Bcor (BCL6 co-repressor) - Rat Genome Database

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Gene: Bcor (BCL6 co-repressor) Rattus norvegicus
Analyze
Symbol: Bcor
Name: BCL6 co-repressor
RGD ID: 1562735
Description: Predicted to enable several functions, including heat shock protein binding activity; histone deacetylase binding activity; and transcription corepressor activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including negative regulation of biomineral tissue development; negative regulation of transcription by RNA polymerase II; and specification of axis polarity. Predicted to act upstream of or within blastocyst hatching. Predicted to be located in nucleoplasm. Predicted to be part of BCOR complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in dental caries; eye disease (multiple); and gastrointestinal system cancer (multiple). Orthologous to human BCOR (BCL6 corepressor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BCL-6 corepressor; Bcl6 interacting corepressor; LOC317346; RGD1562735; similar to BCoR protein (BCL-6 corepressor)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X13,282,431 - 13,402,254 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX13,360,376 - 13,402,254 (+)EnsemblGRCr8
mRatBN7.2X10,609,756 - 10,729,613 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX10,687,732 - 10,729,613 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX10,875,038 - 10,916,895 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X14,371,910 - 14,413,764 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X10,634,826 - 10,676,706 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X11,570,155 - 11,692,022 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX11,648,989 - 11,691,099 (+)Ensemblrn6Rnor6.0
Rnor_5.0X12,366,781 - 12,488,777 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X22,699,778 - 22,820,234 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX11,211,546 - 11,253,981 (+)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acrolein  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
choline  (ISO)
cisplatin  (ISO)
coumarin  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
geldanamycin  (ISO)
gentamycin  (EXP)
L-methionine  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
nitrates  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
piperonyl butoxide  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
resveratrol  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vanadyl sulfate  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
BCOR complex  (ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy. Agardh E, etal., BMC Med. 2015 Aug 6;13:182. doi: 10.1186/s12916-015-0421-5.
2. Inhibition of the transcriptional repressor complex Bcl-6/BCoR induces endothelial sprouting but does not promote tumor growth. Buchberger E, etal., Oncotarget. 2017 Jan 3;8(1):552-564. doi: 10.18632/oncotarget.13477.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Identification of molecular features correlating with tumor immunity in gastric cancer by multi-omics data analysis. He Y and Wang X, Ann Transl Med. 2020 Sep;8(17):1050. doi: 10.21037/atm-20-922.
5. Oculofaciocardiodental and Lenz microphthalmia syndromes result from distinct classes of mutations in BCOR. Ng D, etal., Nat Genet. 2004 Apr;36(4):411-6. Epub 2004 Mar 7.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Comprehensive mutation profiling of mucinous gastric carcinoma. Rokutan H, etal., J Pathol. 2016 Oct;240(2):137-48. doi: 10.1002/path.4761. Epub 2016 Sep 19.
11. Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition. Zeng Z, etal., J Dent Res. 2013 May;92(5):432-7. doi: 10.1177/0022034513481976. Epub 2013 Mar 7.
