932,675 - 34,945,146 (-)NCBIMGSCv36mm8
Celera434,472,151 - 34,480,837 (-)NCBICelera
Cytogenetic Map4A5NCBI
cM Map416.86NCBI
C5H6orf163
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25107,427,102 - 107,448,611 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16105,322,023 - 105,343,444 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0685,222,392 - 85,243,937 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1688,498,586 - 88,519,172 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl688,498,586 - 88,519,172 (+)EnsemblpanPan2panpan1.1
C12H6orf163
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11246,848,095 - 46,869,020 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1246,848,783 - 46,869,012 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1246,657,059 - 46,677,373 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01247,654,135 - 47,674,311 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1247,654,014 - 47,674,303 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11246,946,609 - 46,966,924 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01246,873,968 - 46,894,204 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01247,063,303 - 47,083,624 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
CUNH6orf163
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494681,979,912 - 82,001,460 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365104,468,044 - 4,490,729 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365104,469,302 - 4,491,653 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C1H6orf163
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl155,765,575 - 55,789,195 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1155,765,627 - 55,788,627 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2162,456,446 - 62,481,836 (+)NCBISscrofa10.2Sscrofa10.2susScr3
C13H6orf163
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11311,829,881 - 11,851,459 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1311,830,343 - 11,851,300 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040188,084,272 - 188,107,041 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH6orf163
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247997,001,853 - 7,025,411 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247997,001,059 - 7,027,916 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
C1H6orf163
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1163,173,179 - 63,183,455 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in C5h6orf163
165 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:90
Count of miRNA genes:77
Interacting mature miRNAs:83
Transcripts:ENSRNOT00000012164
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1578774Tcas8Tongue tumor susceptibility QTL 83.47tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)51570745160707451Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51460607859606078Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2303577Gluco47Glucose level QTL 473blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51652001961520019Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 7 63 148 76 75 44 79 44 6 316 174 11 127 78 92 31 10 10

Sequence


Ensembl Acc Id: ENSRNOT00000012164   ⟹   ENSRNOP00000012164
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl554,112,859 - 54,123,389 (-)Ensembl
mRatBN7.2 Ensembl549,316,785 - 49,327,159 (-)Ensembl
Rnor_6.0 Ensembl550,210,270 - 50,221,095 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000144574   ⟹   ENSRNOP00000105100
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl554,113,078 - 54,126,074 (-)Ensembl
RefSeq Acc Id: XM_006238003   ⟹   XP_006238065
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8554,113,073 - 54,123,151 (-)NCBI
mRatBN7.2549,316,784 - 49,326,883 (-)NCBI
Rnor_6.0550,210,303 - 50,220,838 (-)NCBI
Rnor_5.0554,779,257 - 54,790,497 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063288522   ⟹   XP_063144592
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8554,113,073 - 54,132,787 (-)NCBI
RefSeq Acc Id: XM_575796   ⟹   XP_575796
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8554,113,073 - 54,132,787 (-)NCBI
mRatBN7.2549,316,784 - 49,329,164 (-)NCBI
Rnor_6.0550,210,303 - 50,221,560 (-)NCBI
Rnor_5.0554,779,257 - 54,790,497 (-)NCBI
RGSC_v3.4551,367,429 - 51,377,546 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs XP_006238065 (Get FASTA)   NCBI Sequence Viewer  
  XP_063144592 (Get FASTA)   NCBI Sequence Viewer  
  XP_575796 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL98600 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012164
  ENSRNOP00000012164.5
  ENSRNOP00000105100.1
RefSeq Acc Id: XP_575796   ⟸   XM_575796
- Peptide Label: isoform X1
- UniProtKB: D3ZAP6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006238065   ⟸   XM_006238003
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000012164   ⟸   ENSRNOT00000012164
RefSeq Acc Id: XP_063144592   ⟸   XM_063288522
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000105100   ⟸   ENSRNOT00000144574

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZAP6-F1-model_v2 AlphaFold D3ZAP6 1-328 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693631
Promoter ID:EPDNEW_R4146
Type:multiple initiation site
Name:RGD1563056_1
Description:similar to hypothetical protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0550,221,148 - 50,221,208EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1563056 AgrOrtholog
BioCyc Gene G2FUF-41652 BioCyc
Ensembl Genes ENSRNOG00000009178 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012164 ENTREZGENE
  ENSRNOT00000012164.8 UniProtKB/TrEMBL
  ENSRNOT00000144574.1 UniProtKB/TrEMBL
InterPro C6orf163 UniProtKB/TrEMBL
NCBI Gene 500434 ENTREZGENE
PANTHER PTHR34645 UniProtKB/TrEMBL
  SIMILAR TO HYPOTHETICAL PROTEIN UniProtKB/TrEMBL
PhenoGen C5h6orf163 PhenoGen
RatGTEx ENSRNOG00000009178 RatGTEx
UniProt A0ABK0LN01_RAT UniProtKB/TrEMBL
  D3ZAP6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-02 C5h6orf163  similar to human chromosome 6 open reading frame 163  RGD1563056  similar to hypothetical protein  Name and Symbol changed 629549 APPROVED
2008-04-30 RGD1563056  similar to hypothetical protein   RGD1563056_predicted  similar to hypothetical protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1563056_predicted  similar to hypothetical protein (predicted)  LOC500434  similar to hypothetical protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500434  similar to hypothetical protein      Symbol and Name status set to provisional 70820 PROVISIONAL