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Gene: Pld5 (phospholipase D family, member 5) Rattus norvegicus

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Symbol:

Pld5

Name:

phospholipase D family, member 5

RGD ID:

1562609

Description:

Predicted to enable hydrolase activity, acting on ester bonds. Predicted to be located in membrane. Orthologous to human PLD5 (phospholipase D family member 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

inactive phospholipase D5; LOC289270; RGD1562609; similar to hypothetical protein FLJ40773

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PLD5 (phospholipase D family member 5)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Pld5 (phospholipase D family member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Pld5 (phospholipase D family member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PLD5 (phospholipase D family member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PLD5 (phospholipase D family member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Pld5 (phospholipase D family member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PLD5 (phospholipase D family member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PLD5 (phospholipase D family member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Pld5 (phospholipase D family member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Pld5 (phospholipase D family member 5)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	PLD5 (phospholipase D family member 5)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Pld5 (phospholipase D family member 5)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	E04F6.4	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG43345	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG43345	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG9248	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	CG9248	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	Y51A2D.13	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Danio rerio (zebrafish):	pld5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

Pld5^{Tn(sb-T2/Bart3)2.340Mcwi}

Genetic Models:

F344-Pld5^{Tn(sb-T2/Bart3)2.340Mcwi}

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	90,426,689 - 90,765,072 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	90,428,490 - 90,783,066 (-)	Ensembl				GRCr8
mRatBN7.2	13	87,895,694 - 88,232,868 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	87,896,369 - 88,232,868 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	90,384,330 - 90,737,885 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	91,784,609 - 92,138,157 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	88,966,952 - 89,321,111 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	94,025,696 - 94,355,219 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	94,025,369 - 94,355,219 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	98,486,317 - 98,812,030 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	91,715,000 - 92,058,036 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	87,485,947 - 87,815,991 (-)	NCBI		Celera
Cytogenetic Map	13	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-methylcholine (ISO)

3,3',5-triiodo-L-thyronine (ISO)

3,4-dichloroaniline (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (ISO)

CGP 52608 (ISO)

cisplatin (ISO)

copper(II) chloride (ISO)

DDE (ISO)

diarsenic trioxide (ISO)

dimethylarsinic acid (EXP)

diuron (ISO)

dorsomorphin (ISO)

entinostat (ISO)

fulvestrant (ISO)

lead diacetate (ISO)

lead(0) (ISO)

methapyrilene (ISO)

methoxychlor (EXP)

methylmercury chloride (ISO)

Nutlin-3 (ISO)

okadaic acid (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

perfluorononanoic acid (ISO)

resveratrol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

thiram (ISO)

titanium dioxide (ISO)

trichostatin A (ISO)

triclosan (ISO)

valproic acid (ISO)

vorinostat (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

Molecular Function

catalytic activity (IEA)

hydrolase activity, acting on ester bonds (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
3.	Comprehensive gene review and curation	RGD comprehensive gene curation

Genomics

Comparative Map Data

Pld5
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	90,426,689 - 90,765,072 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	13	90,428,490 - 90,783,066 (-)	Ensembl				GRCr8
mRatBN7.2	13	87,895,694 - 88,232,868 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	87,896,369 - 88,232,868 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	13	90,384,330 - 90,737,885 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	91,784,609 - 92,138,157 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	88,966,952 - 89,321,111 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	94,025,696 - 94,355,219 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	94,025,369 - 94,355,219 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	13	98,486,317 - 98,812,030 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	13	91,715,000 - 92,058,036 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	13	87,485,947 - 87,815,991 (-)	NCBI		Celera
Cytogenetic Map	13	q24	NCBI

PLD5
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	242,082,986 - 242,530,546 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	242,082,986 - 242,524,697 (-)	Ensembl			hg38	GRCh38
GRCh37	1	242,246,288 - 242,687,999 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	240,318,895 - 240,754,621 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Celera	1	215,507,475 - 215,943,236 (-)	NCBI		Celera
Cytogenetic Map	1	q43	NCBI
HuRef	1	212,919,621 - 213,122,645 (-)	NCBI		HuRef
HuRef	1	212,711,210 - 212,853,533 (-)	NCBI		HuRef
CHM1_1	1	243,524,434 - 243,960,008 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	241,495,068 - 241,942,534 (-)	NCBI		T2T-CHM13v2.0

Pld5
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	175,789,867 - 176,109,078 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	175,789,872 - 176,102,878 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	1	175,962,301 - 176,281,512 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	175,962,306 - 176,275,312 (-)	Ensembl			mm10	GRCm38
MGSCv37	1	177,892,437 - 178,205,443 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	1	177,798,981 - 178,112,280 (-)	NCBI		MGSCv36	mm8
Celera	1	183,041,914 - 183,365,812 (-)	NCBI		Celera
Cytogenetic Map	1	H4	NCBI
cM Map	1	81.9	NCBI

