Ikzf1 (IKAROS family zinc finger 1) - Rat Genome Database

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Pathways
Gene: Ikzf1 (IKAROS family zinc finger 1) Rattus norvegicus
Analyze
Symbol: Ikzf1
Name: IKAROS family zinc finger 1
RGD ID: 1562979
Description: Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; identical protein binding activity; and poly-pyrimidine tract binding activity. Predicted to be involved in erythrocyte differentiation; lymphocyte differentiation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including hematopoietic or lymphoid organ development; lymphocyte differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus and pericentric heterochromatin. Predicted to be part of protein-DNA complex. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; colorectal cancer; and common variable immunodeficiency 13. Orthologous to human IKZF1 (IKAROS family zinc finger 1); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DNA-binding protein Ikaros; LOC305501; RGD1562979; similar to DNA-binding protein Ikaros form 1 - mouse
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81490,468,696 - 90,556,522 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1490,469,172 - 90,557,574 (+)EnsemblGRCr8
mRatBN7.21486,255,065 - 86,340,839 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1486,255,065 - 86,342,416 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1490,660,495 - 90,746,740 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01491,905,260 - 91,991,074 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01488,372,438 - 88,458,707 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01491,782,281 - 91,867,828 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1491,782,354 - 91,867,424 (+)Ensemblrn6Rnor6.0
Rnor_5.01491,567,474 - 91,652,828 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41492,560,200 - 92,657,336 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1485,257,476 - 85,342,328 (+)NCBICelera
Cytogenetic Map14q21NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4,5,6,7-TETRABROMOBENZOTRIAZOLE  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
8-Br-cAMP  (ISO)
acetamide  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
buta-1,3-diene  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
chloroprene  (ISO)
clofibrate  (EXP)
Cuprizon  (EXP)
deguelin  (ISO)
dexamethasone  (ISO)
dimethylarsinic acid  (ISO)
diquat  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
gardiquimod  (ISO)
gentamycin  (EXP)
Indeno[1,2,3-cd]pyrene  (ISO)
indole-3-methanol  (EXP)
L-ascorbic acid  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
permethrin  (EXP)
picoxystrobin  (ISO)
pomalidomide  (ISO)
protein kinase inhibitor  (ISO)
pyrimidifen  (ISO)
rotenone  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
tamibarotene  (ISO)
tebufenpyrad  (ISO)
testosterone  (EXP)
thifluzamide  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Long-range epigenetic silencing associates with deregulation of Ikaros targets in colorectal cancer cells. Javierre BM, etal., Mol Cancer Res. 2011 Aug;9(8):1139-51. doi: 10.1158/1541-7786.MCR-10-0515. Epub 2011 Jul 7.
3. Methylation and Gene Expression of BCAT1 and IKZF1 in Colorectal Cancer Tissues. Jedi M, etal., Clin Med Insights Oncol. 2018 May 10;12:1179554918775064. doi: 10.1177/1179554918775064. eCollection 2018.
4. Prognostic value of genetic alterations in children with first bone marrow relapse of childhood B-cell precursor acute lymphoblastic leukemia. Krentz S, etal., Leukemia. 2013 Feb;27(2):295-304. doi: 10.1038/leu.2012.155. Epub 2012 Jun 13.
5. Detection of Colorectal Cancer in Circulating Cell-Free DNA by Methylated CpG Tandem Amplification and Sequencing. Li J, etal., Clin Chem. 2019 Jul;65(7):916-926. doi: 10.1373/clinchem.2019.301804. Epub 2019 Apr 22.
6. Disease risk factors identified through shared genetic architecture and electronic medical records. Li L, etal., Sci Transl Med. 2014 Apr 30;6(234):234ra57. doi: 10.1126/scitranslmed.3007191.
7. Relationship between post-surgery detection of methylated circulating tumor DNA with risk of residual disease and recurrence-free survival. Murray DH, etal., J Cancer Res Clin Oncol. 2018 Sep;144(9):1741-1750. doi: 10.1007/s00432-018-2701-x. Epub 2018 Jul 10.
