Icoslg (inducible T-cell co-stimulator ligand) - Rat Genome Database

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Gene: Icoslg (inducible T-cell co-stimulator ligand) Rattus norvegicus
Analyze
Symbol: Icoslg
Name: inducible T-cell co-stimulator ligand
RGD ID: 1562791
Description: Predicted to enable identical protein binding activity and receptor ligand activity. Predicted to be involved in T cell receptor signaling pathway and positive regulation of interleukin-4 production. Predicted to act upstream of or within T follicular helper cell differentiation. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in immunodeficiency 119. Orthologous to human ICOSLG (inducible T cell costimulator ligand); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: icos ligand; Icosl; LOC499415; RGD1562791; similar to B7-like protein GL50-B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82010,600,078 - 10,610,385 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2010,600,078 - 10,610,365 (-)EnsemblGRCr8
mRatBN7.22010,600,420 - 10,610,718 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2010,600,420 - 10,610,703 (-)EnsemblmRatBN7.2
Rnor_6.02011,330,000 - 11,340,307 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2011,329,992 - 11,340,296 (-)Ensemblrn6Rnor6.0
Rnor_5.02013,500,200 - 13,510,518 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42010,930,797 - 10,954,666 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2012,106,187 - 12,116,495 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aripiprazole  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
Azoxymethane  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
carbon nanotube  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dimethylselenide  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
gallic acid  (ISO)
gentamycin  (EXP)
hydroxyl  (ISO)
indometacin  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
methotrexate  (ISO)
N-Nitrosopyrrolidine  (ISO)
nitrates  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP)
tetraphene  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP)
urethane  (ISO)
valproic acid  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10657606   PMID:10760791   PMID:11343123   PMID:16951355   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Icoslg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82010,600,078 - 10,610,385 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2010,600,078 - 10,610,365 (-)EnsemblGRCr8
mRatBN7.22010,600,420 - 10,610,718 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2010,600,420 - 10,610,703 (-)EnsemblmRatBN7.2
Rnor_6.02011,330,000 - 11,340,307 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2011,329,992 - 11,340,296 (-)Ensemblrn6Rnor6.0
Rnor_5.02013,500,200 - 13,510,518 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42010,930,797 - 10,954,666 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2012,106,187 - 12,116,495 (-)NCBICelera
Cytogenetic Map20p12NCBI
ICOSLG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382144,216,981 - 44,240,943 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2144,215,382 - 44,241,446 (-)Ensemblhg38GRCh38
GRCh372145,642,874 - 45,660,826 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362144,471,149 - 44,485,262 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342144,471,151 - 44,485,262NCBI
Celera2130,751,996 - 30,766,092 (-)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2131,016,759 - 31,030,941 (-)NCBIHuRef
CHM1_12145,207,363 - 45,221,476 (-)NCBICHM1_1
T2T-CHM13v2.02142,571,002 - 42,595,008 (-)NCBIT2T-CHM13v2.0
Icosl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391077,904,921 - 77,915,359 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1077,905,136 - 77,919,747 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381078,069,368 - 78,079,525 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1078,069,302 - 78,083,913 (+)Ensemblmm10GRCm38
MGSCv371077,532,113 - 77,542,270 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361077,472,497 - 77,482,654 (+)NCBIMGSCv36mm8
Celera1079,108,390 - 79,118,547 (+)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Icoslg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540741,189,974 - 41,198,254 (+)Ensembl
ChiLan1.0NW_00495540741,190,875 - 41,197,521 (+)NCBIChiLan1.0ChiLan1.0
ICOSLG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22240,221,886 - 40,249,640 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12135,071,404 - 35,099,737 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02130,474,655 - 30,499,302 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12143,770,310 - 43,793,410 (-)NCBIPanPan1.1PanPan1.1panPan2
ICOSLG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13138,084,861 - 38,094,743 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3137,242,305 - 37,252,241 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03137,632,500 - 37,642,445 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3137,632,501 - 37,642,512 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13137,499,628 - 37,509,566 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03137,483,631 - 37,493,563 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03137,978,199 - 37,988,166 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Icoslg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497137,294,671 - 37,303,213 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936500164,603 - 173,155 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936500164,659 - 173,144 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ICOSLG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.113207,106,202 - 207,115,886 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213216,984,895 - 216,994,580 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ICOSLG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1287,974,651 - 87,986,867 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl287,973,786 - 87,986,639 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605416,086,384 - 16,100,434 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Icoslg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474529,880,992 - 29,888,717 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474529,880,943 - 29,888,635 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Icoslg
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1181,355,978 - 1,365,544 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Icoslg
79 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:66
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000038547
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)20418947649189476Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20126925056Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20133724594Rat
7387283Uae44Urinary albumin excretion QTL 440.1712urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)20126128279Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804392029865039Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600300Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20153308346533083Rat
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124164241Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20134066551Rat
631265Iresp1Immunoglobin response QTL18.3blood anti-double stranded DNA antibody amount (VT:0004762)serum anti-DNA antibody level (CMO:0001533)20904109911115921Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129193376Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20127341128Rat
1598870Bp289Blood pressure QTL 2892.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)20821635953216359Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129193376Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129193376Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129193376Rat
1581577Pur15Proteinuria QTL 154.380.0002urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)20804392015089182Rat
1598858Cm61Cardiac mass QTL 613.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)20821635953216359Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129193376Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20114100378Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127341128Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578510Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600300Rat