Pld5
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	5,816,926 - 6,138,579 (-)	Ensembl
ChiLan1.0	NW_004955406	5,810,286 - 5,994,601 (-)	NCBI	ChiLan1.0	ChiLan1.0

PLD5
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	6,622,753 - 7,069,206 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	6,845,185 - 7,291,289 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	217,640,005 - 218,081,158 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	222,624,198 - 222,798,210 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

PLD5
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	33,422,964 - 33,836,252 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	33,429,409 - 33,836,258 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	32,901,116 - 33,309,816 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	33,249,160 - 33,659,927 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	33,253,065 - 33,659,964 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	33,086,377 - 33,499,628 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	33,106,517 - 33,517,045 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	33,360,227 - 33,774,810 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Pld5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	46,305,137 - 46,692,149 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936526	8,055,339 - 8,441,030 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936526	8,055,190 - 8,447,854 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLD5
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	15,420,608 - 15,723,479 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	10	15,420,600 - 15,723,890 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	17,750,621 - 17,841,790 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PLD5
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	79,164,501 - 79,584,632 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	79,171,369 - 79,519,763 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666055	81,338,470 - 81,758,441 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pld5
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624771	16,745,555 - 17,102,752 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624771	16,745,575 - 17,109,614 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Pld5
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	54,479,531 - 54,648,165 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Pld5
1939 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	59
Count of miRNA genes:	55
Interacting mature miRNAs:	58
Transcripts:	ENSRNOT00000005332
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	21120177	109350286	Rat
738027	Lnnr6	Liver neoplastic nodule remodeling QTL 6	3.3		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	65613454	109350286	Rat
7387280	Uae43	Urinary albumin excretion QTL 43	5.69	0.4174	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	68983334	109350286	Rat
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	48639634	93639634	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	67635937	109350286	Rat
1576318	Schws5	Schwannoma susceptibility QTL 5		0.0351	nervous system integrity trait (VT:0010566)	post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)	13	64497900	109350286	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	11081740	103588154	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	38975045	103588154	Rat
8655951	Rf63	Renal function QTL 63	12.2		blood urea nitrogen amount (VT:0005265)	plasma urea nitrogen level (CMO:0000586)	13	71610804	109350286	Rat
4889606	Gluco63	Glucose level QTL 63	2.86	0.003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	83286150	109350286	Rat
8655959	Pur32	Proteinuria QTL 32	8.4		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	72984506	99745408	Rat
1302791	Stl29	Serum triglyceride level QTL 29	3.3	0.0011	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	13	89333129	92500981	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	67635937	109350286	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	64375743	109350286	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	103588154	Rat
724564	Uae11	Urinary albumin excretion QTL 11	5.7		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	13	47354258	94285672	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	67635937	109350286	Rat

Markers in Region

D13Uia8

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	13	90,574,659 - 90,574,892 (+)	Marker Load Pipeline
mRatBN7.2	13	88,042,437 - 88,042,670 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	94,172,643 - 94,172,875	NCBI	Rnor6.0
Rnor_5.0	13	98,630,878 - 98,631,110	UniSTS	Rnor5.0
RGSC_v3.4	13	91,866,570 - 91,866,802	RGD	RGSC3.4
RGSC_v3.4	13	91,866,571 - 91,866,803	UniSTS	RGSC3.4
Celera	13	87,631,483 - 87,631,715	UniSTS
RGSC_v3.1	13	92,055,454 - 92,055,686	RGD
Cytogenetic Map	13	q25	UniSTS

Genetic Models

This gene Pld5 is modified in the following models/strains:

F344-Pld5^{Tn(sb-T2/Bart3)2.340Mcwi}

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
12	12	62	141	61	57	29	24	29	6	225	119	11	113	57	76	28	12	12

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001191674	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090526	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090527	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039090528	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000005332 ⟹ ENSRNOP00000005332

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	90,428,490 - 90,783,066 (-)	Ensembl
mRatBN7.2 Ensembl	13	87,896,369 - 88,232,868 (-)	Ensembl
Rnor_6.0 Ensembl	13	94,025,696 - 94,355,219 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078195 ⟹ ENSRNOP00000069712

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	90,428,490 - 90,692,903 (-)	Ensembl
mRatBN7.2 Ensembl	13	87,896,369 - 88,160,843 (-)	Ensembl
Rnor_6.0 Ensembl	13	94,025,369 - 94,289,333 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000139537 ⟹ ENSRNOP00000106787

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	13	90,428,490 - 90,701,102 (-)	Ensembl

RefSeq Acc Id:

NM_001191674 ⟹ NP_001178603

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	90,428,490 - 90,765,072 (-)	NCBI
mRatBN7.2	13	87,896,369 - 88,232,868 (-)	NCBI
Rnor_6.0	13	94,025,696 - 94,355,219 (-)	NCBI
Rnor_5.0	13	98,486,317 - 98,812,030 (-)	NCBI
Celera	13	87,485,947 - 87,815,991 (-)	NCBI

Sequence:

show sequence

ATGGAGATCCGGCAGCACGAGTGGCTCTCGGCCTCCCCCCACGAGGGTTTCGAGCAGATGAGAT
TGAAAAGCCGCCCCAAGGAACCCTCGCCCAGCCTGACCCGAGTGGGCGCGAACTTCTACAGCAG
TGTCAAGCAGCAGGACTACAGCGCCAGCGTCTGGCTCCGGAGGAAAGATAAGCTGGAACACTCC
CAGCAGAAGTGCATTGTGATCTTCGCTCTGGTCTGCTGCTTCGCCGTTCTGGTCGCACTGATCT
TTTCAGCTGTGGACATCATGGGAGAGGATGAGGATGGACTCTCGGAGAAGAATTGCCAAAATAA
ATGTCGAATCGCTCTTGTGGAAAACATTCCTGAAGGCCTTAACTACTCTGAGGATGCCCCATTT
CACTTACCGCTCTTCCAAGGCTGGATGAACTTACTCAACATGGCCAAAAAGTCTGTCGACATAG
TGTCTTCCCATTGGGACCTCAACCACACCCACCCATCTGCATGTCAGGGTCAACGTCTCTTTGA
GAAATTGCTCCAGCTGACGTCGCAAAATATTGAAGTCAAGCTGGTGAGCGATGTGACTGCAGAT
TCAAAGGTATTAGAAGCCTTGAAGTTAAAGGGCGCTGAGGTGACATACATGAACATGACCGCCT
ACAACAAGGGCCGGCTGCAGTCGTCCTTCTGGATTGTGGACAAACAGCACGTGTACATCGGCAG
CGCAGGCTTAGACTGGCGATCGCTTGGACAGATGAAAGAACTCGGTGTCATCTTCTACAACTGC
AGCTGCCTGGTCCTAGATTTACAGAGGATATTCGCTTTATATAGCTCATTAAAATTCAAGAGCA
GAGTACCTCAGACCTGGTCCAAGAGACTCTATGGAGTCTATGACAATGAAAAGAAGCTTCAGCT
CCAATTGAACGAAACCAAGTCGCAGGCCTTTGTGTCGAACTCTCCCAAACTCTTTTGCCCTAAA
AACAGAAGCTTTGACATTGATGCCATCTACAGCGTGATTGATGATGCCAAACAGTATGTGTACA
TTGCTGTCACGGACTACCTGCCTATTTCCAGCACGAGCACCAAAAGGACTTACTGGCCAGATTT
AGATGGGAAAATAAGAGAAGCATTAGTTTTACGAAGCGTTAAAGTCCGGCTGCTCATAAGCTTT
TGGAAGGAGACTGATCCCCTCACGTTTAACTTCATTTCGTCTCTTAAGGCTATTTGCACTGAAA
TAGCCAACTGCAGTTTGAAAGTTAAATTTTTTGATCTGGAAAGAGAGAACGCTTGTGCAACAAA
AGAACAAAAGAACCAGACCTTTCCCAAATTAAACCGCAACAAGTACATGGTGACAGATGGTGCA
GCTTACATTGGAAATTTTGACTGGGTGGGGAATGACTTTACCCAGAATGCTGGCACGGGCCTTG
TCATCAACCAGGCAGATGTGAGAGACAACAGGAGCATCATTAAGCAACTTAAAGACGTGTTTGA
GAGGGACTGGTATTCACCTTATGCCAAATCTATACAGCCAACCAAACAGCCGAACTGTTCAAAC
CTGTCCAAACTCAAGACTCCCTCCAACCAACCTGCTATTTACAACACCACAGGGAGGGAGCCCC
TGAGTGTATAGCTCACTAAGAGACAAGCAAGGCTTCAGACCAAATGCAGGAAGGACTAGAGGAA
AGACAACGATTTGTTACATCTTTTTTTTAAAAGGGGAAATTAAAAAGCACACTTAT

hide sequence

RefSeq Acc Id:

XM_039090526 ⟹ XP_038946454

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	90,426,689 - 90,700,682 (-)	NCBI
mRatBN7.2	13	87,896,478 - 88,167,604 (-)	NCBI

RefSeq Acc Id:

XM_039090527 ⟹ XP_038946455

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	90,426,689 - 90,611,088 (-)	NCBI
mRatBN7.2	13	87,896,478 - 88,078,855 (-)	NCBI

