Tmem267 (transmembrane protein 267) - Rat Genome Database

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Gene: Tmem267 (transmembrane protein 267) Rattus norvegicus
Analyze
Symbol: Tmem267
Name: transmembrane protein 267
RGD ID: 1562550
Description: Predicted to be located in membrane. Orthologous to human TMEM267 (transmembrane protein 267); INTERACTS WITH (+)-schisandrin B; bisphenol A; gentamycin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC499532; RGD1562550; similar to hypothetical protein FLJ21657; transmembrane protein C5orf28 homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8253,309,857 - 53,321,466 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl253,313,021 - 53,320,835 (+)EnsemblGRCr8
mRatBN7.2251,580,210 - 51,588,937 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl251,581,252 - 51,587,636 (+)EnsemblmRatBN7.2
Rnor_6.0252,356,449 - 52,366,075 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl252,358,097 - 52,366,667 (+)Ensemblrn6Rnor6.0
Rnor_5.0270,720,399 - 70,729,089 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4251,671,281 - 51,674,154 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera247,233,460 - 47,243,086 (+)NCBICelera
Cytogenetic Map2q15NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Tmem267
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8253,309,857 - 53,321,466 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl253,313,021 - 53,320,835 (+)EnsemblGRCr8
mRatBN7.2251,580,210 - 51,588,937 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl251,581,252 - 51,587,636 (+)EnsemblmRatBN7.2
Rnor_6.0252,356,449 - 52,366,075 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl252,358,097 - 52,366,667 (+)Ensemblrn6Rnor6.0
Rnor_5.0270,720,399 - 70,729,089 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4251,671,281 - 51,674,154 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera247,233,460 - 47,243,086 (+)NCBICelera
Cytogenetic Map2q15NCBI
TMEM267
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38543,444,252 - 43,484,387 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl543,444,252 - 43,484,476 (-)Ensemblhg38GRCh38
GRCh37543,444,354 - 43,484,489 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36543,480,111 - 43,515,847 (-)NCBIBuild 36Build 36hg18NCBI36
Celera543,335,476 - 43,375,118 (-)NCBICelera
Cytogenetic Map5p12NCBI
HuRef543,395,477 - 43,435,115 (-)NCBIHuRef
CHM1_1543,445,666 - 43,485,257 (-)NCBICHM1_1
T2T-CHM13v2.0543,697,085 - 43,737,220 (-)NCBIT2T-CHM13v2.0
Tmem267
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913119,624,622 - 120,071,995 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13119,624,575 - 120,072,595 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3813119,488,086 - 119,610,459 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13119,488,039 - 119,611,059 (+)Ensemblmm10GRCm38
MGSCv3713120,276,846 - 120,284,312 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3613120,606,912 - 120,614,378 (+)NCBIMGSCv36mm8
Celera13123,986,224 - 123,989,137 (+)NCBICelera
Cytogenetic Map13D2.3NCBI
cM Map1367.25NCBI
Tmem267
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544618,879,661 - 18,888,220 (+)Ensembl
ChiLan1.0NW_00495544618,865,735 - 18,888,356 (+)NCBIChiLan1.0ChiLan1.0
TMEM267
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2466,840,627 - 66,880,558 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1564,994,219 - 65,034,184 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0566,888,217 - 66,928,369 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1571,938,468 - 71,978,418 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl571,943,053 - 71,978,418 (+)EnsemblpanPan2panpan1.1
TMEM267
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1466,530,666 - 66,548,575 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl466,531,649 - 66,551,923 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha466,291,083 - 66,311,188 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0467,022,804 - 67,043,029 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl467,023,132 - 67,043,032 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1466,780,875 - 66,800,966 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0466,911,534 - 66,931,609 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0467,447,101 - 67,467,437 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Tmem267
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213209,822,779 - 209,856,486 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648018,782,715 - 18,793,070 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648018,764,689 - 18,793,088 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM267
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1628,027,425 - 28,042,884 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11628,027,401 - 28,060,633 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21629,547,350 - 29,565,568 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM267
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1442,223,968 - 42,267,658 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl442,223,684 - 42,271,263 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366607132,690,237 - 32,740,190 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem267
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475911,733,039 - 11,745,444 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462475911,733,293 - 11,747,103 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Tmem267
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13177,283,081 - 177,289,977 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Tmem267
86 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:12
Count of miRNA genes:12