Additional References at PubMed
PMID:10898795   PMID:12776190   PMID:15878880   PMID:16943429   PMID:17517692   PMID:19578371   PMID:25331958   PMID:27869233  


Genomics

Comparative Map Data
Bcor
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X13,282,431 - 13,402,254 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX13,360,376 - 13,402,254 (+)EnsemblGRCr8
mRatBN7.2X10,609,756 - 10,729,613 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX10,687,732 - 10,729,613 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX10,875,038 - 10,916,895 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X14,371,910 - 14,413,764 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X10,634,826 - 10,676,706 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X11,570,155 - 11,692,022 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX11,648,989 - 11,691,099 (+)Ensemblrn6Rnor6.0
Rnor_5.0X12,366,781 - 12,488,777 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X22,699,778 - 22,820,234 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX11,211,546 - 11,253,981 (+)NCBICelera
Cytogenetic MapXq12NCBI
BCOR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X40,051,246 - 40,177,277 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX40,049,815 - 40,177,329 (-)Ensemblhg38GRCh38
GRCh37X39,910,499 - 40,036,582 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X39,795,561 - 39,846,998 (-)NCBIBuild 36Build 36hg18NCBI36
CeleraX44,049,354 - 44,175,356 (-)NCBICelera
Cytogenetic MapXp11.4NCBI
HuRefX37,648,006 - 37,771,447 (-)NCBIHuRef
CHM1_1X39,942,309 - 40,068,287 (-)NCBICHM1_1
T2T-CHM13v2.0X39,452,491 - 39,578,515 (-)NCBIT2T-CHM13v2.0
Bcor
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X11,902,976 - 12,026,769 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX11,902,979 - 12,026,594 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X12,036,737 - 12,160,516 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX12,036,740 - 12,160,355 (-)Ensemblmm10GRCm38
MGSCv37X11,613,863 - 11,737,481 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X11,193,696 - 11,237,013 (-)NCBIMGSCv36mm8
CeleraX9,733,265 - 9,856,163 (-)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX6.83NCBI
Bcor
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555661,412,540 - 1,457,329 (-)Ensembl
ChiLan1.0NW_0049555661,412,540 - 1,510,339 (-)NCBIChiLan1.0ChiLan1.0
BCOR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X41,696,464 - 41,822,839 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X41,699,844 - 41,826,220 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X32,497,931 - 32,624,307 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X40,203,565 - 40,328,788 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX40,202,235 - 40,249,986 (-)EnsemblpanPan2panpan1.1
BCOR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X34,621,314 - 34,735,502 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX34,621,886 - 34,645,766 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX21,969,928 - 22,084,065 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X34,669,641 - 34,783,826 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX34,668,759 - 34,753,231 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X34,749,439 - 34,863,578 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X34,721,876 - 34,836,005 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X34,764,590 - 34,878,770 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Bcor
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X26,923,332 - 26,971,483 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365026,764,907 - 6,792,916 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365026,764,043 - 6,812,194 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BCOR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX35,768,017 - 35,814,833 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X35,768,013 - 35,891,013 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X39,823,458 - 39,946,360 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BCOR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X37,191,242 - 37,319,966 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX37,192,874 - 37,319,782 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660762,405,573 - 2,532,624 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bcor
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476215,420,596 - 15,465,873 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476215,338,331 - 15,465,683 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Bcor
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X9,268,340 - 9,310,619 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Bcor
797 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:226