RefSeq Acc Id:

XM_039090528 ⟹ XP_038946456

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	90,426,689 - 90,611,088 (-)	NCBI
mRatBN7.2	13	87,895,694 - 88,030,809 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001178603	(Get FASTA)	NCBI Sequence Viewer
	XP_038946454	(Get FASTA)	NCBI Sequence Viewer
	XP_038946455	(Get FASTA)	NCBI Sequence Viewer
	XP_038946456	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL94778	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000005332
	ENSRNOP00000005332.6
	ENSRNOP00000069712
	ENSRNOP00000069712.1
	ENSRNOP00000106787.1

RefSeq Acc Id:

NP_001178603 ⟸ NM_001191674

- UniProtKB:

F1MA92 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEIRQHEWLSASPHEGFEQMRLKSRPKEPSPSLTRVGANFYSSVKQQDYSASVWLRRKDKLEHS
QQKCIVIFALVCCFAVLVALIFSAVDIMGEDEDGLSEKNCQNKCRIALVENIPEGLNYSEDAPF
HLPLFQGWMNLLNMAKKSVDIVSSHWDLNHTHPSACQGQRLFEKLLQLTSQNIEVKLVSDVTAD
SKVLEALKLKGAEVTYMNMTAYNKGRLQSSFWIVDKQHVYIGSAGLDWRSLGQMKELGVIFYNC
SCLVLDLQRIFALYSSLKFKSRVPQTWSKRLYGVYDNEKKLQLQLNETKSQAFVSNSPKLFCPK
NRSFDIDAIYSVIDDAKQYVYIAVTDYLPISSTSTKRTYWPDLDGKIREALVLRSVKVRLLISF
WKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNQTFPKLNRNKYMVTDGA
AYIGNFDWVGNDFTQNAGTGLVINQADVRDNRSIIKQLKDVFERDWYSPYAKSIQPTKQPNCSN
LSKLKTPSNQPAIYNTTGREPLSV

hide sequence

Ensembl Acc Id:

ENSRNOP00000069712 ⟸ ENSRNOT00000078195

Ensembl Acc Id:

ENSRNOP00000005332 ⟸ ENSRNOT00000005332

RefSeq Acc Id:	XP_038946456 ⟸ XM_039090528
- Peptide Label:	isoform X3
- UniProtKB:	A6JGC2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038946454 ⟸ XM_039090526
- Peptide Label:	isoform X1
- UniProtKB:	A0A0G2JW24 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038946455 ⟸ XM_039090527
- Peptide Label:	isoform X2

Ensembl Acc Id:

ENSRNOP00000106787 ⟸ ENSRNOT00000139537

Protein Domains

PLD phosphodiesterase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1MA92-F1-model_v2	AlphaFold	F1MA92	1-536	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1562609	AgrOrtholog
BioCyc Gene	G2FUF-17214	BioCyc
Ensembl Genes	ENSRNOG00000003997	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000005332	ENTREZGENE
	ENSRNOT00000005332.8	UniProtKB/TrEMBL
	ENSRNOT00000078195	ENTREZGENE
	ENSRNOT00000078195.3	UniProtKB/TrEMBL
	ENSRNOT00000139537.1	UniProtKB/TrEMBL
Gene3D-CATH	Endonuclease Chain A	UniProtKB/TrEMBL
InterPro	Diverse_PLD-related	UniProtKB/TrEMBL
	PLDc_3	UniProtKB/TrEMBL
	PLipase_D/transphosphatidylase	UniProtKB/TrEMBL
KEGG Report	rno:289270	UniProtKB/TrEMBL
NCBI Gene	289270	ENTREZGENE
PANTHER	INACTIVE PHOSPHOLIPASE D5	UniProtKB/TrEMBL
	PHOSPHOLIPASE D - RELATED	UniProtKB/TrEMBL
Pfam	PLDc_3	UniProtKB/TrEMBL
PhenoGen	Pld5	PhenoGen
PROSITE	PLD	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000003997	RatGTEx
SMART	PLDc	UniProtKB/TrEMBL
Superfamily-SCOP	Phospholipase D/nuclease	UniProtKB/TrEMBL
UniProt	A0A0G2JW24	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0LMB5_RAT	UniProtKB/TrEMBL
	A6JGC2	ENTREZGENE, UniProtKB/TrEMBL
	F1MA92	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-29	Pld5	phospholipase D family, member 5	RGD1562609_predicted	similar to hypothetical protein FLJ40773 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-07	RGD1562609_predicted	similar to hypothetical protein FLJ40773 (predicted)	LOC289270	similar to hypothetical protein FLJ40773	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC289270	similar to hypothetical protein FLJ40773			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD