Smyd3 (SET and MYND domain containing 3) - Rat Genome Database

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Gene: Smyd3 (SET and MYND domain containing 3) Rattus norvegicus
Analyze
Symbol: Smyd3
Name: SET and MYND domain containing 3
RGD ID: 1562635
Description: Predicted to enable RNA polymerase II complex binding activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and histone methyltransferase activity. Predicted to be involved in methylation. Predicted to act upstream of or within several processes, including cellular response to dexamethasone stimulus; nucleosome assembly; and regulation of protein phosphorylation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human SMYD3 (SET and MYND domain containing 3); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: histone-lysine N-methyltransferase SMYD3; LOC498295; MGC114517; SET and MYND domain-containing protein 3; similar to SET and MYND domain containing 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81393,241,274 - 93,798,221 (-)NCBIGRCr8
mRatBN7.21390,709,263 - 91,266,209 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1390,709,270 - 91,266,253 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1393,214,478 - 93,771,407 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01394,614,652 - 95,171,578 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01391,792,563 - 92,346,249 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01397,330,120 - 97,807,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013102,581,420 - 102,588,971 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.013102,350,012 - 102,473,942 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41394,643,716 - 95,108,789 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1390,265,163 - 90,818,620 (-)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
2-palmitoylglycerol  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
7,12-dimethyltetraphene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
berberine  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dieldrin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
indometacin  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
MeIQx  (ISO)
methamphetamine  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N-Nitrosopyrrolidine  (ISO)
nickel sulfate  (ISO)
O-methyleugenol  (ISO)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
PhIP  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
titanium dioxide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Black JC, etal., Mol Cell. 2012 Nov 30;48(4):491-507. doi: 10.1016/j.molcel.2012.11.006.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:16805913   PMID:23752591   PMID:25738358   PMID:33144524  


Genomics

Comparative Map Data
Smyd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81393,241,274 - 93,798,221 (-)NCBIGRCr8
mRatBN7.21390,709,263 - 91,266,209 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1390,709,270 - 91,266,253 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1393,214,478 - 93,771,407 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01394,614,652 - 95,171,578 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01391,792,563 - 92,346,249 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01397,330,120 - 97,807,813 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013102,581,420 - 102,588,971 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.013102,350,012 - 102,473,942 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41394,643,716 - 95,108,789 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1390,265,163 - 90,818,620 (-)NCBICelera
Cytogenetic Map13q26NCBI
SMYD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381245,749,347 - 246,507,279 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1245,749,342 - 246,507,312 (-)EnsemblGRCh38hg38GRCh38
GRCh371245,912,649 - 246,670,581 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361243,979,267 - 244,647,334 (-)NCBINCBI36Build 36hg18NCBI36
Build 341242,238,685 - 242,906,752NCBI
Celera1219,204,089 - 219,959,418 (-)NCBICelera
Cytogenetic Map1q44NCBI
HuRef1216,300,241 - 217,057,123 (-)NCBIHuRef
CHM1_11247,184,928 - 247,943,100 (-)NCBICHM1_1
T2T-CHM13v2.01245,170,078 - 245,930,104 (-)NCBIT2T-CHM13v2.0
Smyd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,779,525 - 179,345,618 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1178,779,525 - 179,345,606 (-)EnsemblGRCm39 Ensembl
GRCm381178,951,960 - 179,518,053 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,951,960 - 179,518,041 (-)EnsemblGRCm38mm10GRCm38
MGSCv371180,885,162 - 181,448,134 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361180,791,706 - 181,354,678 (-)NCBIMGSCv36mm8
Celera1186,017,554 - 186,588,962 (-)NCBICelera
Cytogenetic Map1H4NCBI
cM Map183.48NCBI
Smyd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554068,768,588 - 9,417,525 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554068,768,365 - 9,417,612 (-)NCBIChiLan1.0ChiLan1.0
SMYD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v212,624,092 - 3,383,506 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112,841,208 - 3,607,222 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01221,371,348 - 222,125,774 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11226,737,739 - 227,481,309 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1226,737,960 - 227,481,191 (-)Ensemblpanpan1.1panPan2
SMYD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1736,561,080 - 37,250,336 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl736,565,901 - 37,250,578 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha736,041,500 - 36,732,806 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0736,391,898 - 37,082,573 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl736,396,600 - 37,082,534 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1736,231,858 - 36,922,858 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0736,245,479 - 36,930,875 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0736,513,397 - 37,199,813 (-)NCBIUU_Cfam_GSD_1.0
Smyd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934449,528,419 - 50,211,118 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365264,536,142 - 5,218,657 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365264,536,157 - 5,218,883 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMYD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1018,267,189 - 19,019,642 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11018,267,598 - 19,019,520 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21020,923,785 - 21,568,712 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103230910
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12582,794,748 - 83,531,942 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605585,053,359 - 85,234,932 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smyd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477113,149,649 - 13,943,137 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477113,149,547 - 13,943,352 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Smyd3
3574 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:32
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000040829
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1366451204106807694Rat
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134608804691088046Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133124133193395974Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat

Markers in Region
D13Got79  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21390,972,702 - 90,972,828 (-)MAPPERmRatBN7.2
Rnor_6.01396,627,501 - 96,627,626NCBIRnor6.0
Rnor_5.013101,654,006 - 101,654,131UniSTSRnor5.0
RGSC_v3.41394,926,164 - 94,926,290RGDRGSC3.4
RGSC_v3.41394,926,165 - 94,926,290UniSTSRGSC3.4
RGSC_v3.11395,115,101 - 95,115,226RGD
Celera1390,525,340 - 90,525,464UniSTS
RH 3.4 Map13615.3UniSTS
RH 3.4 Map13615.3RGD
RH 2.0 Map13661.7RGD
Cytogenetic Map13q26UniSTS
D13Got81  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21391,029,626 - 91,029,766 (-)MAPPERmRatBN7.2
Rnor_6.01396,571,632 - 96,571,768NCBIRnor6.0
Rnor_5.013101,598,377 - 101,598,513UniSTSRnor5.0
RGSC_v3.41394,983,543 - 94,983,681RGDRGSC3.4
RGSC_v3.41394,983,544 - 94,983,681UniSTSRGSC3.4
RGSC_v3.11395,172,482 - 95,172,617RGD
Celera1390,582,253 - 90,582,390UniSTS
RH 2.0 Map13664.9RGD
Cytogenetic Map13q26UniSTS
RH141956  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21390,989,928 - 90,990,115 (-)MAPPERmRatBN7.2
Rnor_6.01396,611,294 - 96,611,480NCBIRnor6.0
Rnor_5.013101,637,799 - 101,637,985UniSTSRnor5.0
RGSC_v3.41394,943,931 - 94,944,117UniSTSRGSC3.4
Celera1390,542,559 - 90,542,745UniSTS
RH 3.4 Map13605.7UniSTS
Cytogenetic Map13q26UniSTS
BE117945  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21391,264,328 - 91,264,497 (+)MAPPERmRatBN7.2
Rnor_6.01397,805,933 - 97,806,101NCBIRnor6.0
Rnor_5.013102,815,737 - 102,815,905UniSTSRnor5.0
RGSC_v3.41395,213,960 - 95,214,128UniSTSRGSC3.4
Celera1390,816,740 - 90,816,908UniSTS
RH 3.4 Map13609.5UniSTS
Cytogenetic Map13q26UniSTS
BE118607  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21390,808,093 - 90,808,302 (+)MAPPERmRatBN7.2
Rnor_6.01397,429,211 - 97,429,419NCBIRnor6.0
Rnor_5.013102,449,103 - 102,449,311UniSTSRnor5.0
RGSC_v3.41394,742,574 - 94,742,782UniSTSRGSC3.4
Celera1390,363,852 - 90,364,060UniSTS
RH 3.4 Map13608.5UniSTS
Cytogenetic Map13q26UniSTS
RH132992  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21390,709,310 - 90,709,490 (+)MAPPERmRatBN7.2
Rnor_6.01397,330,166 - 97,330,345NCBIRnor6.0
Rnor_5.013102,350,058 - 102,350,237UniSTSRnor5.0
RGSC_v3.41394,643,762 - 94,643,941UniSTSRGSC3.4
Celera1390,265,209 - 90,265,388UniSTS
RH 3.4 Map13607.5UniSTS
Cytogenetic Map13q26UniSTS
BE102203  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21391,127,453 - 91,127,619 (+)MAPPERmRatBN7.2
Rnor_6.01397,538,052 - 97,538,217NCBIRnor6.0
Rnor_5.013102,558,863 - 102,559,028UniSTSRnor5.0
RGSC_v3.41395,084,791 - 95,084,956UniSTSRGSC3.4
Celera1390,680,011 - 90,680,176UniSTS
RH 3.4 Map13609.4UniSTS
Cytogenetic Map13q26UniSTS
AU047954  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21390,867,243 - 90,867,413 (-)MAPPERmRatBN7.2
Rnor_6.01396,731,528 - 96,731,697NCBIRnor6.0
Rnor_5.013101,757,626 - 101,757,795UniSTSRnor5.0
RGSC_v3.41394,820,650 - 94,820,819UniSTSRGSC3.4
Celera1390,420,957 - 90,421,128UniSTS
Cytogenetic Map13q26UniSTS
BE107361  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21390,915,758 - 90,915,917 (-)MAPPERmRatBN7.2
Rnor_6.01396,683,175 - 96,683,333NCBIRnor6.0
Rnor_5.013101,709,273 - 101,709,431UniSTSRnor5.0
RGSC_v3.41394,869,299 - 94,869,457UniSTSRGSC3.4
Celera1390,469,334 - 90,469,492UniSTS
RH 3.4 Map13608.5UniSTS
Cytogenetic Map13q26UniSTS


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSRNOT00000102694   ⟹   ENSRNOP00000095032
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1391,140,741 - 91,266,253 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105406   ⟹   ENSRNOP00000084109
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1390,709,270 - 91,266,253 (-)Ensembl
RefSeq Acc Id: NM_001025762   ⟹   NP_001020933
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81393,241,274 - 93,798,179 (-)NCBI
mRatBN7.21390,709,265 - 91,266,209 (-)NCBI
Rnor_6.01397,330,120 - 97,807,813 (-)NCBI
Rnor_5.013102,350,012 - 102,473,942 (-)NCBI
Rnor_5.013102,581,420 - 102,588,971 (-)NCBI
RGSC_v3.41394,643,716 - 95,108,789 (-)RGD
Celera1390,265,163 - 90,818,620 (-)RGD
Sequence:
RefSeq Acc Id: XM_039090987   ⟹   XP_038946915
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81393,241,274 - 93,704,070 (-)NCBI
mRatBN7.21390,709,263 - 91,171,384 (-)NCBI
RefSeq Acc Id: XM_039090988   ⟹   XP_038946916
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81393,241,274 - 93,701,589 (-)NCBI
mRatBN7.21390,709,263 - 91,170,101 (-)NCBI
RefSeq Acc Id: XM_039090989   ⟹   XP_038946917
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81393,241,274 - 93,686,562 (-)NCBI
mRatBN7.21390,709,263 - 91,154,588 (-)NCBI
RefSeq Acc Id: XM_063272547   ⟹   XP_063128617
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81393,620,925 - 93,798,221 (-)NCBI
RefSeq Acc Id: NP_001020933   ⟸   NM_001025762
- UniProtKB: Q4V8B9 (UniProtKB/TrEMBL),   A6JGF2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038946915   ⟸   XM_039090987
- Peptide Label: isoform X1
- UniProtKB: A6JGF2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946916   ⟸   XM_039090988
- Peptide Label: isoform X2
- UniProtKB: A6JGF2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038946917   ⟸   XM_039090989
- Peptide Label: isoform X3
- UniProtKB: A6JGF3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000095032   ⟸   ENSRNOT00000102694
Ensembl Acc Id: ENSRNOP00000084109   ⟸   ENSRNOT00000105406
RefSeq Acc Id: XP_063128617   ⟸   XM_063272547
- Peptide Label: isoform X4
- UniProtKB: A0A8I6ANX2 (UniProtKB/TrEMBL)
Protein Domains
MYND-type   SET

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562635 AgrOrtholog
BioCyc Gene G2FUF-17166 BioCyc
Ensembl Genes ENSRNOG00000066304 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000102694.1 UniProtKB/TrEMBL
  ENSRNOT00000105406.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.220.160 UniProtKB/TrEMBL
  1.25.40.10 UniProtKB/TrEMBL
  1.25.40.970 UniProtKB/TrEMBL
  2.170.270.10 UniProtKB/TrEMBL
  6.10.140.2220 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7457098 IMAGE-MGC_LOAD
InterPro H3K4_H4K5_MeTrfase UniProtKB/TrEMBL
  Hist-Lys_N-MeTrfase_Smyd3 UniProtKB/TrEMBL
  SET_dom UniProtKB/TrEMBL
  SET_dom_sf UniProtKB/TrEMBL
  SMYD3_SET UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  Znf_MYND UniProtKB/TrEMBL
KEGG Report rno:498295 UniProtKB/TrEMBL
MGC_CLONE MGC:114517 IMAGE-MGC_LOAD
NCBI Gene 498295 ENTREZGENE
PANTHER HISTONE-LYSINE N-METHYLTRANSFERASE SMYD UniProtKB/TrEMBL
  HISTONE-LYSINE N-METHYLTRANSFERASE SMYD3 UniProtKB/TrEMBL
Pfam SET UniProtKB/TrEMBL
  zf-MYND UniProtKB/TrEMBL
PhenoGen Smyd3 PhenoGen
PROSITE SAM_MT43_2 UniProtKB/TrEMBL
  SET UniProtKB/TrEMBL
  ZF_MYND_1 UniProtKB/TrEMBL
  ZF_MYND_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000066304 RatGTEx
SMART SET UniProtKB/TrEMBL
Superfamily-SCOP SSF82199 UniProtKB/TrEMBL
UniProt A0A8I6ANX2 ENTREZGENE, UniProtKB/TrEMBL
  A6JGF2 ENTREZGENE, UniProtKB/TrEMBL
  A6JGF3 ENTREZGENE, UniProtKB/TrEMBL
  Q4V8B9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-05 Smyd3  SET and MYND domain containing 3  LOC498295  similar to SET and MYND domain containing 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC498295  similar to SET and MYND domain containing 3      Symbol and Name status set to provisional 70820 PROVISIONAL