8. Evaluation of Circulating Tumor DNA for Methylated BCAT1 and IKZF1 to Detect Recurrence of Stage II/Stage III Colorectal Cancer (CRC). Musher BL, etal., Cancer Epidemiol Biomarkers Prev. 2020 Dec;29(12):2702-2709. doi: 10.1158/1055-9965.EPI-20-0574. Epub 2020 Sep 21.
9. A two-gene blood test for methylated DNA sensitive for colorectal cancer. Pedersen SK, etal., PLoS One. 2015 Apr 30;10(4):e0125041. doi: 10.1371/journal.pone.0125041. eCollection 2015.
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Evaluation of newly identified Ikaros family zinc finger 1 loci in colorectal cancer. Sharma B, etal., J Cancer Res Ther. 2021 Jan-Mar;17(1):46-50. doi: 10.4103/jcrt.JCRT_844_20.
13. Genomic signatures reveal DNA damage response deficiency in colorectal cancer brain metastases. Sun J, etal., Nat Commun. 2019 Jul 18;10(1):3190. doi: 10.1038/s41467-019-10987-3.
14. Circulating epigenetic biomarkers for detection of recurrent colorectal cancer. Symonds EL, etal., Cancer. 2020 Apr 1;126(7):1460-1469. doi: 10.1002/cncr.32695. Epub 2020 Jan 7.
15. Circulating tumour DNA for monitoring colorectal cancer-a prospective cohort study to assess relationship to tissue methylation, cancer characteristics and surgical resection. Symonds EL, etal., Clin Epigenetics. 2018 May 16;10:63. doi: 10.1186/s13148-018-0500-5. eCollection 2018.
16. A cross-sectional study comparing a blood test for methylated BCAT1 and IKZF1 tumor-derived DNA with CEA for detection of recurrent colorectal cancer. Young GP, etal., Cancer Med. 2016 Oct;5(10):2763-2772. doi: 10.1002/cam4.868. Epub 2016 Oct 11.
17. Evaluation of a panel of tumor-specific differentially-methylated DNA regions in IRF4, IKZF1 and BCAT1 for blood-based detection of colorectal cancer. Young GP, etal., Clin Epigenetics. 2021 Jan 21;13(1):14. doi: 10.1186/s13148-020-00999-y.
18. Inhibitory effects of transcription factor Ikaros on the expression of liver cancer stem cell marker CD133 in hepatocellular carcinoma. Zhang L, etal., Oncotarget. 2014 Nov 15;5(21):10621-35. doi: 10.18632/oncotarget.2524.
19. Ikaros is heterogeneously expressed in lung adenocarcinoma and is involved in its progression. Zhao W, etal., J Int Med Res. 2020 Aug;48(8):300060520945860. doi: 10.1177/0300060520945860.