Count of miRNA genes:143
Interacting mature miRNAs:174
Transcripts:ENSRNOT00000041003
Prediction methods:Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X400149344939387Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X197044046970440Rat
70166Bp65Blood pressure QTL 655.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X400149314046933Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X811148653111486Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X400149324470521Rat

Markers in Region
DXGot5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X10,618,413 - 10,618,539 (+)MAPPERmRatBN7.2
Rnor_6.0X11,578,842 - 11,578,965NCBIRnor6.0
Rnor_5.0X12,375,422 - 12,375,545UniSTSRnor5.0
RGSC_v3.4X22,708,282 - 22,708,405UniSTSRGSC3.4
RGSC_v3.4X22,708,281 - 22,708,405RGDRGSC3.4
CeleraX11,142,153 - 11,142,278UniSTS
RGSC_v3.1X22,761,600 - 22,761,723RGD
RH 3.4 MapX44.5UniSTS
RH 3.4 MapX44.5RGD
RH 2.0 Map2125.4RGD
Cytogenetic MapXq13UniSTS
RH91894  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X10,685,254 - 10,685,385 (+)MAPPERmRatBN7.2
Rnor_6.0X11,646,512 - 11,646,642NCBIRnor6.0
Rnor_5.0X12,444,190 - 12,444,320UniSTSRnor5.0
RGSC_v3.4X22,775,978 - 22,776,108UniSTSRGSC3.4
CeleraX11,209,073 - 11,209,203UniSTS
Cytogenetic MapXq13UniSTS
AU047974  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X10,635,771 - 10,636,028 (+)MAPPERmRatBN7.2
Rnor_6.0X11,596,186 - 11,596,442NCBIRnor6.0
Rnor_5.0X12,392,766 - 12,393,022UniSTSRnor5.0
RGSC_v3.4X22,725,626 - 22,725,882UniSTSRGSC3.4
CeleraX11,159,497 - 11,159,741UniSTS
Cytogenetic MapXq13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
22 12 82 209 91 90 59 143 59 6 454 265 18 181 100 115 31 33 33

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001191586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280046 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000041003   ⟹   ENSRNOP00000047677
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX10,687,732 - 10,729,613 (+)Ensembl
Rnor_6.0 EnsemblX11,648,989 - 11,691,099 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105188   ⟹   ENSRNOP00000076883
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX10,687,732 - 10,729,613 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116761   ⟹   ENSRNOP00000086890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX10,687,732 - 10,729,613 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120870   ⟹   ENSRNOP00000098479
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX13,360,376 - 13,402,254 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000120871   ⟹   ENSRNOP00000098480
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX13,360,376 - 13,402,254 (+)Ensembl
RefSeq Acc Id: NM_001191586   ⟹   NP_001178515
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X13,360,376 - 13,402,254 (+)NCBI
mRatBN7.2X10,687,732 - 10,729,613 (+)NCBI
Rnor_6.0X11,648,989 - 11,691,099 (+)NCBI
Rnor_5.0X12,366,781 - 12,488,777 (+)NCBI
CeleraX11,211,546 - 11,253,981 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099759   ⟹   XP_038955687
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X13,313,320 - 13,402,254 (+)NCBI
mRatBN7.2X10,640,621 - 10,729,061 (+)NCBI
RefSeq Acc Id: XM_039099760   ⟹   XP_038955688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X13,282,431 - 13,402,254 (+)NCBI
mRatBN7.2X10,609,756 - 10,729,061 (+)NCBI
RefSeq Acc Id: XM_039099761   ⟹   XP_038955689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X13,361,015 - 13,402,254 (+)NCBI
mRatBN7.2X10,688,362 - 10,729,061 (+)NCBI
RefSeq Acc Id: XM_039099762   ⟹   XP_038955690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X13,347,393 - 13,402,254 (+)NCBI
mRatBN7.2X10,674,743 - 10,729,061 (+)NCBI
RefSeq Acc Id: XM_039099763   ⟹   XP_038955691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X13,357,805 - 13,402,254 (+)NCBI
mRatBN7.2X10,685,194 - 10,729,061 (+)NCBI
RefSeq Acc Id: XM_039099764   ⟹   XP_038955692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X13,361,400 - 13,402,254 (+)NCBI
mRatBN7.2X10,688,753 - 10,729,061 (+)NCBI
RefSeq Acc Id: XM_039099765   ⟹   XP_038955693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X13,359,945 - 13,402,254 (+)NCBI
mRatBN7.2X10,687,821 - 10,729,061 (+)NCBI
RefSeq Acc Id: XM_039099766   ⟹   XP_038955694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X13,359,827 - 13,402,254 (+)NCBI
mRatBN7.2X10,687,821 - 10,729,061 (+)NCBI
RefSeq Acc Id: XM_063280045   ⟹   XP_063136115
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X13,359,848 - 13,402,254 (+)NCBI
RefSeq Acc Id: XM_063280046   ⟹   XP_063136116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X13,359,835 - 13,402,254 (+)NCBI
RefSeq Acc Id: XM_063280047   ⟹   XP_063136117
