Tra2a (transformer 2 alpha) - Rat Genome Database

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Gene: Tra2a (transformer 2 alpha) Rattus norvegicus
Analyze
Symbol: Tra2a
Name: transformer 2 alpha
RGD ID: 1562563
Description: Predicted to enable RNA binding activity and identical protein binding activity. Predicted to be involved in mRNA splicing, via spliceosome and positive regulation of mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of spliceosomal complex. Orthologous to human TRA2A (transformer 2 alpha homolog); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC500116; RGD1562563; similar to RIKEN cDNA G430041M01; transformer 2 alpha homolog; transformer 2 alpha homolog (Drosophila); transformer-2 alpha; transformer-2 protein homolog alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Tra2a-ps1   Tra2a-ps3  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8479,551,699 - 79,570,621 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl479,551,542 - 79,570,619 (-)EnsemblGRCr8
mRatBN7.2478,220,838 - 78,239,737 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl478,220,883 - 78,239,712 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx483,428,208 - 83,447,107 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0479,203,649 - 79,222,547 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0477,643,981 - 77,662,880 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0478,905,380 - 78,924,203 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl478,905,380 - 78,924,181 (-)Ensemblrn6Rnor6.0
Rnor_5.04143,594,550 - 143,613,369 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4477,372,546 - 77,391,417 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera473,156,096 - 73,174,981 (-)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-phenylbutyric acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chlormequat chloride  (EXP)
chloroprene  (EXP)
cisplatin  (ISO)
clobetasol  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dimethylarsinic acid  (ISO)
elemental selenium  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
graphene oxide  (ISO)
ivermectin  (ISO)
ketamine  (EXP)
leflunomide  (ISO)
levonorgestrel  (ISO)
methylarsonic acid  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodimethylamine  (ISO)
nicotine  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
piroxicam  (ISO)
progesterone  (ISO)
quercetin  (ISO)
resveratrol  (EXP)
rotenone  (ISO)
selenium atom  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
testosterone  (ISO)
testosterone enanthate  (ISO)
testosterone undecanoate  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vitamin E  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleolus  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO)
spliceosomal complex  (IBA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. The interaction and colocalization of Sam68 with the splicing-associated factor YT521-B in nuclear dots is regulated by the Src family kinase p59(fyn). Hartmann AM, etal., Mol Biol Cell 1999 Nov;10(11):3909-26.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9546399   PMID:11401487   PMID:12477932   PMID:16249178   PMID:22194695   PMID:22658674   PMID:22681889  


Genomics

Comparative Map Data
Tra2a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8479,551,699 - 79,570,621 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl479,551,542 - 79,570,619 (-)EnsemblGRCr8
mRatBN7.2478,220,838 - 78,239,737 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl478,220,883 - 78,239,712 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx483,428,208 - 83,447,107 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0479,203,649 - 79,222,547 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0477,643,981 - 77,662,880 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0478,905,380 - 78,924,203 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl478,905,380 - 78,924,181 (-)Ensemblrn6Rnor6.0
Rnor_5.04143,594,550 - 143,613,369 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4477,372,546 - 77,391,417 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera473,156,096 - 73,174,981 (-)NCBICelera
Cytogenetic Map4q24NCBI
TRA2A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38723,504,780 - 23,531,981 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl723,504,780 - 23,532,041 (-)Ensemblhg38GRCh38
GRCh37723,544,399 - 23,571,600 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36723,510,924 - 23,538,181 (-)NCBIBuild 36Build 36hg18NCBI36
Celera723,533,162 - 23,560,412 (-)NCBICelera
Cytogenetic Map7p15.3NCBI
HuRef723,429,165 - 23,456,678 (-)NCBIHuRef
CHM1_1723,545,328 - 23,572,796 (-)NCBICHM1_1
T2T-CHM13v2.0723,644,119 - 23,671,311 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2723,596,242 - 23,623,480 (-)NCBI
Tra2a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39649,220,855 - 49,241,182 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl649,220,858 - 49,240,967 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38649,243,921 - 49,264,248 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl649,243,924 - 49,264,033 (-)Ensemblmm10GRCm38
MGSCv37649,193,920 - 49,214,051 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36649,173,510 - 49,193,596 (-)NCBIMGSCv36mm8
Celera649,753,711 - 49,773,900 (-)NCBICelera
Cytogenetic Map6B2.3NCBI
cM Map623.84NCBI
Tra2a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541025,759,649 - 25,784,128 (-)Ensembl
ChiLan1.0NW_00495541025,759,649 - 25,784,128 (-)NCBIChiLan1.0ChiLan1.0
TRA2A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2628,367,004 - 28,396,060 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1776,691,730 - 76,720,786 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0724,184,844 - 24,213,889 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1723,791,748 - 23,820,124 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl723,791,479 - 23,820,124 (-)EnsemblpanPan2panpan1.1
TRA2A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11437,159,890 - 37,183,457 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1437,160,872 - 37,183,274 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1436,699,986 - 36,723,267 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01437,090,337 - 37,113,702 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1437,090,121 - 37,114,152 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11437,205,864 - 37,229,212 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01436,901,476 - 36,924,794 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01437,239,049 - 37,262,831 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tra2a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511881,410,829 - 81,430,993 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936478623,342 - 642,525 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936478622,527 - 642,529 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRA2A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl992,294,917 - 92,323,794 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1992,299,171 - 92,323,789 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29101,626,648 - 101,651,251 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRA2A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12134,787,839 - 34,816,299 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2134,787,827 - 34,816,881 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604269,793,916 - 69,822,757 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tra2a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247397,076,828 - 7,126,734 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247397,076,822 - 7,126,734 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tra2a
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1691,716,404 - 91,734,510 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tra2a
117 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:285
Count of miRNA genes:186
Interacting mature miRNAs:217
Transcripts:ENSRNOT00000012325
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)439431983123203361Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)459753119104753119Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44140057786400577Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44442502489425024Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)458817672103817672Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)426234499134199155Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)474233320119233320Rat
61336Bp21Blood pressure QTL 214.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45808014680212111Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)471647492116647492Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)427862204126119996Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44140060386400603Rat
61476Aia3Adjuvant induced arthritis QTL 33.9joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)475939858140508796Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)43044896182336920Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)465060960127749483Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)445429897149763204Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)451085655113588029Rat
2317588Eae27Experimental allergic encephalomyelitis QTL 27nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)469036742114036742Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)440490442117737312Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)457613339151163960Rat
4889969Bss96Bone structure and strength QTL 964.9tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)457613242102613242Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
4889972Bss97Bone structure and strength QTL 975.6tibia size trait (VT:0100001)tibia total bone volume (CMO:0001724)457613242102613242Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
5685012Bmd87Bone mineral density QTL 875.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)43511329080113290Rat
5685009Bmd86Bone mineral density QTL 863.7tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)457613242102613242Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)45807987582597589Rat
2306547Iddm38Insulin dependent diabetes mellitus QTL 38blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)468353567113353567Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
2306545Iddm39Insulin dependent diabetes mellitus QTL 39blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478687630123687630Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41170660492690519Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)474169813134199155Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)459836842104836842Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)43726957782269577Rat
61406Scwia1Streptococcal cell wall induced arthritis QTL 12.3joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)475939858140508796Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)445429897149763204Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)46104105794638356Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45889999148002343Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463245026129846354Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)464209744109209744Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)44140057786400577Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)457664252127749483Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45807987592690793Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)464084079109084079Rat
61434Cia3Collagen induced arthritis QTL 34.8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)463224393108224393Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46390045888813920Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)433538597116185060Rat
631671Iddm11Insulin dependent diabetes mellitus QTL 113.60.0012blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)45960331980216952Rat

Markers in Region
AI713502  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,220,952 - 78,221,047 (+)MAPPERmRatBN7.2
Rnor_6.0478,905,495 - 78,905,589NCBIRnor6.0
Rnor_5.04143,594,665 - 143,594,759UniSTSRnor5.0
RGSC_v3.4477,372,613 - 77,372,707UniSTSRGSC3.4
Celera473,156,211 - 73,156,305UniSTS
RH 3.4 Map4501.7UniSTS
Cytogenetic Map4q24UniSTS
BF399092  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,238,823 - 78,238,980 (+)MAPPERmRatBN7.2
Rnor_6.0478,923,281 - 78,923,437NCBIRnor6.0
Rnor_5.04143,612,451 - 143,612,607UniSTSRnor5.0
RGSC_v3.4477,390,510 - 77,390,666UniSTSRGSC3.4
Celera473,174,081 - 73,174,237UniSTS
RH 3.4 Map4490.3UniSTS
Cytogenetic Map4q24UniSTS
RH139998  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2478,229,801 - 78,229,992 (+)MAPPERmRatBN7.2
Rnor_6.0478,914,344 - 78,914,534NCBIRnor6.0
Rnor_5.04143,603,514 - 143,603,704UniSTSRnor5.0
RGSC_v3.4477,381,462 - 77,381,652UniSTSRGSC3.4
Celera473,165,060 - 73,165,250UniSTS
RH 3.4 Map4500.3UniSTS
Cytogenetic Map4q24UniSTS
RH44636  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2661,841,215 - 61,841,338 (+)MAPPERmRatBN7.2
Rnor_6.0665,007,557 - 65,007,679NCBIRnor6.0
Rnor_5.0674,589,252 - 74,589,374UniSTSRnor5.0
RGSC_v3.4664,166,656 - 64,166,778UniSTSRGSC3.4
Celera660,827,977 - 60,828,099UniSTS
Cytogenetic Map4q24UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000012325   ⟹   ENSRNOP00000012325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl479,551,699 - 79,570,619 (-)Ensembl
mRatBN7.2 Ensembl478,220,883 - 78,239,712 (-)Ensembl
Rnor_6.0 Ensembl478,905,380 - 78,924,181 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000096480   ⟹   ENSRNOP00000082266
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl479,551,542 - 79,570,584 (-)Ensembl
mRatBN7.2 Ensembl478,221,827 - 78,227,364 (-)Ensembl
RefSeq Acc Id: NM_001126296   ⟹   NP_001119768
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8479,551,699 - 79,570,584 (-)NCBI
mRatBN7.2478,220,838 - 78,239,724 (-)NCBI
Rnor_6.0478,905,380 - 78,924,181 (-)NCBI
Rnor_5.04143,594,550 - 143,613,369 (-)NCBI
RGSC_v3.4477,372,546 - 77,391,417 (-)RGD
Celera473,156,096 - 73,174,981 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006236464   ⟹   XP_006236526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8479,551,744 - 79,570,597 (-)NCBI