Additional References at PubMed
PMID:7923373   PMID:7969165   PMID:9560339   PMID:10218586   PMID:10366784   PMID:11805317   PMID:12406904   PMID:12617992   PMID:15491138   PMID:15767674   PMID:15841184   PMID:16467156  
PMID:17934067   PMID:18804520   PMID:18940586   PMID:21245044   PMID:21548011   PMID:22106042   PMID:22301782   PMID:23071339   PMID:25654255  


Genomics

Comparative Map Data
Ikzf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81490,468,696 - 90,556,522 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1490,469,172 - 90,557,574 (+)EnsemblGRCr8
mRatBN7.21486,255,065 - 86,340,839 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1486,255,065 - 86,342,416 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1490,660,495 - 90,746,740 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01491,905,260 - 91,991,074 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01488,372,438 - 88,458,707 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01491,782,281 - 91,867,828 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1491,782,354 - 91,867,424 (+)Ensemblrn6Rnor6.0
Rnor_5.01491,567,474 - 91,652,828 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41492,560,200 - 92,657,336 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1485,257,476 - 85,342,328 (+)NCBICelera
Cytogenetic Map14q21NCBI
IKZF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38750,303,455 - 50,405,101 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl750,303,412 - 50,405,101 (+)Ensemblhg38GRCh38
GRCh37750,343,660 - 50,472,799 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36750,411,725 - 50,440,293 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34750,218,438 - 50,244,768NCBI
Celera750,439,276 - 50,537,765 (+)NCBICelera
Cytogenetic Map7p12.2NCBI
HuRef750,294,198 - 50,322,765 (+)NCBIHuRef
HuRef750,224,730 - 50,247,709 (+)NCBIHuRef
CHM1_1750,446,524 - 50,475,092 (+)NCBICHM1_1
CHM1_1750,346,669 - 50,369,648 (+)NCBICHM1_1
T2T-CHM13v2.0750,464,429 - 50,566,317 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2750,381,631 - 50,478,870 (+)NCBI
Ikzf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391111,634,970 - 11,722,930 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1111,634,980 - 11,722,926 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381111,684,962 - 11,772,930 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1111,685,003 - 11,772,926 (+)Ensemblmm10GRCm38
MGSCv371111,586,216 - 11,672,929 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361111,586,216 - 11,672,929 (+)NCBIMGSCv36mm8
Celera1112,146,027 - 12,232,163 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map117.02NCBI
Ikzf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554563,635,380 - 3,721,791 (-)Ensembl
ChiLan1.0NW_0049554563,617,988 - 3,721,791 (-)NCBIChiLan1.0ChiLan1.0
IKZF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2655,183,057 - 55,284,060 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17103,507,780 - 103,608,783 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0750,946,817 - 51,047,168 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1751,191,691 - 51,291,245 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl751,191,685 - 51,291,245 (+)EnsemblpanPan2panpan1.1
IKZF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1181,661,851 - 1,750,987 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl181,661,690 - 1,770,768 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha181,653,280 - 1,744,958 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0181,719,409 - 1,812,327 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl181,719,944 - 1,812,326 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1181,693,685 - 1,785,344 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0181,690,232 - 1,781,782 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0181,826,862 - 1,918,574 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ikzf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118104,966,894 - 105,063,530 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366861,462,145 - 1,556,451 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366861,459,582 - 1,556,478 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IKZF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9136,372,725 - 136,464,940 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.19136,372,202 - 136,464,942 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29150,041,447 - 150,045,891 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IKZF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,398,902 - 8,500,431 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl218,402,719 - 8,484,723 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606213,778,793 - 13,883,296 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ikzf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247403,785,209 - 3,875,841 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247403,785,342 - 3,875,892 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Ikzf1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11180,610,332 - 80,694,075 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ikzf1
734 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:75
Count of miRNA genes:54
Interacting mature miRNAs:64
Transcripts:ENSRNOT00000005902
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631213Bw60Body weight QTL604.51retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)1484164970100078267Rat
1582236Gluco22Glucose level QTL 223.30.0164blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
9590294Uminl4Urine mineral level QTL 45.660.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)1459848686104848686Rat
2300197Scl59Serum cholesterol level QTL 59blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)1477914838104348525Rat
631523Pia13Pristane induced arthritis QTL 133.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1433424686102238540Rat
1582259Gluco23Glucose level QTL 233.10.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1474255551109089856Rat
1582197Gluco27Glucose level QTL 273.40.0006blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)147764007196755654Rat
634328Hc5Hypercalciuria QTL 52.3urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1462398852107398852Rat
1582250Gluco26Glucose level QTL 263.30.0009blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1477640071100078267Rat
2317879Alcrsp27Alcohol response QTL 273.30.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1460854936105854936Rat
1641900Alcrsp11Alcohol response QTL 11alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)1474255551109089856Rat
4889951Bss92Bone structure and strength QTL 923.9tibia area (VT:1000281)tibia-fibula cortical bone total cross-sectional area (CMO:0001721)1486271332100078267Rat
631839Niddm37Non-insulin dependent diabetes mellitus QTL 373.37blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1411334716100078267Rat
1582255Gluco29Glucose level QTL 293.10.0025blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)147764007196755654Rat
9589034Epfw11Epididymal fat weight QTL 1160.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1459848686104848686Rat
1582209Gluco20Glucose level QTL 203.80.0005blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)147764007196755654Rat
1300136Rf22Renal function QTL 223.9renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)144261625899224555Rat
1549834Scl45Serum cholesterol level QTL 455.8blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)146592028399224555Rat

Markers in Region
D14Uia3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21486,258,403 - 86,258,598 (+)MAPPERmRatBN7.2
Rnor_6.01491,785,693 - 91,785,887NCBIRnor6.0
Rnor_5.01491,570,812 - 91,571,006UniSTSRnor5.0
RGSC_v3.41492,563,538 - 92,563,733RGDRGSC3.4
RGSC_v3.41492,563,539 - 92,563,733UniSTSRGSC3.4
Celera1485,260,815 - 85,261,009UniSTS
RGSC_v3.11492,582,683 - 92,582,878RGD
Cytogenetic Map14q21UniSTS
RH137594  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21486,287,429 - 86,287,625 (+)MAPPERmRatBN7.2
Rnor_6.01491,814,590 - 91,814,785NCBIRnor6.0
Rnor_5.01491,599,505 - 91,599,700UniSTSRnor5.0
RGSC_v3.41492,603,718 - 92,603,913UniSTSRGSC3.4
Celera1485,289,605 - 85,289,800UniSTS
Cytogenetic Map14q21UniSTS
RH139754  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21486,342,476 - 86,342,684 (+)MAPPERmRatBN7.2
Rnor_6.01491,869,464 - 91,869,671NCBIRnor6.0
Rnor_5.01491,654,287 - 91,654,494UniSTSRnor5.0
RGSC_v3.41492,659,376 - 92,659,583UniSTSRGSC3.4
Celera1485,344,368 - 85,344,575UniSTS
RH 3.4 Map14634.49UniSTS
Cytogenetic Map14q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 92 59 6 356 192 11 140 81 92 31 13 13