Markers in Region
RH130319  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22010,604,957 - 10,605,137 (+)MAPPERmRatBN7.2
Rnor_6.02011,334,538 - 11,334,717NCBIRnor6.0
Rnor_5.02013,504,678 - 13,504,857UniSTSRnor5.0
RGSC_v3.42010,948,981 - 10,949,160UniSTSRGSC3.4
Celera2012,110,724 - 12,110,903UniSTS
RH 3.4 Map20152.84UniSTS
Cytogenetic Map20p12UniSTS
RH130781  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82010,600,201 - 10,600,419 (+)Marker Load Pipeline
mRatBN7.22010,600,543 - 10,600,761 (+)MAPPERmRatBN7.2
Rnor_6.02011,330,124 - 11,330,341NCBIRnor6.0
Rnor_5.02013,500,324 - 13,500,541UniSTSRnor5.0
RGSC_v3.42010,944,567 - 10,944,784UniSTSRGSC3.4
Celera2012,106,311 - 12,106,528UniSTS
RH 3.4 Map20149.1UniSTS
Cytogenetic Map20p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 141 81 92 31 16 16

Sequence


Ensembl Acc Id: ENSRNOT00000038547   ⟹   ENSRNOP00000031382
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2010,600,078 - 10,610,365 (-)Ensembl
mRatBN7.2 Ensembl2010,600,422 - 10,610,703 (-)Ensembl
Rnor_6.0 Ensembl2011,329,992 - 11,340,296 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000097075   ⟹   ENSRNOP00000097373
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2010,604,836 - 10,610,703 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098155   ⟹   ENSRNOP00000089880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2010,604,493 - 10,610,365 (-)Ensembl
mRatBN7.2 Ensembl2010,604,836 - 10,610,703 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099769   ⟹   ENSRNOP00000096883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2010,600,420 - 10,610,703 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104489   ⟹   ENSRNOP00000090239
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2010,604,836 - 10,610,703 (-)Ensembl
RefSeq Acc Id: NM_001427376   ⟹   NP_001414305
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82010,600,078 - 10,610,365 (-)NCBI
RefSeq Acc Id: NM_001427377   ⟹   NP_001414306
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82010,604,490 - 10,610,336 (-)NCBI
RefSeq Acc Id: XM_006256260   ⟹   XP_006256322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82010,600,078 - 10,610,376 (-)NCBI
mRatBN7.22010,600,420 - 10,610,717 (-)NCBI
Rnor_6.02011,330,000 - 11,340,307 (-)NCBI
Rnor_5.02013,500,200 - 13,510,518 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256261   ⟹   XP_006256323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82010,600,078 - 10,610,377 (-)NCBI
mRatBN7.22010,600,420 - 10,610,718 (-)NCBI
Rnor_6.02011,330,000 - 11,340,307 (-)NCBI
Rnor_5.02013,500,200 - 13,510,518 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006256262   ⟹   XP_006256324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82010,600,078 - 10,610,385 (-)NCBI
mRatBN7.22010,600,420 - 10,610,717 (-)NCBI
Rnor_6.02011,330,000 - 11,340,307 (-)NCBI
Rnor_5.02013,500,200 - 13,510,518 (-)NCBI
Sequence:
RefSeq Acc Id: XP_006256324   ⟸   XM_006256262
- Peptide Label: isoform X3
- UniProtKB: F1LVL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256323   ⟸   XM_006256261
- Peptide Label: isoform X2
- UniProtKB: F1LVL2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256322   ⟸   XM_006256260
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GLT3 (UniProtKB/TrEMBL),   F1LVL2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000031382   ⟸   ENSRNOT00000038547
Ensembl Acc Id: ENSRNOP00000090239   ⟸   ENSRNOT00000104489
Ensembl Acc Id: ENSRNOP00000096883   ⟸   ENSRNOT00000099769
Ensembl Acc Id: ENSRNOP00000097373   ⟸   ENSRNOT00000097075
Ensembl Acc Id: ENSRNOP00000089880   ⟸   ENSRNOT00000098155
RefSeq Acc Id: NP_001414305   ⟸   NM_001427376
- Peptide Label: isoform 1 precursor
- UniProtKB: F1LVL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001414306   ⟸   NM_001427377
- Peptide Label: isoform 2 precursor

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LVL2-F1-model_v2 AlphaFold F1LVL2 1-307 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701494
Promoter ID:EPDNEW_R12013
Type:multiple initiation site
Name:Icoslg_1
Description:inducible T-cell co-stimulator ligand
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02011,340,258 - 11,340,318EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562791 AgrOrtholog
BioCyc Gene G2FUF-4276 BioCyc
Ensembl Genes ENSRNOG00000023109 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038547 ENTREZGENE
  ENSRNOT00000038547.8 UniProtKB/TrEMBL
  ENSRNOT00000098155 ENTREZGENE
  ENSRNOT00000098155.2 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Ig-like UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  IgSF_BTN/MOG UniProtKB/TrEMBL
NCBI Gene 499415 ENTREZGENE
PANTHER BUTYROPHILIN UniProtKB/TrEMBL
  ICOS LIGAND UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PhenoGen Icoslg PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000023109 RatGTEx
SMART IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A8I6ACR9_RAT UniProtKB/TrEMBL
  A0A8I6GLT3 ENTREZGENE
  F1LVL2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-17 Icoslg  inducible T-cell co-stimulator ligand  Icosl  icos ligand  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-29 Icosl  icos ligand  RGD1562791_predicted  similar to B7-like protein GL50-B (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1562791_predicted  similar to B7-like protein GL50-B (predicted)  LOC499415  similar to B7-like protein GL50-B  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499415  similar to B7-like protein GL50-B      Symbol and Name status set to provisional 70820 PROVISIONAL