Pgr15l (G protein-coupled receptor 15-like) - Rat Genome Database

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Gene: Pgr15l (G protein-coupled receptor 15-like) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Pgr15l
Name: G protein-coupled receptor 15-like
RGD ID: 1562685
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be located in membrane and non-motile cilium. Predicted to be active in plasma membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; copper atom.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC296867; RGD1562685; similar to G protein-coupled receptor PGR15L
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X65,994,870 - 66,000,382 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX65,994,870 - 66,000,701 (+)EnsemblGRCr8
mRatBN7.2X61,983,518 - 61,989,030 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX61,983,518 - 61,989,030 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX63,446,276 - 63,451,788 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X66,946,817 - 66,952,329 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X64,509,731 - 64,515,263 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X66,314,416 - 66,319,928 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX66,314,418 - 66,320,145 (+)Ensemblrn6Rnor6.0
Rnor_5.0X67,143,789 - 67,149,301 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X84,756,022 - 84,761,534 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX62,382,643 - 62,388,155 (+)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cilium  (IEA)
membrane  (IEA)
non-motile cilium  (IEA)
plasma membrane  (IBA,IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Pgr15l
12 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:67
Interacting mature miRNAs:70
Transcripts:ENSRNOT00000035405
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
70221Bp56Blood pressure QTL 564.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X6103585667175160Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat


Expression

RNA-SEQ Expression

circulatory system
ectoderm
endocrine system
mesenchyme
mesoderm
musculoskeletal system
nervous system
reproductive system
1 72 8 6 6 1 67 36

Sequence


Ensembl Acc Id: ENSRNOT00000035405   ⟹   ENSRNOP00000034633
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX65,994,870 - 66,000,701 (+)Ensembl
mRatBN7.2 EnsemblX61,983,518 - 61,989,030 (+)Ensembl
Rnor_6.0 EnsemblX66,314,418 - 66,320,145 (+)Ensembl
RefSeq Acc Id: NM_001106583   ⟹   NP_001100053
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X65,994,870 - 66,000,382 (+)NCBI
mRatBN7.2X61,983,518 - 61,989,030 (+)NCBI
Rnor_6.0X66,314,416 - 66,319,928 (+)NCBI
Rnor_5.0X67,143,789 - 67,149,301 (+)NCBI
RGSC_v3.4X84,756,022 - 84,761,534 (+)RGD
CeleraX62,382,643 - 62,388,155 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100053 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL95964 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000034633
  ENSRNOP00000034633.3
RefSeq Acc Id: NP_001100053   ⟸   NM_001106583
- UniProtKB: D3ZQ49 (UniProtKB/TrEMBL),   A6IQ49 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000034633   ⟸   ENSRNOT00000035405
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZQ49-F1-model_v2 AlphaFold D3ZQ49 1-456 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562685 AgrOrtholog
BioCyc Gene G2FUF-2178 BioCyc
Ensembl Genes ENSRNOG00000021547 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000035405 ENTREZGENE
  ENSRNOT00000035405.6 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  NPY_rcpt UniProtKB/TrEMBL
KEGG Report rno:296867 UniProtKB/TrEMBL
NCBI Gene 296867 ENTREZGENE
PANTHER GH23382P UniProtKB/TrEMBL
  NEUROPEPTIDE Y RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/TrEMBL
PhenoGen Pgr15l PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  NRPEPTIDEYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000021547 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6IQ49 ENTREZGENE, UniProtKB/TrEMBL
  D3ZQ49 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-29 Pgr15l  G protein-coupled receptor 15-like  RGD1562685_predicted  similar to G protein-coupled receptor PGR15L (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1562685_predicted  similar to G protein-coupled receptor PGR15L (predicted)  LOC296867  similar to G protein-coupled receptor PGR15L  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC296867  similar to G protein-coupled receptor PGR15L      Symbol and Name status set to provisional 70820 PROVISIONAL