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001436949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006251497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770314 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770315 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770316 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063273234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC115644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000005902   ⟹   ENSRNOP00000005902
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1486,255,065 - 86,340,437 (+)Ensembl
Rnor_6.0 Ensembl1491,782,354 - 91,867,424 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000080753   ⟹   ENSRNOP00000069446
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1490,469,172 - 90,557,574 (+)Ensembl
mRatBN7.2 Ensembl1486,255,625 - 86,340,437 (+)Ensembl
Rnor_6.0 Ensembl1491,783,514 - 91,867,098 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000094159   ⟹   ENSRNOP00000082686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1486,262,134 - 86,340,437 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097538   ⟹   ENSRNOP00000086084
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1490,473,639 - 90,556,521 (+)Ensembl
mRatBN7.2 Ensembl1486,255,065 - 86,342,416 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000113896   ⟹   ENSRNOP00000088172
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1486,256,227 - 86,340,437 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000129081   ⟹   ENSRNOP00000106731
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1490,469,373 - 90,557,574 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000129247   ⟹   ENSRNOP00000111933
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1490,473,719 - 90,557,334 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000133484   ⟹   ENSRNOP00000105080
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1490,482,833 - 90,557,574 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000150446   ⟹   ENSRNOP00000099253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1490,469,373 - 90,557,574 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000156187   ⟹   ENSRNOP00000112283
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1490,473,639 - 90,556,521 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000161801   ⟹   ENSRNOP00000112759
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1490,469,959 - 90,556,521 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000172161   ⟹   ENSRNOP00000101805
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1490,469,212 - 90,557,574 (+)Ensembl
RefSeq Acc Id: NM_001107237   ⟹   NP_001100707
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,468,696 - 90,554,061 (+)NCBI
mRatBN7.21486,255,065 - 86,340,437 (+)NCBI
Rnor_6.01491,782,354 - 91,867,424 (+)NCBI
Rnor_5.01491,567,474 - 91,652,828 (+)NCBI
RGSC_v3.41492,560,200 - 92,657,336 (+)RGD
Celera1485,257,476 - 85,342,328 (+)RGD
Sequence:
RefSeq Acc Id: XM_006251491   ⟹   XP_006251553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,469,444 - 90,556,522 (+)NCBI
mRatBN7.21486,255,877 - 86,340,219 (+)NCBI
Rnor_6.01491,783,732 - 91,867,828 (+)NCBI
Rnor_5.01491,567,474 - 91,652,828 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006251492   ⟹   XP_006251554
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,470,209 - 90,556,522 (+)NCBI
mRatBN7.21486,256,577 - 86,340,839 (+)NCBI
Rnor_6.01491,783,836 - 91,867,828 (+)NCBI
Rnor_5.01491,567,474 - 91,652,828 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006251494   ⟹   XP_006251556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,469,199 - 90,556,522 (+)NCBI
mRatBN7.21486,255,727 - 86,340,839 (+)NCBI
Rnor_6.01491,783,039 - 91,867,828 (+)NCBI
Rnor_5.01491,567,474 - 91,652,828 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770313   ⟹   XP_008768535
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,469,299 - 90,556,522 (+)NCBI
mRatBN7.21486,255,726 - 86,340,839 (+)NCBI
Rnor_6.01491,783,038 - 91,867,828 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770314   ⟹   XP_008768536
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,469,303 - 90,556,522 (+)NCBI
mRatBN7.21486,255,726 - 86,340,839 (+)NCBI
Rnor_6.01491,783,038 - 91,867,828 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770315   ⟹   XP_008768537