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X13,313,320 - 13,402,254 (+)NCBI
RefSeq Acc Id: XM_063280048   ⟹   XP_063136118
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X13,282,432 - 13,402,254 (+)NCBI
RefSeq Acc Id: XM_063280049   ⟹   XP_063136119
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X13,360,964 - 13,402,254 (+)NCBI
RefSeq Acc Id: NP_001178515   ⟸   NM_001191586
- UniProtKB: D4A2J9 (UniProtKB/TrEMBL),   A0A8I5XVI9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000047677   ⟸   ENSRNOT00000041003
RefSeq Acc Id: XP_038955688   ⟸   XM_039099760
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038955687   ⟸   XM_039099759
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038955690   ⟸   XM_039099762
- Peptide Label: isoform X1
- UniProtKB: D4A2J9 (UniProtKB/TrEMBL),   A0A8I5XVI9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955691   ⟸   XM_039099763
- Peptide Label: isoform X1
- UniProtKB: D4A2J9 (UniProtKB/TrEMBL),   A0A8I5XVI9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955694   ⟸   XM_039099766
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038955693   ⟸   XM_039099765
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A262 (UniProtKB/TrEMBL),   A0A8I5XVI9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955689   ⟸   XM_039099761
- Peptide Label: isoform X1
- UniProtKB: D4A2J9 (UniProtKB/TrEMBL),   A0A8I5XVI9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955692   ⟸   XM_039099764
- Peptide Label: isoform X1
- UniProtKB: D4A2J9 (UniProtKB/TrEMBL),   A0A8I5XVI9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000076883   ⟸   ENSRNOT00000105188
Ensembl Acc Id: ENSRNOP00000086890   ⟸   ENSRNOT00000116761
RefSeq Acc Id: XP_063136118   ⟸   XM_063280048
- Peptide Label: isoform X3
- UniProtKB: A6K007 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136117   ⟸   XM_063280047
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063136116   ⟸   XM_063280046
- Peptide Label: isoform X2
- UniProtKB: A0A8I5XVI9 (UniProtKB/TrEMBL),   A0A8I6A262 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136115   ⟸   XM_063280045
- Peptide Label: isoform X1
- UniProtKB: A0A8I5XVI9 (UniProtKB/TrEMBL),   D4A2J9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136119   ⟸   XM_063280049
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000098479   ⟸   ENSRNOT00000120870
Ensembl Acc Id: ENSRNOP00000098480   ⟸   ENSRNOT00000120871
Protein Domains
BCL-6 corepressor non-ankyrin-repeat   BCL-6 corepressor PCGF1 binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A2J9-F1-model_v2 AlphaFold D4A2J9 1-1757 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701714
Promoter ID:EPDNEW_R12238
Type:multiple initiation site
Name:Bcor_1
Description:BCL6 co-repressor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X11,648,965 - 11,649,025EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562735 AgrOrtholog
BioCyc Gene G2FUF-3054 BioCyc
Ensembl Genes ENSRNOG00000034240 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000120870 ENTREZGENE
  ENSRNOT00000120870.2 UniProtKB/TrEMBL
  ENSRNOT00000120871 ENTREZGENE
  ENSRNOT00000120871.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.20 UniProtKB/TrEMBL
  3.10.260.40 UniProtKB/TrEMBL
InterPro Ankyrin_rpt UniProtKB/TrEMBL
  Ankyrin_rpt-contain_sf UniProtKB/TrEMBL
  BCOR UniProtKB/TrEMBL
  BCOR-like UniProtKB/TrEMBL
  PUFD UniProtKB/TrEMBL
  PUFD_som_sf UniProtKB/TrEMBL
NCBI Gene 317346 ENTREZGENE
PANTHER AGAP007537-PB UniProtKB/TrEMBL
  BCL-6 COREPRESSOR UniProtKB/TrEMBL
Pfam Ank_2 UniProtKB/TrEMBL
  BCOR UniProtKB/TrEMBL
  PUFD UniProtKB/TrEMBL
PhenoGen Bcor PhenoGen
PROSITE ANK_REP_REGION UniProtKB/TrEMBL
  ANK_REPEAT UniProtKB/TrEMBL
RatGTEx ENSRNOG00000034240 RatGTEx
SMART ANK UniProtKB/TrEMBL
Superfamily-SCOP ANK UniProtKB/TrEMBL
UniProt A0A8I5XVI9 ENTREZGENE
  A0A8I6A262 ENTREZGENE
  A0ABK0KW87_RAT UniProtKB/TrEMBL
  A0ABK0LBN1_RAT UniProtKB/TrEMBL
  A6K007 ENTREZGENE, UniProtKB/TrEMBL
  D4A2J9 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-01-05 Bcor  BCL6 co-repressor  Bcor  Bcl6 interacting corepressor   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Bcor  Bcl6 interacting corepressor   Bcor_predicted  Bcl6 interacting corepressor (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-30 Bcor_predicted  Bcl6 interacting corepressor (predicted)  RGD1562735_predicted  similar to BCoR protein (BCL-6 corepressor) (predicted)  Symbol and Name updated 1299863 APPROVED
2006-03-07 RGD1562735_predicted  similar to BCoR protein (BCL-6 corepressor) (predicted)  LOC317346  similar to BCoR protein (BCL-6 corepressor)  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC317346  similar to BCoR protein (BCL-6 corepressor)      Symbol and Name status set to provisional 70820 PROVISIONAL