Interacting mature miRNAs:12
Transcripts:ENSRNOT00000037659
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21332504158325041Rat
7387318Stl32Serum triglyceride level QTL 323.20.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)22411781369117813Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23675034481750344Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1300160Hrtrt3Heart rate QTL 33.62heart pumping trait (VT:2000009)absolute change in heart rate (CMO:0000534)23561408353462005Rat
1579916Bp270Blood pressure QTL 2700.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21605188361051883Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22203804467038044Rat
731166Mamtr2Mammary tumor resistance QTL 20.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358154623581Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)240306867124537199Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22888999173889991Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)241801363104744824Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21436870759368707Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24490435585286097Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979159440891Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)244537979112567334Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266683465677Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)25126685996266859Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)238426449111295694Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21822713763227137Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23686864381868643Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)24490435589904355Rat
1582246Cm60Cardiac mass QTL 605.8heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)23326999678269996Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266673652666Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 165 91 90 59 87 59 6 350 186 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000037659   ⟹   ENSRNOP00000031867
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl252,358,097 - 52,366,667 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095967   ⟹   ENSRNOP00000091745
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl253,313,021 - 53,320,835 (+)Ensembl
mRatBN7.2 Ensembl251,581,252 - 51,587,636 (+)Ensembl
RefSeq Acc Id: NM_001427857   ⟹   NP_001414786
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8253,312,986 - 53,320,835 (+)NCBI
RefSeq Acc Id: XM_006231978   ⟹   XP_006232040
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8253,309,857 - 53,320,835 (+)NCBI
mRatBN7.2251,580,407 - 51,588,120 (+)NCBI
Rnor_6.0252,358,364 - 52,366,075 (+)NCBI
Rnor_5.0270,720,399 - 70,729,089 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006231979   ⟹   XP_006232041
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8253,309,857 - 53,320,835 (+)NCBI
mRatBN7.2251,580,407 - 51,588,120 (+)NCBI
Rnor_6.0252,358,364 - 52,366,075 (+)NCBI
Rnor_5.0270,720,399 - 70,729,089 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008760799   ⟹   XP_008759021
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8253,313,663 - 53,320,835 (+)NCBI
mRatBN7.2251,580,952 - 51,588,120 (+)NCBI
Rnor_6.0252,358,603 - 52,366,075 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039103522   ⟹   XP_038959450
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8253,309,857 - 53,321,466 (+)NCBI
mRatBN7.2251,580,407 - 51,588,937 (+)NCBI
RefSeq Acc Id: XM_063282347   ⟹   XP_063138417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8253,309,857 - 53,321,466 (+)NCBI
RefSeq Acc Id: XP_006232040   ⟸   XM_006231978
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006232041   ⟸   XM_006231979
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008759021   ⟸   XM_008760799
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AG39 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000031867   ⟸   ENSRNOT00000037659
RefSeq Acc Id: XP_038959450   ⟸   XM_039103522
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000091745   ⟸   ENSRNOT00000095967
RefSeq Acc Id: XP_063138417   ⟸   XM_063282347
- Peptide Label: isoform X5
RefSeq Acc Id: NP_001414786   ⟸   NM_001427857

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LUB0-F1-model_v2 AlphaFold F1LUB0 1-238 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1562550 AgrOrtholog
BioCyc Gene G2FUF-54287 BioCyc
Ensembl Genes ENSRNOG00000027263 Ensembl
  ENSRNOG00000064070 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000095967 ENTREZGENE
  ENSRNOT00000095967.2 UniProtKB/TrEMBL
InterPro TMEM267 UniProtKB/TrEMBL
NCBI Gene 499532 ENTREZGENE
PANTHER PTHR13628 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 267 UniProtKB/TrEMBL
PhenoGen Tmem267 PhenoGen
RatGTEx ENSRNOG00000027263 RatGTEx
  ENSRNOG00000064070 RatGTEx
UniProt A0A8I6AG39 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-01 Tmem267  transmembrane protein 267  Tmem267  transmembrane protein 267  Data merged from RGD:149736404 737654 PROVISIONAL
2021-08-09 Tmem267  transmembrane protein 267      Symbol and Name status set to provisional 45752 PROVISIONAL
2016-05-31 Tmem267  transmembrane protein 267  RGD1562550  similar to hypothetical protein FLJ21657  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1562550  similar to hypothetical protein FLJ21657   RGD1562550_predicted  similar to hypothetical protein FLJ21657 (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1562550_predicted  similar to hypothetical protein FLJ21657 (predicted)  LOC499532  similar to hypothetical protein FLJ21657  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC499532  similar to hypothetical protein FLJ21657      Symbol and Name status set to provisional 70820 PROVISIONAL