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,469,309 - 90,556,522 (+)NCBI
mRatBN7.21486,255,726 - 86,340,839 (+)NCBI
Rnor_6.01491,783,039 - 91,867,828 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770316   ⟹   XP_008768538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,469,296 - 90,556,522 (+)NCBI
mRatBN7.21486,255,726 - 86,340,839 (+)NCBI
Rnor_6.01491,783,038 - 91,867,828 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770318   ⟹   XP_008768540
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,469,291 - 90,556,522 (+)NCBI
mRatBN7.21486,255,725 - 86,340,839 (+)NCBI
Rnor_6.01491,783,037 - 91,867,828 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039092062   ⟹   XP_038947990
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,469,302 - 90,556,522 (+)NCBI
mRatBN7.21486,255,726 - 86,340,839 (+)NCBI
RefSeq Acc Id: XM_039092063   ⟹   XP_038947991
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,469,288 - 90,556,522 (+)NCBI
mRatBN7.21486,255,725 - 86,340,839 (+)NCBI
RefSeq Acc Id: XM_039092065   ⟹   XP_038947993
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,469,295 - 90,556,522 (+)NCBI
mRatBN7.21486,255,726 - 86,340,839 (+)NCBI
RefSeq Acc Id: XM_039092066   ⟹   XP_038947994
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,469,252 - 90,556,522 (+)NCBI
mRatBN7.21486,255,725 - 86,340,839 (+)NCBI
RefSeq Acc Id: XM_063273233   ⟹   XP_063129303
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,469,295 - 90,556,522 (+)NCBI
RefSeq Acc Id: XM_063273234   ⟹   XP_063129304
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81490,469,285 - 90,556,522 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001100707 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423877 (Get FASTA)   NCBI Sequence Viewer  
  NP_001423878 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251553 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251554 (Get FASTA)   NCBI Sequence Viewer  
  XP_006251556 (Get FASTA)   NCBI Sequence Viewer  
  XP_008768535 (Get FASTA)   NCBI Sequence Viewer  
  XP_008768536 (Get FASTA)   NCBI Sequence Viewer  
  XP_008768537 (Get FASTA)   NCBI Sequence Viewer  
  XP_008768538 (Get FASTA)   NCBI Sequence Viewer  
  XP_008768540 (Get FASTA)   NCBI Sequence Viewer  
  XP_038947990 (Get FASTA)   NCBI Sequence Viewer  
  XP_038947991 (Get FASTA)   NCBI Sequence Viewer  
  XP_038947993 (Get FASTA)   NCBI Sequence Viewer  
  XP_038947994 (Get FASTA)   NCBI Sequence Viewer  
  XP_063129303 (Get FASTA)   NCBI Sequence Viewer  
  XP_063129304 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL76057 (Get FASTA)   NCBI Sequence Viewer  
  EDL76058 (Get FASTA)   NCBI Sequence Viewer  
  EDL76059 (Get FASTA)   NCBI Sequence Viewer  
  EDL76060 (Get FASTA)   NCBI Sequence Viewer  
  EDL76061 (Get FASTA)   NCBI Sequence Viewer  
  EDL76062 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000069446
  ENSRNOP00000069446.2
  ENSRNOP00000086084
  ENSRNOP00000086084.1
  ENSRNOP00000099253.1
  ENSRNOP00000101805.1
  ENSRNOP00000105080
  ENSRNOP00000105080.1
  ENSRNOP00000106731
  ENSRNOP00000106731.1
  ENSRNOP00000111933
  ENSRNOP00000111933.1
  ENSRNOP00000112283.1
  ENSRNOP00000112759
  ENSRNOP00000112759.1
RefSeq Acc Id: NP_001100707   ⟸   NM_001107237
- UniProtKB: A6KJA9 (UniProtKB/TrEMBL),   A0A8I5ZVE4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251556   ⟸   XM_006251494
- Peptide Label: isoform X1
- UniProtKB: A0A0G2JVD9 (UniProtKB/TrEMBL),   D4A9W4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251553   ⟸   XM_006251491
- Peptide Label: isoform X5
- UniProtKB: A6KJA7 (UniProtKB/TrEMBL),   D4A9W4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006251554   ⟸   XM_006251492
- Peptide Label: isoform X5
- UniProtKB: A6KJA7 (UniProtKB/TrEMBL),   D4A9W4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768536   ⟸   XM_008770314
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A4M7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768535   ⟸   XM_008770313
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A5Y7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768538   ⟸   XM_008770316
- Peptide Label: isoform X8
- UniProtKB: A0A8I6A4M7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768537   ⟸   XM_008770315
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_008768540   ⟸   XM_008770318