mRatBN7.2478,220,883 - 78,239,737 (-)NCBI
Rnor_6.0478,905,423 - 78,924,203 (-)NCBI
Rnor_5.04143,594,550 - 143,613,369 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006236465   ⟹   XP_006236527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8479,551,744 - 79,570,621 (-)NCBI
mRatBN7.2478,220,883 - 78,239,737 (-)NCBI
Rnor_6.0478,905,423 - 78,924,203 (-)NCBI
Rnor_5.04143,594,550 - 143,613,369 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006236466   ⟹   XP_006236528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8479,551,744 - 79,570,597 (-)NCBI
mRatBN7.2478,220,883 - 78,239,737 (-)NCBI
Rnor_6.0478,905,423 - 78,924,203 (-)NCBI
Rnor_5.04143,594,550 - 143,613,369 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592792   ⟹   XP_017448281
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8479,551,744 - 79,570,590 (-)NCBI
mRatBN7.2478,220,883 - 78,239,737 (-)NCBI
Rnor_6.0478,905,423 - 78,919,155 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039108127   ⟹   XP_038964055
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8479,551,744 - 79,570,597 (-)NCBI
mRatBN7.2478,220,883 - 78,239,736 (-)NCBI
RefSeq Acc Id: XM_063286509   ⟹   XP_063142579
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8479,551,744 - 79,570,597 (-)NCBI
RefSeq Acc Id: XM_063286510   ⟹   XP_063142580
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8479,551,744 - 79,570,597 (-)NCBI
RefSeq Acc Id: XM_063286511   ⟹   XP_063142581
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8479,551,744 - 79,570,597 (-)NCBI
RefSeq Acc Id: NP_001119768   ⟸   NM_001126296
- UniProtKB: B1WC25 (UniProtKB/TrEMBL),   F7ESB6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006236527   ⟸   XM_006236465
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006236526   ⟸   XM_006236464
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006236528   ⟸   XM_006236466
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_017448281   ⟸   XM_017592792
- Peptide Label: isoform X8
- Sequence:
Ensembl Acc Id: ENSRNOP00000012325   ⟸   ENSRNOT00000012325
RefSeq Acc Id: XP_038964055   ⟸   XM_039108127
- Peptide Label: isoform X1
Ensembl Acc Id: ENSRNOP00000082266   ⟸   ENSRNOT00000096480
RefSeq Acc Id: XP_063142581   ⟸   XM_063286511
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063142580   ⟸   XM_063286510
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063142579   ⟸   XM_063286509
- Peptide Label: isoform X3
- UniProtKB: A0A8J8Y9E0 (UniProtKB/TrEMBL)
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B1WC25-F1-model_v2 AlphaFold B1WC25 1-282 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693037
Promoter ID:EPDNEW_R3560
Type:multiple initiation site
Name:Tra2a_1
Description:transformer 2 alpha homolog
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0478,924,176 - 78,924,236EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562563 AgrOrtholog
BioCyc Gene G2FUF-44922 BioCyc
Ensembl Genes ENSRNOG00000009156 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012325 ENTREZGENE
  ENSRNOT00000012325.9 UniProtKB/TrEMBL
  ENSRNOT00000096480 ENTREZGENE
  ENSRNOT00000096480.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9029930 IMAGE-MGC_LOAD
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RBM UniProtKB/TrEMBL
  RRM_RNP1 UniProtKB/TrEMBL
KEGG Report rno:500116 UniProtKB/TrEMBL
MGC_CLONE MGC:187790 IMAGE-MGC_LOAD
NCBI Gene 500116 ENTREZGENE
PANTHER TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PhenoGen Tra2a PhenoGen
PROSITE RRM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009156 RatGTEx
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A8I5ZXL0_RAT UniProtKB/TrEMBL
  A0A8J8Y9E0 ENTREZGENE, UniProtKB/TrEMBL
  B1WC25 ENTREZGENE, UniProtKB/TrEMBL
  F7ESB6 ENTREZGENE
UniProt Secondary F7ESB6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-03-14 Tra2a  transformer 2 alpha  Tra2a  transformer 2 alpha homolog  Name changed 629549 APPROVED
2016-04-20 Tra2a  transformer 2 alpha homolog  Tra2a  transformer 2 alpha homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 Tra2a  transformer 2 alpha homolog (Drosophila)  Tra2a  transformer-2 alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-15 Tra2a  transformer-2 alpha  Tra2a  transformer 2 alpha homolog (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-29 Tra2a  transformer 2 alpha homolog (Drosophila)  RGD1562563_predicted  similar to RIKEN cDNA G430041M01 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1562563_predicted  similar to RIKEN cDNA G430041M01 (predicted)  LOC500116  similar to RIKEN cDNA G430041M01  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC500116  similar to RIKEN cDNA G430041M01      Symbol and Name status set to provisional 70820 PROVISIONAL