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZVE4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000069446   ⟸   ENSRNOT00000080753
Ensembl Acc Id: ENSRNOP00000005902   ⟸   ENSRNOT00000005902
RefSeq Acc Id: XP_038947991   ⟸   XM_039092063
- Peptide Label: isoform X6
- UniProtKB: A0A8I6A5Y7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947994   ⟸   XM_039092066
- Peptide Label: isoform X12
- UniProtKB: A0A8I5ZVE4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947990   ⟸   XM_039092062
- Peptide Label: isoform X2
- UniProtKB: D4A9W4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038947993   ⟸   XM_039092065
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZVE4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000082686   ⟸   ENSRNOT00000094159
Ensembl Acc Id: ENSRNOP00000088172   ⟸   ENSRNOT00000113896
Ensembl Acc Id: ENSRNOP00000086084   ⟸   ENSRNOT00000097538
RefSeq Acc Id: XP_063129304   ⟸   XM_063273234
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063129303   ⟸   XM_063273233
- Peptide Label: isoform X11
- UniProtKB: A0A8I5ZVE4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000101805   ⟸   ENSRNOT00000172161
Ensembl Acc Id: ENSRNOP00000105080   ⟸   ENSRNOT00000133484
Ensembl Acc Id: ENSRNOP00000106731   ⟸   ENSRNOT00000129081
Ensembl Acc Id: ENSRNOP00000099253   ⟸   ENSRNOT00000150446
Ensembl Acc Id: ENSRNOP00000112759   ⟸   ENSRNOT00000161801
Ensembl Acc Id: ENSRNOP00000111933   ⟸   ENSRNOT00000129247
Ensembl Acc Id: ENSRNOP00000112283   ⟸   ENSRNOT00000156187
Protein Domains
C2H2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JVD9-F1-model_v2 AlphaFold A0A0G2JVD9 1-514 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699494
Promoter ID:EPDNEW_R10016
Type:initiation region
Name:Ikzf1_1
Description:IKAROS family zinc finger 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01491,783,570 - 91,783,630EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562979 AgrOrtholog
BioCyc Gene G2FUF-14993 BioCyc
Ensembl Genes ENSRNOG00000004444 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000080753 ENTREZGENE
  ENSRNOT00000080753.3 UniProtKB/TrEMBL
  ENSRNOT00000097538 ENTREZGENE
  ENSRNOT00000097538.2 UniProtKB/TrEMBL
  ENSRNOT00000129081 ENTREZGENE
  ENSRNOT00000129081.1 UniProtKB/TrEMBL
  ENSRNOT00000129247 ENTREZGENE
  ENSRNOT00000129247.1 UniProtKB/TrEMBL
  ENSRNOT00000133484 ENTREZGENE
  ENSRNOT00000133484.1 UniProtKB/TrEMBL
  ENSRNOT00000150446.1 UniProtKB/TrEMBL
  ENSRNOT00000156187.1 UniProtKB/TrEMBL
  ENSRNOT00000161801 ENTREZGENE
  ENSRNOT00000161801.1 UniProtKB/TrEMBL
  ENSRNOT00000172161.1 UniProtKB/TrEMBL
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
InterPro Ikaros_C2H2-ZF UniProtKB/TrEMBL
  Znf_C2H2/integrase_DNA-bd UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
KEGG Report rno:305501 UniProtKB/TrEMBL
NCBI Gene 305501 ENTREZGENE
PANTHER DNA-BINDING PROTEIN IKAROS UniProtKB/TrEMBL
  ZINC FINGER PROTEIN UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
PhenoGen Ikzf1 PhenoGen
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004444 RatGTEx
SMART ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/TrEMBL
UniProt A0A0G2JVD9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZVE4 ENTREZGENE
  A0A8I6A4M7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A5Y7 ENTREZGENE
  A0ABK0L4K5_RAT UniProtKB/TrEMBL
  A0ABK0LC91_RAT UniProtKB/TrEMBL
  A0ABK0LHN9_RAT UniProtKB/TrEMBL
  A0ABK0LWM4_RAT UniProtKB/TrEMBL
  A0ABK0M318_RAT UniProtKB/TrEMBL
  A0ABK0M862_RAT UniProtKB/TrEMBL
  A0ABK0MA34_RAT UniProtKB/TrEMBL
  A6KJA7 ENTREZGENE, UniProtKB/TrEMBL
  A6KJA9 ENTREZGENE, UniProtKB/TrEMBL
  D4A9W4 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-11-06 Ikzf1  IKAROS family zinc finger 1  RGD1562979  similar to DNA-binding protein Ikaros form 1 - mouse   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1562979  similar to DNA-binding protein Ikaros form 1 - mouse   RGD1562979_predicted  similar to DNA-binding protein Ikaros form 1 - mouse (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1562979_predicted  similar to DNA-binding protein Ikaros form 1 - mouse (predicted)  LOC305501  similar to DNA-binding protein Ikaros form 1 - mouse  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC305501  similar to DNA-binding protein Ikaros form 1 - mouse      Symbol and Name status set to provisional 70820 PROVISIONAL